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The map label for this gene is thiL [H]

Identifier: 119896801

GI number: 119896801

Start: 546104

End: 547114

Strand: Reverse

Name: thiL [H]

Synonym: azo0510

Alternate gene names: 119896801

Gene position: 547114-546104 (Counterclockwise)

Preceding gene: 119896802

Following gene: 119896800

Centisome position: 12.5

GC content: 73.89

Gene sequence:

>1011_bases
ATGCCCAGTTCCGCCCCGGCCTCCCGCCAGAACGCACCCGACGCCGCCGCCACGACAGCGGGCGAATTCGCGCTGATCCA
GCGCCACTTCTCGCGCCCCTGCGGACACACCGCGCTCGCCGGCGGCGACGATGCCGCCCTGCTGCACCCACGCCCCGGCA
TGGAACTCGCCGTGTCGGCCGACATGCTGGTGGCCGGCACCCATTTCTTTCCCGATGCCGACCCTCACGACCTGGGCTGG
AAGACGCTCGCGGTCAATGTGTCCGATCTGGCCGCAATGGGCGCGGATCCGCGCTGGGCGCTGCTGTCGCTCGCGCTGCC
CGCGGCAGACGACGCCTGGATCGCCGCCTTCGCGGACGGCTTCTATGCCTGTGCCGAACGCTTCGGCGTGGACCTCGCCG
GCGGCGACACCACGCGCGGGCCGCTCACGCTTTCGGTAACCATCCTGGGCGAAGTCCCGCGCGGACAGGCGCTGACCCGC
GCCGGCGCCAATGCGGGCGACGACATCTGGGTATCGGGGCAGCCGGGGCTTGCCGCGCTCGGGCTCGAAATGTTGCGCGG
CACGTTCGCCCCCACGGCCGACGGCGAGCGTTGCCTCGCCGCGCTGCATCGCCCGCAACCGCGCGTCGCGCTGGGACAGG
CGCTGCGCGGGCTGGCCAGCGCCGCGCTCGACATCTCCGACGGCCTGCTCGGCGACCTCGGCCATATCCTGGTGCAATCG
CGCTGCGGCGCCACGCTGCATGAGGACGCGCTACCGCTCGCCGCGCTGTACGCCACCGGCGCCAGCCCCGCTCTCGCGCG
GCGCTGCCTGCTGGCGGGCGGCGACGACTATGAACTGCTGTTCTGCGCCCCCCCGGCCGCCCGCGCGGCGATCACCGCCC
TGGGCCCCGCGCTGGCACTGCCGCTGACCCGCATCGGCACCCTCAGCGATGCGCCTGGCACGGTGGCCCTGCGTAGCGCC
GATGGCACCCTCACCGCCCTCGCCGCCCGCGGCTACGACCACTTCGGCTGA

Upstream 100 bases:

>100_bases
CGCGCCGCGCTTCGTCCTGCGGACGGCGCCGCGGCACTGCGGTAAGCTCGCGGCTTTCCAGCCCCAGCGCCGCTGCATCC
ATGCCGGCGCGATTGCGCCG

Downstream 100 bases:

>100_bases
CCCATGCGCCCCACGCTCCGCCTGCTGCTGTCCCATCCAGCGCACTTCATTTCGCTCGGCTTCGGTGCCGGGCTCTCGCC
ACGGGCACCGGGCACCGTGG

Product: thiamine-phosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MPSSAPASRQNAPDAAATTAGEFALIQRHFSRPCGHTALAGGDDAALLHPRPGMELAVSADMLVAGTHFFPDADPHDLGW
KTLAVNVSDLAAMGADPRWALLSLALPAADDAWIAAFADGFYACAERFGVDLAGGDTTRGPLTLSVTILGEVPRGQALTR
AGANAGDDIWVSGQPGLAALGLEMLRGTFAPTADGERCLAALHRPQPRVALGQALRGLASAALDISDGLLGDLGHILVQS
RCGATLHEDALPLAALYATGASPALARRCLLAGGDDYELLFCAPPAARAAITALGPALALPLTRIGTLSDAPGTVALRSA
DGTLTALAARGYDHFG

Sequences:

>Translated_336_residues
MPSSAPASRQNAPDAAATTAGEFALIQRHFSRPCGHTALAGGDDAALLHPRPGMELAVSADMLVAGTHFFPDADPHDLGW
KTLAVNVSDLAAMGADPRWALLSLALPAADDAWIAAFADGFYACAERFGVDLAGGDTTRGPLTLSVTILGEVPRGQALTR
AGANAGDDIWVSGQPGLAALGLEMLRGTFAPTADGERCLAALHRPQPRVALGQALRGLASAALDISDGLLGDLGHILVQS
RCGATLHEDALPLAALYATGASPALARRCLLAGGDDYELLFCAPPAARAAITALGPALALPLTRIGTLSDAPGTVALRSA
DGTLTALAARGYDHFG
>Mature_335_residues
PSSAPASRQNAPDAAATTAGEFALIQRHFSRPCGHTALAGGDDAALLHPRPGMELAVSADMLVAGTHFFPDADPHDLGWK
TLAVNVSDLAAMGADPRWALLSLALPAADDAWIAAFADGFYACAERFGVDLAGGDTTRGPLTLSVTILGEVPRGQALTRA
GANAGDDIWVSGQPGLAALGLEMLRGTFAPTADGERCLAALHRPQPRVALGQALRGLASAALDISDGLLGDLGHILVQSR
CGATLHEDALPLAALYATGASPALARRCLLAGGDDYELLFCAPPAARAAITALGPALALPLTRIGTLSDAPGTVALRSAD
GTLTALAARGYDHFG

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=321, Percent_Identity=46.417445482866, Blast_Score=256, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34187; Mature: 34056

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSAPASRQNAPDAAATTAGEFALIQRHFSRPCGHTALAGGDDAALLHPRPGMELAVSA
CCCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCCCCEECCCCCCEEECCCCCCEEEEEC
DMLVAGTHFFPDADPHDLGWKTLAVNVSDLAAMGADPRWALLSLALPAADDAWIAAFADG
CEEEECCCCCCCCCCCCCCCEEEEEEHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHH
FYACAERFGVDLAGGDTTRGPLTLSVTILGEVPRGQALTRAGANAGDDIWVSGQPGLAAL
HHHHHHHHCCEECCCCCCCCCEEEEEEEEECCCCCCHHHHCCCCCCCCEEECCCCCHHHH
GLEMLRGTFAPTADGERCLAALHRPQPRVALGQALRGLASAALDISDGLLGDLGHILVQS
HHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RCGATLHEDALPLAALYATGASPALARRCLLAGGDDYELLFCAPPAARAAITALGPALAL
HCCCCHHHCCCCHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHH
PLTRIGTLSDAPGTVALRSADGTLTALAARGYDHFG
HHHHHCCCCCCCCEEEEECCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
PSSAPASRQNAPDAAATTAGEFALIQRHFSRPCGHTALAGGDDAALLHPRPGMELAVSA
CCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCCCCEECCCCCCEEECCCCCCEEEEEC
DMLVAGTHFFPDADPHDLGWKTLAVNVSDLAAMGADPRWALLSLALPAADDAWIAAFADG
CEEEECCCCCCCCCCCCCCCEEEEEEHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHH
FYACAERFGVDLAGGDTTRGPLTLSVTILGEVPRGQALTRAGANAGDDIWVSGQPGLAAL
HHHHHHHHCCEECCCCCCCCCEEEEEEEEECCCCCCHHHHCCCCCCCCEEECCCCCHHHH
GLEMLRGTFAPTADGERCLAALHRPQPRVALGQALRGLASAALDISDGLLGDLGHILVQS
HHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RCGATLHEDALPLAALYATGASPALARRCLLAGGDDYELLFCAPPAARAAITALGPALAL
HCCCCHHHCCCCHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHH
PLTRIGTLSDAPGTVALRSADGTLTALAARGYDHFG
HHHHHCCCCCCCCEEEEECCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]