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The map label for this gene is hprK

Identifier: 119896792

GI number: 119896792

Start: 539453

End: 540394

Strand: Reverse

Name: hprK

Synonym: azo0501

Alternate gene names: 119896792

Gene position: 540394-539453 (Counterclockwise)

Preceding gene: 119896793

Following gene: 119896791

Centisome position: 12.35

GC content: 69.11

Gene sequence:

>942_bases
ATGCGGCAGACCAGCGTCGCGCGGCTGTATGAGGACCAGGGTCCCCGGCTGCAACTGACCCACGTCAGCGGGCCGCTCGA
CGCTGTCCTGTCCGTCGCTGAAGAACGCATGTGGCCGGCCGACCTCGTCGGCCACCTGAACCTGATCCATCCCACCCGCC
TGCAGGTGCTGGGCGCCGCCGAACTCGAATGGGCCCGGCGCCAGTCGCGCGAGAAGGTCGCGCACCACCTCAACGGCATC
CTGTCCGCGCGCCCGCCCGCCATCATCGTGGCCGACGGCTGCGAAACGCCCAACATCGTGCACGGCGTCTGCACCGCGCA
CAACGTGGCGCTGTTCTCCACGCCGCACCCCTCGGCCAGCGTGATCGACCAGTTGCGGCTCTACCTGTCGCGCCAGCTGG
CGGAAAAGATCTCGCTGCACGGCGTGTTCATGGACGTGCTCGGCATCGGCGTGTTCATTACCGGCAACTCCGGCGCCGGC
AAGTCCGAACTCGCGCTCGAGCTGATCTCGCGCGGCCACGGCCTGGTCGCGGACGACATCGTCGAGTTCTCCCGCACCGC
GCCCACGGTGCTCGAAGGACGCTGCCCGGAACTGCTGAAGGACTTCATCGAGGTCCGCGGACTCGGCATCCTCAACATCC
GCACGATCTTCGGCGAGACGGCCTGCCGGCGGAAGATGCGCCTGCGCCTGGTCTGCCATCTCGAACGCCGCCAGCCCGGC
CAGGATGACCCGAACCGCCTGCCGGTGCAGCAGGAGCAGCAGGTCATCCTGGGCGTCAGCACGCCGCGCGTCACCCTGCC
GGTGGCCGCAGGCCGCAACCTTGCGGTGCTGCTCGAAGCCGCGGTGCGGTCCACCATCCTGCAGCTGCGCGGCGTCGACT
CCACCCAGGAATTCATCGACCGCCAGAGCCGGATGCTGATGGGCGACGGCGACGGCCTCTGA

Upstream 100 bases:

>100_bases
GAACTCGCGCAGATGTTCAGCGAGCGCGCCTTCCGCGAACAGCTGCTGGTCGCCCCGGACGCCGCCACCATCCACGCGCT
GTTCGCCAACTGGGGGCCCG

Downstream 100 bases:

>100_bases
CCCTGGCGTCGCGCGGCGCACCCTCCCGCCAAGCCCGTCCCCTGCCTGGCAGCCGGCATCGCCCTTGCTGGGGTTGCGCC
CCGGCTGCTAACCTCGTCTC

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MRQTSVARLYEDQGPRLQLTHVSGPLDAVLSVAEERMWPADLVGHLNLIHPTRLQVLGAAELEWARRQSREKVAHHLNGI
LSARPPAIIVADGCETPNIVHGVCTAHNVALFSTPHPSASVIDQLRLYLSRQLAEKISLHGVFMDVLGIGVFITGNSGAG
KSELALELISRGHGLVADDIVEFSRTAPTVLEGRCPELLKDFIEVRGLGILNIRTIFGETACRRKMRLRLVCHLERRQPG
QDDPNRLPVQQEQQVILGVSTPRVTLPVAAGRNLAVLLEAAVRSTILQLRGVDSTQEFIDRQSRMLMGDGDGL

Sequences:

>Translated_313_residues
MRQTSVARLYEDQGPRLQLTHVSGPLDAVLSVAEERMWPADLVGHLNLIHPTRLQVLGAAELEWARRQSREKVAHHLNGI
LSARPPAIIVADGCETPNIVHGVCTAHNVALFSTPHPSASVIDQLRLYLSRQLAEKISLHGVFMDVLGIGVFITGNSGAG
KSELALELISRGHGLVADDIVEFSRTAPTVLEGRCPELLKDFIEVRGLGILNIRTIFGETACRRKMRLRLVCHLERRQPG
QDDPNRLPVQQEQQVILGVSTPRVTLPVAAGRNLAVLLEAAVRSTILQLRGVDSTQEFIDRQSRMLMGDGDGL
>Mature_313_residues
MRQTSVARLYEDQGPRLQLTHVSGPLDAVLSVAEERMWPADLVGHLNLIHPTRLQVLGAAELEWARRQSREKVAHHLNGI
LSARPPAIIVADGCETPNIVHGVCTAHNVALFSTPHPSASVIDQLRLYLSRQLAEKISLHGVFMDVLGIGVFITGNSGAG
KSELALELISRGHGLVADDIVEFSRTAPTVLEGRCPELLKDFIEVRGLGILNIRTIFGETACRRKMRLRLVCHLERRQPG
QDDPNRLPVQQEQQVILGVSTPRVTLPVAAGRNLAVLLEAAVRSTILQLRGVDSTQEFIDRQSRMLMGDGDGL

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPRK_AZOSB (A1K2R3)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_932005.1
- ProteinModelPortal:   A1K2R3
- SMR:   A1K2R3
- STRING:   A1K2R3
- GeneID:   4609068
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo0501
- eggNOG:   COG1493
- HOGENOM:   HBG566466
- OMA:   IHGVLVD
- ProtClustDB:   PRK05428
- BioCyc:   ASP62928:AZO0501-MONOMER
- HAMAP:   MF_01249
- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N

EC number: NA

Molecular weight: Translated: 34335; Mature: 34335

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: ACT_SITE 140-140 ACT_SITE 161-161 ACT_SITE 179-179 ACT_SITE 246-246

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQTSVARLYEDQGPRLQLTHVSGPLDAVLSVAEERMWPADLVGHLNLIHPTRLQVLGAA
CCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHCCHH
ELEWARRQSREKVAHHLNGILSARPPAIIVADGCETPNIVHGVCTAHNVALFSTPHPSAS
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCEEEEECCCCCHH
VIDQLRLYLSRQLAEKISLHGVFMDVLGIGVFITGNSGAGKSELALELISRGHGLVADDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHCCCCCHHHHH
VEFSRTAPTVLEGRCPELLKDFIEVRGLGILNIRTIFGETACRRKMRLRLVCHLERRQPG
HHHHCCCCHHHCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHEEEHHCCCC
QDDPNRLPVQQEQQVILGVSTPRVTLPVAAGRNLAVLLEAAVRSTILQLRGVDSTQEFID
CCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
RQSRMLMGDGDGL
HHHCEEECCCCCC
>Mature Secondary Structure
MRQTSVARLYEDQGPRLQLTHVSGPLDAVLSVAEERMWPADLVGHLNLIHPTRLQVLGAA
CCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHCCHH
ELEWARRQSREKVAHHLNGILSARPPAIIVADGCETPNIVHGVCTAHNVALFSTPHPSAS
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCEEEEECCCCCHH
VIDQLRLYLSRQLAEKISLHGVFMDVLGIGVFITGNSGAGKSELALELISRGHGLVADDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHCCCCCHHHHH
VEFSRTAPTVLEGRCPELLKDFIEVRGLGILNIRTIFGETACRRKMRLRLVCHLERRQPG
HHHHCCCCHHHCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHEEEHHCCCC
QDDPNRLPVQQEQQVILGVSTPRVTLPVAAGRNLAVLLEAAVRSTILQLRGVDSTQEFID
CCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
RQSRMLMGDGDGL
HHHCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA