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The map label for this gene is ubiA

Identifier: 119896770

GI number: 119896770

Start: 516019

End: 516882

Strand: Direct

Name: ubiA

Synonym: azo0479

Alternate gene names: 119896770

Gene position: 516019-516882 (Clockwise)

Preceding gene: 119896769

Following gene: 119896774

Centisome position: 11.79

GC content: 68.87

Gene sequence:

>864_bases
ATGACCCTCTCTGACCGTCTTCCCCTCTACGGCCGCCTGATGCGGCTGGACAAACCGATCGGCTCGCTGCTGCTGCTGTG
GCCCACGCTGTGGGCGCTGTGGCTGGCCGCCGACGGCAAGCCGCCGCTGCACGTGCTGGTGATCTTCACGATCGGCACCG
TGCTGATGCGTTCGGCTGGCTGCGTGATCAACGACTACGCCGACCGCGACTTCGACGGTCATGTCGAACGCACCCGCAAC
CGCCCGCTCGCCACCCGCGCGGTGAGCACGCGCGAGGCGCTGGCGCTGGCGGCGGGGCTGTCGGCGTTGTCCTTCGTGCT
GATCCTGCCGCTCGATCCGCTGGTGATCTGGCTGTCCTTTCCGGCGCTGTTCCTCGCCGCCAGCTATCCCTTCACCAAGC
GCTTCTTCGCGATCCCGCAGGCCTATCTCGGCATCGCCTTCGGCTTCGGCATCCCGATGGGTTTCGCCGCGGTGCAGGGC
GAGGTGCCGCCGATCGCGTGGGTGATGCTGCTCGCCAACATCTTCTGGGCGGTGGCCTACGACACCGAGTACGCGATGGT
GGACCGGCCCGACGACCTCAAGATCGGCATCAAGACCTCGGCGATCACCTTCGGCCGCTTCGACGTGGCGGCGGTGATGC
TGTGCTACGCGGTGGCGCTCGGCCTGCTCGGCTGGGTGGGGGCGCAGGCGGGGCGCGGCGCGCTCTACTTCGCGGGTCTG
GCGGTTGCGGCCGGCATGGCGCTGTACCACTACACGCTGATCCGCCACCGCGAACGGGCCCCGTGCTTCAAGGCCTTCCG
CCACAACAACTGGCTGGGCGCGGCGGTGTTCGCCGGGCTGGCGCTGGACTACCTGATCGGCTGA

Upstream 100 bases:

>100_bases
CTGCCGCCGGCACTGTGGGCGCGGCGCTCGGTGTTCCGCCTGCATGGCCGCTCACTGCTGGTGAGCGAGTTCTTCCTGCC
CGCGATACTCGGATTGCCCG

Downstream 100 bases:

>100_bases
TCCGCTCGCGCGGGCGCCGAAAAAGACATCGCCGGCGGCGGGGTGACCCGCGGCCGGCGATGTGCGTTTACATGGCCGCC
TGCGCGGCCTCCGGGGCTTA

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MTLSDRLPLYGRLMRLDKPIGSLLLLWPTLWALWLAADGKPPLHVLVIFTIGTVLMRSAGCVINDYADRDFDGHVERTRN
RPLATRAVSTREALALAAGLSALSFVLILPLDPLVIWLSFPALFLAASYPFTKRFFAIPQAYLGIAFGFGIPMGFAAVQG
EVPPIAWVMLLANIFWAVAYDTEYAMVDRPDDLKIGIKTSAITFGRFDVAAVMLCYAVALGLLGWVGAQAGRGALYFAGL
AVAAGMALYHYTLIRHRERAPCFKAFRHNNWLGAAVFAGLALDYLIG

Sequences:

>Translated_287_residues
MTLSDRLPLYGRLMRLDKPIGSLLLLWPTLWALWLAADGKPPLHVLVIFTIGTVLMRSAGCVINDYADRDFDGHVERTRN
RPLATRAVSTREALALAAGLSALSFVLILPLDPLVIWLSFPALFLAASYPFTKRFFAIPQAYLGIAFGFGIPMGFAAVQG
EVPPIAWVMLLANIFWAVAYDTEYAMVDRPDDLKIGIKTSAITFGRFDVAAVMLCYAVALGLLGWVGAQAGRGALYFAGL
AVAAGMALYHYTLIRHRERAPCFKAFRHNNWLGAAVFAGLALDYLIG
>Mature_286_residues
TLSDRLPLYGRLMRLDKPIGSLLLLWPTLWALWLAADGKPPLHVLVIFTIGTVLMRSAGCVINDYADRDFDGHVERTRNR
PLATRAVSTREALALAAGLSALSFVLILPLDPLVIWLSFPALFLAASYPFTKRFFAIPQAYLGIAFGFGIPMGFAAVQGE
VPPIAWVMLLANIFWAVAYDTEYAMVDRPDDLKIGIKTSAITFGRFDVAAVMLCYAVALGLLGWVGAQAGRGALYFAGLA
VAAGMALYHYTLIRHRERAPCFKAFRHNNWLGAAVFAGLALDYLIG

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family

Homologues:

Organism=Homo sapiens, GI260656052, Length=281, Percent_Identity=39.1459074733096, Blast_Score=171, Evalue=9e-43,
Organism=Escherichia coli, GI1790473, Length=281, Percent_Identity=53.7366548042705, Blast_Score=285, Evalue=3e-78,
Organism=Caenorhabditis elegans, GI17553718, Length=286, Percent_Identity=34.965034965035, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI32565247, Length=286, Percent_Identity=33.2167832167832, Blast_Score=137, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17553720, Length=342, Percent_Identity=29.5321637426901, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32565245, Length=137, Percent_Identity=44.5255474452555, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI32565243, Length=133, Percent_Identity=44.3609022556391, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324370, Length=293, Percent_Identity=32.0819112627986, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21355567, Length=280, Percent_Identity=35.7142857142857, Blast_Score=165, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIA_AZOSB (A1K2P1)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_931983.1
- STRING:   A1K2P1
- GeneID:   4610057
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo0479
- eggNOG:   COG0382
- HOGENOM:   HBG324383
- OMA:   YHYTLIR
- PhylomeDB:   A1K2P1
- ProtClustDB:   PRK12848
- BioCyc:   ASP62928:AZO0479-MONOMER
- HAMAP:   MF_01635
- InterPro:   IPR006370
- InterPro:   IPR000537
- TIGRFAMs:   TIGR01474

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 31396; Mature: 31265

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x18ae985c)-; HASH(0x19e756b0)-; HASH(0x199a5180)-; HASH(0x198f3f10)-; HASH(0x18645c10)-; HASH(0x18f4bc00)-; HASH(0x406b7c3c)-; HASH(0x186f99bc)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSDRLPLYGRLMRLDKPIGSLLLLWPTLWALWLAADGKPPLHVLVIFTIGTVLMRSAG
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCC
CVINDYADRDFDGHVERTRNRPLATRAVSTREALALAAGLSALSFVLILPLDPLVIWLSF
CEEECCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
PALFLAASYPFTKRFFAIPQAYLGIAFGFGIPMGFAAVQGEVPPIAWVMLLANIFWAVAY
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHC
DTEYAMVDRPDDLKIGIKTSAITFGRFDVAAVMLCYAVALGLLGWVGAQAGRGALYFAGL
CCCEEEECCCCCCEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AVAAGMALYHYTLIRHRERAPCFKAFRHNNWLGAAVFAGLALDYLIG
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
TLSDRLPLYGRLMRLDKPIGSLLLLWPTLWALWLAADGKPPLHVLVIFTIGTVLMRSAG
CCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCC
CVINDYADRDFDGHVERTRNRPLATRAVSTREALALAAGLSALSFVLILPLDPLVIWLSF
CEEECCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
PALFLAASYPFTKRFFAIPQAYLGIAFGFGIPMGFAAVQGEVPPIAWVMLLANIFWAVAY
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHC
DTEYAMVDRPDDLKIGIKTSAITFGRFDVAAVMLCYAVALGLLGWVGAQAGRGALYFAGL
CCCEEEECCCCCCEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AVAAGMALYHYTLIRHRERAPCFKAFRHNNWLGAAVFAGLALDYLIG
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA