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The map label for this gene is ubiC

Identifier: 119896769

GI number: 119896769

Start: 515463

End: 516032

Strand: Direct

Name: ubiC

Synonym: azo0478

Alternate gene names: 119896769

Gene position: 515463-516032 (Clockwise)

Preceding gene: 119896768

Following gene: 119896770

Centisome position: 11.78

GC content: 74.91

Gene sequence:

>570_bases
ATGCAGCACCCCGCTTCCGGCGAGTCCTGGCTCGCCCGCCCGCCGCGCACCGCCGAGCGCCGGCTGCGCCCCTGGCTGAC
CGATCCCGCCTCGCTCACCGCCCGTATCCGCATGCGCTGCGGCATGTTCGGGGTGCGGGTGCTGCGCCAATCGGCCGGCG
CTCTGACCCCGGACGAACGCCGTCTGCTCGGCCTGCGCGCCGGCGAGCGCGCACTGCTGCGCGAGGTGCTGCTGATCGCC
GACGGTCGCCCGGTGGTGTTTGCGCGCAGCGTGCTGGCGCAGCGCGAACAGCGCGGCGGCTGGCTGCGGTTGTGGCGCGG
CATCGGCAGCCGGCCGCTGGGCGCGGCGCTGTTTTCCGATCCGCGCATCCGCCGCCAACCGCTGGCCTGCGCCCGCATCG
GGGCCGCCGACGCGCGTTATCATCTCGCCCGACGCGCGCTCGCCGGCGCCGCGACGCTGCCGCCGGCACTGTGGGCGCGG
CGCTCGGTGTTCCGCCTGCATGGCCGCTCACTGCTGGTGAGCGAGTTCTTCCTGCCCGCGATACTCGGATTGCCCGATGA
CCCTCTCTGA

Upstream 100 bases:

>100_bases
GATGCAGCGCTGGCTCGGTGGGCGGGAGTCGCTGCTGCGCGCCTGATGGCCGAGCCGGTCGGCTAAGATCACGGCCTTGC
TCCGCTTTCCCGTGTCACCG

Downstream 100 bases:

>100_bases
CCGTCTTCCCCTCTACGGCCGCCTGATGCGGCTGGACAAACCGATCGGCTCGCTGCTGCTGCTGTGGCCCACGCTGTGGG
CGCTGTGGCTGGCCGCCGAC

Product: putative chorismate:pyruvate lyase

Products: NA

Alternate protein names: CL; CPL

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MQHPASGESWLARPPRTAERRLRPWLTDPASLTARIRMRCGMFGVRVLRQSAGALTPDERRLLGLRAGERALLREVLLIA
DGRPVVFARSVLAQREQRGGWLRLWRGIGSRPLGAALFSDPRIRRQPLACARIGAADARYHLARRALAGAATLPPALWAR
RSVFRLHGRSLLVSEFFLPAILGLPDDPL

Sequences:

>Translated_189_residues
MQHPASGESWLARPPRTAERRLRPWLTDPASLTARIRMRCGMFGVRVLRQSAGALTPDERRLLGLRAGERALLREVLLIA
DGRPVVFARSVLAQREQRGGWLRLWRGIGSRPLGAALFSDPRIRRQPLACARIGAADARYHLARRALAGAATLPPALWAR
RSVFRLHGRSLLVSEFFLPAILGLPDDPL
>Mature_189_residues
MQHPASGESWLARPPRTAERRLRPWLTDPASLTARIRMRCGMFGVRVLRQSAGALTPDERRLLGLRAGERALLREVLLIA
DGRPVVFARSVLAQREQRGGWLRLWRGIGSRPLGAALFSDPRIRRQPLACARIGAADARYHLARRALAGAATLPPALWAR
RSVFRLHGRSLLVSEFFLPAILGLPDDPL

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIC_AZOSB (A1K2P0)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_931982.1
- ProteinModelPortal:   A1K2P0
- STRING:   A1K2P0
- GeneID:   4609706
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo0478
- eggNOG:   NOG120169
- HOGENOM:   HBG644467
- OMA:   GTPYVAA
- ProtClustDB:   CLSK766526
- BioCyc:   ASP62928:AZO0478-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01632
- InterPro:   IPR007440

Pfam domain/function: PF04345 Chor_lyase

EC number: =4.1.3.40

Molecular weight: Translated: 21043; Mature: 21043

Theoretical pI: Translated: 12.42; Mature: 12.42

Prosite motif: NA

Important sites: BINDING 74-74 BINDING 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHPASGESWLARPPRTAERRLRPWLTDPASLTARIRMRCGMFGVRVLRQSAGALTPDER
CCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
RLLGLRAGERALLREVLLIADGRPVVFARSVLAQREQRGGWLRLWRGIGSRPLGAALFSD
HHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHCC
PRIRRQPLACARIGAADARYHLARRALAGAATLPPALWARRSVFRLHGRSLLVSEFFLPA
CCCHHCCCHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
ILGLPDDPL
HHCCCCCCC
>Mature Secondary Structure
MQHPASGESWLARPPRTAERRLRPWLTDPASLTARIRMRCGMFGVRVLRQSAGALTPDER
CCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
RLLGLRAGERALLREVLLIADGRPVVFARSVLAQREQRGGWLRLWRGIGSRPLGAALFSD
HHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHCC
PRIRRQPLACARIGAADARYHLARRALAGAATLPPALWARRSVFRLHGRSLLVSEFFLPA
CCCHHCCCHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
ILGLPDDPL
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA