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The map label for this gene is lig [H]

Identifier: 119896734

GI number: 119896734

Start: 468959

End: 470002

Strand: Direct

Name: lig [H]

Synonym: azo0443

Alternate gene names: 119896734

Gene position: 468959-470002 (Clockwise)

Preceding gene: 119896726

Following gene: 119896735

Centisome position: 10.72

GC content: 73.66

Gene sequence:

>1044_bases
ATGGATCTCATCGTCGCCCGCCCCGAAGGCCTGTACTGCCCGCCCGGGGATTTCTACATCGACCCCTGGCGTCCGGTGGA
TCGCGCCGTGATCACCCACGGCCATGGCGACCACGCCCGCCCCGGCCACCGTCATTACCTCGCTGCCGCGCCGGGCGAGG
GCGTGCTGCGCGCGCGCCTGGGCGAAATTCCGCTGCAGACGCTGGGTTATGGCGAGGAGGTCCGCCACCACGGCGTCGGC
ATCCGCTTCCACCCTGCGGGGCACGTGCTCGGCTCCGCCCAGGTGCGGATCGAATACCGGGGCGAAGTCTGGGTGGCCTC
CGGCGACTACAAGCTGGAAGCGGACGGCACCTGCGACGCGTTCGAGCCGGTGCGCTGCGACACCTTCATCACCGAATCCA
CCTTCGGCCTGCCGATCTACCGCTGGCCGCCGCAGGCCGAGCTGGGCGCGGCGATCAATGCCTGGTGGCAGGCCAATGCC
GCGGCCGGGCGCGCTTCGGTGCTGTTCTGCTACGCCTTCGGCAAGGCCCAGCGCATCCTGCATCTGCTCGACCCCGCCAT
CGGTCCCATCGTCGTGCACGGCGCGGTGGAGCCGCTCAACGCGGTGTACCGCGCCGCGGGCGTCGCGCTGCCGGCCACGC
GCAAGGTCGGCGAGGTGGCGGCGGAGGAGCTGCGGCGCGCCCTGGTGCTGGCGCCGCCCTCGGCCCAGGGCAGCCCGTGG
CTGCGCCGTTTCGGCGACTACGCCGATGCCTTCGCCAGCGGCTGGATGCGCATTCGCGGCACGCGCCGCCGGCGCGGGGT
GGACCGCGGCTTCGTGCTGTCGGACCACGCCGACTGGCCCGGCCTGCTGCGCGCGATCGAGGCCACCGGCGCGCAGCGGG
TGTTCGTCACCCACGGCAGCGTCGCGGTGCTGGTGCGCTGGCTGGGCGAGCAGGGGCTGGCGGCGCAGGCCTTCGCCACC
GAATACGGCGAGGAGGACGACGCCGGCCAGGGCGGCGCGGGCGATTCCGCGCGCCCGGACGATGCGGCGGAGCCCCCGCA
ATGA

Upstream 100 bases:

>100_bases
GTGCGGGAACACCGCCGGCGCCGCGGCGGTCCCTTGTGCAGCGCCGGCGGCGGGAGCCAAGCCCGGCCGGCGCGCCCCGT
CCGTCACGCCGCTGGAGCAC

Downstream 100 bases:

>100_bases
AGGCCTTTGCCGCCCTCTACGCCGAACTCGACGCCACCACTTCCAGCAATGCCAAGCTCGCCGCGATGGTGGCGTACTTC
CGCGCCGCGCCGGCGGCGGA

Product: beta-lactamase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MDLIVARPEGLYCPPGDFYIDPWRPVDRAVITHGHGDHARPGHRHYLAAAPGEGVLRARLGEIPLQTLGYGEEVRHHGVG
IRFHPAGHVLGSAQVRIEYRGEVWVASGDYKLEADGTCDAFEPVRCDTFITESTFGLPIYRWPPQAELGAAINAWWQANA
AAGRASVLFCYAFGKAQRILHLLDPAIGPIVVHGAVEPLNAVYRAAGVALPATRKVGEVAAEELRRALVLAPPSAQGSPW
LRRFGDYADAFASGWMRIRGTRRRRGVDRGFVLSDHADWPGLLRAIEATGAQRVFVTHGSVAVLVRWLGEQGLAAQAFAT
EYGEEDDAGQGGAGDSARPDDAAEPPQ

Sequences:

>Translated_347_residues
MDLIVARPEGLYCPPGDFYIDPWRPVDRAVITHGHGDHARPGHRHYLAAAPGEGVLRARLGEIPLQTLGYGEEVRHHGVG
IRFHPAGHVLGSAQVRIEYRGEVWVASGDYKLEADGTCDAFEPVRCDTFITESTFGLPIYRWPPQAELGAAINAWWQANA
AAGRASVLFCYAFGKAQRILHLLDPAIGPIVVHGAVEPLNAVYRAAGVALPATRKVGEVAAEELRRALVLAPPSAQGSPW
LRRFGDYADAFASGWMRIRGTRRRRGVDRGFVLSDHADWPGLLRAIEATGAQRVFVTHGSVAVLVRWLGEQGLAAQAFAT
EYGEEDDAGQGGAGDSARPDDAAEPPQ
>Mature_347_residues
MDLIVARPEGLYCPPGDFYIDPWRPVDRAVITHGHGDHARPGHRHYLAAAPGEGVLRARLGEIPLQTLGYGEEVRHHGVG
IRFHPAGHVLGSAQVRIEYRGEVWVASGDYKLEADGTCDAFEPVRCDTFITESTFGLPIYRWPPQAELGAAINAWWQANA
AAGRASVLFCYAFGKAQRILHLLDPAIGPIVVHGAVEPLNAVYRAAGVALPATRKVGEVAAEELRRALVLAPPSAQGSPW
LRRFGDYADAFASGWMRIRGTRRRRGVDRGFVLSDHADWPGLLRAIEATGAQRVFVTHGSVAVLVRWLGEQGLAAQAFAT
EYGEEDDAGQGGAGDSARPDDAAEPPQ

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011108 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N; PF07521 RMMBL [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 37526; Mature: 37526

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLIVARPEGLYCPPGDFYIDPWRPVDRAVITHGHGDHARPGHRHYLAAAPGEGVLRARL
CCEEEECCCCCCCCCCCEEECCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCCHHHHHH
GEIPLQTLGYGEEVRHHGVGIRFHPAGHVLGSAQVRIEYRGEVWVASGDYKLEADGTCDA
CCCCHHHCCCCHHHHHCCCCEEECCCCCEECCEEEEEEECCEEEEECCCEEEECCCCCCC
FEPVRCDTFITESTFGLPIYRWPPQAELGAAINAWWQANAAAGRASVLFCYAFGKAQRIL
CCCCCCCEEEECCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHHH
HLLDPAIGPIVVHGAVEPLNAVYRAAGVALPATRKVGEVAAEELRRALVLAPPSAQGSPW
HHHCCCCCCEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCCHH
LRRFGDYADAFASGWMRIRGTRRRRGVDRGFVLSDHADWPGLLRAIEATGAQRVFVTHGS
HHHHHHHHHHHHHCCEEEECCHHHCCCCCCEEEECCCCCHHHHHHHHHCCCEEEEEECCC
VAVLVRWLGEQGLAAQAFATEYGEEDDAGQGGAGDSARPDDAAEPPQ
HHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDLIVARPEGLYCPPGDFYIDPWRPVDRAVITHGHGDHARPGHRHYLAAAPGEGVLRARL
CCEEEECCCCCCCCCCCEEECCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCCHHHHHH
GEIPLQTLGYGEEVRHHGVGIRFHPAGHVLGSAQVRIEYRGEVWVASGDYKLEADGTCDA
CCCCHHHCCCCHHHHHCCCCEEECCCCCEECCEEEEEEECCEEEEECCCEEEECCCCCCC
FEPVRCDTFITESTFGLPIYRWPPQAELGAAINAWWQANAAAGRASVLFCYAFGKAQRIL
CCCCCCCEEEECCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHHH
HLLDPAIGPIVVHGAVEPLNAVYRAAGVALPATRKVGEVAAEELRRALVLAPPSAQGSPW
HHHCCCCCCEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCCHH
LRRFGDYADAFASGWMRIRGTRRRRGVDRGFVLSDHADWPGLLRAIEATGAQRVFVTHGS
HHHHHHHHHHHHHCCEEEECCHHHCCCCCCEEEECCCCCHHHHHHHHHCCCEEEEEECCC
VAVLVRWLGEQGLAAQAFATEYGEEDDAGQGGAGDSARPDDAAEPPQ
HHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA