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The map label for this gene is hslV

Identifier: 119896714

GI number: 119896714

Start: 447262

End: 447798

Strand: Direct

Name: hslV

Synonym: azo0423

Alternate gene names: 119896714

Gene position: 447262-447798 (Clockwise)

Preceding gene: 119896713

Following gene: 119896715

Centisome position: 10.22

GC content: 67.23

Gene sequence:

>537_bases
ATGGAACAGTATCACGGCACCACCATCCTTTCGGTGCGCCGCGGCAACAGCGTCGCGCTCGGTGGCGACGGGCAGGTCAC
GCTCGGCAACATCGTCGTCAAGGCGTCGGCGCGCAAGGTGCGCACGCTCTACCAGGGCCAGATCCTGGCCGGCTTCGCGG
GCGGTACGGCCGATGCCTTCACGCTGTTCGAACGCTTCGAGGCCAAGCTCGACAAGCACCAGGGCAACCTGCTGCGCAGC
GCGGTGGAACTCGCCAAGGACTGGCGCACCGACCGCATGCTGCGCCGGCTCGAAGCCATGCTGGCGGTGGCCGACCGCGA
GCACTCGCTGATCATCACCGGCAATGGCGACGTGCTGGAGCCCGAGCAGGGCATCGTCGCCATCGGTAGCGGCGGGGCCT
ATGCCCAGTCGGCCGCGCGGGCGTTGATCGAAAACACCGAACTGTCGCCGCGCGACGTGATCGCCAAGTCGCTCGCCATC
GCCGGCGACCTCTGCATCTACACCAACCAGTGCCACACGATCGAAGTGCTGGACTGA

Upstream 100 bases:

>100_bases
GCGATGGTCGGCGCGCTGCTGCGCGTCATGAGCGTGGATCAGGTCGCGCAGGTCACCCTGCGCGCATAAGGCTGCGGCCT
CTTCCTTGCGGGAATCGGAC

Downstream 100 bases:

>100_bases
GCGCGCCGTCGTAACCCGTTTCGAGCGAACCGCCATGACCCAGATGACCCCGCCGGAGATCGTCTCCGAACTCGACAAGC
ACATCGTCGGCCAGGCCCGC

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MEQYHGTTILSVRRGNSVALGGDGQVTLGNIVVKASARKVRTLYQGQILAGFAGGTADAFTLFERFEAKLDKHQGNLLRS
AVELAKDWRTDRMLRRLEAMLAVADREHSLIITGNGDVLEPEQGIVAIGSGGAYAQSAARALIENTELSPRDVIAKSLAI
AGDLCIYTNQCHTIEVLD

Sequences:

>Translated_178_residues
MEQYHGTTILSVRRGNSVALGGDGQVTLGNIVVKASARKVRTLYQGQILAGFAGGTADAFTLFERFEAKLDKHQGNLLRS
AVELAKDWRTDRMLRRLEAMLAVADREHSLIITGNGDVLEPEQGIVAIGSGGAYAQSAARALIENTELSPRDVIAKSLAI
AGDLCIYTNQCHTIEVLD
>Mature_178_residues
MEQYHGTTILSVRRGNSVALGGDGQVTLGNIVVKASARKVRTLYQGQILAGFAGGTADAFTLFERFEAKLDKHQGNLLRS
AVELAKDWRTDRMLRRLEAMLAVADREHSLIITGNGDVLEPEQGIVAIGSGGAYAQSAARALIENTELSPRDVIAKSLAI
AGDLCIYTNQCHTIEVLD

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=171, Percent_Identity=69.0058479532164, Blast_Score=248, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_AZOSB (A1K2I5)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_931927.1
- ProteinModelPortal:   A1K2I5
- SMR:   A1K2I5
- STRING:   A1K2I5
- MEROPS:   T01.006
- GeneID:   4606395
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo0423
- eggNOG:   COG5405
- HOGENOM:   HBG288822
- OMA:   AADICVY
- PhylomeDB:   A1K2I5
- ProtClustDB:   PRK05456
- BioCyc:   ASP62928:AZO0423-MONOMER
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 19166; Mature: 19166

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: ACT_SITE 7-7

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQYHGTTILSVRRGNSVALGGDGQVTLGNIVVKASARKVRTLYQGQILAGFAGGTADAF
CCCCCCCEEEEEECCCEEEECCCCCEEEEEEEEEECHHHHHHHHCCEEEEEECCCCHHHH
TLFERFEAKLDKHQGNLLRSAVELAKDWRTDRMLRRLEAMLAVADREHSLIITGNGDVLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEC
PEQGIVAIGSGGAYAQSAARALIENTELSPRDVIAKSLAIAGDLCIYTNQCHTIEVLD
CCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEECCCCEEEEEC
>Mature Secondary Structure
MEQYHGTTILSVRRGNSVALGGDGQVTLGNIVVKASARKVRTLYQGQILAGFAGGTADAF
CCCCCCCEEEEEECCCEEEECCCCCEEEEEEEEEECHHHHHHHHCCEEEEEECCCCHHHH
TLFERFEAKLDKHQGNLLRSAVELAKDWRTDRMLRRLEAMLAVADREHSLIITGNGDVLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEC
PEQGIVAIGSGGAYAQSAARALIENTELSPRDVIAKSLAIAGDLCIYTNQCHTIEVLD
CCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA