Click here to switch to the map view.

The map label for this gene is add [H]

Identifier: 119896527

GI number: 119896527

Start: 261880

End: 262902

Strand: Reverse

Name: add [H]

Synonym: azo0236

Alternate gene names: 119896527

Gene position: 262902-261880 (Counterclockwise)

Preceding gene: 119896528

Following gene: 119896505

Centisome position: 6.01

GC content: 67.94

Gene sequence:

>1023_bases
ATGGATCCTTCCCGTCTCACCGACCTGCACGCCTACATCCGCGCCTTGCCCAAGGCCGAACTCCACCTGCACATCGAAGG
CACCCTGGAACCCGAACTGATGTTCGCACTCGCCGCGCGCAACGGCGTCGCGCTGCCCTGGGACAGCGTCGAGGCCACCC
GCGCCGCCTATGCCTTCAGCGACCTGCAGAGTTTTCTCGATCTCTACTACGCAGGCGCCGCCGCGCTGATCCACGAGCAG
GATTTCCACGACCTCGCGCTCGCCTATTTCGAGCGCGCCCATGAGGATGGCGTGGTCCATGCGGAACTCTTCTTCGACCC
GCAAACCCACACCGCGCGCGGCGTCGCCTTCGACACCGTGCTCGACGGGCTGGAACGCGCCTGCATCGAGGCGCAGGAGC
GCTGGGGCATCAGCTCGCGGCTGATCCTGTGCTTCCTGCGCCACCTGTCGGAAGAGGACGGCTTCGCGACGCTGGAGCAG
GCGCTGCCCCACCTCGCCCGCATCCACGGCGTCGGCCTGGATTCGTCGGAAAAGGGCCATCCGCCGGCCAAGTTCGCGCG
CCTGTTCGCGCGCTGCCGCGAACTCGGCCTGCACATCGTCGCCCACGCAGGCGAGGAAGGGCCGCCGGCCTACATCGAGG
AGGCGCTCGACATCCTGCAGGTGGAGCGCATCGACCACGGCGTGCGCGCCGCGGAAAGCGCGGCGCTGATGGAACGCCTC
GCGCGCGAGCAAGTGCCGCTCACGGTGTGCCCGCTGTCCAACGTCAAGCTGTGCGTGTTCGAGCGCCTGCAGGACCACAA
CCTCAAGCAGCTGCTGGACGCGGGGCTGAAGGTGACGATCAATTCCGACGATCCGGCGTATTTCGGCGGCTACGTCGGGC
AGAACTACCAGCAGACCGCGGAGGCGCTGGGTCTCAGCCGCACCGAACTGAAGCAGCTGGCGAAGAACAGCCTGGAGGCG
AGCTTCGTGCCGCAGGCGGTGCTGGACCCGTGGCTGCTGCGGCTGGCGGCGGTGCCGGACTGA

Upstream 100 bases:

>100_bases
CCGCGGCAGCCGGCCTCGTCGGCGCATAATGGCAGGCCGCGCGCGGGGCGCCAGCGCGCGGCCAAGACGATCTTCCCCCT
GACCGGACACGGAGGTGGCA

Downstream 100 bases:

>100_bases
GTGCCGCCCCGGACCGGGGTGAACCCCATCCCCACCCCAACCCTCCCCTTGAAGGGGAGGGAGTAAACAGGCCAACCCGG
GAGCCTCCGCTACGCTCCGT

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MDPSRLTDLHAYIRALPKAELHLHIEGTLEPELMFALAARNGVALPWDSVEATRAAYAFSDLQSFLDLYYAGAAALIHEQ
DFHDLALAYFERAHEDGVVHAELFFDPQTHTARGVAFDTVLDGLERACIEAQERWGISSRLILCFLRHLSEEDGFATLEQ
ALPHLARIHGVGLDSSEKGHPPAKFARLFARCRELGLHIVAHAGEEGPPAYIEEALDILQVERIDHGVRAAESAALMERL
AREQVPLTVCPLSNVKLCVFERLQDHNLKQLLDAGLKVTINSDDPAYFGGYVGQNYQQTAEALGLSRTELKQLAKNSLEA
SFVPQAVLDPWLLRLAAVPD

Sequences:

>Translated_340_residues
MDPSRLTDLHAYIRALPKAELHLHIEGTLEPELMFALAARNGVALPWDSVEATRAAYAFSDLQSFLDLYYAGAAALIHEQ
DFHDLALAYFERAHEDGVVHAELFFDPQTHTARGVAFDTVLDGLERACIEAQERWGISSRLILCFLRHLSEEDGFATLEQ
ALPHLARIHGVGLDSSEKGHPPAKFARLFARCRELGLHIVAHAGEEGPPAYIEEALDILQVERIDHGVRAAESAALMERL
AREQVPLTVCPLSNVKLCVFERLQDHNLKQLLDAGLKVTINSDDPAYFGGYVGQNYQQTAEALGLSRTELKQLAKNSLEA
SFVPQAVLDPWLLRLAAVPD
>Mature_340_residues
MDPSRLTDLHAYIRALPKAELHLHIEGTLEPELMFALAARNGVALPWDSVEATRAAYAFSDLQSFLDLYYAGAAALIHEQ
DFHDLALAYFERAHEDGVVHAELFFDPQTHTARGVAFDTVLDGLERACIEAQERWGISSRLILCFLRHLSEEDGFATLEQ
ALPHLARIHGVGLDSSEKGHPPAKFARLFARCRELGLHIVAHAGEEGPPAYIEEALDILQVERIDHGVRAAESAALMERL
AREQVPLTVCPLSNVKLCVFERLQDHNLKQLLDAGLKVTINSDDPAYFGGYVGQNYQQTAEALGLSRTELKQLAKNSLEA
SFVPQAVLDPWLLRLAAVPD

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=331, Percent_Identity=25.9818731117825, Blast_Score=125, Evalue=6e-29,
Organism=Escherichia coli, GI1787910, Length=318, Percent_Identity=32.3899371069182, Blast_Score=147, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17538512, Length=349, Percent_Identity=22.9226361031519, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32565969, Length=336, Percent_Identity=22.9166666666667, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324188, Length=336, Percent_Identity=45.2380952380952, Blast_Score=300, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24645260, Length=331, Percent_Identity=23.2628398791541, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 37655; Mature: 37655

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPSRLTDLHAYIRALPKAELHLHIEGTLEPELMFALAARNGVALPWDSVEATRAAYAFS
CCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
DLQSFLDLYYAGAAALIHEQDFHDLALAYFERAHEDGVVHAELFFDPQTHTARGVAFDTV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHH
LDGLERACIEAQERWGISSRLILCFLRHLSEEDGFATLEQALPHLARIHGVGLDSSEKGH
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
PPAKFARLFARCRELGLHIVAHAGEEGPPAYIEEALDILQVERIDHGVRAAESAALMERL
CHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AREQVPLTVCPLSNVKLCVFERLQDHNLKQLLDAGLKVTINSDDPAYFGGYVGQNYQQTA
HHHCCCEEEECCCCCHHHHHHHHHCCCHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHH
EALGLSRTELKQLAKNSLEASFVPQAVLDPWLLRLAAVPD
HHHCCCHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDPSRLTDLHAYIRALPKAELHLHIEGTLEPELMFALAARNGVALPWDSVEATRAAYAFS
CCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
DLQSFLDLYYAGAAALIHEQDFHDLALAYFERAHEDGVVHAELFFDPQTHTARGVAFDTV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHH
LDGLERACIEAQERWGISSRLILCFLRHLSEEDGFATLEQALPHLARIHGVGLDSSEKGH
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
PPAKFARLFARCRELGLHIVAHAGEEGPPAYIEEALDILQVERIDHGVRAAESAALMERL
CHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AREQVPLTVCPLSNVKLCVFERLQDHNLKQLLDAGLKVTINSDDPAYFGGYVGQNYQQTA
HHHCCCEEEECCCCCHHHHHHHHHCCCHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHH
EALGLSRTELKQLAKNSLEASFVPQAVLDPWLLRLAAVPD
HHHCCCHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA