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The map label for this gene is helX [H]

Identifier: 119896394

GI number: 119896394

Start: 120960

End: 121487

Strand: Direct

Name: helX [H]

Synonym: azo0102

Alternate gene names: 119896394

Gene position: 120960-121487 (Clockwise)

Preceding gene: 119896393

Following gene: 119896395

Centisome position: 2.76

GC content: 70.45

Gene sequence:

>528_bases
ATGACCAGCCGCCGCCTGCTGCGGCGTTTCTTCTGCGCGCTTGCCGTGTGCCTCGCACCGGCAAGCGCGTTTGCCGTCGA
CCTCGAGCCGCTTGCCACGCTGCCGCCCGCGCCCGCGGCGCTGCAGGCAGAACTGGCGCGCGTGCAGGGGCGTGCGGTGC
TGATCAACTTCTGGGCGAGCTGGTGCGAGCCCTGCCGCGACGAGATGCCTGCGCTGGTCGAGCTGGACGAGCAGGAGCCG
GGGATCGCGCTGATCACCGTCGCGGTGGCCGATCGCGCCGCCGACAGCCGGCGCTTTCTCGACGACTACCTGCTCGACAA
CGTCGTGCTGATCAACGACCCCGAACAACTGATCGCCCGTGCCTGGGGTGCGCGCCTGCTGCCCACCACCATCATGCTCG
ACGCCGCCCATCGCCCGCGTTTTCGCGTGCGCGGTGAGGCCGACTGGCGCGCGCCCGAGCTGCGCGCCCGGCTGCGTGCG
CTGACCGCTTCCGAATCCACCCCTATCCCGAAAGGAAAGACACCGTGA

Upstream 100 bases:

>100_bases
CCGCTGTCCGGCGGCAGCCTGCGCGGGCTGTTCTCCACCCACCCCTCCACCGAGGAGCGCATCGCCCGCCTGCGCGCGAT
GGGGTGACGGGAATGGGGGC

Downstream 100 bases:

>100_bases
AACGCCGCGACTTCCTCAAGACCTCCGCGCTCGCCGCCGGCCTGGCACTGCCGGCCTGGGCGCGCGCTGCCGATACCGCC
GCGCCGCTGTTCGCGCCCTC

Product: putative thiol:disulphide oxidoreductase

Products: NA

Alternate protein names: Cytochrome c biogenesis protein helX [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MTSRRLLRRFFCALAVCLAPASAFAVDLEPLATLPPAPAALQAELARVQGRAVLINFWASWCEPCRDEMPALVELDEQEP
GIALITVAVADRAADSRRFLDDYLLDNVVLINDPEQLIARAWGARLLPTTIMLDAAHRPRFRVRGEADWRAPELRARLRA
LTASESTPIPKGKTP

Sequences:

>Translated_175_residues
MTSRRLLRRFFCALAVCLAPASAFAVDLEPLATLPPAPAALQAELARVQGRAVLINFWASWCEPCRDEMPALVELDEQEP
GIALITVAVADRAADSRRFLDDYLLDNVVLINDPEQLIARAWGARLLPTTIMLDAAHRPRFRVRGEADWRAPELRARLRA
LTASESTPIPKGKTP
>Mature_174_residues
TSRRLLRRFFCALAVCLAPASAFAVDLEPLATLPPAPAALQAELARVQGRAVLINFWASWCEPCRDEMPALVELDEQEPG
IALITVAVADRAADSRRFLDDYLLDNVVLINDPEQLIARAWGARLLPTTIMLDAAHRPRFRVRGEADWRAPELRARLRAL
TASESTPIPKGKTP

Specific function: Required for disulfide bond formation in some periplasmic proteins. Also act as a disulfide oxidoreductase in cytochromes c biogenesis. The cysteines of apocytochromes c must be in the reduced state for covalent linkage between the two moieties to occur [

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 19379; Mature: 19247

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRRLLRRFFCALAVCLAPASAFAVDLEPLATLPPAPAALQAELARVQGRAVLINFWAS
CCHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHH
WCEPCRDEMPALVELDEQEPGIALITVAVADRAADSRRFLDDYLLDNVVLINDPEQLIAR
HHHHHHHCCCCEEEECCCCCCEEEEEEEHHHHCCHHHHHHHHHHHCCEEEECCHHHHHHH
AWGARLLPTTIMLDAAHRPRFRVRGEADWRAPELRARLRALTASESTPIPKGKTP
HHCCHHCCHHHEEECCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TSRRLLRRFFCALAVCLAPASAFAVDLEPLATLPPAPAALQAELARVQGRAVLINFWAS
CHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHH
WCEPCRDEMPALVELDEQEPGIALITVAVADRAADSRRFLDDYLLDNVVLINDPEQLIAR
HHHHHHHCCCCEEEECCCCCCEEEEEEEHHHHCCHHHHHHHHHHHCCEEEECCHHHHHHH
AWGARLLPTTIMLDAAHRPRFRVRGEADWRAPELRARLRALTASESTPIPKGKTP
HHCCHHCCHHHEEECCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8384715 [H]