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The map label for this gene is htpX [H]

Identifier: 119896393

GI number: 119896393

Start: 120104

End: 120946

Strand: Direct

Name: htpX [H]

Synonym: azo0101

Alternate gene names: 119896393

Gene position: 120104-120946 (Clockwise)

Preceding gene: 119896392

Following gene: 119896394

Centisome position: 2.74

GC content: 67.02

Gene sequence:

>843_bases
ATGTTCGGTAACTGGATCAAGACTTCGATACTCATGGCCGGCATCGTCGCGCTGTTCGGCGCGGTCGGCGGCGTCATCGG
CGGCAAGCAGGGCATGCTGCTGGCGCTGGTGCTGGGTGGCGCGATGAACCTGTGGGCCTACTGGTTCTCCGACAAGATGG
TGTTGAAGATGTACAACGCGCGCGAGGTCGACGAGGCCACCTCGCCCTATCTGTACAACATGGTGCGCGGCCTCGCCCAG
CGCGCCGGGCTGCCGATGCCCAAGGTCTACATCATTGACGAGGACCAGCCCAACGCCTTCGCCACCGGGCGCAATCCCGA
GCATGCCGCGGTAGCGGCCACCACCGGCATCATGCGGATGCTGTCCGAGCGCGAGCTGCGCGGCGTGATGGCGCACGAGC
TGGCGCACGTGAAGAACCGCGACATCCTGATCTCCACGATCTCGGCCACCGTCGCCGGGGCGATTTCGTCGCTCGCGCAG
TTCGGCATGTTCTTTGGCGGCTCGCGCGATGGCGAGGACCGGCCCAACCCGGTTGTCTCCATCATCGTCATGATCCTCGC
GCCGATCGCCGGCATGCTGATCCAGATGGCGATCAGCCGCACCCGCGAATTCGGAGCCGACCGTGGTGGCGCCGAGATCT
CCGGCGATCCGCAGGCGCTCGCCAGCGCGCTCGCGAAGATCGACGCCTACGCGCGCGGCATCCCGATGCACACCGCCGAG
GCCCATCCGGAAACCGCGCAGATGATGATCATGAATCCGCTGTCCGGCGGCAGCCTGCGCGGGCTGTTCTCCACCCACCC
CTCCACCGAGGAGCGCATCGCCCGCCTGCGCGCGATGGGGTGA

Upstream 100 bases:

>100_bases
CCGGGGAACGGTTCGCGGTTGGCGGAGCGCAAGCCGGTTGAAAGCGGGGCCGTCGGCCCCATCTACCGCCGCAAGGAATC
AGCTAGCAAGGATCACCCCC

Downstream 100 bases:

>100_bases
CGGGAATGGGGGCATGACCAGCCGCCGCCTGCTGCGGCGTTTCTTCTGCGCGCTTGCCGTGTGCCTCGCACCGGCAAGCG
CGTTTGCCGTCGACCTCGAG

Product: M48 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MFGNWIKTSILMAGIVALFGAVGGVIGGKQGMLLALVLGGAMNLWAYWFSDKMVLKMYNAREVDEATSPYLYNMVRGLAQ
RAGLPMPKVYIIDEDQPNAFATGRNPEHAAVAATTGIMRMLSERELRGVMAHELAHVKNRDILISTISATVAGAISSLAQ
FGMFFGGSRDGEDRPNPVVSIIVMILAPIAGMLIQMAISRTREFGADRGGAEISGDPQALASALAKIDAYARGIPMHTAE
AHPETAQMMIMNPLSGGSLRGLFSTHPSTEERIARLRAMG

Sequences:

>Translated_280_residues
MFGNWIKTSILMAGIVALFGAVGGVIGGKQGMLLALVLGGAMNLWAYWFSDKMVLKMYNAREVDEATSPYLYNMVRGLAQ
RAGLPMPKVYIIDEDQPNAFATGRNPEHAAVAATTGIMRMLSERELRGVMAHELAHVKNRDILISTISATVAGAISSLAQ
FGMFFGGSRDGEDRPNPVVSIIVMILAPIAGMLIQMAISRTREFGADRGGAEISGDPQALASALAKIDAYARGIPMHTAE
AHPETAQMMIMNPLSGGSLRGLFSTHPSTEERIARLRAMG
>Mature_280_residues
MFGNWIKTSILMAGIVALFGAVGGVIGGKQGMLLALVLGGAMNLWAYWFSDKMVLKMYNAREVDEATSPYLYNMVRGLAQ
RAGLPMPKVYIIDEDQPNAFATGRNPEHAAVAATTGIMRMLSERELRGVMAHELAHVKNRDILISTISATVAGAISSLAQ
FGMFFGGSRDGEDRPNPVVSIIVMILAPIAGMLIQMAISRTREFGADRGGAEISGDPQALASALAKIDAYARGIPMHTAE
AHPETAQMMIMNPLSGGSLRGLFSTHPSTEERIARLRAMG

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=283, Percent_Identity=32.1554770318021, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 29979; Mature: 29979

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGNWIKTSILMAGIVALFGAVGGVIGGKQGMLLALVLGGAMNLWAYWFSDKMVLKMYNA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
REVDEATSPYLYNMVRGLAQRAGLPMPKVYIIDEDQPNAFATGRNPEHAAVAATTGIMRM
HHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCHHHHHHHHHHHHH
LSERELRGVMAHELAHVKNRDILISTISATVAGAISSLAQFGMFFGGSRDGEDRPNPVVS
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
IIVMILAPIAGMLIQMAISRTREFGADRGGAEISGDPQALASALAKIDAYARGIPMHTAE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
AHPETAQMMIMNPLSGGSLRGLFSTHPSTEERIARLRAMG
CCCCHHHEEEECCCCCCCCCCHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MFGNWIKTSILMAGIVALFGAVGGVIGGKQGMLLALVLGGAMNLWAYWFSDKMVLKMYNA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
REVDEATSPYLYNMVRGLAQRAGLPMPKVYIIDEDQPNAFATGRNPEHAAVAATTGIMRM
HHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCHHHHHHHHHHHHH
LSERELRGVMAHELAHVKNRDILISTISATVAGAISSLAQFGMFFGGSRDGEDRPNPVVS
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
IIVMILAPIAGMLIQMAISRTREFGADRGGAEISGDPQALASALAKIDAYARGIPMHTAE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
AHPETAQMMIMNPLSGGSLRGLFSTHPSTEERIARLRAMG
CCCCHHHEEEECCCCCCCCCCHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA