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The map label for this gene is irgA1 [H]

Identifier: 119896385

GI number: 119896385

Start: 109778

End: 111763

Strand: Reverse

Name: irgA1 [H]

Synonym: azo0093

Alternate gene names: 119896385

Gene position: 111763-109778 (Counterclockwise)

Preceding gene: 119896387

Following gene: 119896384

Centisome position: 2.55

GC content: 69.28

Gene sequence:

>1986_bases
ATGTCGGCGCATGCCGAAGAGGGCTACTTCGAAACCCTGCCGGTCGTGCTCAGCGTGTCCAGGCTGCCCCAGGCCATGGA
AGACACGCCCGGCGCCGTCACGGTCATCGACAGCGAACTGATCGCCGCCACCGGTTACCGCGACCTCGCGCGCCTGTTCC
GGCTCGTTCCGGGCATGCAGGTCGGGCAGGAGCGCGCCAACCATCACTGGGTCACCTACCACGGGCTGGGGTCCGACTAT
CCCAACCAGATGCAGGTGCTGGTCGATGGCCGCTCGGTGTATTCGCCCTACTTCTTCGGCGGTGCGGATTGGGGGTCGCT
GCCAATCGCGCTCGAAGACATCGACCGCATCGAGGTCGTGCGCGGCTCGGATTCGGCCGCCTACGGCTCCAACGCCTTCC
TCGGCGTGGTCAATATCCTCACCCGCCACACCGGGGCCGAAACCGGCAACTCGGTGTCGTTGCGCGGCGGCACCAACGGC
ATCGCGGACGCGACCGGACGCGCGGTACTCCACGACGGTGCGATGGGCCTGCGGGTCACCGCACAGCACATCGAAGACCG
CGGCATGGCCGATCTGCACGACAGCCAGCGCATCGACGTGCTGAACCTGCGCGCCGACCTGCGCGTGAGCGCGGTGGATG
AAGTGACCGTCACCGCCGGCATGAGCAGCGGCGCACGCTCGGCCGGTTACGAGGGCACCCAGTTCGACGTCGTCGCCCCG
CGTACCGCCCGCCACGAGGACGGCGCGGTGCACCTGAAATGGCGCCGCACGCTGAGCCCCGACGACGAATGGTCGCTGTC
GTGGTACCGCAACCGCGAGCAGTCGCGCGAAGACTGGCTGCTCGATTCGCACAAGAACCTGCGCCCCGAGGTGGCCTACC
TGCGCAATCTCCCGCGGCTGGTCGTCACCGTCGACAACGACCGCGACAGCCTGCGCGACAACATCGAGTTCAGCCAGCGA
CTGCGCCCGCTGGACGACCTGCGTCTGCTGTGGGGCACCGAATGGCGCCGCGACTGGCTGCGCGCGCCGATGCTGTTCTA
CGGCGGCGACTCGCACAGCCAGCAGGAATGGCGGCTGTTCGGCAATGCCGAATGGCGGATGGCGCCACGCTGGCTGTGGA
ACATCGGCGCGATGGCCGAGCAGATCGAGGGCGACCGGCTGCGCCTCGCGCCGCGGGTGTTCCTCAACTGGCAGCCCAGC
CCGACCCAGACCTGGCGCGCCGGCTATTCGCGCGCCTGGCGCCAGCCGACGCTGTTCGAGCGCTCGGCGGACATCCGCGT
GGTGCATCCGCAGCTCGGGCTGATCATGCTCGACCACCTGCCCAATCCGGACATCCGGCCGCAGCGCATCGACGCGTGGG
AGGTCGGTTTCCTCGGCCAGCTGCCGCAACAGGGCAGTTTCGACCTGCGCCTGTTCCACGAGCGCATCGAGGACTTCATC
GTGCGGCGCGCGGTCGACCCCGCCGAACTGCCGGACAACGACATCCAGCGCGCGGCCGGCGCCACGCGCTGGGTGAACAG
CGGTGACGGCGTACGCCTGGTGGGCCTGGAATACCAGCTGCGCACGCGCCCCTGGTCCGGCGGCCAGCTCGTGCTCAGCC
ACTCACTGATCCGCGCCCATAGCGACGACGACGCGGTGCGCCGCAGCGTGGCCCCCTACACCGCCAGCCTCACCTGGCTG
CAGCGCTACGGCCCGTGGCAATCCACGCTGAGCCTGCTGCGCATGGGCGCAAGCGACTCCGGCAGCGGCTACGTGCCGGG
CTACCGCTACAAGGTGCCGGCCTATACCACGCTGGACTGGAGCATCGCGCGCACGCTGCAGGTGGGCCCCAACCCGGTGG
AGCTGCGGCTCACCGGCATCAACCTGCTCGGCAAGCACCAGGAACTGGTGCTGCGCCCGCTGCAGTCCATGCCCGGCTAC
GGCGACGACCGCCCGGCCAACGAACTCGATCGCCAGCTCCATCTGTCGGTCCGCGTCGGATTCTGA

Upstream 100 bases:

>100_bases
ACCAACATCATGAGAACCCGCGGCCAGGATGTATCGTCGAACCTGTGACACACGCGTCCTGCCGGTCGTTCTCGCCTGCC
TCGCCCTCGGCGGGGGTGCC

Downstream 100 bases:

>100_bases
ACGCCGCCGCGGTGTTGATTTTGCAGCGCCCGCCCCGATCTATGCCGGGCTTGCGTCCGGGAACGCACGGCCCGGCCGCG
GCGTCCACCCACGCATCCCG

Product: putative TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 660

Protein sequence:

>661_residues
MSAHAEEGYFETLPVVLSVSRLPQAMEDTPGAVTVIDSELIAATGYRDLARLFRLVPGMQVGQERANHHWVTYHGLGSDY
PNQMQVLVDGRSVYSPYFFGGADWGSLPIALEDIDRIEVVRGSDSAAYGSNAFLGVVNILTRHTGAETGNSVSLRGGTNG
IADATGRAVLHDGAMGLRVTAQHIEDRGMADLHDSQRIDVLNLRADLRVSAVDEVTVTAGMSSGARSAGYEGTQFDVVAP
RTARHEDGAVHLKWRRTLSPDDEWSLSWYRNREQSREDWLLDSHKNLRPEVAYLRNLPRLVVTVDNDRDSLRDNIEFSQR
LRPLDDLRLLWGTEWRRDWLRAPMLFYGGDSHSQQEWRLFGNAEWRMAPRWLWNIGAMAEQIEGDRLRLAPRVFLNWQPS
PTQTWRAGYSRAWRQPTLFERSADIRVVHPQLGLIMLDHLPNPDIRPQRIDAWEVGFLGQLPQQGSFDLRLFHERIEDFI
VRRAVDPAELPDNDIQRAAGATRWVNSGDGVRLVGLEYQLRTRPWSGGQLVLSHSLIRAHSDDDAVRRSVAPYTASLTWL
QRYGPWQSTLSLLRMGASDSGSGYVPGYRYKVPAYTTLDWSIARTLQVGPNPVELRLTGINLLGKHQELVLRPLQSMPGY
GDDRPANELDRQLHLSVRVGF

Sequences:

>Translated_661_residues
MSAHAEEGYFETLPVVLSVSRLPQAMEDTPGAVTVIDSELIAATGYRDLARLFRLVPGMQVGQERANHHWVTYHGLGSDY
PNQMQVLVDGRSVYSPYFFGGADWGSLPIALEDIDRIEVVRGSDSAAYGSNAFLGVVNILTRHTGAETGNSVSLRGGTNG
IADATGRAVLHDGAMGLRVTAQHIEDRGMADLHDSQRIDVLNLRADLRVSAVDEVTVTAGMSSGARSAGYEGTQFDVVAP
RTARHEDGAVHLKWRRTLSPDDEWSLSWYRNREQSREDWLLDSHKNLRPEVAYLRNLPRLVVTVDNDRDSLRDNIEFSQR
LRPLDDLRLLWGTEWRRDWLRAPMLFYGGDSHSQQEWRLFGNAEWRMAPRWLWNIGAMAEQIEGDRLRLAPRVFLNWQPS
PTQTWRAGYSRAWRQPTLFERSADIRVVHPQLGLIMLDHLPNPDIRPQRIDAWEVGFLGQLPQQGSFDLRLFHERIEDFI
VRRAVDPAELPDNDIQRAAGATRWVNSGDGVRLVGLEYQLRTRPWSGGQLVLSHSLIRAHSDDDAVRRSVAPYTASLTWL
QRYGPWQSTLSLLRMGASDSGSGYVPGYRYKVPAYTTLDWSIARTLQVGPNPVELRLTGINLLGKHQELVLRPLQSMPGY
GDDRPANELDRQLHLSVRVGF
>Mature_660_residues
SAHAEEGYFETLPVVLSVSRLPQAMEDTPGAVTVIDSELIAATGYRDLARLFRLVPGMQVGQERANHHWVTYHGLGSDYP
NQMQVLVDGRSVYSPYFFGGADWGSLPIALEDIDRIEVVRGSDSAAYGSNAFLGVVNILTRHTGAETGNSVSLRGGTNGI
ADATGRAVLHDGAMGLRVTAQHIEDRGMADLHDSQRIDVLNLRADLRVSAVDEVTVTAGMSSGARSAGYEGTQFDVVAPR
TARHEDGAVHLKWRRTLSPDDEWSLSWYRNREQSREDWLLDSHKNLRPEVAYLRNLPRLVVTVDNDRDSLRDNIEFSQRL
RPLDDLRLLWGTEWRRDWLRAPMLFYGGDSHSQQEWRLFGNAEWRMAPRWLWNIGAMAEQIEGDRLRLAPRVFLNWQPSP
TQTWRAGYSRAWRQPTLFERSADIRVVHPQLGLIMLDHLPNPDIRPQRIDAWEVGFLGQLPQQGSFDLRLFHERIEDFIV
RRAVDPAELPDNDIQRAAGATRWVNSGDGVRLVGLEYQLRTRPWSGGQLVLSHSLIRAHSDDDAVRRSVAPYTASLTWLQ
RYGPWQSTLSLLRMGASDSGSGYVPGYRYKVPAYTTLDWSIARTLQVGPNPVELRLTGINLLGKHQELVLRPLQSMPGYG
DDRPANELDRQLHLSVRVGF

Specific function: Involved in the initial step of iron uptake by binding ferric vibriobactin, an iron chelatin siderophore that allows V.cholerae to extract iron from the environment [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=176, Percent_Identity=34.0909090909091, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 74624; Mature: 74493

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAHAEEGYFETLPVVLSVSRLPQAMEDTPGAVTVIDSELIAATGYRDLARLFRLVPGMQ
CCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCEEEEECCHHHHHCCHHHHHHHHHHCCCCH
VGQERANHHWVTYHGLGSDYPNQMQVLVDGRSVYSPYFFGGADWGSLPIALEDIDRIEVV
HHHHHCCCCEEEEECCCCCCCCCEEEEECCCHHCCCEEECCCCCCCCCEEECCCCEEEEE
RGSDSAAYGSNAFLGVVNILTRHTGAETGNSVSLRGGTNGIADATGRAVLHDGAMGLRVT
ECCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCEEEECCCCCEEEE
AQHIEDRGMADLHDSQRIDVLNLRADLRVSAVDEVTVTAGMSSGARSAGYEGTQFDVVAP
HHHHCCCCCCCCCCCCCEEEEEECCCCEEEEECEEEEEECCCCCCCCCCCCCCEEEEECC
RTARHEDGAVHLKWRRTLSPDDEWSLSWYRNREQSREDWLLDSHKNLRPEVAYLRNLPRL
CCCCCCCCEEEEEEECCCCCCCCCCHHHHHCCCCCHHHHECCCCCCCCHHHHHHHCCCEE
VVTVDNDRDSLRDNIEFSQRLRPLDDLRLLWGTEWRRDWLRAPMLFYGGDSHSQQEWRLF
EEEECCCHHHHHHCCCHHHHCCCHHHHHHHHCCHHHHHHHCCCEEEECCCCCCCCCEEEE
GNAEWRMAPRWLWNIGAMAEQIEGDRLRLAPRVFLNWQPSPTQTWRAGYSRAWRQPTLFE
CCCCEEECHHHHHHHHHHHHHCCCCEEEECCEEEEECCCCCCHHHHHHHHHHCCCCCCEE
RSADIRVVHPQLGLIMLDHLPNPDIRPQRIDAWEVGFLGQLPQQGSFDLRLFHERIEDFI
CCCCEEEECCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHH
VRRAVDPAELPDNDIQRAAGATRWVNSGDGVRLVGLEYQLRTRPWSGGQLVLSHSLIRAH
HHHCCCCCCCCCHHHHHHCCCCEEECCCCCEEEEEEEEEEECCCCCCCEEEEEEHHHHCC
SDDDAVRRSVAPYTASLTWLQRYGPWQSTLSLLRMGASDSGSGYVPGYRYKVPAYTTLDW
CCCHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCEEEEECC
SIARTLQVGPNPVELRLTGINLLGKHQELVLRPLQSMPGYGDDRPANELDRQLHLSVRVG
EEEEEEECCCCCEEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHCCEEEEEEEEC
F
C
>Mature Secondary Structure 
SAHAEEGYFETLPVVLSVSRLPQAMEDTPGAVTVIDSELIAATGYRDLARLFRLVPGMQ
CCCCCCCCHHHHHHHHHHHHCCHHHHCCCCEEEEECCHHHHHCCHHHHHHHHHHCCCCH
VGQERANHHWVTYHGLGSDYPNQMQVLVDGRSVYSPYFFGGADWGSLPIALEDIDRIEVV
HHHHHCCCCEEEEECCCCCCCCCEEEEECCCHHCCCEEECCCCCCCCCEEECCCCEEEEE
RGSDSAAYGSNAFLGVVNILTRHTGAETGNSVSLRGGTNGIADATGRAVLHDGAMGLRVT
ECCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCEEEECCCCCEEEE
AQHIEDRGMADLHDSQRIDVLNLRADLRVSAVDEVTVTAGMSSGARSAGYEGTQFDVVAP
HHHHCCCCCCCCCCCCCEEEEEECCCCEEEEECEEEEEECCCCCCCCCCCCCCEEEEECC
RTARHEDGAVHLKWRRTLSPDDEWSLSWYRNREQSREDWLLDSHKNLRPEVAYLRNLPRL
CCCCCCCCEEEEEEECCCCCCCCCCHHHHHCCCCCHHHHECCCCCCCCHHHHHHHCCCEE
VVTVDNDRDSLRDNIEFSQRLRPLDDLRLLWGTEWRRDWLRAPMLFYGGDSHSQQEWRLF
EEEECCCHHHHHHCCCHHHHCCCHHHHHHHHCCHHHHHHHCCCEEEECCCCCCCCCEEEE
GNAEWRMAPRWLWNIGAMAEQIEGDRLRLAPRVFLNWQPSPTQTWRAGYSRAWRQPTLFE
CCCCEEECHHHHHHHHHHHHHCCCCEEEECCEEEEECCCCCCHHHHHHHHHHCCCCCCEE
RSADIRVVHPQLGLIMLDHLPNPDIRPQRIDAWEVGFLGQLPQQGSFDLRLFHERIEDFI
CCCCEEEECCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHH
VRRAVDPAELPDNDIQRAAGATRWVNSGDGVRLVGLEYQLRTRPWSGGQLVLSHSLIRAH
HHHCCCCCCCCCHHHHHHCCCCEEECCCCCEEEEEEEEEEECCCCCCCEEEEEEHHHHCC
SDDDAVRRSVAPYTASLTWLQRYGPWQSTLSLLRMGASDSGSGYVPGYRYKVPAYTTLDW
CCCHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCEEEEECC
SIARTLQVGPNPVELRLTGINLLGKHQELVLRPLQSMPGYGDDRPANELDRQLHLSVRVG
EEEEEEECCCCCEEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHCCEEEEEEEEC
F
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1406279; 2174861 [H]