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The map label for this gene is atoS [H]

Identifier: 119896364

GI number: 119896364

Start: 82158

End: 84344

Strand: Direct

Name: atoS [H]

Synonym: azo0072

Alternate gene names: 119896364

Gene position: 82158-84344 (Clockwise)

Preceding gene: 119896363

Following gene: 119896365

Centisome position: 1.88

GC content: 71.06

Gene sequence:

>2187_bases
ATGGCTGAGCGCGCCTTGCGCCGCTGGCGCAAACGCTGGCCGGTGCCGCGCTCGGTGCGGGCGCGGCTGCTGCTGCTGGT
GCTCGCGCCGCTGCTGATCGGCGTGCCGGTGCTGCTCGGCATCGTCTGGGTGTGGGGCACGCACGGCTACGACCGCCTGC
TGGTGAACAAGGTCAGCGCCGACCTGCTGACCGCGCGCCAGTATTTCGAGCGGGTGCAGCAGGGCGTGGCCGGCGACCTC
GCCGCGGTCGCCAGCTCGCACGCGCTGGCACTCGCGCTGCAGGGCCAAGGCCCGGATTCCGTCGAGGTGCTGCTCGATAC
CTCGGCCTCCCGGCTGGGGCTGGACTACCTGCTGTTCCTCGACCCGCAGGGCCGCGTCACCGTGCCCTCGGCCCCGCTGC
CCTCGGCGCTGGCCGAGCGCGGCAACTGGCCGGCGGTGCGCAGCGCGTTGCAGGGTCGCGCGGAGCACACGCTGGCGGTG
TTCCCGCCCGAACACCTCGAAGCGCTCGATCCGGCGCTGCGGGCCCATGCCACTCTCGGCCTGGTGCCTACCCAGCGCGC
CGCGCCGGATCCGCGCCCGCGCGAGGAACGCGGGCTGATGGTGCAGGTGGCGGTGCCGGTGACCGACCTCGGCGGCCGGC
TGCTCGGCGTGCTCGAAGGCGGCGTGATGCTCAACCGCAACCTCGGCATCGTCGACCGCATCAACGCTGCGGTGTACCAG
GACAGCTCGCTGCCGCTCGACAGCCAGGGCACCGCGACGCTCTTCCTCGACGACATCCGCATCGCCACCAACGTGCGCCT
GTTCGAAGGGTCGCGCGCGCTCGGCACCCGGGTGTCGGCGGCGGTGCGGGACAAGGTGCTCGGCCGCGGCGAAACCTGGC
TCGGCTCCGCCTTCGTGGTCAACGCCGACTACATCTCCGGCTACGCCCCGCTGTTCGACGGCGACGGCAAGGCGGTCGGC
ATGCTCTACGTCGGCTTCCTGCAGGCGCCGCTGCAGCAGGCGCTCTACCTCGCGCTCGGCGGGCTGTTCCTGGTGTTCCT
GCTGCTGTCCGGGCTCGGCACGCTGGCCGCGGTGCGCTGGGCGCGCTCGATCTTCCAGCCGATCGAACGGATGGCGGCGG
TGATGGGGCGGATCGAATCCGGCGAGGAGCAGGCGCGCGTCGGCGCGGTGGTGCGCGACGACGAACTCGGCGGCCTGGCG
CGCAGCTTCGACCGCCTGCTCGACCTGCTCGCCGCCCGCCGCGCCGAGCTGCAGCGCTGGGGCCAGGAACTCGACAGCAA
GGTCGCCGCCCGCACCGCCGAGCTGGAAGCCGCCAACGCCACGCTGCGCCGCGCCCACCAGCAACTGGTAATGAACGAAA
AGCTCACCGCGATCGGCGAACTCACCGCCGGCGTCGCTCACGAGATCAACAACCCGGTGGCGGTAATCCAGGGCAACCTC
GAACTGGTGCGCGAGCTGCTGGGCGGCGACAGCGCACCGGTGGCCGACGAGCTGGCGCAGATCGACGCCCAGGTCGGCCG
CATCCACGGCATCGTGACCAAGCTGCTGCAGTTCGCCCGCCCGGGCGATTTCGCCGGCTACACCGAGCAGGTGGACGCCT
CCGGCCTGGTCGGCGACTGCCTGCTGCTGACGCGCCACAACCTCAGCCGCGGCCGCATCGAGGTGACGACCGCACTCGAC
GCCCGCGGCACGGTGGAGATCAACCGCGGCGAATTGCAGCAGGTGCTGATCAACCTGATCGTCAACGCCATGCAGGCGAT
GCCGGACGGCGGCAGGCTGCGGCTGAGCACCGCCGACATCGACGAAGGCGGGGAAGACGACGATGCCGGACACGGCGCCG
GACGCAACGGCAAGAGCGAACACCGGCACGGCTTTGCCGGCGTCTGCATCCGCGTCGAGGACACCGGCTGCGGCATCGCC
GCCGACGATCTCGACCGCATCTTCGACCCCTTCTTCACCACCAAGAAGCAGGAAGGCACCGGCCTCGGGCTGTCGATCAG
CTATGCCATCGTCACCCGCTACGGCGGCCACCTCAACGTCGACAGCCAGCCGGGGCAGGGCACCCGCTTCACCGTGTGCC
TGCGCCGCGAGGCCCGCTTCGACGGTGAACCGAGCGCCCCCGGCTTCGCCAGCCGCTTCTTCCGCAGCGCGGGCATTGAC
AACTTAAATGATGGTCATCATGATTAA

Upstream 100 bases:

>100_bases
CGGCAACAAGACGCGCGCCGCGGAACTGCTCGGCGTGTCGCGCAAGACCCTGGAACGCAAGTGCGCGGAGTGGTCGGTAT
GACCCCGGCGGCACGCCGCG

Downstream 100 bases:

>100_bases
AAGCCCTCACTCGGCGAGTCCGCGATCATGCTGCGCACCCTGAACCAACCCGGCCTGTGGCTGATCACGCTGACCGCGGC
CGGCATCCTGATGGTGACCA

Product: putative sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 728; Mature: 727

Protein sequence:

>728_residues
MAERALRRWRKRWPVPRSVRARLLLLVLAPLLIGVPVLLGIVWVWGTHGYDRLLVNKVSADLLTARQYFERVQQGVAGDL
AAVASSHALALALQGQGPDSVEVLLDTSASRLGLDYLLFLDPQGRVTVPSAPLPSALAERGNWPAVRSALQGRAEHTLAV
FPPEHLEALDPALRAHATLGLVPTQRAAPDPRPREERGLMVQVAVPVTDLGGRLLGVLEGGVMLNRNLGIVDRINAAVYQ
DSSLPLDSQGTATLFLDDIRIATNVRLFEGSRALGTRVSAAVRDKVLGRGETWLGSAFVVNADYISGYAPLFDGDGKAVG
MLYVGFLQAPLQQALYLALGGLFLVFLLLSGLGTLAAVRWARSIFQPIERMAAVMGRIESGEEQARVGAVVRDDELGGLA
RSFDRLLDLLAARRAELQRWGQELDSKVAARTAELEAANATLRRAHQQLVMNEKLTAIGELTAGVAHEINNPVAVIQGNL
ELVRELLGGDSAPVADELAQIDAQVGRIHGIVTKLLQFARPGDFAGYTEQVDASGLVGDCLLLTRHNLSRGRIEVTTALD
ARGTVEINRGELQQVLINLIVNAMQAMPDGGRLRLSTADIDEGGEDDDAGHGAGRNGKSEHRHGFAGVCIRVEDTGCGIA
ADDLDRIFDPFFTTKKQEGTGLGLSISYAIVTRYGGHLNVDSQPGQGTRFTVCLRREARFDGEPSAPGFASRFFRSAGID
NLNDGHHD

Sequences:

>Translated_728_residues
MAERALRRWRKRWPVPRSVRARLLLLVLAPLLIGVPVLLGIVWVWGTHGYDRLLVNKVSADLLTARQYFERVQQGVAGDL
AAVASSHALALALQGQGPDSVEVLLDTSASRLGLDYLLFLDPQGRVTVPSAPLPSALAERGNWPAVRSALQGRAEHTLAV
FPPEHLEALDPALRAHATLGLVPTQRAAPDPRPREERGLMVQVAVPVTDLGGRLLGVLEGGVMLNRNLGIVDRINAAVYQ
DSSLPLDSQGTATLFLDDIRIATNVRLFEGSRALGTRVSAAVRDKVLGRGETWLGSAFVVNADYISGYAPLFDGDGKAVG
MLYVGFLQAPLQQALYLALGGLFLVFLLLSGLGTLAAVRWARSIFQPIERMAAVMGRIESGEEQARVGAVVRDDELGGLA
RSFDRLLDLLAARRAELQRWGQELDSKVAARTAELEAANATLRRAHQQLVMNEKLTAIGELTAGVAHEINNPVAVIQGNL
ELVRELLGGDSAPVADELAQIDAQVGRIHGIVTKLLQFARPGDFAGYTEQVDASGLVGDCLLLTRHNLSRGRIEVTTALD
ARGTVEINRGELQQVLINLIVNAMQAMPDGGRLRLSTADIDEGGEDDDAGHGAGRNGKSEHRHGFAGVCIRVEDTGCGIA
ADDLDRIFDPFFTTKKQEGTGLGLSISYAIVTRYGGHLNVDSQPGQGTRFTVCLRREARFDGEPSAPGFASRFFRSAGID
NLNDGHHD
>Mature_727_residues
AERALRRWRKRWPVPRSVRARLLLLVLAPLLIGVPVLLGIVWVWGTHGYDRLLVNKVSADLLTARQYFERVQQGVAGDLA
AVASSHALALALQGQGPDSVEVLLDTSASRLGLDYLLFLDPQGRVTVPSAPLPSALAERGNWPAVRSALQGRAEHTLAVF
PPEHLEALDPALRAHATLGLVPTQRAAPDPRPREERGLMVQVAVPVTDLGGRLLGVLEGGVMLNRNLGIVDRINAAVYQD
SSLPLDSQGTATLFLDDIRIATNVRLFEGSRALGTRVSAAVRDKVLGRGETWLGSAFVVNADYISGYAPLFDGDGKAVGM
LYVGFLQAPLQQALYLALGGLFLVFLLLSGLGTLAAVRWARSIFQPIERMAAVMGRIESGEEQARVGAVVRDDELGGLAR
SFDRLLDLLAARRAELQRWGQELDSKVAARTAELEAANATLRRAHQQLVMNEKLTAIGELTAGVAHEINNPVAVIQGNLE
LVRELLGGDSAPVADELAQIDAQVGRIHGIVTKLLQFARPGDFAGYTEQVDASGLVGDCLLLTRHNLSRGRIEVTTALDA
RGTVEINRGELQQVLINLIVNAMQAMPDGGRLRLSTADIDEGGEDDDAGHGAGRNGKSEHRHGFAGVCIRVEDTGCGIAA
DDLDRIFDPFFTTKKQEGTGLGLSISYAIVTRYGGHLNVDSQPGQGTRFTVCLRREARFDGEPSAPGFASRFFRSAGIDN
LNDGHHD

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=264, Percent_Identity=32.9545454545455, Blast_Score=133, Evalue=5e-32,
Organism=Escherichia coli, GI1790436, Length=247, Percent_Identity=37.6518218623482, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI1789149, Length=444, Percent_Identity=22.7477477477477, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1786600, Length=265, Percent_Identity=25.6603773584906, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=27.4193548387097, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788393, Length=340, Percent_Identity=23.8235294117647, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78346; Mature: 78215

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50885 HAMP ; PS00435 PEROXIDASE_1 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERALRRWRKRWPVPRSVRARLLLLVLAPLLIGVPVLLGIVWVWGTHGYDRLLVNKVSA
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
DLLTARQYFERVQQGVAGDLAAVASSHALALALQGQGPDSVEVLLDTSASRLGLDYLLFL
HHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEEECCCCCCEEEEEECCCHHCCCEEEEEE
DPQGRVTVPSAPLPSALAERGNWPAVRSALQGRAEHTLAVFPPEHLEALDPALRAHATLG
CCCCCEECCCCCCCHHHHHCCCCHHHHHHHCCCCCCEEEECCHHHHHHHCHHHHHHHHCC
LVPTQRAAPDPRPREERGLMVQVAVPVTDLGGRLLGVLEGGVMLNRNLGIVDRINAAVYQ
CCCCCCCCCCCCCCCCCCEEEEEEECHHHHCCHHHHHHCCCEEEECCCCHHHHCCHHEEE
DSSLPLDSQGTATLFLDDIRIATNVRLFEGSRALGTRVSAAVRDKVLGRGETWLGSAFVV
CCCCCCCCCCCEEEEEECEEEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCEEEE
NADYISGYAPLFDGDGKAVGMLYVGFLQAPLQQALYLALGGLFLVFLLLSGLGTLAAVRW
ECHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARSIFQPIERMAAVMGRIESGEEQARVGAVVRDDELGGLARSFDRLLDLLAARRAELQRW
HHHHHHHHHHHHHHHHHHCCCHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
GQELDSKVAARTAELEAANATLRRAHQQLVMNEKLTAIGELTAGVAHEINNPVAVIQGNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCH
ELVRELLGGDSAPVADELAQIDAQVGRIHGIVTKLLQFARPGDFAGYTEQVDASGLVGDC
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCHHHH
LLLTRHNLSRGRIEVTTALDARGTVEINRGELQQVLINLIVNAMQAMPDGGRLRLSTADI
HHHHHCCCCCCEEEEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
DEGGEDDDAGHGAGRNGKSEHRHGFAGVCIRVEDTGCGIAADDLDRIFDPFFTTKKQEGT
CCCCCCCCCCCCCCCCCCCHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
GLGLSISYAIVTRYGGHLNVDSQPGQGTRFTVCLRREARFDGEPSAPGFASRFFRSAGID
CCCEEEEEEEEECCCCEECCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCC
NLNDGHHD
CCCCCCCC
>Mature Secondary Structure 
AERALRRWRKRWPVPRSVRARLLLLVLAPLLIGVPVLLGIVWVWGTHGYDRLLVNKVSA
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
DLLTARQYFERVQQGVAGDLAAVASSHALALALQGQGPDSVEVLLDTSASRLGLDYLLFL
HHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEEECCCCCCEEEEEECCCHHCCCEEEEEE
DPQGRVTVPSAPLPSALAERGNWPAVRSALQGRAEHTLAVFPPEHLEALDPALRAHATLG
CCCCCEECCCCCCCHHHHHCCCCHHHHHHHCCCCCCEEEECCHHHHHHHCHHHHHHHHCC
LVPTQRAAPDPRPREERGLMVQVAVPVTDLGGRLLGVLEGGVMLNRNLGIVDRINAAVYQ
CCCCCCCCCCCCCCCCCCEEEEEEECHHHHCCHHHHHHCCCEEEECCCCHHHHCCHHEEE
DSSLPLDSQGTATLFLDDIRIATNVRLFEGSRALGTRVSAAVRDKVLGRGETWLGSAFVV
CCCCCCCCCCCEEEEEECEEEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCEEEE
NADYISGYAPLFDGDGKAVGMLYVGFLQAPLQQALYLALGGLFLVFLLLSGLGTLAAVRW
ECHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARSIFQPIERMAAVMGRIESGEEQARVGAVVRDDELGGLARSFDRLLDLLAARRAELQRW
HHHHHHHHHHHHHHHHHHCCCHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
GQELDSKVAARTAELEAANATLRRAHQQLVMNEKLTAIGELTAGVAHEINNPVAVIQGNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCH
ELVRELLGGDSAPVADELAQIDAQVGRIHGIVTKLLQFARPGDFAGYTEQVDASGLVGDC
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCHHHH
LLLTRHNLSRGRIEVTTALDARGTVEINRGELQQVLINLIVNAMQAMPDGGRLRLSTADI
HHHHHCCCCCCEEEEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
DEGGEDDDAGHGAGRNGKSEHRHGFAGVCIRVEDTGCGIAADDLDRIFDPFFTTKKQEGT
CCCCCCCCCCCCCCCCCCCHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
GLGLSISYAIVTRYGGHLNVDSQPGQGTRFTVCLRREARFDGEPSAPGFASRFFRSAGID
CCCEEEEEEEEECCCCEECCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCC
NLNDGHHD
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]