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The map label for this gene is glmS [H]

Identifier: 119776771

GI number: 119776771

Start: 4287696

End: 4289525

Strand: Reverse

Name: glmS [H]

Synonym: Sama_3639

Alternate gene names: 119776771

Gene position: 4289525-4287696 (Counterclockwise)

Preceding gene: 119776772

Following gene: 119776770

Centisome position: 99.61

GC content: 57.76

Gene sequence:

>1830_bases
ATGTGTGGAATCGTTGGCGCCGTGGCGCAAAGGGACGTGGCCGAAATTTTGCTCGAGGGCCTGCGTCGTCTGGAATATCG
TGGTTATGACTCTGCCGGTATGGCGGTGATTCAGAATGCCGAAATGAACCGTACCCGTCGGGTGGGGAAAGTGCAGGAGC
TGGCCGACGCACTGGCCGAAGCTCCTCTTACCGGTGGCACAGGTATTGCCCACACCCGCTGGGCGACCCACGGTGAGCCC
AGTGAGCGTAACGCGCACCCGCACCAGTCCGAGGGTGATATCGCCGTGGTGCACAACGGCATTATCGAAAACCATGCCAA
GCTGCGTGAACGCTTAAAGGGCCTGGGGTATCAGTTCAACTCAGATACAGACACCGAAGTAATTTGCCACCTGGTACACC
ATGAGCTGAAAAGTGCTGATACCTTGCTGGCTGCCGTACAAGCCACGGTTAAGCAGCTCGAAGGCGCCTATGGCACTGTG
GTTATCGACCGCCGCGACGCCGAGCGTATGGTAGTGGCCCGCAGTGGCAGCCCGCTGGTGATAGGTTTTGGTCTGGGTGA
AAACTTTGTAGCCTCAGATCAACTGGCGCTGTTGCCTGTGACCCGTACTTTCGCCTTCCTAGAAGAAGGTGATGTGGCCG
AAGTGACTCGTCGTAACGTGCGCATCTTCGATGTGGATGGCAATGAGGTTGAGCGTGAAGCCAAAGAATCGGAAGTAACC
CACGATGCCGGCGACAAGGGCGAATACCGCCACTATATGCTCAAGGAAATCTACGAGCAGCCACGTGCCCTGGCCCGTAC
CCTGGAAGGCCGCATCGCCAACATGCAGGTGCTGGACAGCGCCTTTGGCGACAAAGCTGCCGACCTTTTGAAAGACATCA
AACACGTGCAGATCATCGCCTGTGGTACCAGCTACCACGCGGGCATGACCGCCCGCTATTGGCTGGAACAATGGGCCGGC
GTGTCCTGTAACGTGGAAATCGCGTCAGAATTCCGCTATCGCAAGTCGCACCTGTTCCCAAACAGCCTGCTGGTGACCAT
CTCCCAGTCCGGTGAGACCGCCGATACCCTGGCCGCGCTGCGTTTGGCGAAGGAAATGGGCTATCAGGCCACCCTGACCA
TCTGTAATGCGCCGGGCTCGTCGCTGGTACGCGAATCTGACATGGCCTACATGATGAAAGCCGGCGCCGAAATCGGTGTG
GCCTCCACCAAGGCCTTTACCGTGCAACTGGCAGGCCTGTTGATGTTGACCGCCGTGATTGGTCGCAACAACGGCATGTC
TGCCGAGCTGCAATCCTCCTTGACCCAAAGCCTGCAATCACTGCCGGCCAAGGTTGAGCAGGCACTGGGCCTGGACGATG
CCATTGCTTCACTGGCCGAAGATTTTGCCGACAAGCATCATGCGCTGTTCCTCGGCCGTGGCGATCAGTACCCCATCGCC
ATGGAAGGAGCACTCAAGCTCAAGGAAATCTCCTACATCCACGCCGAGGCTTATGCGTCTGGCGAGCTCAAACACGGCCC
GCTGGCGCTGATTGATGCCGATATGCCGGTGATTGTGGTCGCGCCCAACAACGAGCTGCTGGAAAAATTAAAATCCAACG
TGGAAGAGGTGCGTGCCCGTGGCGGCCTGATGTATGTGTTTGCCGACAAGGACGCCGAGTTTGCGTCGGACGACACCATG
AAGGTGATCCCCGTGCCTCACTGTGATGAGTTTATGGCACCGCTCATCTATACCATTCCGCTGCAGCTGCTGTCGTATCA
CGTGGCCCTGATTAAAGGCACTGACGTCGACCAGCCACGTAACCTGGCCAAGTCAGTTACCGTGGAGTAA

Upstream 100 bases:

>100_bases
TGCCCAAAGAGGCAGTGACCATCATAGAGGCCCATGGGGTGAAGGTGTATCTGGCGGATGTTCAGTAGTTAGTTTTTACA
GACCTTACGGAAATACAAGC

Downstream 100 bases:

>100_bases
TCACGCTATCTGTTGAGTTAAGCCTCCCCCCCGGGGAGGCTTTTTTATGACATTGATTTGTCTTTTACCAGGGGATTTAA
CTTTTACTTAACCTTTGCAC

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MCGIVGAVAQRDVAEILLEGLRRLEYRGYDSAGMAVIQNAEMNRTRRVGKVQELADALAEAPLTGGTGIAHTRWATHGEP
SERNAHPHQSEGDIAVVHNGIIENHAKLRERLKGLGYQFNSDTDTEVICHLVHHELKSADTLLAAVQATVKQLEGAYGTV
VIDRRDAERMVVARSGSPLVIGFGLGENFVASDQLALLPVTRTFAFLEEGDVAEVTRRNVRIFDVDGNEVEREAKESEVT
HDAGDKGEYRHYMLKEIYEQPRALARTLEGRIANMQVLDSAFGDKAADLLKDIKHVQIIACGTSYHAGMTARYWLEQWAG
VSCNVEIASEFRYRKSHLFPNSLLVTISQSGETADTLAALRLAKEMGYQATLTICNAPGSSLVRESDMAYMMKAGAEIGV
ASTKAFTVQLAGLLMLTAVIGRNNGMSAELQSSLTQSLQSLPAKVEQALGLDDAIASLAEDFADKHHALFLGRGDQYPIA
MEGALKLKEISYIHAEAYASGELKHGPLALIDADMPVIVVAPNNELLEKLKSNVEEVRARGGLMYVFADKDAEFASDDTM
KVIPVPHCDEFMAPLIYTIPLQLLSYHVALIKGTDVDQPRNLAKSVTVE

Sequences:

>Translated_609_residues
MCGIVGAVAQRDVAEILLEGLRRLEYRGYDSAGMAVIQNAEMNRTRRVGKVQELADALAEAPLTGGTGIAHTRWATHGEP
SERNAHPHQSEGDIAVVHNGIIENHAKLRERLKGLGYQFNSDTDTEVICHLVHHELKSADTLLAAVQATVKQLEGAYGTV
VIDRRDAERMVVARSGSPLVIGFGLGENFVASDQLALLPVTRTFAFLEEGDVAEVTRRNVRIFDVDGNEVEREAKESEVT
HDAGDKGEYRHYMLKEIYEQPRALARTLEGRIANMQVLDSAFGDKAADLLKDIKHVQIIACGTSYHAGMTARYWLEQWAG
VSCNVEIASEFRYRKSHLFPNSLLVTISQSGETADTLAALRLAKEMGYQATLTICNAPGSSLVRESDMAYMMKAGAEIGV
ASTKAFTVQLAGLLMLTAVIGRNNGMSAELQSSLTQSLQSLPAKVEQALGLDDAIASLAEDFADKHHALFLGRGDQYPIA
MEGALKLKEISYIHAEAYASGELKHGPLALIDADMPVIVVAPNNELLEKLKSNVEEVRARGGLMYVFADKDAEFASDDTM
KVIPVPHCDEFMAPLIYTIPLQLLSYHVALIKGTDVDQPRNLAKSVTVE
>Mature_609_residues
MCGIVGAVAQRDVAEILLEGLRRLEYRGYDSAGMAVIQNAEMNRTRRVGKVQELADALAEAPLTGGTGIAHTRWATHGEP
SERNAHPHQSEGDIAVVHNGIIENHAKLRERLKGLGYQFNSDTDTEVICHLVHHELKSADTLLAAVQATVKQLEGAYGTV
VIDRRDAERMVVARSGSPLVIGFGLGENFVASDQLALLPVTRTFAFLEEGDVAEVTRRNVRIFDVDGNEVEREAKESEVT
HDAGDKGEYRHYMLKEIYEQPRALARTLEGRIANMQVLDSAFGDKAADLLKDIKHVQIIACGTSYHAGMTARYWLEQWAG
VSCNVEIASEFRYRKSHLFPNSLLVTISQSGETADTLAALRLAKEMGYQATLTICNAPGSSLVRESDMAYMMKAGAEIGV
ASTKAFTVQLAGLLMLTAVIGRNNGMSAELQSSLTQSLQSLPAKVEQALGLDDAIASLAEDFADKHHALFLGRGDQYPIA
MEGALKLKEISYIHAEAYASGELKHGPLALIDADMPVIVVAPNNELLEKLKSNVEEVRARGGLMYVFADKDAEFASDDTM
KVIPVPHCDEFMAPLIYTIPLQLLSYHVALIKGTDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=685, Percent_Identity=36.2043795620438, Blast_Score=398, Evalue=1e-111,
Organism=Homo sapiens, GI205277386, Length=690, Percent_Identity=37.2463768115942, Blast_Score=398, Evalue=1e-110,
Organism=Homo sapiens, GI29570798, Length=267, Percent_Identity=26.9662921348315, Blast_Score=76, Evalue=9e-14,
Organism=Escherichia coli, GI1790167, Length=610, Percent_Identity=70.1639344262295, Blast_Score=878, Evalue=0.0,
Organism=Escherichia coli, GI1788651, Length=228, Percent_Identity=32.0175438596491, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87082251, Length=315, Percent_Identity=20.6349206349206, Blast_Score=63, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17539970, Length=429, Percent_Identity=38.9277389277389, Blast_Score=285, Evalue=7e-77,
Organism=Caenorhabditis elegans, GI17532899, Length=429, Percent_Identity=38.9277389277389, Blast_Score=283, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI17532897, Length=429, Percent_Identity=38.9277389277389, Blast_Score=282, Evalue=4e-76,
Organism=Saccharomyces cerevisiae, GI6322745, Length=721, Percent_Identity=35.506241331484, Blast_Score=365, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6323731, Length=432, Percent_Identity=30.5555555555556, Blast_Score=188, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6323730, Length=205, Percent_Identity=38.5365853658537, Blast_Score=127, Evalue=5e-30,
Organism=Drosophila melanogaster, GI21357745, Length=686, Percent_Identity=36.0058309037901, Blast_Score=390, Evalue=1e-108,
Organism=Drosophila melanogaster, GI28573187, Length=267, Percent_Identity=25.8426966292135, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 66449; Mature: 66449

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAVAQRDVAEILLEGLRRLEYRGYDSAGMAVIQNAEMNRTRRVGKVQELADALAE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCHHHHHHHHHHHHHHHHHHHH
APLTGGTGIAHTRWATHGEPSERNAHPHQSEGDIAVVHNGIIENHAKLRERLKGLGYQFN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCEECC
SDTDTEVICHLVHHELKSADTLLAAVQATVKQLEGAYGTVVIDRRDAERMVVARSGSPLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCEE
IGFGLGENFVASDQLALLPVTRTFAFLEEGDVAEVTRRNVRIFDVDGNEVEREAKESEVT
EEECCCCCCCCCCCEEEEEHHHHHHHHCCCCHHHHHHCCEEEEECCCCHHHHHHHHHHCC
HDAGDKGEYRHYMLKEIYEQPRALARTLEGRIANMQVLDSAFGDKAADLLKDIKHVQIIA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCEEEEEE
CGTSYHAGMTARYWLEQWAGVSCNVEIASEFRYRKSHLFPNSLLVTISQSGETADTLAAL
ECCCCCCCCHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
RLAKEMGYQATLTICNAPGSSLVRESDMAYMMKAGAEIGVASTKAFTVQLAGLLMLTAVI
HHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
GRNNGMSAELQSSLTQSLQSLPAKVEQALGLDDAIASLAEDFADKHHALFLGRGDQYPIA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCEE
MEGALKLKEISYIHAEAYASGELKHGPLALIDADMPVIVVAPNNELLEKLKSNVEEVRAR
ECCCEEHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHC
GGLMYVFADKDAEFASDDTMKVIPVPHCDEFMAPLIYTIPLQLLSYHVALIKGTDVDQPR
CCEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHH
NLAKSVTVE
HHHHHCCCC
>Mature Secondary Structure
MCGIVGAVAQRDVAEILLEGLRRLEYRGYDSAGMAVIQNAEMNRTRRVGKVQELADALAE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCHHHHHHHHHHHHHHHHHHHH
APLTGGTGIAHTRWATHGEPSERNAHPHQSEGDIAVVHNGIIENHAKLRERLKGLGYQFN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCEECC
SDTDTEVICHLVHHELKSADTLLAAVQATVKQLEGAYGTVVIDRRDAERMVVARSGSPLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCEE
IGFGLGENFVASDQLALLPVTRTFAFLEEGDVAEVTRRNVRIFDVDGNEVEREAKESEVT
EEECCCCCCCCCCCEEEEEHHHHHHHHCCCCHHHHHHCCEEEEECCCCHHHHHHHHHHCC
HDAGDKGEYRHYMLKEIYEQPRALARTLEGRIANMQVLDSAFGDKAADLLKDIKHVQIIA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCEEEEEE
CGTSYHAGMTARYWLEQWAGVSCNVEIASEFRYRKSHLFPNSLLVTISQSGETADTLAAL
ECCCCCCCCHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
RLAKEMGYQATLTICNAPGSSLVRESDMAYMMKAGAEIGVASTKAFTVQLAGLLMLTAVI
HHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
GRNNGMSAELQSSLTQSLQSLPAKVEQALGLDDAIASLAEDFADKHHALFLGRGDQYPIA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCEE
MEGALKLKEISYIHAEAYASGELKHGPLALIDADMPVIVVAPNNELLEKLKSNVEEVRAR
ECCCEEHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHC
GGLMYVFADKDAEFASDDTMKVIPVPHCDEFMAPLIYTIPLQLLSYHVALIKGTDVDQPR
CCEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHH
NLAKSVTVE
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]