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The map label for this gene is srlR [H]

Identifier: 119776772

GI number: 119776772

Start: 4289558

End: 4290322

Strand: Reverse

Name: srlR [H]

Synonym: Sama_3640

Alternate gene names: 119776772

Gene position: 4290322-4289558 (Counterclockwise)

Preceding gene: 119776773

Following gene: 119776771

Centisome position: 99.63

GC content: 57.12

Gene sequence:

>765_bases
ATGACCAAACGCAATACTCAGCAGCGCCGCCGCAGCATTATCGAACTTCTGAATGCTCAGGGTGAGGTGAATGTGGACCA
ATTGGCGAGCGAGTTTGCCACCTCTGAGGTGACTATTCGCAAAGACCTGGCCGAGCTTGAGAAAGCGGGACTGCTGTTTC
GCCGTTATGGTGGCGCTGTGCCCTTGCCCCAGGAGCTGAATGCCCAGGCAGTGGCCATCTCCCCGGTGAAGCTTGCCATA
GCCAAAGAGGCAGCCAAACTCATCCGCGACCATAACCGCATCATCATCGACTATGGCAGCACGACCCTGGGGCTTATCCC
CGAGCTTGCCCATCGTCGCGGCTTGGTGGTGATGACCAATTCGCTGCAGCTCGCCAATGCCATTCACGAACTGGAGCAGG
AGCCCACACTTTTGATGACCGGTGGCACCTGGGATCCGCATTCAGAGAGCTTTCAGGGGCTGGTGGCCGAGCAGGTGCTG
CGCTCTTACGATTTCGATCAACTCTTTATCGGTGCCGATGGCATAGACCTCAGCCGCGGCACCACCACCTTCAACGAACT
CGTTGGCCTGTCACGTGTGATGGCCGAAGTATCGCGGGAGGTAATTGTCATGCTGGAGTCCGACAAGATAGGCCGACGCA
TTCCCAATCTCGAGCTGCCCTGGAGTCAGGTCAGCGCAGTGGTCACAGATAACAGATTGCCCAAAGAGGCAGTGACCATC
ATAGAGGCCCATGGGGTGAAGGTGTATCTGGCGGATGTTCAGTAG

Upstream 100 bases:

>100_bases
GCTGCCTTTTGTTTTCCTGCTCTAAATTTCGCTCTTGGTTATTTTGTTTCGTTTTAATATAATCTATCTTTCGATTCGAA
AGTTAAGTTGAAAGTAACGG

Downstream 100 bases:

>100_bases
TTAGTTTTTACAGACCTTACGGAAATACAAGCATGTGTGGAATCGTTGGCGCCGTGGCGCAAAGGGACGTGGCCGAAATT
TTGCTCGAGGGCCTGCGTCG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTKRNTQQRRRSIIELLNAQGEVNVDQLASEFATSEVTIRKDLAELEKAGLLFRRYGGAVPLPQELNAQAVAISPVKLAI
AKEAAKLIRDHNRIIIDYGSTTLGLIPELAHRRGLVVMTNSLQLANAIHELEQEPTLLMTGGTWDPHSESFQGLVAEQVL
RSYDFDQLFIGADGIDLSRGTTTFNELVGLSRVMAEVSREVIVMLESDKIGRRIPNLELPWSQVSAVVTDNRLPKEAVTI
IEAHGVKVYLADVQ

Sequences:

>Translated_254_residues
MTKRNTQQRRRSIIELLNAQGEVNVDQLASEFATSEVTIRKDLAELEKAGLLFRRYGGAVPLPQELNAQAVAISPVKLAI
AKEAAKLIRDHNRIIIDYGSTTLGLIPELAHRRGLVVMTNSLQLANAIHELEQEPTLLMTGGTWDPHSESFQGLVAEQVL
RSYDFDQLFIGADGIDLSRGTTTFNELVGLSRVMAEVSREVIVMLESDKIGRRIPNLELPWSQVSAVVTDNRLPKEAVTI
IEAHGVKVYLADVQ
>Mature_253_residues
TKRNTQQRRRSIIELLNAQGEVNVDQLASEFATSEVTIRKDLAELEKAGLLFRRYGGAVPLPQELNAQAVAISPVKLAIA
KEAAKLIRDHNRIIIDYGSTTLGLIPELAHRRGLVVMTNSLQLANAIHELEQEPTLLMTGGTWDPHSESFQGLVAEQVLR
SYDFDQLFIGADGIDLSRGTTTFNELVGLSRVMAEVSREVIVMLESDKIGRRIPNLELPWSQVSAVVTDNRLPKEAVTII
EAHGVKVYLADVQ

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=40.7258064516129, Blast_Score=190, Evalue=8e-50,
Organism=Escherichia coli, GI1789519, Length=253, Percent_Identity=36.7588932806324, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI226510968, Length=236, Percent_Identity=30.9322033898305, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788069, Length=250, Percent_Identity=28, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1787540, Length=249, Percent_Identity=28.1124497991968, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789829, Length=249, Percent_Identity=27.3092369477912, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790635, Length=248, Percent_Identity=25.4032258064516, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87082344, Length=250, Percent_Identity=27.2, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28103; Mature: 27971

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRNTQQRRRSIIELLNAQGEVNVDQLASEFATSEVTIRKDLAELEKAGLLFRRYGGAV
CCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCC
PLPQELNAQAVAISPVKLAIAKEAAKLIRDHNRIIIDYGSTTLGLIPELAHRRGLVVMTN
CCCHHCCCCEEEECHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCEEEEEC
SLQLANAIHELEQEPTLLMTGGTWDPHSESFQGLVAEQVLRSYDFDQLFIGADGIDLSRG
CHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCC
TTTFNELVGLSRVMAEVSREVIVMLESDKIGRRIPNLELPWSQVSAVVTDNRLPKEAVTI
CCHHHHHHHHHHHHHHHHHHEEEEECCCCHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHE
IEAHGVKVYLADVQ
EEECCEEEEEEECC
>Mature Secondary Structure 
TKRNTQQRRRSIIELLNAQGEVNVDQLASEFATSEVTIRKDLAELEKAGLLFRRYGGAV
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCC
PLPQELNAQAVAISPVKLAIAKEAAKLIRDHNRIIIDYGSTTLGLIPELAHRRGLVVMTN
CCCHHCCCCEEEECHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCEEEEEC
SLQLANAIHELEQEPTLLMTGGTWDPHSESFQGLVAEQVLRSYDFDQLFIGADGIDLSRG
CHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCC
TTTFNELVGLSRVMAEVSREVIVMLESDKIGRRIPNLELPWSQVSAVVTDNRLPKEAVTI
CCHHHHHHHHHHHHHHHHHHEEEEECCCCHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHE
IEAHGVKVYLADVQ
EEECCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062173; 9278503; 9205837 [H]