Click here to switch to the map view.

The map label for this gene is ubiC

Identifier: 119776755

GI number: 119776755

Start: 4262595

End: 4263158

Strand: Direct

Name: ubiC

Synonym: Sama_3623

Alternate gene names: 119776755

Gene position: 4262595-4263158 (Clockwise)

Preceding gene: 119776752

Following gene: 119776760

Centisome position: 98.99

GC content: 58.33

Gene sequence:

>564_bases
ATGAGTGTGACCAGTCTCAGTTTTCCTTACGGTGAATCCATTTGTTGGTATTCGCCGGATGAGCTGGACAGGTTGCCCGA
CGGTGCCCTTGCCGATTGGCTACTTGCCAGTGGCAGCCTGACGGCCAGGTTAAGAGCCCACTGCAGCCAGTTTGAGGTCC
GGGTACTCGGTGAAGCCATGCTGCCAGGCCTGCCCGGCGAACCCCAATTACCCCATACCTGGGTGCGGGAAGTCTTGCTT
ATCCTCGACGGTACTCCCTGGGTGTTCGCACGCACTCTGGTGCCAGAAGCCCTGCTGACCCGCTGCGGAGATGAATTAAC
CGCACTGGGAGACAGACCCCTTGGCGAACTCCTCTTTTCCAGCAACCTCTTCACACCGGGCCGAATCGAAATCGCTGGCT
TTCATTCCTGCGGCACCCTGGCTCGCCTCGCCGAGAGCCTGGGACAAAATGTCCATGGTCGCCTTTGGGGCCGTCGTCGC
TACTTCGAGCGGGAGGGGGACGAGCTGATTGTCAGCGAAATATTTCTCCCTGCTGCCATGGATTATATCCTCGGACCTCA
ATAA

Upstream 100 bases:

>100_bases
ACTCCTTATGGACGAATAAGCCTCAGGTCAGCAACTATCGACCGCCACATCAACATGATAGACTTGGCCCGTTGTAATTT
TCTATTGTAGCGAGCAACCC

Downstream 100 bases:

>100_bases
AAAACGCCCCAAACGGGGCGTTTTTTACATCAGGCTTGTCTGCGTCTTGCCATACCGGCAAGCACCAGCGCCAGGGTGGC
CAACCATCCCAGGCTGCCAC

Product: putative chorismate--pyruvate lyase

Products: NA

Alternate protein names: CL; CPL

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSVTSLSFPYGESICWYSPDELDRLPDGALADWLLASGSLTARLRAHCSQFEVRVLGEAMLPGLPGEPQLPHTWVREVLL
ILDGTPWVFARTLVPEALLTRCGDELTALGDRPLGELLFSSNLFTPGRIEIAGFHSCGTLARLAESLGQNVHGRLWGRRR
YFEREGDELIVSEIFLPAAMDYILGPQ

Sequences:

>Translated_187_residues
MSVTSLSFPYGESICWYSPDELDRLPDGALADWLLASGSLTARLRAHCSQFEVRVLGEAMLPGLPGEPQLPHTWVREVLL
ILDGTPWVFARTLVPEALLTRCGDELTALGDRPLGELLFSSNLFTPGRIEIAGFHSCGTLARLAESLGQNVHGRLWGRRR
YFEREGDELIVSEIFLPAAMDYILGPQ
>Mature_186_residues
SVTSLSFPYGESICWYSPDELDRLPDGALADWLLASGSLTARLRAHCSQFEVRVLGEAMLPGLPGEPQLPHTWVREVLLI
LDGTPWVFARTLVPEALLTRCGDELTALGDRPLGELLFSSNLFTPGRIEIAGFHSCGTLARLAESLGQNVHGRLWGRRRY
FEREGDELIVSEIFLPAAMDYILGPQ

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family

Homologues:

Organism=Escherichia coli, GI87082361, Length=162, Percent_Identity=33.9506172839506, Blast_Score=77, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIC_SHEAM (A1SBR9)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_929495.1
- ProteinModelPortal:   A1SBR9
- SMR:   A1SBR9
- STRING:   A1SBR9
- GeneID:   4605870
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_3623
- eggNOG:   COG3161
- HOGENOM:   HBG644467
- OMA:   PLGELLY
- ProtClustDB:   CLSK905613
- GO:   GO:0005737
- HAMAP:   MF_01632
- InterPro:   IPR007440

Pfam domain/function: PF04345 Chor_lyase

EC number: =4.1.3.40

Molecular weight: Translated: 20709; Mature: 20578

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: BINDING 76-76 BINDING 114-114

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTSLSFPYGESICWYSPDELDRLPDGALADWLLASGSLTARLRAHCSQFEVRVLGEAM
CCCCCCCCCCCCEEEEECCHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LPGLPGEPQLPHTWVREVLLILDGTPWVFARTLVPEALLTRCGDELTALGDRPLGELLFS
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHH
SNLFTPGRIEIAGFHSCGTLARLAESLGQNVHGRLWGRRRYFEREGDELIVSEIFLPAAM
CCCCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
DYILGPQ
HHHCCCC
>Mature Secondary Structure 
SVTSLSFPYGESICWYSPDELDRLPDGALADWLLASGSLTARLRAHCSQFEVRVLGEAM
CCCCCCCCCCCEEEEECCHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LPGLPGEPQLPHTWVREVLLILDGTPWVFARTLVPEALLTRCGDELTALGDRPLGELLFS
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHH
SNLFTPGRIEIAGFHSCGTLARLAESLGQNVHGRLWGRRRYFEREGDELIVSEIFLPAAM
CCCCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
DYILGPQ
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA