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The map label for this gene is fixC [C]

Identifier: 119776655

GI number: 119776655

Start: 4157301

End: 4158953

Strand: Reverse

Name: fixC [C]

Synonym: Sama_3523

Alternate gene names: 119776655

Gene position: 4158953-4157301 (Counterclockwise)

Preceding gene: 119776669

Following gene: 119776654

Centisome position: 96.58

GC content: 54.87

Gene sequence:

>1653_bases
ATGGAACGCGAATTCATGGAGTTCGATGTTGTTATCGTGGGTGCAGGCCCTGCCGGATTGGCGACAGCCTGCCGCTTAAT
GCAGATTAGCCGTGATGCAGAAAAGGAACTGACCGTTTGCGTGGTTGAAAAAGGTTCTGAGGTCGGCGCACATATTTTAT
CGGGCGCCGTGTTTGAGCCCAATGTGCTGGATGAGCTGTTCCCTGATTGGCGTGAAACGGGCGCTCCGCTCAATACCGCC
GTGACCCACGATGAAATCCATCTGCTCAAGTCCCCCCAGGACGGCAAACTGATGCCCAATGCCATGGTGCCCAAAACCAT
GCACAACGAAGGCAACTACATCATTAGTGTAGGCAACCTGGTGCGATGGCTCGGCGGTCGCGCCGAAGAGCTGGGTGTGG
AAATTTTCCCGGGCTTTGCCGCCAGTGAACTCCTGTTTAACGACGATGGCAGCGTTAAAGGCATCCTCATCGGTGACATG
GGCATAGGCGCTAATGGTGAGCCCAAAGACAGTTTTATGCCCGGCATGGAGCTGCACGCCAAATACACTGTGTTTGCCGA
GGGCTGTCGCGGTCATCTCGGTAAGCAGTTGATTGAAAAGTTCCACTTGGACAACGGCAAGACCCCACAGCATTACGGTC
TGGGTTTCAAAGAACTGTGGAAAGTACCCGAAGGCAAGCACACGCCGGGACTGGTGGTGCATACCGGTGGCTGGCCGTTG
ACCGAGTCCAAGTCATCCGGTGGTGGCTTCCTCTACCATATGGAAGATAACCAGGTGGTGGTTGGCCTCATTATCGACCT
GAATTACCAGAATCCGCACCTGAGCCCCTTCGATGAGTTTCAGCGTTACAAGACCCATCCGGTGATTGCCCAGTATCTGG
AAGGCGGCGAGCGCATCTCTTACGGCGCCCGTGCCATTACCAAGGGTGGCCTGAACTCTCTGCCCAAGATGAGTTTCCCC
GGTGGTTTGCTGATTGGCTGTGATGCAGGCACTCTGAACTTTGCCAAGATTAAAGGCACACATACCGCCATGAAGAGTGG
CATAGTGGCGGCTGAAACCCTGGCCGAAGCCCTGTTTGTTGGGGTCGAGGGGGGTAAGGATCTGGATTGCTTCCAGGAGC
GATTTGAGCAGAGCTGGCTTGGTGATGAACTGCACCGCTCCCGTAACTTTGGCCCGGCCATGCACAAGTTCGGTACCTTC
CTGGGCGGCGCCTTCAACTTTATCGACCAGAATATCTTCGGCGGCAAGTTACCCATTACCCTGCGTGACAACAAAGCGGA
TTACGCCCAAATGGGGCTGGCGAGTGATTACCCCAAAATCGACTATCCCAAGGCCGACGGTAAGCTGAGTTTCGACAAAC
TCTCGTCTGTCTATTTGTCCAACACCTTCCATGAGGAAGATCAGCCCTGCCATCTGCGCCTCAAGGATGCCACCATTCCG
CTGGCGGTAAACCTGCCAAGGTTTGATGAGCCGGCTCAGCGTTACTGCCCTGCCGGTGTGTATGAAGTGGTCGAAGAAGC
GGGTGAAAAGAAGTTCGTTATCAACGGCCAGAACTGCATCCACTGCAAGACCTGTGATATCAAGGACCCCAGCCAGAACA
TTACCTGGGTAACGCCAGAAGGCGCCGGTGGCCCCAACTATCCCAACATGTAA

Upstream 100 bases:

>100_bases
TCTACTGTGCCTGCGAGCGGATTTCGGGTAAGGTGGTTGAGTTACAGAATATAAAACACCCGTTTACATCGGGGGCACAA
GTACAGGAATGAGGTGAAAG

Downstream 100 bases:

>100_bases
AGTTGGTGGTAGGCAACTCATTGGCCGGAGAAGAAATTCTCCGGCTTTTTTATATCAGGCAATTGCGAATTGCCCAATCT
TTCGCCATAATTCGCCGCCT

Product: electron-transferring-flavoprotein dehydrogenase

Products: NA

Alternate protein names: ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase [H]

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MEREFMEFDVVIVGAGPAGLATACRLMQISRDAEKELTVCVVEKGSEVGAHILSGAVFEPNVLDELFPDWRETGAPLNTA
VTHDEIHLLKSPQDGKLMPNAMVPKTMHNEGNYIISVGNLVRWLGGRAEELGVEIFPGFAASELLFNDDGSVKGILIGDM
GIGANGEPKDSFMPGMELHAKYTVFAEGCRGHLGKQLIEKFHLDNGKTPQHYGLGFKELWKVPEGKHTPGLVVHTGGWPL
TESKSSGGGFLYHMEDNQVVVGLIIDLNYQNPHLSPFDEFQRYKTHPVIAQYLEGGERISYGARAITKGGLNSLPKMSFP
GGLLIGCDAGTLNFAKIKGTHTAMKSGIVAAETLAEALFVGVEGGKDLDCFQERFEQSWLGDELHRSRNFGPAMHKFGTF
LGGAFNFIDQNIFGGKLPITLRDNKADYAQMGLASDYPKIDYPKADGKLSFDKLSSVYLSNTFHEEDQPCHLRLKDATIP
LAVNLPRFDEPAQRYCPAGVYEVVEEAGEKKFVINGQNCIHCKTCDIKDPSQNITWVTPEGAGGPNYPNM

Sequences:

>Translated_550_residues
MEREFMEFDVVIVGAGPAGLATACRLMQISRDAEKELTVCVVEKGSEVGAHILSGAVFEPNVLDELFPDWRETGAPLNTA
VTHDEIHLLKSPQDGKLMPNAMVPKTMHNEGNYIISVGNLVRWLGGRAEELGVEIFPGFAASELLFNDDGSVKGILIGDM
GIGANGEPKDSFMPGMELHAKYTVFAEGCRGHLGKQLIEKFHLDNGKTPQHYGLGFKELWKVPEGKHTPGLVVHTGGWPL
TESKSSGGGFLYHMEDNQVVVGLIIDLNYQNPHLSPFDEFQRYKTHPVIAQYLEGGERISYGARAITKGGLNSLPKMSFP
GGLLIGCDAGTLNFAKIKGTHTAMKSGIVAAETLAEALFVGVEGGKDLDCFQERFEQSWLGDELHRSRNFGPAMHKFGTF
LGGAFNFIDQNIFGGKLPITLRDNKADYAQMGLASDYPKIDYPKADGKLSFDKLSSVYLSNTFHEEDQPCHLRLKDATIP
LAVNLPRFDEPAQRYCPAGVYEVVEEAGEKKFVINGQNCIHCKTCDIKDPSQNITWVTPEGAGGPNYPNM
>Mature_550_residues
MEREFMEFDVVIVGAGPAGLATACRLMQISRDAEKELTVCVVEKGSEVGAHILSGAVFEPNVLDELFPDWRETGAPLNTA
VTHDEIHLLKSPQDGKLMPNAMVPKTMHNEGNYIISVGNLVRWLGGRAEELGVEIFPGFAASELLFNDDGSVKGILIGDM
GIGANGEPKDSFMPGMELHAKYTVFAEGCRGHLGKQLIEKFHLDNGKTPQHYGLGFKELWKVPEGKHTPGLVVHTGGWPL
TESKSSGGGFLYHMEDNQVVVGLIIDLNYQNPHLSPFDEFQRYKTHPVIAQYLEGGERISYGARAITKGGLNSLPKMSFP
GGLLIGCDAGTLNFAKIKGTHTAMKSGIVAAETLAEALFVGVEGGKDLDCFQERFEQSWLGDELHRSRNFGPAMHKFGTF
LGGAFNFIDQNIFGGKLPITLRDNKADYAQMGLASDYPKIDYPKADGKLSFDKLSSVYLSNTFHEEDQPCHLRLKDATIP
LAVNLPRFDEPAQRYCPAGVYEVVEEAGEKKFVINGQNCIHCKTCDIKDPSQNITWVTPEGAGGPNYPNM

Specific function: Accepts electrons from ETF and reduces ubiquinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=560, Percent_Identity=52.5, Blast_Score=572, Evalue=1e-163,
Organism=Escherichia coli, GI1786227, Length=332, Percent_Identity=26.2048192771084, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787991, Length=397, Percent_Identity=25.9445843828715, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI87082155, Length=380, Percent_Identity=26.0526315789474, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25144720, Length=560, Percent_Identity=51.7857142857143, Blast_Score=555, Evalue=1e-158,
Organism=Saccharomyces cerevisiae, GI6324932, Length=570, Percent_Identity=44.3859649122807, Blast_Score=464, Evalue=1e-131,
Organism=Drosophila melanogaster, GI24652256, Length=557, Percent_Identity=53.1418312387792, Blast_Score=577, Evalue=1e-164,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR007859
- InterPro:   IPR003042 [H]

Pfam domain/function: PF05187 ETF_QO [H]

EC number: =1.5.5.1 [H]

Molecular weight: Translated: 60193; Mature: 60193

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEREFMEFDVVIVGAGPAGLATACRLMQISRDAEKELTVCVVEKGSEVGAHILSGAVFEP
CCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHCCCCCCC
NVLDELFPDWRETGAPLNTAVTHDEIHLLKSPQDGKLMPNAMVPKTMHNEGNYIISVGNL
HHHHHHCCCHHHHCCCCCCEEECCCEEEECCCCCCCCCCCCCCCCEECCCCCEEEEHHHH
VRWLGGRAEELGVEIFPGFAASELLFNDDGSVKGILIGDMGIGANGEPKDSFMPGMELHA
HHHHCCCHHHCCEEEECCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCHHCCCCCEEEE
KYTVFAEGCRGHLGKQLIEKFHLDNGKTPQHYGLGFKELWKVPEGKHTPGLVVHTGGWPL
EEEEEECCHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHCCCCCCCCCCEEEECCCCCC
TESKSSGGGFLYHMEDNQVVVGLIIDLNYQNPHLSPFDEFQRYKTHPVIAQYLEGGERIS
CCCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHCCCCEEE
YGARAITKGGLNSLPKMSFPGGLLIGCDAGTLNFAKIKGTHTAMKSGIVAAETLAEALFV
CCHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCHHHHHHCCCHHHHHHHHHHEE
GVEGGKDLDCFQERFEQSWLGDELHRSRNFGPAMHKFGTFLGGAFNFIDQNIFGGKLPIT
ECCCCCCHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
LRDNKADYAQMGLASDYPKIDYPKADGKLSFDKLSSVYLSNTFHEEDQPCHLRLKDATIP
EECCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCEEE
LAVNLPRFDEPAQRYCPAGVYEVVEEAGEKKFVINGQNCIHCKTCDIKDPSQNITWVTPE
EEEECCCCCCHHHHHCCCHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCCCCEEEECCC
GAGGPNYPNM
CCCCCCCCCC
>Mature Secondary Structure
MEREFMEFDVVIVGAGPAGLATACRLMQISRDAEKELTVCVVEKGSEVGAHILSGAVFEP
CCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHCCCCCCC
NVLDELFPDWRETGAPLNTAVTHDEIHLLKSPQDGKLMPNAMVPKTMHNEGNYIISVGNL
HHHHHHCCCHHHHCCCCCCEEECCCEEEECCCCCCCCCCCCCCCCEECCCCCEEEEHHHH
VRWLGGRAEELGVEIFPGFAASELLFNDDGSVKGILIGDMGIGANGEPKDSFMPGMELHA
HHHHCCCHHHCCEEEECCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCHHCCCCCEEEE
KYTVFAEGCRGHLGKQLIEKFHLDNGKTPQHYGLGFKELWKVPEGKHTPGLVVHTGGWPL
EEEEEECCHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHCCCCCCCCCCEEEECCCCCC
TESKSSGGGFLYHMEDNQVVVGLIIDLNYQNPHLSPFDEFQRYKTHPVIAQYLEGGERIS
CCCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHCCCCEEE
YGARAITKGGLNSLPKMSFPGGLLIGCDAGTLNFAKIKGTHTAMKSGIVAAETLAEALFV
CCHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCHHHHHHCCCHHHHHHHHHHEE
GVEGGKDLDCFQERFEQSWLGDELHRSRNFGPAMHKFGTFLGGAFNFIDQNIFGGKLPIT
ECCCCCCHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
LRDNKADYAQMGLASDYPKIDYPKADGKLSFDKLSSVYLSNTFHEEDQPCHLRLKDATIP
EECCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCEEE
LAVNLPRFDEPAQRYCPAGVYEVVEEAGEKKFVINGQNCIHCKTCDIKDPSQNITWVTPE
EEEECCCCCCHHHHHCCCHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCCCCEEEECCC
GAGGPNYPNM
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]