Click here to switch to the map view.

The map label for this gene is nfuA

Identifier: 119776634

GI number: 119776634

Start: 4134324

End: 4134902

Strand: Reverse

Name: nfuA

Synonym: Sama_3502

Alternate gene names: 119776634

Gene position: 4134902-4134324 (Counterclockwise)

Preceding gene: 119776636

Following gene: 119776632

Centisome position: 96.02

GC content: 53.02

Gene sequence:

>579_bases
ATGATTACCATTTCCGAAGCGGCTCAGGCCCACTTTGTGAAGTTGCTGGCCGATCAACCAGAAGGTACCAACATCCGCGT
ATTTGTGATTAGTCCTGGTACTGCCCAAGCGGAGTGTGGTGTGTCCTACTGCCCGCCAGATGCCGTGGAAGATGATGATA
TTGAACTGGAGTTCAACGGTTTCAATGCCATGGTTGATGAGAAAAGCGCTCCTTTCCTGGAAGATGCCAGCATAGATTTG
GTCACTGATCAGCTTGGCTCACAGCTCACGCTCAAGGCGCCCAATGCCAAAATGCGCAAGGTGTCGGCTGATGCGTCTCT
GGTCGAGCGTATCGAATACGTCATTCAGGCTGAAATCAACCCGCAGCTGGCGAGCCACGGCGGTAACATTCTGCTGGTGG
AAGTGACTGATGATGGTGTGGCCGTTATCCAGTTCGGTGGTGGTTGTAACGGTTGCTCCATGGTGGATGTCACTCTGAAG
GATGGTATCGAGAAACAGCTGCTGGATATGTTCCCGGGTGAGCTGACCGAAGTGCGCGATGCCACTGAGCACCAACACGG
TAGTCACTCTTACCAGTGA

Upstream 100 bases:

>100_bases
GGTGGCGTATAAGCCAGGACTACAATCTGGTTTCTATCCGGAGTATCATAGCCGGTAATTCTTAGTAATTTACTCAGGTT
TCCCTGATGGAGCGCTCTAC

Downstream 100 bases:

>100_bases
TGCCTGACAATAAAAAACGCGGCCCGATGGCCGCGTTTTTTATTGGACTAACAGATAGCTCTCGTTCAATTTAAACCATT
TTCGGCCATATTTCAGGCAA

Product: putative DNA uptake protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MITISEAAQAHFVKLLADQPEGTNIRVFVISPGTAQAECGVSYCPPDAVEDDDIELEFNGFNAMVDEKSAPFLEDASIDL
VTDQLGSQLTLKAPNAKMRKVSADASLVERIEYVIQAEINPQLASHGGNILLVEVTDDGVAVIQFGGGCNGCSMVDVTLK
DGIEKQLLDMFPGELTEVRDATEHQHGSHSYQ

Sequences:

>Translated_192_residues
MITISEAAQAHFVKLLADQPEGTNIRVFVISPGTAQAECGVSYCPPDAVEDDDIELEFNGFNAMVDEKSAPFLEDASIDL
VTDQLGSQLTLKAPNAKMRKVSADASLVERIEYVIQAEINPQLASHGGNILLVEVTDDGVAVIQFGGGCNGCSMVDVTLK
DGIEKQLLDMFPGELTEVRDATEHQHGSHSYQ
>Mature_192_residues
MITISEAAQAHFVKLLADQPEGTNIRVFVISPGTAQAECGVSYCPPDAVEDDDIELEFNGFNAMVDEKSAPFLEDASIDL
VTDQLGSQLTLKAPNAKMRKVSADASLVERIEYVIQAEINPQLASHGGNILLVEVTDDGVAVIQFGGGCNGCSMVDVTLK
DGIEKQLLDMFPGELTEVRDATEHQHGSHSYQ

Specific function: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins

COG id: COG0694

COG function: function code O; Thioredoxin-like proteins and domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nfuA family

Homologues:

Organism=Escherichia coli, GI1789819, Length=191, Percent_Identity=73.2984293193717, Blast_Score=292, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NFUA_SHEAM (A1SBE8)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_929374.1
- ProteinModelPortal:   A1SBE8
- STRING:   A1SBE8
- GeneID:   4605749
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_3502
- NMPDR:   fig|326297.7.peg.3299
- eggNOG:   COG0316
- HOGENOM:   HBG289644
- OMA:   CQGCSAV
- PhylomeDB:   A1SBE8
- ProtClustDB:   PRK11190
- HAMAP:   MF_01637
- InterPro:   IPR017726
- InterPro:   IPR000361
- InterPro:   IPR001075
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- ProDom:   PD002830
- TIGRFAMs:   TIGR03341

Pfam domain/function: PF01521 Fe-S_biosyn; PF01106 NifU; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 20650; Mature: 20650

Theoretical pI: Translated: 4.01; Mature: 4.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITISEAAQAHFVKLLADQPEGTNIRVFVISPGTAQAECGVSYCPPDAVEDDDIELEFNG
CEECCHHHHHHHHHEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECC
FNAMVDEKSAPFLEDASIDLVTDQLGSQLTLKAPNAKMRKVSADASLVERIEYVIQAEIN
CEEEECCCCCCCCCCCCEEEEECCCCCEEEEECCCCHHEEECCCHHHHHHHHHHEEECCC
PQLASHGGNILLVEVTDDGVAVIQFGGGCNGCSMVDVTLKDGIEKQLLDMFPGELTEVRD
CHHHHCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEHHHCCHHHHHHHHCCCHHHHHHH
ATEHQHGSHSYQ
HHHCCCCCCCCC
>Mature Secondary Structure
MITISEAAQAHFVKLLADQPEGTNIRVFVISPGTAQAECGVSYCPPDAVEDDDIELEFNG
CEECCHHHHHHHHHEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECC
FNAMVDEKSAPFLEDASIDLVTDQLGSQLTLKAPNAKMRKVSADASLVERIEYVIQAEIN
CEEEECCCCCCCCCCCCEEEEECCCCCEEEEECCCCHHEEECCCHHHHHHHHHHEEECCC
PQLASHGGNILLVEVTDDGVAVIQFGGGCNGCSMVDVTLKDGIEKQLLDMFPGELTEVRD
CHHHHCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEHHHCCHHHHHHHHCCCHHHHHHH
ATEHQHGSHSYQ
HHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA