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The map label for this gene is pip [H]

Identifier: 119776535

GI number: 119776535

Start: 4029278

End: 4030165

Strand: Reverse

Name: pip [H]

Synonym: Sama_3403

Alternate gene names: 119776535

Gene position: 4030165-4029278 (Counterclockwise)

Preceding gene: 119776536

Following gene: 119776534

Centisome position: 93.59

GC content: 58.0

Gene sequence:

>888_bases
TTGGCGGAGTATGGCAATCCCAATGGCGTTCCACTTTTGTATCTCCACGGAGGGCCCGGTGCCGGTTGCAGCAGTGATGA
TGCCCTGCTGTTTGATGGTCGCCACTGGCGTATCTTGCTGCTTGATCAACGCGGTGCCGGTTTATCTCGTCCCCGTGGTG
GGTTGGAGCACAATGGCCTGACACAGCTGCTGGCCGATATGGAAGTGGTGCGGGAAACTCTGGGTATCGAAAATTGGTGT
CTCGCAGGTGGCTCTTTCGGTGCCACTCTCGGACTTATCTACAGTGGGCGCCATCCCGACCGCGTTATCGCCCAGAGTTA
CTGGGGGCTGTTTATCCCTTCCAGTGAGGGGATGGCCTGGCTATACGGCCCGGCGGGAGCAGCCCGACTTTTTCCTGATG
AATACAACAGCTTCAGTGCCGGGATCCCGGTAAAGGGCTGGTTGTCATTACTGTTTGAGTATTTCAGCAAGGGGTTTGTG
CATGCCAATCAGGCCGTGTCCGAGCGTGCGTTCAGGCGCTGGCTGGATTGGGAGCTGGCACTGGCCTATCCCGGCAATCA
CTTGCTCGGTCCCATCGATTGGCGCTCCCGGGTGCTGGCACTTATCGAATTACACTATGCCAGAAGTGGCTATTTCGACG
CAGAAACCGCTTTTGTGGCGGCATTACCCGACATCCGTGCCCATACCCGCATCCTTCAGGGGGAATGTGATTGGGTGTGC
CCTGCCGAGATAGCAAGGCACTACGGGCCCCTTGAAGCACGACTGGGGCGGGACTTTGAGCTGGTTACCGTGGTCGGTGG
TTATCACTCCCTCGCCGATGGTCGCATGCACAAGGCGGTGTGCGCAGCAGCAAACTGGATGCTGTCGGTGTGGCATCAAC
ACTGCTGA

Upstream 100 bases:

>100_bases
TCCACCAAACCCAAAACCGACAATGACCCGGGTTGAACAGGCACCGCCGCCGCTCATCAGCAGCAAGTGGATTGCCGTTG
GTGATGGTCATAGTCTGCAT

Downstream 100 bases:

>100_bases
AGCCTGCGGATGGGATTCAGGTGGAGGCTATGGCACAATCGCCGGGTCTTCCATCAGGCAAGGAATAATCTGTGATTGCA
TTGATACAAAGGGTCAGCCG

Product: proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MAEYGNPNGVPLLYLHGGPGAGCSSDDALLFDGRHWRILLLDQRGAGLSRPRGGLEHNGLTQLLADMEVVRETLGIENWC
LAGGSFGATLGLIYSGRHPDRVIAQSYWGLFIPSSEGMAWLYGPAGAARLFPDEYNSFSAGIPVKGWLSLLFEYFSKGFV
HANQAVSERAFRRWLDWELALAYPGNHLLGPIDWRSRVLALIELHYARSGYFDAETAFVAALPDIRAHTRILQGECDWVC
PAEIARHYGPLEARLGRDFELVTVVGGYHSLADGRMHKAVCAAANWMLSVWHQHC

Sequences:

>Translated_295_residues
MAEYGNPNGVPLLYLHGGPGAGCSSDDALLFDGRHWRILLLDQRGAGLSRPRGGLEHNGLTQLLADMEVVRETLGIENWC
LAGGSFGATLGLIYSGRHPDRVIAQSYWGLFIPSSEGMAWLYGPAGAARLFPDEYNSFSAGIPVKGWLSLLFEYFSKGFV
HANQAVSERAFRRWLDWELALAYPGNHLLGPIDWRSRVLALIELHYARSGYFDAETAFVAALPDIRAHTRILQGECDWVC
PAEIARHYGPLEARLGRDFELVTVVGGYHSLADGRMHKAVCAAANWMLSVWHQHC
>Mature_294_residues
AEYGNPNGVPLLYLHGGPGAGCSSDDALLFDGRHWRILLLDQRGAGLSRPRGGLEHNGLTQLLADMEVVRETLGIENWCL
AGGSFGATLGLIYSGRHPDRVIAQSYWGLFIPSSEGMAWLYGPAGAARLFPDEYNSFSAGIPVKGWLSLLFEYFSKGFVH
ANQAVSERAFRRWLDWELALAYPGNHLLGPIDWRSRVLALIELHYARSGYFDAETAFVAALPDIRAHTRILQGECDWVCP
AEIARHYGPLEARLGRDFELVTVVGGYHSLADGRMHKAVCAAANWMLSVWHQHC

Specific function: Hydrolyzes peptides having the structure Pro-Y-Z to yield free proline. Also hydrolyzes the dipeptide Pro-Gly [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 32635; Mature: 32504

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEYGNPNGVPLLYLHGGPGAGCSSDDALLFDGRHWRILLLDQRGAGLSRPRGGLEHNGL
CCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCH
TQLLADMEVVRETLGIENWCLAGGSFGATLGLIYSGRHPDRVIAQSYWGLFIPSSEGMAW
HHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEEECCCCCHHHHHHHHCEEEEECCCCCEE
LYGPAGAARLFPDEYNSFSAGIPVKGWLSLLFEYFSKGFVHANQAVSERAFRRWLDWELA
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEE
LAYPGNHLLGPIDWRSRVLALIELHYARSGYFDAETAFVAALPDIRAHTRILQGECDWVC
EECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHEEEEECCCHHHHHHHHCCCCCEEC
PAEIARHYGPLEARLGRDFELVTVVGGYHSLADGRMHKAVCAAANWMLSVWHQHC
HHHHHHHCCCHHHHHCCCEEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEYGNPNGVPLLYLHGGPGAGCSSDDALLFDGRHWRILLLDQRGAGLSRPRGGLEHNGL
CCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCH
TQLLADMEVVRETLGIENWCLAGGSFGATLGLIYSGRHPDRVIAQSYWGLFIPSSEGMAW
HHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEEECCCCCHHHHHHHHCEEEEECCCCCEE
LYGPAGAARLFPDEYNSFSAGIPVKGWLSLLFEYFSKGFVHANQAVSERAFRRWLDWELA
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEE
LAYPGNHLLGPIDWRSRVLALIELHYARSGYFDAETAFVAALPDIRAHTRILQGECDWVC
EECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHEEEEECCCHHHHHHHHCCCCCEEC
PAEIARHYGPLEARLGRDFELVTVVGGYHSLADGRMHKAVCAAANWMLSVWHQHC
HHHHHHHCCCHHHHHCCCEEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934933 [H]