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The map label for this gene is dtd

Identifier: 119776534

GI number: 119776534

Start: 4028769

End: 4029206

Strand: Reverse

Name: dtd

Synonym: Sama_3402

Alternate gene names: 119776534

Gene position: 4029206-4028769 (Counterclockwise)

Preceding gene: 119776535

Following gene: 119776533

Centisome position: 93.57

GC content: 59.59

Gene sequence:

>438_bases
GTGATTGCATTGATACAAAGGGTCAGCCGTGCCAGCGTCACCGTGGACGGTGAAATCACCGGCGCCATCGATCAGGGGCT
GCTGGTGTTGCTGGGGGTTGAGCAGCATGACGACCGCACCAAGCTGGAGAAATTGGCGCACAAGGTCATGAACTATCGCG
TATTTTCCGACGAAAATGGCAAGATGAATCTCAATGTCTCCCAGGTAGGGGGCAGCTTGCTGGTGGTTTCCCAGTTCACC
CTGGCGGCCGATACGGGCCGTGGGCTGCGCCCCAGTTTCTCGGGTGCCGGCACTCCAGAGCAAGCCGAGCGTCTGTACGA
CGAGTTTGTGGCCCATTGCCGCGCGCAGGGTGTGCCCACCCAAACCGGACGTTTTGCCGCCGATATGAAGGTGGAACTGC
TGAACGACGGGCCCGTGACCTTCCATTTGCAGGTGTAG

Upstream 100 bases:

>100_bases
TGCTGTCGGTGTGGCATCAACACTGCTGAAGCCTGCGGATGGGATTCAGGTGGAGGCTATGGCACAATCGCCGGGTCTTC
CATCAGGCAAGGAATAATCT

Downstream 100 bases:

>100_bases
CATGACACCAGAACAGACCTTACTGCAGGAGCTGGCGGACACCTGGCACAGCACCATCCCCCTGAGCGCCTTTATGCAAA
TCTGTCCACGCAGATACGAT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MIALIQRVSRASVTVDGEITGAIDQGLLVLLGVEQHDDRTKLEKLAHKVMNYRVFSDENGKMNLNVSQVGGSLLVVSQFT
LAADTGRGLRPSFSGAGTPEQAERLYDEFVAHCRAQGVPTQTGRFAADMKVELLNDGPVTFHLQV

Sequences:

>Translated_145_residues
MIALIQRVSRASVTVDGEITGAIDQGLLVLLGVEQHDDRTKLEKLAHKVMNYRVFSDENGKMNLNVSQVGGSLLVVSQFT
LAADTGRGLRPSFSGAGTPEQAERLYDEFVAHCRAQGVPTQTGRFAADMKVELLNDGPVTFHLQV
>Mature_145_residues
MIALIQRVSRASVTVDGEITGAIDQGLLVLLGVEQHDDRTKLEKLAHKVMNYRVFSDENGKMNLNVSQVGGSLLVVSQFT
LAADTGRGLRPSFSGAGTPEQAERLYDEFVAHCRAQGVPTQTGRFAADMKVELLNDGPVTFHLQV

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=147, Percent_Identity=43.5374149659864, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1790320, Length=145, Percent_Identity=69.6551724137931, Blast_Score=209, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI115533292, Length=143, Percent_Identity=37.0629370629371, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6319982, Length=146, Percent_Identity=36.986301369863, Blast_Score=100, Evalue=6e-23,
Organism=Drosophila melanogaster, GI281361569, Length=146, Percent_Identity=36.986301369863, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_SHEAM (A1SB48)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_929274.1
- ProteinModelPortal:   A1SB48
- SMR:   A1SB48
- STRING:   A1SB48
- GeneID:   4605649
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_3402
- NMPDR:   fig|326297.7.peg.3204
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- PhylomeDB:   A1SB48
- ProtClustDB:   PRK05273
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 15739; Mature: 15739

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALIQRVSRASVTVDGEITGAIDQGLLVLLGVEQHDDRTKLEKLAHKVMNYRVFSDENG
CHHHHHHHHHCEEEECCEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEEECCCC
KMNLNVSQVGGSLLVVSQFTLAADTGRGLRPSFSGAGTPEQAERLYDEFVAHCRAQGVPT
EEEEEHHHCCCEEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
QTGRFAADMKVELLNDGPVTFHLQV
CCCCEEECEEEEEECCCCEEEEEEC
>Mature Secondary Structure
MIALIQRVSRASVTVDGEITGAIDQGLLVLLGVEQHDDRTKLEKLAHKVMNYRVFSDENG
CHHHHHHHHHCEEEECCEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEEECCCC
KMNLNVSQVGGSLLVVSQFTLAADTGRGLRPSFSGAGTPEQAERLYDEFVAHCRAQGVPT
EEEEEHHHCCCEEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
QTGRFAADMKVELLNDGPVTFHLQV
CCCCEEECEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA