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The map label for this gene is hss [H]

Identifier: 119776469

GI number: 119776469

Start: 3965553

End: 3966968

Strand: Reverse

Name: hss [H]

Synonym: Sama_3337

Alternate gene names: 119776469

Gene position: 3966968-3965553 (Counterclockwise)

Preceding gene: 119776470

Following gene: 119776464

Centisome position: 92.12

GC content: 58.26

Gene sequence:

>1416_bases
ATGACTGAGCCAATCAAGTACGTCAAAGCCCCGGGCCGCATCCTGATAGTCGGCTTTGGCAGCATAGGTCAGGGACTGCT
GCCGCTTATCCTGCGCCACATCGATATCACACCCCAAAAAATCTGCATCATTACCGCCGACGACAGAGGCCGCGAAGAGG
CCGGGAAACTGGGTATTCGTTTTATCGAGATGCCCCTGACCCGCAAGAATTACCAGAGTGAACTCACACCGCTGGTGGGC
AAGGATGACTTTTTGGTGAATCTGTCGGTGGACGTGTCCTCCATCGCCCTGGTTGAGTTTTGTCAGGCCCGTGGCGCCCG
TTATCTGGATACCTGTATCGAGCCCTGGGCGGGCGGTTACACCGACCCCAGCAAGTCTTTTGCCGCCCGCTCCAACTATG
CCCTGCGTGAGCGGGTGCTGGCGCTGAAAGACAAATACCGCGGCGGCCCCACTGCCGTGGTGGCTCAGGGGGCCAATCCG
GGCATGGTGTCCCATCTGGTGAAACAGGCGCTGATGAACCTGCAGCAGGATATTCTCGGTACCCAGAGTGAACCCAAAAG
CCGCGAGGAGTGGGCCAAACTCGCCCACGACCTCAACATCGAGGTCATTCACATCGCTGAGCGCGACACCCAGGTGGCCA
ATCAGGCCAAGGCCATGGATGAGTTTGTGAATACCTGGTCCTGCGATGGCTTTGTCAGCGAAGGCGCTCAGCCAGCCGAA
CTGGGTTGGGGTACCCACGAGAAACACTTCCCCCGTGATGCTGGTCGCCACGAGGAAGGCTGCGGCGCGGCCATTTACTT
AAAATGCCCCGGCGCCACGGTCAAGGTGCGCACCTGGACCCCTAACTACGGTCATTTTCACGGCTTTTTGATCACCCATA
ACGAAGCCATCTCCATCGCCGATTTCTTTACCCTCAAGCAAGAGGGCAAGTTGGTGTATCGGCCCACCTGCCATTATGCC
TACCACCCCTGCGACGATGCAGTGATGTCGCTGCATGAGTTCAACGGCAAAAACTTCCAGATGCAGTCGCGCCAGCGGCT
GATGCGGGACGAGATTGTCAGCGGCATCGACGAGCTGGGGGTGCTGCTGGCAGGTCATAAGAAGAATGCCTACTGGTATG
GCTCGCAGCTGTCTATTGATGAGGCGAGGGCCCTGGTTCCCTTTAATGGTGCCACCAGTCTGCAGGTCACCTCGGCGGCG
CTGGCGGGCATTGTCTGGGCGCTGGAAAACCCCAATGCCGGGGTGGTGGAGTCGGACGAGATGGATTATCGCCGCAATCT
TGAGATCATGGCGCCTTATCTTGGTCCTGTGGTGGGGGAGTACACCGACTGGACACCGCTCTATCAGCGTGGCGAACTGT
TTCCGGAAGATGTGGATGACGACTACGCCTGGCAATTCAAAAACGTGCGGGTGTAG

Upstream 100 bases:

>100_bases
CAGGTTGAATGTCTGGCAGGCGGAATTTGCGTTCATCCGCCGATGAATATTCCATGGCCTCGGATATACAGGCATTGCTG
GAAGGAGGTTTCTCACCAAC

Downstream 100 bases:

>100_bases
CGCCTAAAAAACAAAAAGCACCACGGGAAATCCCCGTGGCGAGAGGATATGACCAAACCGCAGCGCCGGTGGAAGTGGAG
GTCGGCGCTGATACCCGGGG

Product: homospermidine synthase

Products: NA

Alternate protein names: HSS [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MTEPIKYVKAPGRILIVGFGSIGQGLLPLILRHIDITPQKICIITADDRGREEAGKLGIRFIEMPLTRKNYQSELTPLVG
KDDFLVNLSVDVSSIALVEFCQARGARYLDTCIEPWAGGYTDPSKSFAARSNYALRERVLALKDKYRGGPTAVVAQGANP
GMVSHLVKQALMNLQQDILGTQSEPKSREEWAKLAHDLNIEVIHIAERDTQVANQAKAMDEFVNTWSCDGFVSEGAQPAE
LGWGTHEKHFPRDAGRHEEGCGAAIYLKCPGATVKVRTWTPNYGHFHGFLITHNEAISIADFFTLKQEGKLVYRPTCHYA
YHPCDDAVMSLHEFNGKNFQMQSRQRLMRDEIVSGIDELGVLLAGHKKNAYWYGSQLSIDEARALVPFNGATSLQVTSAA
LAGIVWALENPNAGVVESDEMDYRRNLEIMAPYLGPVVGEYTDWTPLYQRGELFPEDVDDDYAWQFKNVRV

Sequences:

>Translated_471_residues
MTEPIKYVKAPGRILIVGFGSIGQGLLPLILRHIDITPQKICIITADDRGREEAGKLGIRFIEMPLTRKNYQSELTPLVG
KDDFLVNLSVDVSSIALVEFCQARGARYLDTCIEPWAGGYTDPSKSFAARSNYALRERVLALKDKYRGGPTAVVAQGANP
GMVSHLVKQALMNLQQDILGTQSEPKSREEWAKLAHDLNIEVIHIAERDTQVANQAKAMDEFVNTWSCDGFVSEGAQPAE
LGWGTHEKHFPRDAGRHEEGCGAAIYLKCPGATVKVRTWTPNYGHFHGFLITHNEAISIADFFTLKQEGKLVYRPTCHYA
YHPCDDAVMSLHEFNGKNFQMQSRQRLMRDEIVSGIDELGVLLAGHKKNAYWYGSQLSIDEARALVPFNGATSLQVTSAA
LAGIVWALENPNAGVVESDEMDYRRNLEIMAPYLGPVVGEYTDWTPLYQRGELFPEDVDDDYAWQFKNVRV
>Mature_470_residues
TEPIKYVKAPGRILIVGFGSIGQGLLPLILRHIDITPQKICIITADDRGREEAGKLGIRFIEMPLTRKNYQSELTPLVGK
DDFLVNLSVDVSSIALVEFCQARGARYLDTCIEPWAGGYTDPSKSFAARSNYALRERVLALKDKYRGGPTAVVAQGANPG
MVSHLVKQALMNLQQDILGTQSEPKSREEWAKLAHDLNIEVIHIAERDTQVANQAKAMDEFVNTWSCDGFVSEGAQPAEL
GWGTHEKHFPRDAGRHEEGCGAAIYLKCPGATVKVRTWTPNYGHFHGFLITHNEAISIADFFTLKQEGKLVYRPTCHYAY
HPCDDAVMSLHEFNGKNFQMQSRQRLMRDEIVSGIDELGVLLAGHKKNAYWYGSQLSIDEARALVPFNGATSLQVTSAAL
AGIVWALENPNAGVVESDEMDYRRNLEIMAPYLGPVVGEYTDWTPLYQRGELFPEDVDDDYAWQFKNVRV

Specific function: Involved in the NAD(+)-dependent synthesis of the polyamine homospermidine from putrescine [H]

COG id: COG5310

COG function: function code Q; Homospermidine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023181
- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: =2.5.1.44 [H]

Molecular weight: Translated: 52564; Mature: 52433

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPIKYVKAPGRILIVGFGSIGQGLLPLILRHIDITPQKICIITADDRGREEAGKLGIR
CCCCCHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCCEE
FIEMPLTRKNYQSELTPLVGKDDFLVNLSVDVSSIALVEFCQARGARYLDTCIEPWAGGY
EEECCCCCCCHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
TDPSKSFAARSNYALRERVLALKDKYRGGPTAVVAQGANPGMVSHLVKQALMNLQQDILG
CCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHC
TQSEPKSREEWAKLAHDLNIEVIHIAERDTQVANQAKAMDEFVNTWSCDGFVSEGAQPAE
CCCCCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHH
LGWGTHEKHFPRDAGRHEEGCGAAIYLKCPGATVKVRTWTPNYGHFHGFLITHNEAISIA
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCEEEEEEECCCEEEHH
DFFTLKQEGKLVYRPTCHYAYHPCDDAVMSLHEFNGKNFQMQSRQRLMRDEIVSGIDELG
HHEEECCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCHHHHC
VLLAGHKKNAYWYGSQLSIDEARALVPFNGATSLQVTSAALAGIVWALENPNAGVVESDE
EEEECCCCCCEEECCEECHHHCCEEEECCCCCCEEEHHHHHEEEEEEEECCCCCCEECCC
MDYRRNLEIMAPYLGPVVGEYTDWTPLYQRGELFPEDVDDDYAWQFKNVRV
CHHHCCCEEECHHHCCHHCCCCCCCHHHHCCCCCCCCCCCCCEEEECCCCC
>Mature Secondary Structure 
TEPIKYVKAPGRILIVGFGSIGQGLLPLILRHIDITPQKICIITADDRGREEAGKLGIR
CCCCHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCCEE
FIEMPLTRKNYQSELTPLVGKDDFLVNLSVDVSSIALVEFCQARGARYLDTCIEPWAGGY
EEECCCCCCCHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
TDPSKSFAARSNYALRERVLALKDKYRGGPTAVVAQGANPGMVSHLVKQALMNLQQDILG
CCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHC
TQSEPKSREEWAKLAHDLNIEVIHIAERDTQVANQAKAMDEFVNTWSCDGFVSEGAQPAE
CCCCCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHH
LGWGTHEKHFPRDAGRHEEGCGAAIYLKCPGATVKVRTWTPNYGHFHGFLITHNEAISIA
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCEEEEEEECCCEEEHH
DFFTLKQEGKLVYRPTCHYAYHPCDDAVMSLHEFNGKNFQMQSRQRLMRDEIVSGIDELG
HHEEECCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCHHHHC
VLLAGHKKNAYWYGSQLSIDEARALVPFNGATSLQVTSAALAGIVWALENPNAGVVESDE
EEEECCCCCCEEECCEECHHHCCEEEECCCCCCEEEHHHHHEEEEEEEECCCCCCEECCC
MDYRRNLEIMAPYLGPVVGEYTDWTPLYQRGELFPEDVDDDYAWQFKNVRV
CHHHCCCEEECHHHCCHHCCCCCCCHHHHCCCCCCCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8841401 [H]