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The map label for this gene is xerC

Identifier: 119776379

GI number: 119776379

Start: 3841932

End: 3842822

Strand: Reverse

Name: xerC

Synonym: Sama_3247

Alternate gene names: 119776379

Gene position: 3842822-3841932 (Counterclockwise)

Preceding gene: 119776380

Following gene: 119776378

Centisome position: 89.24

GC content: 56.9

Gene sequence:

>891_bases
ATGGCCGACCAAGCCAGCTGGCTGGAACGTTTTACCCGCTACCTTGCCACCGAGCGACAATTATCGCCCATGACAGTGCG
TAATTATCGCTTTGAGCTGGAACGCGCCGATACGCTACTGGGACAGCGAAGCTGGCAGCAGTTGAGTCGCCAGGACCTCA
GCGGTCTGATGGCCCGGCTGCATCGCCAGGGGCTGTCGCCGCGATCTCTTTCGCTTACCGCGTCGGCACTCAAGCAGTTT
GGTCAGTTTCTGTTAAAAGAGGGGCTGATAGACACCAACCCTGCGGCCACCCTCAGTGCACCGAAGCAGTCCAAAACCTT
GCCGAAAAACCTTGACCCTGATTCGGTCAATCACCTGCTGGATATTCCTCCGGAAGATGGCCTGGCACTGCGTGACAAAG
CCATTATGGAGCTCTTTTACTCCTGTGGCCTGCGTCTGGCCGAACTGGCGGCGCTGGATGTGAAAGACCTTGATCGCGAG
AGCCGGGAGGTGAGGGTTATTGGTAAAGGCAGCAAGGAGCGGATCCTGCCTGTGGGCAGTGTCGCGTTGGCGGCCATTGG
CGATTGGCTGAAGGTCAGGAATCAAATGCCTTGCCAGGACGATGCCTTGTTTGTGTCTAGCCGTGGCAGCAGGCTTTCCC
ATCGCAGTATTCAGGCGAGAATGGAGAAATGGGCGCAAATACAGGGGCTCAGCGTTGGAGTGCACCCTCACAAACTCAGG
CATTCCTTCGCGACGCACATGCTGGAGTCCAGTGGCGACTTGCGGGCTGTTCAGGAATTGTTGGGTCACGCCAATCTTGC
CACCACACAAATTTACACCAGTCTCGACTTTCAGCATCTGGCCAAGGTGTATGATGGCGCCCACCCTAGAGCGCGCAAAA
AGGGGGATTGA

Upstream 100 bases:

>100_bases
TCGCCAGTCAGGACCCGGCGCATTTTCATCCCGAGATGGACAACTTGCTGTTGGATCAACTACGGCGGATTTTGGACCAT
CTGCTGCCAAGGCTCTGATT

Downstream 100 bases:

>100_bases
TGCAGATATTTCGTCGCCTTAAGCCCATTGCCGCCATCAGTTTTGACCTGGACGACACCCTGTACGACAACCGCCCCGTG
ATTATGGCCGCGGAGCTGGC

Product: integrase/recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MADQASWLERFTRYLATERQLSPMTVRNYRFELERADTLLGQRSWQQLSRQDLSGLMARLHRQGLSPRSLSLTASALKQF
GQFLLKEGLIDTNPAATLSAPKQSKTLPKNLDPDSVNHLLDIPPEDGLALRDKAIMELFYSCGLRLAELAALDVKDLDRE
SREVRVIGKGSKERILPVGSVALAAIGDWLKVRNQMPCQDDALFVSSRGSRLSHRSIQARMEKWAQIQGLSVGVHPHKLR
HSFATHMLESSGDLRAVQELLGHANLATTQIYTSLDFQHLAKVYDGAHPRARKKGD

Sequences:

>Translated_296_residues
MADQASWLERFTRYLATERQLSPMTVRNYRFELERADTLLGQRSWQQLSRQDLSGLMARLHRQGLSPRSLSLTASALKQF
GQFLLKEGLIDTNPAATLSAPKQSKTLPKNLDPDSVNHLLDIPPEDGLALRDKAIMELFYSCGLRLAELAALDVKDLDRE
SREVRVIGKGSKERILPVGSVALAAIGDWLKVRNQMPCQDDALFVSSRGSRLSHRSIQARMEKWAQIQGLSVGVHPHKLR
HSFATHMLESSGDLRAVQELLGHANLATTQIYTSLDFQHLAKVYDGAHPRARKKGD
>Mature_295_residues
ADQASWLERFTRYLATERQLSPMTVRNYRFELERADTLLGQRSWQQLSRQDLSGLMARLHRQGLSPRSLSLTASALKQFG
QFLLKEGLIDTNPAATLSAPKQSKTLPKNLDPDSVNHLLDIPPEDGLALRDKAIMELFYSCGLRLAELAALDVKDLDRES
REVRVIGKGSKERILPVGSVALAAIGDWLKVRNQMPCQDDALFVSSRGSRLSHRSIQARMEKWAQIQGLSVGVHPHKLRH
SFATHMLESSGDLRAVQELLGHANLATTQIYTSLDFQHLAKVYDGAHPRARKKGD

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=296, Percent_Identity=54.7297297297297, Blast_Score=313, Evalue=9e-87,
Organism=Escherichia coli, GI1789261, Length=293, Percent_Identity=36.518771331058, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1790767, Length=167, Percent_Identity=27.5449101796407, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790768, Length=160, Percent_Identity=33.75, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_SHEAM (A1SAP3)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_929119.1
- ProteinModelPortal:   A1SAP3
- SMR:   A1SAP3
- STRING:   A1SAP3
- GeneID:   4605494
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_3247
- NMPDR:   fig|326297.7.peg.3059
- eggNOG:   COG4973
- HOGENOM:   HBG727654
- OMA:   TTEGIRD
- PhylomeDB:   A1SAP3
- ProtClustDB:   CLSK907582
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02224

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 33167; Mature: 33036

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: ACT_SITE 145-145 ACT_SITE 169-169 ACT_SITE 237-237 ACT_SITE 240-240 ACT_SITE 263-263 ACT_SITE 272-272

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADQASWLERFTRYLATERQLSPMTVRNYRFELERADTLLGQRSWQQLSRQDLSGLMARL
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRQGLSPRSLSLTASALKQFGQFLLKEGLIDTNPAATLSAPKQSKTLPKNLDPDSVNHLL
HHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHC
DIPPEDGLALRDKAIMELFYSCGLRLAELAALDVKDLDRESREVRVIGKGSKERILPVGS
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHH
VALAAIGDWLKVRNQMPCQDDALFVSSRGSRLSHRSIQARMEKWAQIQGLSVGVHPHKLR
HHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCEECCCHHHHH
HSFATHMLESSGDLRAVQELLGHANLATTQIYTSLDFQHLAKVYDGAHPRARKKGD
HHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ADQASWLERFTRYLATERQLSPMTVRNYRFELERADTLLGQRSWQQLSRQDLSGLMARL
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRQGLSPRSLSLTASALKQFGQFLLKEGLIDTNPAATLSAPKQSKTLPKNLDPDSVNHLL
HHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHC
DIPPEDGLALRDKAIMELFYSCGLRLAELAALDVKDLDRESREVRVIGKGSKERILPVGS
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHH
VALAAIGDWLKVRNQMPCQDDALFVSSRGSRLSHRSIQARMEKWAQIQGLSVGVHPHKLR
HHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCEECCCHHHHH
HSFATHMLESSGDLRAVQELLGHANLATTQIYTSLDFQHLAKVYDGAHPRARKKGD
HHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA