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The map label for this gene is ttdR [H]

Identifier: 119776350

GI number: 119776350

Start: 3810297

End: 3811256

Strand: Reverse

Name: ttdR [H]

Synonym: Sama_3218

Alternate gene names: 119776350

Gene position: 3811256-3810297 (Counterclockwise)

Preceding gene: 119776351

Following gene: 119776347

Centisome position: 88.51

GC content: 61.04

Gene sequence:

>960_bases
TTGCTGACCACAGATTTAGCACTGTTTGTTCGTGTGGCAGAGGCCGGCAGTATCAGTGCGGCTGCCACCGAACTGGATAT
GACGCCGGCATCGGCCAGCGCAGCCATCAAGCGGCTGGAAAAACAACTGGGCTCGCCGCTTTTTATCCGTACCACGCGCA
GTCTCAGGCTGTCACACGCCGGAGAACGGTATCTGGGCCATTGCCGCGAGGCTCTCAGCGCCCTTGAATTGGGCCGCATG
GCGCTGTCCAGTGAACGCGGCACTGTGGAAGGCACTCTGAGGATTTCGGTGTCGTCGGATTTTGGTCGTAATATCTTTTT
ACCCTGGCTCGATGAACTGATGGAACAGCACCCCGGACTTGAGGTGCAGCTGGAGCTGGGGGACAAGGTCAGCAGTCTGT
TTCGCAGCAATATCGACGTAGCACTGCGCTACGGTATGCCCCAGGACTCGGAGGCGGTGGCGTTCTCCCTTGGACACCTG
TCGCGCCAGCTTGCGGCCTCACCTCGGTATTTGGCCCGGGAGGGCACGCCGACAACCCCGGCCGAGTTAGCCGCCCACCA
ATGCCTGCTATACAAACGTGCCGATAAGACCCACGACCTGTGGCATTTTTTCAGCGGTAATGAAGAACACAAGGTACGTG
TCAGCGGCCGACGCAGCTGCAACGATGCCGAAATAGCGCGGCGCTGGGCGGTAGCGGGACTGGGGCTGGTGTATAAGTCG
CGGTTGGACTTGGCCGCTGACTTGCTCGATGGCCGCCTGGTGCCCCTGCTGCCGGATTATGGTACCGAGCCGCTGGAGCT
TTATTTGCTGTGCCCCGGACGGGCCCAGGTGACACCGGCGGTGTTGGCCCTGCGGGATATGTTAAGGACCCGGGTGGCCG
AACGTCTGGCCATGCTGGACAATTCGATGACGGCGGGTCCTCCGCCAGAGAATGCCGCCACCGATGAGGGATGGGGGTGA

Upstream 100 bases:

>100_bases
GCTGACCCAAGTAGCCCGCGCCGGATATTCCCGCGCGGGCTTTGTTTTAAGGGGCATTTGGGGGTAGTGTTAGCCGGTAA
ATATCAGGCGAGGATTGCAA

Downstream 100 bases:

>100_bases
GTCAGCGCCAAGGCTCACCCAGACCAGAAAGTTTCACGGGAATAAAAAAGCCGCTCATTGAGCGGCTTTTTTACGGGTTG
CTTTACCTGAATGCTTATTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MLTTDLALFVRVAEAGSISAAATELDMTPASASAAIKRLEKQLGSPLFIRTTRSLRLSHAGERYLGHCREALSALELGRM
ALSSERGTVEGTLRISVSSDFGRNIFLPWLDELMEQHPGLEVQLELGDKVSSLFRSNIDVALRYGMPQDSEAVAFSLGHL
SRQLAASPRYLAREGTPTTPAELAAHQCLLYKRADKTHDLWHFFSGNEEHKVRVSGRRSCNDAEIARRWAVAGLGLVYKS
RLDLAADLLDGRLVPLLPDYGTEPLELYLLCPGRAQVTPAVLALRDMLRTRVAERLAMLDNSMTAGPPPENAATDEGWG

Sequences:

>Translated_319_residues
MLTTDLALFVRVAEAGSISAAATELDMTPASASAAIKRLEKQLGSPLFIRTTRSLRLSHAGERYLGHCREALSALELGRM
ALSSERGTVEGTLRISVSSDFGRNIFLPWLDELMEQHPGLEVQLELGDKVSSLFRSNIDVALRYGMPQDSEAVAFSLGHL
SRQLAASPRYLAREGTPTTPAELAAHQCLLYKRADKTHDLWHFFSGNEEHKVRVSGRRSCNDAEIARRWAVAGLGLVYKS
RLDLAADLLDGRLVPLLPDYGTEPLELYLLCPGRAQVTPAVLALRDMLRTRVAERLAMLDNSMTAGPPPENAATDEGWG
>Mature_319_residues
MLTTDLALFVRVAEAGSISAAATELDMTPASASAAIKRLEKQLGSPLFIRTTRSLRLSHAGERYLGHCREALSALELGRM
ALSSERGTVEGTLRISVSSDFGRNIFLPWLDELMEQHPGLEVQLELGDKVSSLFRSNIDVALRYGMPQDSEAVAFSLGHL
SRQLAASPRYLAREGTPTTPAELAAHQCLLYKRADKTHDLWHFFSGNEEHKVRVSGRRSCNDAEIARRWAVAGLGLVYKS
RLDLAADLLDGRLVPLLPDYGTEPLELYLLCPGRAQVTPAVLALRDMLRTRVAERLAMLDNSMTAGPPPENAATDEGWG

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=260, Percent_Identity=35.3846153846154, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI145693193, Length=275, Percent_Identity=32.3636363636364, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=31.1864406779661, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1789639, Length=268, Percent_Identity=32.8358208955224, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1786401, Length=255, Percent_Identity=30.5882352941176, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787589, Length=289, Percent_Identity=27.3356401384083, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=27.1477663230241, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1786448, Length=293, Percent_Identity=24.9146757679181, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI157672245, Length=160, Percent_Identity=30.625, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788706, Length=295, Percent_Identity=23.0508474576271, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790011, Length=283, Percent_Identity=26.1484098939929, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789173, Length=289, Percent_Identity=25.2595155709343, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790208, Length=157, Percent_Identity=29.9363057324841, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787601, Length=178, Percent_Identity=28.0898876404494, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34962; Mature: 34962

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTTDLALFVRVAEAGSISAAATELDMTPASASAAIKRLEKQLGSPLFIRTTRSLRLSHA
CCCCHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHC
GERYLGHCREALSALELGRMALSSERGTVEGTLRISVSSDFGRNIFLPWLDELMEQHPGL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCEEEHHHHHHHHHHCCCC
EVQLELGDKVSSLFRSNIDVALRYGMPQDSEAVAFSLGHLSRQLAASPRYLAREGTPTTP
EEEEECCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCH
AELAAHQCLLYKRADKTHDLWHFFSGNEEHKVRVSGRRSCNDAEIARRWAVAGLGLVYKS
HHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
RLDLAADLLDGRLVPLLPDYGTEPLELYLLCPGRAQVTPAVLALRDMLRTRVAERLAMLD
HHHHHHHHHCCCEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
NSMTAGPPPENAATDEGWG
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLTTDLALFVRVAEAGSISAAATELDMTPASASAAIKRLEKQLGSPLFIRTTRSLRLSHA
CCCCHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHC
GERYLGHCREALSALELGRMALSSERGTVEGTLRISVSSDFGRNIFLPWLDELMEQHPGL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCEEEHHHHHHHHHHCCCC
EVQLELGDKVSSLFRSNIDVALRYGMPQDSEAVAFSLGHLSRQLAASPRYLAREGTPTTP
EEEEECCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCH
AELAAHQCLLYKRADKTHDLWHFFSGNEEHKVRVSGRRSCNDAEIARRWAVAGLGLVYKS
HHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
RLDLAADLLDGRLVPLLPDYGTEPLELYLLCPGRAQVTPAVLALRDMLRTRVAERLAMLD
HHHHHHHHHCCCEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
NSMTAGPPPENAATDEGWG
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]