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The map label for this gene is dctS [H]

Identifier: 119776314

GI number: 119776314

Start: 3773155

End: 3774984

Strand: Reverse

Name: dctS [H]

Synonym: Sama_3182

Alternate gene names: 119776314

Gene position: 3774984-3773155 (Counterclockwise)

Preceding gene: 119776317

Following gene: 119776309

Centisome position: 87.67

GC content: 57.7

Gene sequence:

>1830_bases
ATGAAGTCATTGCTGCTGTGTGTGTTATTGTGGCCCCTGTCGGTGTTGGCTACCGATGCCGAAATGGGGGATGAGCCCAT
TGAAGCCGTGTTCAGAGTCGGGGTACTTGCCAATCATGGGGTTGGTGAGGCGAAACAGCGCTGGCAACCCATGATGAACT
ATTTGTCGGACAGGGTGCCCGGCATTCGTTTTGAAGTCGAGCCGCTGGATTTTGATGCCATGCGCGAGCAGCTGTTGGAC
TTGCGTATCCAATTTATTGTGACCAATCCGGGCCAATATCTGAGCCTGTCCAACGAGATGCCTCTCTCTTGGCTTGCCAC
CATGCGCAGCCGCAAACACAACGGTGCCACCTATGCCATAGGCTCCACCATCATAGTGCGCAGCGACAGCCCTGTGCAGC
ATATCGAAGAGCTCGAAGGGGCCCGAATCGTGGCCTCCGATCCTCAGGCGCTCGGTGGCTATCAGGCCACCATTGGCCTG
TTGAATCGCCGCGGTTTGGATGCGCGCAACTTTTTTGCCGATGTGCGTTTTCTGGGGTTTCCATTGGAGCCGCTGGTGTA
TCAGGTGCGCGACGGCATGGTCGATGGCGCTATTACGCCTTACTGCACTCTGGAAGAAATGGTGGACTCGGGCCTGGTGC
GCCGGGAGGATTTTCGGGTGCTTAACAGCATGCGTCCGGAAGGCTATGACTGTGAAATCAGCACCAGTTTGTACCCCAAT
TGGTCCTTTGCCGCCTCCGATAAGGTACCCGCCCGCATCACCCAGATGGTCACCAAGGCGCTGTTTGAACTGCCCTCAGA
CTCAGAAGCCGCCATTCGGGCCCGCACCCTGGGCTGGACCGCCCCCATCAGCCAACTCACGGTTATTCGCCTCTATGAAG
AGCTTCTGCTCCATGGCAACAGCACCCGACCACTGGAGCTGGTGCGAGCCTGGCTTAAGGCCAATCTGGAATACGCCATC
AGTTTGGTGCTTATTCTGTTTGCCGGCATGGTTTACCACCTGTGGCTCGAATATAAGTTTCGCCAAAAGAGCGACAGCCT
GATAGCGGCCGAGCGCACCTTAAGGGACAGGGAACTCATGTTGGAGCGGATGCAAAGCGCCGCTATTTTGGGGGAGATAG
GCGCCGGGCTTGCCCATGAACTCAACCAGCCTATTGCCGCCATTACCCAATACAGCGAGGGTGGATTGATGGCGCTGAAG
CAGCAAGATCACGCCAGTGCCGAACTGCGTTTGCAGGCAGTGGAGGAGGTGCTTGGCAAAATTAATCGCCAGTCGATGCG
TGCCGGTGCCGTGGTGCATCGTATCCGCAGCCTGCTGCGCCGCCGTCGTGCCCGCCCGGAAGCCGTGCTGATGAGTTCCT
TGCTGAGTGAAGCCCTGGCCTTGTTTCAACGCTCCCTGGAGCAGCAGCGGGTGCAAGTGACACTGAAACAAGCGGGCGAA
GAGCGACCGCTGTTGGGGGACGCGGTGGGGTTGAGTCAGCTGCTGGTGAATCTGCTCAAAAATGCCCTTGATGCCATGGA
GGTCCGGTCTGAGGCTAGGCAAATTGATATCACGCTGGACTTTGATGCCAGCAAGCCCGGCAGTGCAGCCAGGGTGCGCT
GGCTGAGGCTGGAACTCCTGGACAATGGCAGCGGCCTTAAGGCCGAGGCGGCGGAGCTGATGCTCTCTTTTGCCACCACC
AAAGACGAAGGTTTGGGCCTGGGGCTTGCCATCTGTCGTGATGTGGTCAATCAACATGGAGGTGATATTCAGCTGCAAAA
CCGCCAGGACGGCAGCGGTTGCCGGGTCACTGTGTGGTTACCATTGCTGGCGGACGATGAGTCTGTATAA

Upstream 100 bases:

>100_bases
CTCGCTTTTGGCGATGGATCACGCAGGCGGCGTATTTTTTGCGGGGGGATTCACGTTGGCGCACGCGTGGCGCAGGCACA
ATATGCGGTGGAGGTATGGG

Downstream 100 bases:

>100_bases
GCTTTTATCAGCGACTCAGTCAAGCTGCCTCTGATTGAGCCACTGGCGGCGACCCAATTCCAGCAGCATGCCCACCGCTA
AGCCGGCTGCGGCATTGACT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MKSLLLCVLLWPLSVLATDAEMGDEPIEAVFRVGVLANHGVGEAKQRWQPMMNYLSDRVPGIRFEVEPLDFDAMREQLLD
LRIQFIVTNPGQYLSLSNEMPLSWLATMRSRKHNGATYAIGSTIIVRSDSPVQHIEELEGARIVASDPQALGGYQATIGL
LNRRGLDARNFFADVRFLGFPLEPLVYQVRDGMVDGAITPYCTLEEMVDSGLVRREDFRVLNSMRPEGYDCEISTSLYPN
WSFAASDKVPARITQMVTKALFELPSDSEAAIRARTLGWTAPISQLTVIRLYEELLLHGNSTRPLELVRAWLKANLEYAI
SLVLILFAGMVYHLWLEYKFRQKSDSLIAAERTLRDRELMLERMQSAAILGEIGAGLAHELNQPIAAITQYSEGGLMALK
QQDHASAELRLQAVEEVLGKINRQSMRAGAVVHRIRSLLRRRRARPEAVLMSSLLSEALALFQRSLEQQRVQVTLKQAGE
ERPLLGDAVGLSQLLVNLLKNALDAMEVRSEARQIDITLDFDASKPGSAARVRWLRLELLDNGSGLKAEAAELMLSFATT
KDEGLGLGLAICRDVVNQHGGDIQLQNRQDGSGCRVTVWLPLLADDESV

Sequences:

>Translated_609_residues
MKSLLLCVLLWPLSVLATDAEMGDEPIEAVFRVGVLANHGVGEAKQRWQPMMNYLSDRVPGIRFEVEPLDFDAMREQLLD
LRIQFIVTNPGQYLSLSNEMPLSWLATMRSRKHNGATYAIGSTIIVRSDSPVQHIEELEGARIVASDPQALGGYQATIGL
LNRRGLDARNFFADVRFLGFPLEPLVYQVRDGMVDGAITPYCTLEEMVDSGLVRREDFRVLNSMRPEGYDCEISTSLYPN
WSFAASDKVPARITQMVTKALFELPSDSEAAIRARTLGWTAPISQLTVIRLYEELLLHGNSTRPLELVRAWLKANLEYAI
SLVLILFAGMVYHLWLEYKFRQKSDSLIAAERTLRDRELMLERMQSAAILGEIGAGLAHELNQPIAAITQYSEGGLMALK
QQDHASAELRLQAVEEVLGKINRQSMRAGAVVHRIRSLLRRRRARPEAVLMSSLLSEALALFQRSLEQQRVQVTLKQAGE
ERPLLGDAVGLSQLLVNLLKNALDAMEVRSEARQIDITLDFDASKPGSAARVRWLRLELLDNGSGLKAEAAELMLSFATT
KDEGLGLGLAICRDVVNQHGGDIQLQNRQDGSGCRVTVWLPLLADDESV
>Mature_609_residues
MKSLLLCVLLWPLSVLATDAEMGDEPIEAVFRVGVLANHGVGEAKQRWQPMMNYLSDRVPGIRFEVEPLDFDAMREQLLD
LRIQFIVTNPGQYLSLSNEMPLSWLATMRSRKHNGATYAIGSTIIVRSDSPVQHIEELEGARIVASDPQALGGYQATIGL
LNRRGLDARNFFADVRFLGFPLEPLVYQVRDGMVDGAITPYCTLEEMVDSGLVRREDFRVLNSMRPEGYDCEISTSLYPN
WSFAASDKVPARITQMVTKALFELPSDSEAAIRARTLGWTAPISQLTVIRLYEELLLHGNSTRPLELVRAWLKANLEYAI
SLVLILFAGMVYHLWLEYKFRQKSDSLIAAERTLRDRELMLERMQSAAILGEIGAGLAHELNQPIAAITQYSEGGLMALK
QQDHASAELRLQAVEEVLGKINRQSMRAGAVVHRIRSLLRRRRARPEAVLMSSLLSEALALFQRSLEQQRVQVTLKQAGE
ERPLLGDAVGLSQLLVNLLKNALDAMEVRSEARQIDITLDFDASKPGSAARVRWLRLELLDNGSGLKAEAAELMLSFATT
KDEGLGLGLAICRDVVNQHGGDIQLQNRQDGSGCRVTVWLPLLADDESV

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=255, Percent_Identity=28.2352941176471, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1788549, Length=258, Percent_Identity=29.4573643410853, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67855; Mature: 67855

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLLLCVLLWPLSVLATDAEMGDEPIEAVFRVGVLANHGVGEAKQRWQPMMNYLSDRVP
CCHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
GIRFEVEPLDFDAMREQLLDLRIQFIVTNPGQYLSLSNEMPLSWLATMRSRKHNGATYAI
CCEEEECCCCHHHHHHHHHHEEEEEEEECCCCEEEECCCCCHHHHHHHHHCCCCCCEEEE
GSTIIVRSDSPVQHIEELEGARIVASDPQALGGYQATIGLLNRRGLDARNFFADVRFLGF
CCEEEEECCCHHHHHHHCCCCEEEECCCHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCC
PLEPLVYQVRDGMVDGAITPYCTLEEMVDSGLVRREDFRVLNSMRPEGYDCEISTSLYPN
CHHHHHHHHHCCCCCCCCCCCEEHHHHHHCCCCCHHHHHHHHCCCCCCCCEEEECCCCCC
WSFAASDKVPARITQMVTKALFELPSDSEAAIRARTLGWTAPISQLTVIRLYEELLLHGN
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
STRPLELVRAWLKANLEYAISLVLILFAGMVYHLWLEYKFRQKSDSLIAAERTLRDRELM
CCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LERMQSAAILGEIGAGLAHELNQPIAAITQYSEGGLMALKQQDHASAELRLQAVEEVLGK
HHHHHHHHHHHHHCCHHHHHHCCCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
INRQSMRAGAVVHRIRSLLRRRRARPEAVLMSSLLSEALALFQRSLEQQRVQVTLKQAGE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ERPLLGDAVGLSQLLVNLLKNALDAMEVRSEARQIDITLDFDASKPGSAARVRWLRLELL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHEEEEEEEEE
DNGSGLKAEAAELMLSFATTKDEGLGLGLAICRDVVNQHGGDIQLQNRQDGSGCRVTVWL
CCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEE
PLLADDESV
EEECCCCCC
>Mature Secondary Structure
MKSLLLCVLLWPLSVLATDAEMGDEPIEAVFRVGVLANHGVGEAKQRWQPMMNYLSDRVP
CCHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
GIRFEVEPLDFDAMREQLLDLRIQFIVTNPGQYLSLSNEMPLSWLATMRSRKHNGATYAI
CCEEEECCCCHHHHHHHHHHEEEEEEEECCCCEEEECCCCCHHHHHHHHHCCCCCCEEEE
GSTIIVRSDSPVQHIEELEGARIVASDPQALGGYQATIGLLNRRGLDARNFFADVRFLGF
CCEEEEECCCHHHHHHHCCCCEEEECCCHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCC
PLEPLVYQVRDGMVDGAITPYCTLEEMVDSGLVRREDFRVLNSMRPEGYDCEISTSLYPN
CHHHHHHHHHCCCCCCCCCCCEEHHHHHHCCCCCHHHHHHHHCCCCCCCCEEEECCCCCC
WSFAASDKVPARITQMVTKALFELPSDSEAAIRARTLGWTAPISQLTVIRLYEELLLHGN
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
STRPLELVRAWLKANLEYAISLVLILFAGMVYHLWLEYKFRQKSDSLIAAERTLRDRELM
CCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LERMQSAAILGEIGAGLAHELNQPIAAITQYSEGGLMALKQQDHASAELRLQAVEEVLGK
HHHHHHHHHHHHHCCHHHHHHCCCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
INRQSMRAGAVVHRIRSLLRRRRARPEAVLMSSLLSEALALFQRSLEQQRVQVTLKQAGE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ERPLLGDAVGLSQLLVNLLKNALDAMEVRSEARQIDITLDFDASKPGSAARVRWLRLELL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHEEEEEEEEE
DNGSGLKAEAAELMLSFATTKDEGLGLGLAICRDVVNQHGGDIQLQNRQDGSGCRVTVWL
CCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEE
PLLADDESV
EEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]