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The map label for this gene is plsC [H]

Identifier: 119776271

GI number: 119776271

Start: 3726934

End: 3727671

Strand: Reverse

Name: plsC [H]

Synonym: Sama_3139

Alternate gene names: 119776271

Gene position: 3727671-3726934 (Counterclockwise)

Preceding gene: 119776272

Following gene: 119776270

Centisome position: 86.57

GC content: 55.83

Gene sequence:

>738_bases
GTGCTGTTAATCGTCAGATCCTTGCTGTTGGCTATATTGCTGCTGATGGCATTCATCGTGGGTTCCATTGCCTGTTTGTT
GCGCCCAAGGCACCGTGACAATGTACATATGTTCGCCAAATGGTTCTCTGCCGTCGCGCCGGTATTGGGAATTAAGGTGA
TAGTGCGTCGTCCCCAGGCCGCCAGCAGTGAGCCTTGCGTCTACCTTGCCAACCATCAAAACAACTTTGACATGTTCACC
CATACCGCTGCCGTGCCTAAAGGTACTGTGAGCCTGGGGAAAAAGAGCATCGCCTGGATGCCATTCTTCGGCCAAATATA
CTGGTTGTCGGGCAATATCCTTATTGATCGTAAAAACCGTAACCGCGCCTTTGAGACCATGGCCAACACCGCCAGAAAAA
TCAAAGATAAGTGCCTGTCGGTGTGGATTTTCCCCGAAGGTACCCGCAGTCGTGGCCGGGGGCTCCTGCCATTCAAGGCC
GGGGCTTTCCACACGGCGATCGCCGCCGGTGTGCCCATGGTGCCAGTGCTGGCCTCCAACCAGTGCCACATCAAACTCAA
TCGCTGGAATAATGGCGTGGTGATCATCGAGCAGATGGAACCCTTTGAGACCAAGGGGCTGGACAAGAGTCAGGTCAAGG
AACTGTCTGAGCGCATCCACGCCGCCATGTCGGCCAGGCTTGAGCAGCTTAACCGCGAGGCCGACGCCCTGATGGGCCGA
GCCCGTCTGGCCAACTGA

Upstream 100 bases:

>100_bases
TAATGATTAATTAATAAATCAGCGCACACGTGTAAACAAAATATTGTTCCCGTCATACTCTGTCGTTATACTGCGCAGGA
GTTTTTACCGGGAGTATGTC

Downstream 100 bases:

>100_bases
CGCCTTTTTTAATCTCTGTTATACTGCGCCCTGATTGCGCCTCCCGTGGTGGGCAGGCGCTTGCTTTGTTTATTGGAGTC
AGCCCATGTCTATTGAGCGC

Product: 1-acylglycerol-3-phosphate O-acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MLLIVRSLLLAILLLMAFIVGSIACLLRPRHRDNVHMFAKWFSAVAPVLGIKVIVRRPQAASSEPCVYLANHQNNFDMFT
HTAAVPKGTVSLGKKSIAWMPFFGQIYWLSGNILIDRKNRNRAFETMANTARKIKDKCLSVWIFPEGTRSRGRGLLPFKA
GAFHTAIAAGVPMVPVLASNQCHIKLNRWNNGVVIIEQMEPFETKGLDKSQVKELSERIHAAMSARLEQLNREADALMGR
ARLAN

Sequences:

>Translated_245_residues
MLLIVRSLLLAILLLMAFIVGSIACLLRPRHRDNVHMFAKWFSAVAPVLGIKVIVRRPQAASSEPCVYLANHQNNFDMFT
HTAAVPKGTVSLGKKSIAWMPFFGQIYWLSGNILIDRKNRNRAFETMANTARKIKDKCLSVWIFPEGTRSRGRGLLPFKA
GAFHTAIAAGVPMVPVLASNQCHIKLNRWNNGVVIIEQMEPFETKGLDKSQVKELSERIHAAMSARLEQLNREADALMGR
ARLAN
>Mature_245_residues
MLLIVRSLLLAILLLMAFIVGSIACLLRPRHRDNVHMFAKWFSAVAPVLGIKVIVRRPQAASSEPCVYLANHQNNFDMFT
HTAAVPKGTVSLGKKSIAWMPFFGQIYWLSGNILIDRKNRNRAFETMANTARKIKDKCLSVWIFPEGTRSRGRGLLPFKA
GAFHTAIAAGVPMVPVLASNQCHIKLNRWNNGVVIIEQMEPFETKGLDKSQVKELSERIHAAMSARLEQLNREADALMGR
ARLAN

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=214, Percent_Identity=30.8411214953271, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI15100175, Length=214, Percent_Identity=30.8411214953271, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI6041665, Length=230, Percent_Identity=30.8695652173913, Blast_Score=119, Evalue=2e-27,
Organism=Escherichia coli, GI1789395, Length=235, Percent_Identity=47.6595744680851, Blast_Score=235, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17564032, Length=225, Percent_Identity=34.2222222222222, Blast_Score=127, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17568319, Length=238, Percent_Identity=28.5714285714286, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320151, Length=243, Percent_Identity=31.2757201646091, Blast_Score=127, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24641614, Length=218, Percent_Identity=33.9449541284404, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24641612, Length=218, Percent_Identity=33.9449541284404, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI281364648, Length=249, Percent_Identity=27.3092369477912, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24582856, Length=249, Percent_Identity=27.3092369477912, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24582854, Length=249, Percent_Identity=27.3092369477912, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27401; Mature: 27401

Theoretical pI: Translated: 11.12; Mature: 11.12

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLIVRSLLLAILLLMAFIVGSIACLLRPRHRDNVHMFAKWFSAVAPVLGIKVIVRRPQA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCC
ASSEPCVYLANHQNNFDMFTHTAAVPKGTVSLGKKSIAWMPFFGQIYWLSGNILIDRKNR
CCCCCEEEEECCCCCCCHHEECCCCCCCHHHHCCCCEEECCCCCEEEEEECCEEEECCCC
NRAFETMANTARKIKDKCLSVWIFPEGTRSRGRGLLPFKAGAFHTAIAAGVPMVPVLASN
CHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECC
QCHIKLNRWNNGVVIIEQMEPFETKGLDKSQVKELSERIHAAMSARLEQLNREADALMGR
CEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARLAN
HHCCC
>Mature Secondary Structure
MLLIVRSLLLAILLLMAFIVGSIACLLRPRHRDNVHMFAKWFSAVAPVLGIKVIVRRPQA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCC
ASSEPCVYLANHQNNFDMFTHTAAVPKGTVSLGKKSIAWMPFFGQIYWLSGNILIDRKNR
CCCCCEEEEECCCCCCCHHEECCCCCCCHHHHCCCCEEECCCCCEEEEEECCEEEECCCC
NRAFETMANTARKIKDKCLSVWIFPEGTRSRGRGLLPFKAGAFHTAIAAGVPMVPVLASN
CHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECC
QCHIKLNRWNNGVVIIEQMEPFETKGLDKSQVKELSERIHAAMSARLEQLNREADALMGR
CEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARLAN
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1557036; 9278503 [H]