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The map label for this gene is adrA [H]

Identifier: 119776102

GI number: 119776102

Start: 3535999

End: 3537672

Strand: Direct

Name: adrA [H]

Synonym: Sama_2970

Alternate gene names: 119776102

Gene position: 3535999-3537672 (Clockwise)

Preceding gene: 119776100

Following gene: 119776106

Centisome position: 82.12

GC content: 56.93

Gene sequence:

>1674_bases
ATGAGTTTGCAACAAGCGCTGGGGTTGTTGGCGCTGGTGCTGTTTTCGCTGTTTGCCCACGCCCAGCCACTCACACCGGA
CGAACTGCCCGGGGATCCCCTGTCCCGGGAGTGGATGTATTTCATTGAGTCCGATAGGCGCATGAGCCCAGTTGACGCCA
AAGCCGCCTTCGAGCGTGGACGTTTTGCACCCCATGGCAAAAAGATACCCAGTTTGGGGATAGGTGCCCCACCGCTTTGG
CTGGCGCTGCCGTTACAAAACCCGTCCAATACTGACGTTCAGCTCATTTTCGAGCTCGCCAATGCCTGGCAGGATGAATT
GGCACTCTATCTGTTTGACCAAAGCGATCGCATGCAGGCCTGGTACGGTGGCGATGTGAATGCCAGGGCGGAAGATGGAC
GTTTTATGCGCCAGTCTCTGTGGCTGCCCCCGGGCAATCACCTGCTCCTGCTCCGGGTGTCAGGTCCCGATCCCAGGTTG
GTCCCCGTTTATCTGACTAGCCCACAGCAAGCCAACCTGCGTAATCGCATAGAACTGCTCAGCTACGGATTTCTCTATGG
TGGCCTCTTTGCACTCCTGGGGTACAACTTTATCCTCTTTCTGGGCATAGGCAGGCGTAGCTACTTTTATTACTCGTTGT
TTTTATTCAGCTTTATTCTGCTTAATCTGAGCTATACCGGCCATGGTCAGTTCTGGTTCTGGCCCGGGCTGTCCCACTGG
CGCCAATGGTCACACCCCATGTTAATGACGCTTTACTGCGTGTCCGGGCTGATGTTTGCGCTGCGTTTTTTGGGTATCGA
CAAGCTGCGCCCCCATCTGAGCTACATAGTACTGGGATTGGCGGTGCTGATGATGACGGTCCAGGGCGTGGCCATGACCA
CCGACGATCGCGAACTTGGACTCATCTTCGCCTTCGACTTTGTGTATATCTTTACCTTGCTGATGCCCCTCTTGGGCATA
CTCGCCTGGCTCCACGGGTTACCCACCGCCAGGCTGTTTTTGTTGGCGTCCCTGTCGACCATGGTAGGCAGCTGCACAAC
GGGACTGGCGGTTGAAGGCTATATCAGTTTCAACCAGTGGACTTACCGTGCGGCCGAAATAGGCATGTTTATCGACGCCA
TGTTGCTGGCACTGGCACTGGCGGCCCAGTTTCGCCAGTCAGAGCAGGAGCGCGTACTGGCCCAGCAGCTGGCGGCCACC
GATCCCCTTACCGGTATTGCCAACCGGCGTGCCTTCAGTGAGCAATTGCAGCGACTGTGGCACCTCGACAGCCAGCGTCG
CTGTCGGGCGCTGATCATGATAGACATCGACAGGTTCAAATCCATTAACGATACCCTGGGCCATGAGGTGGGCGACAAGG
TACTGACCGACATTGCCCGGGTAATACGCTACTCGATACGCAACCGGGACCAGTGTGGCCGCTGGGGCGGTGAGGAGTTT
GTGGTCCTGCTGGCCTCTGCCAGCGAAGAGGAAGCCGGCATTATCGCCGAGCGTATCCGCCATAATATCGAAAGTCTGAG
TTTTCCGGCGCCTGCCAACAAGCTTAAGGTCACCGCCAGTGTGGGCGTGTGTCTGGATGAGGGACACAGCCGCCACGAAG
ATATTTTGCGGCGTGCCGACGAGGCCATGTATCACGCCAAGGATGCGGGCGGGAACAGGGTTAAACTCGCCTAA

Upstream 100 bases:

>100_bases
TCACAGCAAAACCTTTACCGAACAGGTGTAGGTAAAATTATACAAACTACCCATAAATCATTACTATATTTAACCTGATG
TCACCACCCAAGGCGAATAG

Downstream 100 bases:

>100_bases
GCCCGGGGCGCACCTTAAACAAAAAGCCCGGCGATGCCGGGCTTTTTATCAGGGTGATACTCGCTGAATCTGTGTTAACC
ACCGATAATTTTTTGCCACC

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MSLQQALGLLALVLFSLFAHAQPLTPDELPGDPLSREWMYFIESDRRMSPVDAKAAFERGRFAPHGKKIPSLGIGAPPLW
LALPLQNPSNTDVQLIFELANAWQDELALYLFDQSDRMQAWYGGDVNARAEDGRFMRQSLWLPPGNHLLLLRVSGPDPRL
VPVYLTSPQQANLRNRIELLSYGFLYGGLFALLGYNFILFLGIGRRSYFYYSLFLFSFILLNLSYTGHGQFWFWPGLSHW
RQWSHPMLMTLYCVSGLMFALRFLGIDKLRPHLSYIVLGLAVLMMTVQGVAMTTDDRELGLIFAFDFVYIFTLLMPLLGI
LAWLHGLPTARLFLLASLSTMVGSCTTGLAVEGYISFNQWTYRAAEIGMFIDAMLLALALAAQFRQSEQERVLAQQLAAT
DPLTGIANRRAFSEQLQRLWHLDSQRRCRALIMIDIDRFKSINDTLGHEVGDKVLTDIARVIRYSIRNRDQCGRWGGEEF
VVLLASASEEEAGIIAERIRHNIESLSFPAPANKLKVTASVGVCLDEGHSRHEDILRRADEAMYHAKDAGGNRVKLA

Sequences:

>Translated_557_residues
MSLQQALGLLALVLFSLFAHAQPLTPDELPGDPLSREWMYFIESDRRMSPVDAKAAFERGRFAPHGKKIPSLGIGAPPLW
LALPLQNPSNTDVQLIFELANAWQDELALYLFDQSDRMQAWYGGDVNARAEDGRFMRQSLWLPPGNHLLLLRVSGPDPRL
VPVYLTSPQQANLRNRIELLSYGFLYGGLFALLGYNFILFLGIGRRSYFYYSLFLFSFILLNLSYTGHGQFWFWPGLSHW
RQWSHPMLMTLYCVSGLMFALRFLGIDKLRPHLSYIVLGLAVLMMTVQGVAMTTDDRELGLIFAFDFVYIFTLLMPLLGI
LAWLHGLPTARLFLLASLSTMVGSCTTGLAVEGYISFNQWTYRAAEIGMFIDAMLLALALAAQFRQSEQERVLAQQLAAT
DPLTGIANRRAFSEQLQRLWHLDSQRRCRALIMIDIDRFKSINDTLGHEVGDKVLTDIARVIRYSIRNRDQCGRWGGEEF
VVLLASASEEEAGIIAERIRHNIESLSFPAPANKLKVTASVGVCLDEGHSRHEDILRRADEAMYHAKDAGGNRVKLA
>Mature_556_residues
SLQQALGLLALVLFSLFAHAQPLTPDELPGDPLSREWMYFIESDRRMSPVDAKAAFERGRFAPHGKKIPSLGIGAPPLWL
ALPLQNPSNTDVQLIFELANAWQDELALYLFDQSDRMQAWYGGDVNARAEDGRFMRQSLWLPPGNHLLLLRVSGPDPRLV
PVYLTSPQQANLRNRIELLSYGFLYGGLFALLGYNFILFLGIGRRSYFYYSLFLFSFILLNLSYTGHGQFWFWPGLSHWR
QWSHPMLMTLYCVSGLMFALRFLGIDKLRPHLSYIVLGLAVLMMTVQGVAMTTDDRELGLIFAFDFVYIFTLLMPLLGIL
AWLHGLPTARLFLLASLSTMVGSCTTGLAVEGYISFNQWTYRAAEIGMFIDAMLLALALAAQFRQSEQERVLAQQLAATD
PLTGIANRRAFSEQLQRLWHLDSQRRCRALIMIDIDRFKSINDTLGHEVGDKVLTDIARVIRYSIRNRDQCGRWGGEEFV
VLLASASEEEAGIIAERIRHNIESLSFPAPANKLKVTASVGVCLDEGHSRHEDILRRADEAMYHAKDAGGNRVKLA

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=297, Percent_Identity=31.6498316498317, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=41.2121212121212, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1788085, Length=172, Percent_Identity=37.2093023255814, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI145693134, Length=158, Percent_Identity=36.7088607594937, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87081881, Length=195, Percent_Identity=35.8974358974359, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788381, Length=173, Percent_Identity=35.2601156069364, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI87082007, Length=158, Percent_Identity=41.1392405063291, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87081974, Length=155, Percent_Identity=32.9032258064516, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787802, Length=160, Percent_Identity=33.75, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788956, Length=149, Percent_Identity=37.5838926174497, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1787541, Length=173, Percent_Identity=32.3699421965318, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081977, Length=195, Percent_Identity=31.2820512820513, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1787056, Length=151, Percent_Identity=29.8013245033113, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 62883; Mature: 62752

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQQALGLLALVLFSLFAHAQPLTPDELPGDPLSREWMYFIESDRRMSPVDAKAAFERG
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHEEECCCCCCCCHHHHHHHCC
RFAPHGKKIPSLGIGAPPLWLALPLQNPSNTDVQLIFELANAWQDELALYLFDQSDRMQA
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCEEE
WYGGDVNARAEDGRFMRQSLWLPPGNHLLLLRVSGPDPRLVPVYLTSPQQANLRNRIELL
EECCCCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHH
SYGFLYGGLFALLGYNFILFLGIGRRSYFYYSLFLFSFILLNLSYTGHGQFWFWPGLSHW
HHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHH
RQWSHPMLMTLYCVSGLMFALRFLGIDKLRPHLSYIVLGLAVLMMTVQGVAMTTDDRELG
HHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCH
LIFAFDFVYIFTLLMPLLGILAWLHGLPTARLFLLASLSTMVGSCTTGLAVEGYISFNQW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCH
TYRAAEIGMFIDAMLLALALAAQFRQSEQERVLAQQLAATDPLTGIANRRAFSEQLQRLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
HLDSQRRCRALIMIDIDRFKSINDTLGHEVGDKVLTDIARVIRYSIRNRDQCGRWGGEEF
CCCCCCCCEEEEEEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEE
VVLLASASEEEAGIIAERIRHNIESLSFPAPANKLKVTASVGVCLDEGHSRHEDILRRAD
EEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHH
EAMYHAKDAGGNRVKLA
HHHHHHHCCCCCEEECC
>Mature Secondary Structure 
SLQQALGLLALVLFSLFAHAQPLTPDELPGDPLSREWMYFIESDRRMSPVDAKAAFERG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHEEECCCCCCCCHHHHHHHCC
RFAPHGKKIPSLGIGAPPLWLALPLQNPSNTDVQLIFELANAWQDELALYLFDQSDRMQA
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCEEE
WYGGDVNARAEDGRFMRQSLWLPPGNHLLLLRVSGPDPRLVPVYLTSPQQANLRNRIELL
EECCCCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHH
SYGFLYGGLFALLGYNFILFLGIGRRSYFYYSLFLFSFILLNLSYTGHGQFWFWPGLSHW
HHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHH
RQWSHPMLMTLYCVSGLMFALRFLGIDKLRPHLSYIVLGLAVLMMTVQGVAMTTDDRELG
HHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCH
LIFAFDFVYIFTLLMPLLGILAWLHGLPTARLFLLASLSTMVGSCTTGLAVEGYISFNQW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCH
TYRAAEIGMFIDAMLLALALAAQFRQSEQERVLAQQLAATDPLTGIANRRAFSEQLQRLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
HLDSQRRCRALIMIDIDRFKSINDTLGHEVGDKVLTDIARVIRYSIRNRDQCGRWGGEEF
CCCCCCCCEEEEEEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEE
VVLLASASEEEAGIIAERIRHNIESLSFPAPANKLKVTASVGVCLDEGHSRHEDILRRAD
EEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHH
EAMYHAKDAGGNRVKLA
HHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]