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The map label for this gene is surA [H]

Identifier: 119775949

GI number: 119775949

Start: 3356275

End: 3357579

Strand: Direct

Name: surA [H]

Synonym: Sama_2817

Alternate gene names: 119775949

Gene position: 3356275-3357579 (Clockwise)

Preceding gene: 119775948

Following gene: 119775950

Centisome position: 77.94

GC content: 53.49

Gene sequence:

>1305_bases
ATGAAACCCTGTAAGAAATTGATTTTTGCCGCTCTGGCCATGACCATGGGCTTCCAGAGCTTAGCTGCACCCCAACCCCT
GGATCGCGTTGCCGTGCAGGTGAACGACGGTATTGTGCTGGAAAGCGAAATCCAGAACATGATGGATACCGTAAAGAAAA
ACGCGTTAGCGGCTGGCCAGACGCTGCCTTCTGACGATGCCCTGCGCACCCAGGTAATTGAGCGTCTTATCCTGACTCGC
CTGCAATTGCAGATGGCCGAACGCGTCGGTCTGCATATTGGTGATTTGCAACTGGATCAGGCCATCGAAAATATCGCCCG
CGAACAGAAAATGACAGTAGCTCAGATGCAACAGGCTATTCAGGCCGAAGGCATGAGCTTTGCCCAGTACCGCGAGCAGC
TGCGCGAAGAAATCACCCTCGGTGAAATCCAGCGTATTCAGGTACAGCGTCGTATCCAGGTTTCTCCTCAGGAAATCAAC
AACCTGGTGAAGATGATTGAAGAACAGGGCAACAAGGACGTGGAATATCAGATTGGTCACATCCTGATTGAAGTACCCAG
CAATCCCACCAGTGCCGAGCTGGAGTCCGCCAGCAAGCGTGCTCAGGCCGTTATGGATCGCCTGAACAGCGGCAACGATT
TCCGTTCAATCGCCATTGCCGCCTCGTCCGGCCCCAAGGCGCTGGAAGGCGGTGTTTGGGATTATATGAACATCAACGAA
ATGCCGACCCTGTTTGCGGAAGTGATTGGTGATGCAAAGAAAGATGCCATCATAGGTCCTATCAAGAGTGGCTCCGGTTT
CCATATCCTGAAAATCATGGATATCCGCGGCCTGCAAACCCGTGAAATCGAAGAAGTGCGTGCCCGTCATATATTGCTGA
AGCCGTCACCAATCCTTTCTGAGGAGCGCGCCAAGGCCATGCTGGACCAGTTCGTCACCCAGATTAAGAGCGGTGAAGCC
AAGTTTGCCGATATCGCCCGCCAGTATTCTGAAGACCCCGGTTCTGCCACCAAGGGCGGTGAGCTGGGTTGGGCGGAGCC
CAACATCTATGTGCCTGAATTCGCACAGATGCTCGGTCAGTTAAGCCTGGATGAAATCAGCGCACCGTTTCGCACTGCCC
ACGGCTGGCACATAGTGCAGCTGGAAGAAAAGCGCAAAACAGACGCCACCGAGAAGTTCAACACCAACCGTGCGCATCAG
CTGATTTTCCGCCGTAAATTCAACGAGGAGCTGCAAGGCTGGCTCGATGAAATTCGCAGTGAAGCCCATATCGATGTGTG
GGAAGCCGAAGCTAACCGAGGTTAA

Upstream 100 bases:

>100_bases
AAACCACATTCAGGACGCGTTGTCCAAACAGGTTAACACTGCCGGGTTTTCTGTGCCGGTGAGGTGGAAGAAAACCGAAA
AACGCCAAGGATTTATTTGG

Downstream 100 bases:

>100_bases
TCACAGTGACAGTGAAACGCATAGCCATCACCCCCGGAGAGCCTGCCGGTATAGGCCCAGATCTGGTTATTCAGCTTGCC
CAGCAAGCCTGGCCGGTACA

Product: survival protein surA

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKPCKKLIFAALAMTMGFQSLAAPQPLDRVAVQVNDGIVLESEIQNMMDTVKKNALAAGQTLPSDDALRTQVIERLILTR
LQLQMAERVGLHIGDLQLDQAIENIAREQKMTVAQMQQAIQAEGMSFAQYREQLREEITLGEIQRIQVQRRIQVSPQEIN
NLVKMIEEQGNKDVEYQIGHILIEVPSNPTSAELESASKRAQAVMDRLNSGNDFRSIAIAASSGPKALEGGVWDYMNINE
MPTLFAEVIGDAKKDAIIGPIKSGSGFHILKIMDIRGLQTREIEEVRARHILLKPSPILSEERAKAMLDQFVTQIKSGEA
KFADIARQYSEDPGSATKGGELGWAEPNIYVPEFAQMLGQLSLDEISAPFRTAHGWHIVQLEEKRKTDATEKFNTNRAHQ
LIFRRKFNEELQGWLDEIRSEAHIDVWEAEANRG

Sequences:

>Translated_434_residues
MKPCKKLIFAALAMTMGFQSLAAPQPLDRVAVQVNDGIVLESEIQNMMDTVKKNALAAGQTLPSDDALRTQVIERLILTR
LQLQMAERVGLHIGDLQLDQAIENIAREQKMTVAQMQQAIQAEGMSFAQYREQLREEITLGEIQRIQVQRRIQVSPQEIN
NLVKMIEEQGNKDVEYQIGHILIEVPSNPTSAELESASKRAQAVMDRLNSGNDFRSIAIAASSGPKALEGGVWDYMNINE
MPTLFAEVIGDAKKDAIIGPIKSGSGFHILKIMDIRGLQTREIEEVRARHILLKPSPILSEERAKAMLDQFVTQIKSGEA
KFADIARQYSEDPGSATKGGELGWAEPNIYVPEFAQMLGQLSLDEISAPFRTAHGWHIVQLEEKRKTDATEKFNTNRAHQ
LIFRRKFNEELQGWLDEIRSEAHIDVWEAEANRG
>Mature_434_residues
MKPCKKLIFAALAMTMGFQSLAAPQPLDRVAVQVNDGIVLESEIQNMMDTVKKNALAAGQTLPSDDALRTQVIERLILTR
LQLQMAERVGLHIGDLQLDQAIENIAREQKMTVAQMQQAIQAEGMSFAQYREQLREEITLGEIQRIQVQRRIQVSPQEIN
NLVKMIEEQGNKDVEYQIGHILIEVPSNPTSAELESASKRAQAVMDRLNSGNDFRSIAIAASSGPKALEGGVWDYMNINE
MPTLFAEVIGDAKKDAIIGPIKSGSGFHILKIMDIRGLQTREIEEVRARHILLKPSPILSEERAKAMLDQFVTQIKSGEA
KFADIARQYSEDPGSATKGGELGWAEPNIYVPEFAQMLGQLSLDEISAPFRTAHGWHIVQLEEKRKTDATEKFNTNRAHQ
LIFRRKFNEELQGWLDEIRSEAHIDVWEAEANRG

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=427, Percent_Identity=43.0913348946136, Blast_Score=364, Evalue=1e-102,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 48674; Mature: 48674

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPCKKLIFAALAMTMGFQSLAAPQPLDRVAVQVNDGIVLESEIQNMMDTVKKNALAAGQ
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEECCCEEEHHHHHHHHHHHHHHHHHCCC
TLPSDDALRTQVIERLILTRLQLQMAERVGLHIGDLQLDQAIENIAREQKMTVAQMQQAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHHHHHHH
QAEGMSFAQYREQLREEITLGEIQRIQVQRRIQVSPQEINNLVKMIEEQGNKDVEYQIGH
HHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEE
ILIEVPSNPTSAELESASKRAQAVMDRLNSGNDFRSIAIAASSGPKALEGGVWDYMNINE
EEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHCCCCCCCCCCCH
MPTLFAEVIGDAKKDAIIGPIKSGSGFHILKIMDIRGLQTREIEEVRARHILLKPSPILS
HHHHHHHHHCCCCCCCEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHEEEECCCCCCH
EERAKAMLDQFVTQIKSGEAKFADIARQYSEDPGSATKGGELGWAEPNIYVPEFAQMLGQ
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCC
LSLDEISAPFRTAHGWHIVQLEEKRKTDATEKFNTNRAHQLIFRRKFNEELQGWLDEIRS
CCHHHHCCCHHCCCCEEEEEEHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
EAHIDVWEAEANRG
CCCCEEEECCCCCC
>Mature Secondary Structure
MKPCKKLIFAALAMTMGFQSLAAPQPLDRVAVQVNDGIVLESEIQNMMDTVKKNALAAGQ
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEECCCEEEHHHHHHHHHHHHHHHHHCCC
TLPSDDALRTQVIERLILTRLQLQMAERVGLHIGDLQLDQAIENIAREQKMTVAQMQQAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHHHHHHH
QAEGMSFAQYREQLREEITLGEIQRIQVQRRIQVSPQEINNLVKMIEEQGNKDVEYQIGH
HHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEE
ILIEVPSNPTSAELESASKRAQAVMDRLNSGNDFRSIAIAASSGPKALEGGVWDYMNINE
EEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHCCCCCCCCCCCH
MPTLFAEVIGDAKKDAIIGPIKSGSGFHILKIMDIRGLQTREIEEVRARHILLKPSPILS
HHHHHHHHHCCCCCCCEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHEEEECCCCCCH
EERAKAMLDQFVTQIKSGEAKFADIARQYSEDPGSATKGGELGWAEPNIYVPEFAQMLGQ
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCC
LSLDEISAPFRTAHGWHIVQLEEKRKTDATEKFNTNRAHQLIFRRKFNEELQGWLDEIRS
CCHHHHCCCHHCCCCEEEEEEHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
EAHIDVWEAEANRG
CCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]