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The map label for this gene is lptD [H]

Identifier: 119775948

GI number: 119775948

Start: 3353858

End: 3356152

Strand: Direct

Name: lptD [H]

Synonym: Sama_2816

Alternate gene names: 119775948

Gene position: 3353858-3356152 (Clockwise)

Preceding gene: 119775942

Following gene: 119775949

Centisome position: 77.89

GC content: 53.81

Gene sequence:

>2295_bases
ATGCAGATCCGTTACATATTGGCCCTCGGCCTGCTTCCCTGTCAGGCTATGGCCAACGATGCCGTGCCTGAGCCCGCCCC
GGATCAATGTCTGGTGGCGCCTCCCATTCCATTGCCAAGTGCACCGCAGTCAGCCTCAGCCGAAGAACAGGTAGAAATCC
GCTCTGTGTCTTCTGACGCCGTGATGAATCAAAACGCCACGTTCGAAGGCGACGTACAATTCCGTCAGGGCAATCGTTCC
ATCTCCGCAGACCGTGCGAACATGGATTACGAAAAACAGCAGTTGAATGCCGAAGGCAATCTGGTATTTCAGGACAGCCA
GTTTACCGTTACCGCCGACAATCTCAGCGCCAAAATCAAAGACAACAGCGCCACGCTGAACGGCGCACAGTATTGGCTGC
ACGGCCAGCAGGTTCACGGTAATGCCCGCAAGCTTGAGATAACCAAAGACAATAACCTCATTCTCAGTGGCACCGACTTT
ACCACCTGCCCGCCGGGTGACAGCTCCTGGCTGCTGGAAGCCGAACGGATCAAGATTGACTCCAGCGAAGAGTGGGGCGA
GATCTGGAATGCCAAGATGCGCATTGCCGATATCCCGGTATTCTATGTCCCCTACATGACGGTGCCGGTCTCGGACAAGC
GAAAAACCGGTTTCCTGTTCCCACAATTCAGCACCAGCACCACCAACGGCGTGGAAATCGCCACGCCCTGGTACTGGAAT
ATTGCCCCCGAATACGACCTGACCCTGACGCCGCACTACATGTCGGCGCGAGGGCTGTATCTGCAGAGTGAGTTTCGTTA
TCTCGCGGGTGATGCTCAGGCTGGCCGGGTAAATCTGGAATACCTCGGCAGCGATCGTCTGCTGGAAAACAGCGACGACC
GTTACCTGTATCACTGGGAACACAGGGGCGCCATCGACAAACATTGGCGCGTCAATGCGGCCTTCACCGATGTTTCCGAT
AATAACTACTTTAACGATCTGGATTCTGAAGTTGCCAGGGCAACGGATAACCAGCTGTCCCGCATCGGCGAAATGAGTTA
TTTCGAAAACGACTGGAATATCAGTGCCCGGGTTCAGGACATCAAGGTACTGGGTGAGGACGAAGTGCCTTATCAGGTGA
TGCCACAGTTAAGTTTTAACTACCGCAGCCAGGATTTACTCAACACACTCGAGTTCAGTTTTTTCGGCGAAGCCACCAAC
TTTGAGCACAAAGAACAAGACCAGGTCACTGCCACCCGGCTGCACCTGCAGCCCACCTTGAGTTTGCCCATTCACGGGCC
AGCCGGTTCGTTAACCAGCGAGTTAACCCTGCTGCAAACCAACTACTGGCAACGTAACACCGATTTGATGCCAGACTCTG
AACTGAACAGTTCCGTCAGCCGCACCCTGCCAAGAGCCAAGGTGCACGGTCAGATCAATCTGGAGCGCAATACCCAGTGG
TTGGGTGAATCCTACCGTCAAACCCTGGAGCCTCAGGTCCAATATTTGTATGTGGGTTACGAAGATCAGGATGATATCGG
TATCTACGACAGCGCCAGATTGCAGGACGACTACTATGGTCTGTTCCGCGCACGCCGCTTCTCCGGTCTGGACCGTATCT
CCGATGCCAACCAGCTGACACTGGGGTTGACCACCCGTTTCTTCGATGACCGCAACCAGGAACAGTTCAAGTTCAGCCTC
GGCCAGATTCTTTATTTCTCCGAGAGCAAGGTATCCCTGACCGAAGGGATTGCCGAAGAACGCCCCAGCTCATCGGCCAT
TGCAGCCGAACTGGATGCCCATCTCTACGAAGACTGGTATTTCAGTGGCGCGCTGCAATACGATGCCCGCACCCGGGATA
ATAAAAAATCAGAGTTCACACTGGATTACCGTCCCGGCGGTGAAAAGCTGGTGCAGTTCAGCTACCGCTATGTGCCGGAT
TTGGTGAATACCAACACCAATGAAGAGGTTGGCATCAGCCAGGCCGGTATGCGCACCACCTGGCCCTTGACCGATAGCCT
CTACTTTGTCGGCAACTGGTACTACGACCTCAATGAAAGTCGTTCGGTAGAAGCCTATACAGGTTTCCAGTATGAAAGCT
GCTGCTGGGCCGTGCGTTTGAGCTACCACTACCGGATAAAGACCAATTACGATGACGATTTCAATCCGGTGCAGGATAAC
CGCGAACTCTTTGAAAGCGGTGTGTACCTGAATTTCGTGATAAAAGGCCTTGGCGGCTCAGGCCCCATGGGTGTCAGCGA
CATGCTGGATGAAGGGCTGTTCAACTACAGAAAGCCGCTTTATCTGAGGAATTAA

Upstream 100 bases:

>100_bases
TTGTACTGGAGACGAGTGCAACTTTTCCCTCCTCTCAGTTTCCAGTTAAAGCCCGGATAGTGAAATCCAGATAACGAATA
TCAAACTGAATACTCTTAAG

Downstream 100 bases:

>100_bases
CACAGAAATGTGGTAGATTGCGAAACCACATTCAGGACGCGTTGTCCAAACAGGTTAACACTGCCGGGTTTTCTGTGCCG
GTGAGGTGGAAGAAAACCGA

Product: organic solvent tolerance protein

Products: NA

Alternate protein names: Organic solvent tolerance protein [H]

Number of amino acids: Translated: 764; Mature: 764

Protein sequence:

>764_residues
MQIRYILALGLLPCQAMANDAVPEPAPDQCLVAPPIPLPSAPQSASAEEQVEIRSVSSDAVMNQNATFEGDVQFRQGNRS
ISADRANMDYEKQQLNAEGNLVFQDSQFTVTADNLSAKIKDNSATLNGAQYWLHGQQVHGNARKLEITKDNNLILSGTDF
TTCPPGDSSWLLEAERIKIDSSEEWGEIWNAKMRIADIPVFYVPYMTVPVSDKRKTGFLFPQFSTSTTNGVEIATPWYWN
IAPEYDLTLTPHYMSARGLYLQSEFRYLAGDAQAGRVNLEYLGSDRLLENSDDRYLYHWEHRGAIDKHWRVNAAFTDVSD
NNYFNDLDSEVARATDNQLSRIGEMSYFENDWNISARVQDIKVLGEDEVPYQVMPQLSFNYRSQDLLNTLEFSFFGEATN
FEHKEQDQVTATRLHLQPTLSLPIHGPAGSLTSELTLLQTNYWQRNTDLMPDSELNSSVSRTLPRAKVHGQINLERNTQW
LGESYRQTLEPQVQYLYVGYEDQDDIGIYDSARLQDDYYGLFRARRFSGLDRISDANQLTLGLTTRFFDDRNQEQFKFSL
GQILYFSESKVSLTEGIAEERPSSSAIAAELDAHLYEDWYFSGALQYDARTRDNKKSEFTLDYRPGGEKLVQFSYRYVPD
LVNTNTNEEVGISQAGMRTTWPLTDSLYFVGNWYYDLNESRSVEAYTGFQYESCCWAVRLSYHYRIKTNYDDDFNPVQDN
RELFESGVYLNFVIKGLGGSGPMGVSDMLDEGLFNYRKPLYLRN

Sequences:

>Translated_764_residues
MQIRYILALGLLPCQAMANDAVPEPAPDQCLVAPPIPLPSAPQSASAEEQVEIRSVSSDAVMNQNATFEGDVQFRQGNRS
ISADRANMDYEKQQLNAEGNLVFQDSQFTVTADNLSAKIKDNSATLNGAQYWLHGQQVHGNARKLEITKDNNLILSGTDF
TTCPPGDSSWLLEAERIKIDSSEEWGEIWNAKMRIADIPVFYVPYMTVPVSDKRKTGFLFPQFSTSTTNGVEIATPWYWN
IAPEYDLTLTPHYMSARGLYLQSEFRYLAGDAQAGRVNLEYLGSDRLLENSDDRYLYHWEHRGAIDKHWRVNAAFTDVSD
NNYFNDLDSEVARATDNQLSRIGEMSYFENDWNISARVQDIKVLGEDEVPYQVMPQLSFNYRSQDLLNTLEFSFFGEATN
FEHKEQDQVTATRLHLQPTLSLPIHGPAGSLTSELTLLQTNYWQRNTDLMPDSELNSSVSRTLPRAKVHGQINLERNTQW
LGESYRQTLEPQVQYLYVGYEDQDDIGIYDSARLQDDYYGLFRARRFSGLDRISDANQLTLGLTTRFFDDRNQEQFKFSL
GQILYFSESKVSLTEGIAEERPSSSAIAAELDAHLYEDWYFSGALQYDARTRDNKKSEFTLDYRPGGEKLVQFSYRYVPD
LVNTNTNEEVGISQAGMRTTWPLTDSLYFVGNWYYDLNESRSVEAYTGFQYESCCWAVRLSYHYRIKTNYDDDFNPVQDN
RELFESGVYLNFVIKGLGGSGPMGVSDMLDEGLFNYRKPLYLRN
>Mature_764_residues
MQIRYILALGLLPCQAMANDAVPEPAPDQCLVAPPIPLPSAPQSASAEEQVEIRSVSSDAVMNQNATFEGDVQFRQGNRS
ISADRANMDYEKQQLNAEGNLVFQDSQFTVTADNLSAKIKDNSATLNGAQYWLHGQQVHGNARKLEITKDNNLILSGTDF
TTCPPGDSSWLLEAERIKIDSSEEWGEIWNAKMRIADIPVFYVPYMTVPVSDKRKTGFLFPQFSTSTTNGVEIATPWYWN
IAPEYDLTLTPHYMSARGLYLQSEFRYLAGDAQAGRVNLEYLGSDRLLENSDDRYLYHWEHRGAIDKHWRVNAAFTDVSD
NNYFNDLDSEVARATDNQLSRIGEMSYFENDWNISARVQDIKVLGEDEVPYQVMPQLSFNYRSQDLLNTLEFSFFGEATN
FEHKEQDQVTATRLHLQPTLSLPIHGPAGSLTSELTLLQTNYWQRNTDLMPDSELNSSVSRTLPRAKVHGQINLERNTQW
LGESYRQTLEPQVQYLYVGYEDQDDIGIYDSARLQDDYYGLFRARRFSGLDRISDANQLTLGLTTRFFDDRNQEQFKFSL
GQILYFSESKVSLTEGIAEERPSSSAIAAELDAHLYEDWYFSGALQYDARTRDNKKSEFTLDYRPGGEKLVQFSYRYVPD
LVNTNTNEEVGISQAGMRTTWPLTDSLYFVGNWYYDLNESRSVEAYTGFQYESCCWAVRLSYHYRIKTNYDDDFNPVQDN
RELFESGVYLNFVIKGLGGSGPMGVSDMLDEGLFNYRKPLYLRN

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis [H]

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family [H]

Homologues:

Organism=Escherichia coli, GI1786239, Length=786, Percent_Identity=33.969465648855, Blast_Score=461, Evalue=1e-131,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020889
- InterPro:   IPR005653
- InterPro:   IPR007543 [H]

Pfam domain/function: PF03968 OstA; PF04453 OstA_C [H]

EC number: NA

Molecular weight: Translated: 87369; Mature: 87369

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIRYILALGLLPCQAMANDAVPEPAPDQCLVAPPIPLPSAPQSASAEEQVEIRSVSSDA
CEEEEEEEECCCCHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEECCCCH
VMNQNATFEGDVQFRQGNRSISADRANMDYEKQQLNAEGNLVFQDSQFTVTADNLSAKIK
HCCCCCCEECEEEEECCCCCCCCCCCCCCHHHHHCCCCCCEEEECCEEEEEECCCEEEEE
DNSATLNGAQYWLHGQQVHGNARKLEITKDNNLILSGTDFTTCPPGDSSWLLEAERIKID
CCCCEECCEEEEEECEEECCCCEEEEEECCCCEEEECCCCCCCCCCCCCEEEEEEEEEEC
SSEEWGEIWNAKMRIADIPVFYVPYMTVPVSDKRKTGFLFPQFSTSTTNGVEIATPWYWN
CCHHHHHHCCCEEEEEECCEEEECEEEEECCCCCCCCEEEECCCCCCCCCEEEECCEEEE
IAPEYDLTLTPHYMSARGLYLQSEFRYLAGDAQAGRVNLEYLGSDRLLENSDDRYLYHWE
CCCCCCEEECCCHHCCCCEEEECCCCEEECCCCCCEEEEEEECCCCCCCCCCCCEEEEEE
HRGAIDKHWRVNAAFTDVSDNNYFNDLDSEVARATDNQLSRIGEMSYFENDWNISARVQD
CCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEE
IKVLGEDEVPYQVMPQLSFNYRSQDLLNTLEFSFFGEATNFEHKEQDQVTATRLHLQPTL
EEEECCCCCCCEEECCCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCEEEEEEEEEEEE
SLPIHGPAGSLTSELTLLQTNYWQRNTDLMPDSELNSSVSRTLPRAKVHGQINLERNTQW
EEEECCCCCCCHHCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEECEEEEECCCCHH
LGESYRQTLEPQVQYLYVGYEDQDDIGIYDSARLQDDYYGLFRARRFSGLDRISDANQLT
HHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHCCCCCEEE
LGLTTRFFDDRNQEQFKFSLGQILYFSESKVSLTEGIAEERPSSSAIAAELDAHLYEDWY
EEEEEEECCCCCHHHHHEEECEEEEEECCCEEHHHHHHHCCCCCCCCHHHHHHHHHHCEE
FSGALQYDARTRDNKKSEFTLDYRPGGEKLVQFSYRYVPDLVNTNTNEEVGISQAGMRTT
ECCEEEECCCCCCCCCCEEEEEECCCCHHHHEEHHHHCCHHHCCCCCCCCCCCCCCCEEE
WPLTDSLYFVGNWYYDLNESRSVEAYTGFQYESCCWAVRLSYHYRIKTNYDDDFNPVQDN
CCCCCCEEEEEEEEEECCCCCCEEEEECCCHHCEEEEEEEEEEEEEECCCCCCCCCCCCC
RELFESGVYLNFVIKGLGGSGPMGVSDMLDEGLFNYRKPLYLRN
HHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEECC
>Mature Secondary Structure
MQIRYILALGLLPCQAMANDAVPEPAPDQCLVAPPIPLPSAPQSASAEEQVEIRSVSSDA
CEEEEEEEECCCCHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEECCCCH
VMNQNATFEGDVQFRQGNRSISADRANMDYEKQQLNAEGNLVFQDSQFTVTADNLSAKIK
HCCCCCCEECEEEEECCCCCCCCCCCCCCHHHHHCCCCCCEEEECCEEEEEECCCEEEEE
DNSATLNGAQYWLHGQQVHGNARKLEITKDNNLILSGTDFTTCPPGDSSWLLEAERIKID
CCCCEECCEEEEEECEEECCCCEEEEEECCCCEEEECCCCCCCCCCCCCEEEEEEEEEEC
SSEEWGEIWNAKMRIADIPVFYVPYMTVPVSDKRKTGFLFPQFSTSTTNGVEIATPWYWN
CCHHHHHHCCCEEEEEECCEEEECEEEEECCCCCCCCEEEECCCCCCCCCEEEECCEEEE
IAPEYDLTLTPHYMSARGLYLQSEFRYLAGDAQAGRVNLEYLGSDRLLENSDDRYLYHWE
CCCCCCEEECCCHHCCCCEEEECCCCEEECCCCCCEEEEEEECCCCCCCCCCCCEEEEEE
HRGAIDKHWRVNAAFTDVSDNNYFNDLDSEVARATDNQLSRIGEMSYFENDWNISARVQD
CCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEE
IKVLGEDEVPYQVMPQLSFNYRSQDLLNTLEFSFFGEATNFEHKEQDQVTATRLHLQPTL
EEEECCCCCCCEEECCCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCEEEEEEEEEEEE
SLPIHGPAGSLTSELTLLQTNYWQRNTDLMPDSELNSSVSRTLPRAKVHGQINLERNTQW
EEEECCCCCCCHHCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEECEEEEECCCCHH
LGESYRQTLEPQVQYLYVGYEDQDDIGIYDSARLQDDYYGLFRARRFSGLDRISDANQLT
HHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHCCCCCEEE
LGLTTRFFDDRNQEQFKFSLGQILYFSESKVSLTEGIAEERPSSSAIAAELDAHLYEDWY
EEEEEEECCCCCHHHHHEEECEEEEEECCCEEHHHHHHHCCCCCCCCHHHHHHHHHHCEE
FSGALQYDARTRDNKKSEFTLDYRPGGEKLVQFSYRYVPDLVNTNTNEEVGISQAGMRTT
ECCEEEECCCCCCCCCCEEEEEECCCCHHHHEEHHHHCCHHHCCCCCCCCCCCCCCCEEE
WPLTDSLYFVGNWYYDLNESRSVEAYTGFQYESCCWAVRLSYHYRIKTNYDDDFNPVQDN
CCCCCCEEEEEEEEEECCCCCCEEEEECCCHHCEEEEEEEEEEEEEECCCCCCCCCCCCC
RELFESGVYLNFVIKGLGGSGPMGVSDMLDEGLFNYRKPLYLRN
HHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA