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The map label for this gene is tas [H]

Identifier: 119775908

GI number: 119775908

Start: 3318543

End: 3319580

Strand: Direct

Name: tas [H]

Synonym: Sama_2776

Alternate gene names: 119775908

Gene position: 3318543-3319580 (Clockwise)

Preceding gene: 119775907

Following gene: 119775909

Centisome position: 77.07

GC content: 57.03

Gene sequence:

>1038_bases
ATGGAATACCGCCGCCTGCCCCACTCCAATCTGGAGGTCAGTTCCCTGTGCCTTGGCACCATGACCTGGGGCGAACAAAA
TACCCAGGCCGACGCCTTTGCACAGCTGGACTACGCCATTGGCCGGGGTATCAACTTTATCGACGCCGCCGAAATGTATC
CTGTGCCGCCCCGCCCCGAGACCCAGGGGGCGACAGAAGAGATCCTCGGCAACTACCTTAAGGCCCGTGGCAATCGCGAT
GAACTGGTGATCGCCACCAAGATTTGTGCCCACGGAGGCAAGGGCGACTATATCCGCCCCAAGATGGCACTGGACTGGAA
CAACATCCACGAAGCCGTGGATCAATCTCTAACCCGTCTGGGCATAGACACCATCGACCTGTATCAGCTGCACTGGCCCG
ACAGAAACACCAATTTCTTCGGCGAGCTGATGTACAAGCGTGACGATGCCGAGCACCAAACCCCCATTATCGAAACCCTC
GAGGCCCTGGCCGAGCTCATTCGGGTGGGGAAAATCCGTTATATCGGTGTCTCCAACGAAACCCCCTGGGGCATCATGAA
GTACCTGCATCTGGCCGAAAAACATGGTCTGCCCCGCATCGTTTCGATTCAAAACCCCTACAACCTGCTTAACCGCAGTT
TTGAAGTGGGCATGAGCGAAATCAGTCACAGGGAAGAGTTGCCGCTGCTGGCCTACTCGCCACTGGCCTTTGGCACCTTA
AGCGGAAAATACCTCAACGGCGAATGGCCGGAGCAGGCACGCCTGACCCTGTTCAAGCGTTTTGCCCGCTACAGCAGCGA
CCATGCCAAAGCAGCCACCGAGGCCTATGTGAATCTGGCGCGGGAGTTCAATTTAAGTCCGGCGCAAATGGCGCTGGCCT
TTGTAAACAGCCGCAGCTTTGTGGGCAGCAATATCATAGGCGCCACCTCGGTGGAGCAGCTGAAAGAGAACATCGACAGC
CTCGATGTCAGCCTGCCCGAGGCGCTTTTTGAGCGCATCAATGCCCTCGGGGAAATCTACCGTTTACCCTGCCCTTAA

Upstream 100 bases:

>100_bases
TTTTGTGCAAGCGATAAGGCAAGGCCCTGTGCTGCCTTGCTTTATCAGCCAGACTTGATAGCTTCAAACTCATAACGCCT
ATTATGCTGAGGATGTTTTG

Downstream 100 bases:

>100_bases
GTTACGGGCTGCCAATACTCATCAAATATTGCGTCAATTCCTGTTTCAATCCCGGCGCGGCCTTGCAATGGCCGCGCAAA
TCCTTAAAGATCGACTCAAT

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MEYRRLPHSNLEVSSLCLGTMTWGEQNTQADAFAQLDYAIGRGINFIDAAEMYPVPPRPETQGATEEILGNYLKARGNRD
ELVIATKICAHGGKGDYIRPKMALDWNNIHEAVDQSLTRLGIDTIDLYQLHWPDRNTNFFGELMYKRDDAEHQTPIIETL
EALAELIRVGKIRYIGVSNETPWGIMKYLHLAEKHGLPRIVSIQNPYNLLNRSFEVGMSEISHREELPLLAYSPLAFGTL
SGKYLNGEWPEQARLTLFKRFARYSSDHAKAATEAYVNLAREFNLSPAQMALAFVNSRSFVGSNIIGATSVEQLKENIDS
LDVSLPEALFERINALGEIYRLPCP

Sequences:

>Translated_345_residues
MEYRRLPHSNLEVSSLCLGTMTWGEQNTQADAFAQLDYAIGRGINFIDAAEMYPVPPRPETQGATEEILGNYLKARGNRD
ELVIATKICAHGGKGDYIRPKMALDWNNIHEAVDQSLTRLGIDTIDLYQLHWPDRNTNFFGELMYKRDDAEHQTPIIETL
EALAELIRVGKIRYIGVSNETPWGIMKYLHLAEKHGLPRIVSIQNPYNLLNRSFEVGMSEISHREELPLLAYSPLAFGTL
SGKYLNGEWPEQARLTLFKRFARYSSDHAKAATEAYVNLAREFNLSPAQMALAFVNSRSFVGSNIIGATSVEQLKENIDS
LDVSLPEALFERINALGEIYRLPCP
>Mature_345_residues
MEYRRLPHSNLEVSSLCLGTMTWGEQNTQADAFAQLDYAIGRGINFIDAAEMYPVPPRPETQGATEEILGNYLKARGNRD
ELVIATKICAHGGKGDYIRPKMALDWNNIHEAVDQSLTRLGIDTIDLYQLHWPDRNTNFFGELMYKRDDAEHQTPIIETL
EALAELIRVGKIRYIGVSNETPWGIMKYLHLAEKHGLPRIVSIQNPYNLLNRSFEVGMSEISHREELPLLAYSPLAFGTL
SGKYLNGEWPEQARLTLFKRFARYSSDHAKAATEAYVNLAREFNLSPAQMALAFVNSRSFVGSNIIGATSVEQLKENIDS
LDVSLPEALFERINALGEIYRLPCP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436962, Length=350, Percent_Identity=30.2857142857143, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI27436964, Length=351, Percent_Identity=31.0541310541311, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI27436969, Length=346, Percent_Identity=30.3468208092486, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4504825, Length=344, Percent_Identity=30.2325581395349, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI27436966, Length=351, Percent_Identity=30.7692307692308, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI27436971, Length=352, Percent_Identity=28.9772727272727, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI223718702, Length=347, Percent_Identity=25.0720461095101, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI41327764, Length=347, Percent_Identity=25.9365994236311, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI41152114, Length=355, Percent_Identity=26.1971830985915, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789199, Length=346, Percent_Identity=58.6705202312139, Blast_Score=417, Evalue=1e-118,
Organism=Escherichia coli, GI87081735, Length=343, Percent_Identity=32.9446064139942, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1789375, Length=341, Percent_Identity=31.0850439882698, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788070, Length=293, Percent_Identity=30.3754266211604, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788081, Length=324, Percent_Identity=29.0123456790123, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787674, Length=323, Percent_Identity=24.7678018575851, Blast_Score=69, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319958, Length=305, Percent_Identity=27.2131147540984, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323998, Length=348, Percent_Identity=27.0114942528736, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6325169, Length=363, Percent_Identity=25.068870523416, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319951, Length=327, Percent_Identity=25.6880733944954, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6322615, Length=265, Percent_Identity=26.4150943396226, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24646159, Length=222, Percent_Identity=29.2792792792793, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38934; Mature: 38934

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRRLPHSNLEVSSLCLGTMTWGEQNTQADAFAQLDYAIGRGINFIDAAEMYPVPPRPE
CCCCCCCCCCCCHHHHHEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCC
TQGATEEILGNYLKARGNRDELVIATKICAHGGKGDYIRPKMALDWNNIHEAVDQSLTRL
CCCCHHHHHHHHHHCCCCCCCEEEEEHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHH
GIDTIDLYQLHWPDRNTNFFGELMYKRDDAEHQTPIIETLEALAELIRVGKIRYIGVSNE
CCCEEEEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCC
TPWGIMKYLHLAEKHGLPRIVSIQNPYNLLNRSFEVGMSEISHREELPLLAYSPLAFGTL
CCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHCCC
SGKYLNGEWPEQARLTLFKRFARYSSDHAKAATEAYVNLAREFNLSPAQMALAFVNSRSF
CCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
VGSNIIGATSVEQLKENIDSLDVSLPEALFERINALGEIYRLPCP
CCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEYRRLPHSNLEVSSLCLGTMTWGEQNTQADAFAQLDYAIGRGINFIDAAEMYPVPPRPE
CCCCCCCCCCCCHHHHHEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCC
TQGATEEILGNYLKARGNRDELVIATKICAHGGKGDYIRPKMALDWNNIHEAVDQSLTRL
CCCCHHHHHHHHHHCCCCCCCEEEEEHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHH
GIDTIDLYQLHWPDRNTNFFGELMYKRDDAEHQTPIIETLEALAELIRVGKIRYIGVSNE
CCCEEEEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCC
TPWGIMKYLHLAEKHGLPRIVSIQNPYNLLNRSFEVGMSEISHREELPLLAYSPLAFGTL
CCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHCCC
SGKYLNGEWPEQARLTLFKRFARYSSDHAKAATEAYVNLAREFNLSPAQMALAFVNSRSF
CCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
VGSNIIGATSVEQLKENIDSLDVSLPEALFERINALGEIYRLPCP
CCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]