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The map label for this gene is crp [C]

Identifier: 119775817

GI number: 119775817

Start: 3214288

End: 3215106

Strand: Direct

Name: crp [C]

Synonym: Sama_2685

Alternate gene names: 119775817

Gene position: 3214288-3215106 (Clockwise)

Preceding gene: 119775816

Following gene: 119775819

Centisome position: 74.64

GC content: 53.6

Gene sequence:

>819_bases
ATGATCACCGACATTCAGACCAGTCAGATTATTCATCAGCATCATCTTTTTTCGCCCCTCGAGCCGAGGCAATTGGAACA
GTTGCTGGCGGGAGCCGGTCGCATCAGCTTGTCTGCGCAGGAACACCTGTTTCATCGTCAGGACCCCGCCAAACGCTTTT
ATCTGGTGCTCAAGGGCAACCTGCAACTCTATATCACCAGCGCCCAGGGGCAGCTTAAGGTGCTGGAGGTCGTGCGGCCA
AATCACTCTTTCGCCGAAGCGCTGATTTTCAATCAGGAACCCTTTTACCCTGTGTCTGCCCAGGCGGTACAAGCCTGCGA
GCTCATCAGCTTTGATGCCGAGGCCTATCTGGCCATTCTCAAGCAAAGTCCGGATGCCTGCATTGCAGTCATGGCGGCCA
TGAGTATGCGCCTGCACAAGGATATTCAGGAGATTGAAAACCTGTCGCTGCAAAATGCCGAGAACCGGCTGCTGATGTTT
TTGCTCAGGCACAGCAAACCTTCCGGGGATAACAGCGGCATGCTGACCCTGGATGTGCCCAAACGAACCCTGGCATCGCG
GTTGTCAATTCAGCCGGAGACCTTCTCCCGACTGATAAAAAAGATGAACAGTGAAGGTATGATAGAAGAGTCGCGGGGAC
TGATTAACATCCCGGATCTCAGCCGTCTTTATGAAAGTATTCAGCAGCTTGAACCAGCGGCATGCGGGCGCTGCCCCATG
GCCATGAAAAAGGCAGCACTGAAACAGGCACAAGCAGCAAGCAAAGTCAGTTTGAATACCCGAGCACTGGCGGACAGAAT
TCCCGCCAGCGTGAGTTAA

Upstream 100 bases:

>100_bases
ATCATTGATCTCAGGCTTATCCATCAAAGGCGATCCAGATCAATGATTTGAATGGAAATGTGACTTAGTCTGCCCTTCAG
TAACCGAGCCGGGGGGCAGC

Downstream 100 bases:

>100_bases
TCCAAAGCCGTCAGACAGCGTCTTGCAGTCTCCTGCTTGAAGCTGTCAGGTCCCGGCAGTCGTCTCGCAGCTGCCAATCA
GGGTCTTGAAGTGTTGCCCC

Product: cAMP-binding protein

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Regulator Of Biofilm Formation Fnr Family; Regulatory Protein; CAMP-Dependent Transcriptional Regulator; Transcription Regulator Protein Crp/Fnr Family; Transcription Regulator; Transcriptional Activator FtrB; Transcriptional Regulator Dnr; Cyclic AMP Receptor Protein; Transcriptional Regulator DnrS; Nitrite And Nitric Oxide Reductase Regulator; Transcriptional Regulator Dnr Type; DnrE Protein; Fnr-Like Transcriptional Activator; DNR Protein; Transcription Regulator Protein; Transcriptional Regulator Dnr-Type; Fnr-Like Regulatory Protein; Catabolite Gene Activator; Denitrification Transcriptional Regulator Protein; FNR-Like Transcriptional Regulator; CAMP-Bindin Transcriptional Regulator; Transcriptional Regulator Dnr/Nnr Type

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MITDIQTSQIIHQHHLFSPLEPRQLEQLLAGAGRISLSAQEHLFHRQDPAKRFYLVLKGNLQLYITSAQGQLKVLEVVRP
NHSFAEALIFNQEPFYPVSAQAVQACELISFDAEAYLAILKQSPDACIAVMAAMSMRLHKDIQEIENLSLQNAENRLLMF
LLRHSKPSGDNSGMLTLDVPKRTLASRLSIQPETFSRLIKKMNSEGMIEESRGLINIPDLSRLYESIQQLEPAACGRCPM
AMKKAALKQAQAASKVSLNTRALADRIPASVS

Sequences:

>Translated_272_residues
MITDIQTSQIIHQHHLFSPLEPRQLEQLLAGAGRISLSAQEHLFHRQDPAKRFYLVLKGNLQLYITSAQGQLKVLEVVRP
NHSFAEALIFNQEPFYPVSAQAVQACELISFDAEAYLAILKQSPDACIAVMAAMSMRLHKDIQEIENLSLQNAENRLLMF
LLRHSKPSGDNSGMLTLDVPKRTLASRLSIQPETFSRLIKKMNSEGMIEESRGLINIPDLSRLYESIQQLEPAACGRCPM
AMKKAALKQAQAASKVSLNTRALADRIPASVS
>Mature_272_residues
MITDIQTSQIIHQHHLFSPLEPRQLEQLLAGAGRISLSAQEHLFHRQDPAKRFYLVLKGNLQLYITSAQGQLKVLEVVRP
NHSFAEALIFNQEPFYPVSAQAVQACELISFDAEAYLAILKQSPDACIAVMAAMSMRLHKDIQEIENLSLQNAENRLLMF
LLRHSKPSGDNSGMLTLDVPKRTLASRLSIQPETFSRLIKKMNSEGMIEESRGLINIPDLSRLYESIQQLEPAACGRCPM
AMKKAALKQAQAASKVSLNTRALADRIPASVS

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 30314; Mature: 30314

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITDIQTSQIIHQHHLFSPLEPRQLEQLLAGAGRISLSAQEHLFHRQDPAKRFYLVLKGN
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEECHHHHHHHCCCCHHEEEEEEECC
LQLYITSAQGQLKVLEVVRPNHSFAEALIFNQEPFYPVSAQAVQACELISFDAEAYLAIL
EEEEEECCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHH
KQSPDACIAVMAAMSMRLHKDIQEIENLSLQNAENRLLMFLLRHSKPSGDNSGMLTLDVP
HCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECC
KRTLASRLSIQPETFSRLIKKMNSEGMIEESRGLINIPDLSRLYESIQQLEPAACGRCPM
HHHHHHHHCCCHHHHHHHHHHHCCCCCCHHCCCEEECCCHHHHHHHHHHHCHHHCCCCHH
AMKKAALKQAQAASKVSLNTRALADRIPASVS
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MITDIQTSQIIHQHHLFSPLEPRQLEQLLAGAGRISLSAQEHLFHRQDPAKRFYLVLKGN
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEECHHHHHHHCCCCHHEEEEEEECC
LQLYITSAQGQLKVLEVVRPNHSFAEALIFNQEPFYPVSAQAVQACELISFDAEAYLAIL
EEEEEECCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHH
KQSPDACIAVMAAMSMRLHKDIQEIENLSLQNAENRLLMFLLRHSKPSGDNSGMLTLDVP
HCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECC
KRTLASRLSIQPETFSRLIKKMNSEGMIEESRGLINIPDLSRLYESIQQLEPAACGRCPM
HHHHHHHHCCCHHHHHHHHHHHCCCCCCHHCCCEEECCCHHHHHHHHHHHCHHHCCCCHH
AMKKAALKQAQAASKVSLNTRALADRIPASVS
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA