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The map label for this gene is hlyB [H]

Identifier: 119775741

GI number: 119775741

Start: 3124600

End: 3126465

Strand: Reverse

Name: hlyB [H]

Synonym: Sama_2609

Alternate gene names: 119775741

Gene position: 3126465-3124600 (Counterclockwise)

Preceding gene: 119775746

Following gene: 119775740

Centisome position: 72.6

GC content: 52.3

Gene sequence:

>1866_bases
ATGCTCATTCGTCAAAAATTAATGCTGAGCGCAGCGTTGTCGATAGGTGCCCTGGTGGCGATGTTCGGTTTGCAGCTGTA
TTCCGGCAAAACTCAGGTTGAGTTGGCGTTGGCCGCTCAAACCGTGGTTGAACTGGAAAGGGACATGCTCGAGCTTCGCA
AGGATGAGAAAGACTTTTTAACCCGCAGTGATATGGCCTATGTTCAGGGGCATGCCCAACATGCTGCAGAGCTCAAAACC
AAACTGAGCACTGTCAAGCAAGTATTTGAAAAATATGACATGCCCATGGCGCCTTTGGATCGGTTTGAGAGTTTGTTAGG
CCAATACCTGACACTGTTTTCCGACGTGGTCACACTACAGCAGCAAATTGGTTTGACCCCCAAGTCCGGCTTGTATGGCC
AGCTCAGAGAGGCGGTACACAATGTGGAAACCCTACTGAAAGAACACAATAAGCCAGAGCTGGCAGTACAGATGCTACAA
CTGCGTCGCAACGAAAAAGATTTTATGTTACGCCGTGATGCCGGTTATCTGGATAAGTTTCAGCAAACTCTGCGCAGCTT
TGACAGCACCCTTGATGGGTCCGATTTGAGTCCTGACGTCGCGGATGAAATCCGTCGCCTCATGAAGGATTATCAAATGA
ATTTCGAGGCCTTGGTTAATAAAGAGAAGGAATTTGGTCTGGGCAAAGAGGACGGCAAAATGGGCGCGCTCAGGTCTGTC
ATCGACCAGTCTGAGCAGGCGACACAGGAGCTGCGGGAGCTTGCGCTTCATGAAATTCATGATGAAGAGGGTGACAGTGT
TGCCATGGCGACAACCCTGTTTGCCGTGATTGCTGTGCTGGTTGCTATTGTGACCTTTATGATCATCCGCGCCATCATTA
CCCCCATCAACAATATCAATCAGGTGATTTCACATGTTGGCAAGGATAAAAACCTGACCCTGCGTTGCGATACACAAGGG
GGTGACGAAATCGCTGAAATAGGCCAGCACTTTAACGAAATGGTTGAAAGTTTCCGTGCGCTTATCCAGCAAGTAAACGA
TGCTGTGAACGTCATGAATGAATCCTGTCAGGAGCTGTCAGCCAATGCGACCCAGGCGTCCGACGGGGTACTTAGGCAGC
TGAATGAAACCGACATGGTAGCTACCGCCATTACTGAGATGGGGGCCACCATCGATGAGATTGCCAAAAACACCGAACTG
GCGGCCGAGCGTGCCAACCATACACACACCAACGCTCAGGTAGGACAGCAGAGCGTTGAGCAAACCATCGAAAAAATCCA
GTCACTGGCGCAGCAGCTTAACAATTCGGCCTCTGTGGTGGCTGAGCTTGAGCGTGACAGCGGCACCATAGGCAGTGTGC
TGGATGTGATCCGGGGTATTGCTGAGCAAACCAATCTACTGGCCCTGAACGCTGCCATTGAAGCCGCCCGTGCCGGTGAG
CAGGGGAGGGGCTTTGCCGTGGTGGCCGATGAGGTCCGCTCGCTGGCGATGCGAACACAGGAGTCGACCGAAGAAATCGC
CGGTATTATCCAAACTCTGCAAAGCCGCACCCGCTCCATTGTGCAGCTGATGGAAGCCAGTCAGCGCCAGGGCGGAGAAA
GCGCTGAGCAAGCTGCCAGTGCCGGTACCATGTTGGCGCAGATAAATCAGGATGTGACCAACATTATGGACATGAGTACC
CAGATAGCCGCGGCCATCGAAGAGCAAAGCTCTGTGGCGGCAGAAGTGAATAAAAATGTGGTGGTTATCAGGGATATCGC
CGAAGAATCTTCCCATGCGGCTATGGCGAACGCTAAAGCCTCCGACGATGTGCGGGAACGGGCTGAGTATTTGCAGAGGG
CAGTTAGCCAGTTCCGCGTGAGTTGA

Upstream 100 bases:

>100_bases
CAATCGACGTGTGACAGTTTTGTGACCACCAAGGCCTTAGTTCCCAAATAGATGCCTGGGGGTCTACAGTTATTAAAGAT
CGCTACATGGGGAAAGTAAC

Downstream 100 bases:

>100_bases
GTCAGAGTGTCGTGAGAAAGCCGCCGAAAGGCGGCTTTTTTTCGGACAAATGCCAGGTGCGGGGCTAAGCTTAAATGAAG
CTTCATCCGGGGATATTTGT

Product: putative methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MLIRQKLMLSAALSIGALVAMFGLQLYSGKTQVELALAAQTVVELERDMLELRKDEKDFLTRSDMAYVQGHAQHAAELKT
KLSTVKQVFEKYDMPMAPLDRFESLLGQYLTLFSDVVTLQQQIGLTPKSGLYGQLREAVHNVETLLKEHNKPELAVQMLQ
LRRNEKDFMLRRDAGYLDKFQQTLRSFDSTLDGSDLSPDVADEIRRLMKDYQMNFEALVNKEKEFGLGKEDGKMGALRSV
IDQSEQATQELRELALHEIHDEEGDSVAMATTLFAVIAVLVAIVTFMIIRAIITPINNINQVISHVGKDKNLTLRCDTQG
GDEIAEIGQHFNEMVESFRALIQQVNDAVNVMNESCQELSANATQASDGVLRQLNETDMVATAITEMGATIDEIAKNTEL
AAERANHTHTNAQVGQQSVEQTIEKIQSLAQQLNNSASVVAELERDSGTIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
QGRGFAVVADEVRSLAMRTQESTEEIAGIIQTLQSRTRSIVQLMEASQRQGGESAEQAASAGTMLAQINQDVTNIMDMST
QIAAAIEEQSSVAAEVNKNVVVIRDIAEESSHAAMANAKASDDVRERAEYLQRAVSQFRVS

Sequences:

>Translated_621_residues
MLIRQKLMLSAALSIGALVAMFGLQLYSGKTQVELALAAQTVVELERDMLELRKDEKDFLTRSDMAYVQGHAQHAAELKT
KLSTVKQVFEKYDMPMAPLDRFESLLGQYLTLFSDVVTLQQQIGLTPKSGLYGQLREAVHNVETLLKEHNKPELAVQMLQ
LRRNEKDFMLRRDAGYLDKFQQTLRSFDSTLDGSDLSPDVADEIRRLMKDYQMNFEALVNKEKEFGLGKEDGKMGALRSV
IDQSEQATQELRELALHEIHDEEGDSVAMATTLFAVIAVLVAIVTFMIIRAIITPINNINQVISHVGKDKNLTLRCDTQG
GDEIAEIGQHFNEMVESFRALIQQVNDAVNVMNESCQELSANATQASDGVLRQLNETDMVATAITEMGATIDEIAKNTEL
AAERANHTHTNAQVGQQSVEQTIEKIQSLAQQLNNSASVVAELERDSGTIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
QGRGFAVVADEVRSLAMRTQESTEEIAGIIQTLQSRTRSIVQLMEASQRQGGESAEQAASAGTMLAQINQDVTNIMDMST
QIAAAIEEQSSVAAEVNKNVVVIRDIAEESSHAAMANAKASDDVRERAEYLQRAVSQFRVS
>Mature_621_residues
MLIRQKLMLSAALSIGALVAMFGLQLYSGKTQVELALAAQTVVELERDMLELRKDEKDFLTRSDMAYVQGHAQHAAELKT
KLSTVKQVFEKYDMPMAPLDRFESLLGQYLTLFSDVVTLQQQIGLTPKSGLYGQLREAVHNVETLLKEHNKPELAVQMLQ
LRRNEKDFMLRRDAGYLDKFQQTLRSFDSTLDGSDLSPDVADEIRRLMKDYQMNFEALVNKEKEFGLGKEDGKMGALRSV
IDQSEQATQELRELALHEIHDEEGDSVAMATTLFAVIAVLVAIVTFMIIRAIITPINNINQVISHVGKDKNLTLRCDTQG
GDEIAEIGQHFNEMVESFRALIQQVNDAVNVMNESCQELSANATQASDGVLRQLNETDMVATAITEMGATIDEIAKNTEL
AAERANHTHTNAQVGQQSVEQTIEKIQSLAQQLNNSASVVAELERDSGTIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
QGRGFAVVADEVRSLAMRTQESTEEIAGIIQTLQSRTRSIVQLMEASQRQGGESAEQAASAGTMLAQINQDVTNIMDMST
QIAAAIEEQSSVAAEVNKNVVVIRDIAEESSHAAMANAKASDDVRERAEYLQRAVSQFRVS

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=416, Percent_Identity=27.8846153846154, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788195, Length=289, Percent_Identity=31.8339100346021, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI2367378, Length=390, Percent_Identity=28.974358974359, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788194, Length=347, Percent_Identity=29.3948126801153, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1789453, Length=364, Percent_Identity=25.2747252747253, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68344; Mature: 68344

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIRQKLMLSAALSIGALVAMFGLQLYSGKTQVELALAAQTVVELERDMLELRKDEKDFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
TRSDMAYVQGHAQHAAELKTKLSTVKQVFEKYDMPMAPLDRFESLLGQYLTLFSDVVTLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QQIGLTPKSGLYGQLREAVHNVETLLKEHNKPELAVQMLQLRRNEKDFMLRRDAGYLDKF
HHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHCCCCCHHHHH
QQTLRSFDSTLDGSDLSPDVADEIRRLMKDYQMNFEALVNKEKEFGLGKEDGKMGALRSV
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCHHHCCCCCCCCHHHHHHHH
IDQSEQATQELRELALHEIHDEEGDSVAMATTLFAVIAVLVAIVTFMIIRAIITPINNIN
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
QVISHVGKDKNLTLRCDTQGGDEIAEIGQHFNEMVESFRALIQQVNDAVNVMNESCQELS
HHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANATQASDGVLRQLNETDMVATAITEMGATIDEIAKNTELAAERANHTHTNAQVGQQSVE
CCCCHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
QTIEKIQSLAQQLNNSASVVAELERDSGTIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGRGFAVVADEVRSLAMRTQESTEEIAGIIQTLQSRTRSIVQLMEASQRQGGESAEQAAS
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AGTMLAQINQDVTNIMDMSTQIAAAIEEQSSVAAEVNKNVVVIRDIAEESSHAAMANAKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHCCHHHHHHCCCC
SDDVRERAEYLQRAVSQFRVS
CHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLIRQKLMLSAALSIGALVAMFGLQLYSGKTQVELALAAQTVVELERDMLELRKDEKDFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
TRSDMAYVQGHAQHAAELKTKLSTVKQVFEKYDMPMAPLDRFESLLGQYLTLFSDVVTLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QQIGLTPKSGLYGQLREAVHNVETLLKEHNKPELAVQMLQLRRNEKDFMLRRDAGYLDKF
HHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHCCCCCHHHHH
QQTLRSFDSTLDGSDLSPDVADEIRRLMKDYQMNFEALVNKEKEFGLGKEDGKMGALRSV
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCHHHCCCCCCCCHHHHHHHH
IDQSEQATQELRELALHEIHDEEGDSVAMATTLFAVIAVLVAIVTFMIIRAIITPINNIN
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
QVISHVGKDKNLTLRCDTQGGDEIAEIGQHFNEMVESFRALIQQVNDAVNVMNESCQELS
HHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANATQASDGVLRQLNETDMVATAITEMGATIDEIAKNTELAAERANHTHTNAQVGQQSVE
CCCCHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
QTIEKIQSLAQQLNNSASVVAELERDSGTIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGRGFAVVADEVRSLAMRTQESTEEIAGIIQTLQSRTRSIVQLMEASQRQGGESAEQAAS
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AGTMLAQINQDVTNIMDMSTQIAAAIEEQSSVAAEVNKNVVVIRDIAEESSHAAMANAKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHCCHHHHHHCCCC
SDDVRERAEYLQRAVSQFRVS
CHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]