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The map label for this gene is mrdB [H]

Identifier: 119775721

GI number: 119775721

Start: 3097233

End: 3098339

Strand: Direct

Name: mrdB [H]

Synonym: Sama_2589

Alternate gene names: 119775721

Gene position: 3097233-3098339 (Clockwise)

Preceding gene: 119775720

Following gene: 119775722

Centisome position: 71.93

GC content: 55.19

Gene sequence:

>1107_bases
ATGACAAGGGATCATGCCCGTAAGAATATCTGGCAACGGATGCACATCGACTTACCGCTTTTGCTCGGACTGCTGGCCAT
CATGGGGTTTGGGCTGTTTGTTATTTGGTCCGCCTCGGGTGAAGATCCAGCCATGCTGGAGCGGCAACTGGTACGCATGG
GGCTCTCCCTCGGCATCATGCTGTTTATGGCACAGATAAATCCGGAAATTCTGCGCCGCTGGGCCCTGCCGATTTATATC
GCCGGGATTATCCTGCTGCTTGGGGTGCACTTTTTCGGGGAAATCAATAAAGGCGCCCAGCGCTGGCTGAATCTGGGCTT
TATGGAGTTTCAGCCCTCAGAGCTTATCAAGCTCGCCTTCCCCATCACCATGGCCTGGTTTATCAGCAAGTTTACCCTGC
CACCCAAGAAACGGTATCTGGCGGCTGCGGCAGTTATCATGCTTATTCCAACCCTGTTGATTGCCAAGCAACCCGACCTG
GGGACTTCCATCCTGGTGGCGGCCTCCGGCATCTTTGTACTCTTCCTGTCCGGGATGAGCTGGTACATAGTACTTGGGCT
GCTGGCTTCGGTGCTGTCGTTTCTGCCGATACTCTGGTATTTCCTGATGCACGACTACCAGCGCCGCCGGGTGTTGACAC
TGCTTGATCCGGAAAAAGATCCGCTTGGCGCCGGTTATCACATTATCCAGTCGAAAATCGCCATCGGCTCCGGTGGCGTG
GACGGCAAAGGCTGGCTCCACGGCACCCAGTCGCAGCTGGAGTTTCTGCCCGAACGTCACACCGACTTTATCTTCGCTGT
GATTGGCGAGGAGTTCGGTCTCATTGGCGCCATTGTGTTGCTGGCCATGTACATCTACGTGATTGGTCGGGGACTGGTCA
TCGCCTCACGGGCACAGACCAACTTTGCCCGCCTGCTGGCAGGCTCTATTACCCTGACCTTCTTCGTGTATATCTTCGTG
AATATCGGCATGGTCAGCGGCATTTTGCCCGTGGTGGGTGTGCCCTTGCCCCTGATTAGCTATGGCGGCACCTCGATGCT
GACATTGATGACAGGTTTTGGCATTCTAATGAGCATTCAAACCCACAGGCGCTTTGTCGACCGCTAA

Upstream 100 bases:

>100_bases
TGGTATTGGAGAACGCTGGTTGGGGCGGCGCCAATGCCGGTCCTGTGGCACGCGCCATGCTGGATGAATTTATGCTCCAT
GAGCAGTGGAAGGTGCAACC

Downstream 100 bases:

>100_bases
GGAATGCCGATGAGTTTTGCCCCAGGCCTGGCCTTGTTGTCAGGCCTTCTTGCCGCCAATCTTGTGCTCGCTGCCGAGAC
ACAAATCGACACTGCCAGGG

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MTRDHARKNIWQRMHIDLPLLLGLLAIMGFGLFVIWSASGEDPAMLERQLVRMGLSLGIMLFMAQINPEILRRWALPIYI
AGIILLLGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAFPITMAWFISKFTLPPKKRYLAAAAVIMLIPTLLIAKQPDL
GTSILVAASGIFVLFLSGMSWYIVLGLLASVLSFLPILWYFLMHDYQRRRVLTLLDPEKDPLGAGYHIIQSKIAIGSGGV
DGKGWLHGTQSQLEFLPERHTDFIFAVIGEEFGLIGAIVLLAMYIYVIGRGLVIASRAQTNFARLLAGSITLTFFVYIFV
NIGMVSGILPVVGVPLPLISYGGTSMLTLMTGFGILMSIQTHRRFVDR

Sequences:

>Translated_368_residues
MTRDHARKNIWQRMHIDLPLLLGLLAIMGFGLFVIWSASGEDPAMLERQLVRMGLSLGIMLFMAQINPEILRRWALPIYI
AGIILLLGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAFPITMAWFISKFTLPPKKRYLAAAAVIMLIPTLLIAKQPDL
GTSILVAASGIFVLFLSGMSWYIVLGLLASVLSFLPILWYFLMHDYQRRRVLTLLDPEKDPLGAGYHIIQSKIAIGSGGV
DGKGWLHGTQSQLEFLPERHTDFIFAVIGEEFGLIGAIVLLAMYIYVIGRGLVIASRAQTNFARLLAGSITLTFFVYIFV
NIGMVSGILPVVGVPLPLISYGGTSMLTLMTGFGILMSIQTHRRFVDR
>Mature_367_residues
TRDHARKNIWQRMHIDLPLLLGLLAIMGFGLFVIWSASGEDPAMLERQLVRMGLSLGIMLFMAQINPEILRRWALPIYIA
GIILLLGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAFPITMAWFISKFTLPPKKRYLAAAAVIMLIPTLLIAKQPDLG
TSILVAASGIFVLFLSGMSWYIVLGLLASVLSFLPILWYFLMHDYQRRRVLTLLDPEKDPLGAGYHIIQSKIAIGSGGVD
GKGWLHGTQSQLEFLPERHTDFIFAVIGEEFGLIGAIVLLAMYIYVIGRGLVIASRAQTNFARLLAGSITLTFFVYIFVN
IGMVSGILPVVGVPLPLISYGGTSMLTLMTGFGILMSIQTHRRFVDR

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=368, Percent_Identity=60.8695652173913, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1786277, Length=302, Percent_Identity=35.7615894039735, Blast_Score=167, Evalue=9e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40983; Mature: 40852

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRDHARKNIWQRMHIDLPLLLGLLAIMGFGLFVIWSASGEDPAMLERQLVRMGLSLGIM
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHH
LFMAQINPEILRRWALPIYIAGIILLLGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECHHHHHHHHH
PITMAWFISKFTLPPKKRYLAAAAVIMLIPTLLIAKQPDLGTSILVAASGIFVLFLSGMS
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHH
WYIVLGLLASVLSFLPILWYFLMHDYQRRRVLTLLDPEKDPLGAGYHIIQSKIAIGSGGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHEECCCCC
DGKGWLHGTQSQLEFLPERHTDFIFAVIGEEFGLIGAIVLLAMYIYVIGRGLVIASRAQT
CCCCCCCCCHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHH
NFARLLAGSITLTFFVYIFVNIGMVSGILPVVGVPLPLISYGGTSMLTLMTGFGILMSIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHH
THRRFVDR
HHHHHCCC
>Mature Secondary Structure 
TRDHARKNIWQRMHIDLPLLLGLLAIMGFGLFVIWSASGEDPAMLERQLVRMGLSLGIM
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHH
LFMAQINPEILRRWALPIYIAGIILLLGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECHHHHHHHHH
PITMAWFISKFTLPPKKRYLAAAAVIMLIPTLLIAKQPDLGTSILVAASGIFVLFLSGMS
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHH
WYIVLGLLASVLSFLPILWYFLMHDYQRRRVLTLLDPEKDPLGAGYHIIQSKIAIGSGGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHEECCCCC
DGKGWLHGTQSQLEFLPERHTDFIFAVIGEEFGLIGAIVLLAMYIYVIGRGLVIASRAQT
CCCCCCCCCHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHH
NFARLLAGSITLTFFVYIFVNIGMVSGILPVVGVPLPLISYGGTSMLTLMTGFGILMSIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHH
THRRFVDR
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]