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The map label for this gene is yggW [H]

Identifier: 119775616

GI number: 119775616

Start: 2984015

End: 2985154

Strand: Direct

Name: yggW [H]

Synonym: Sama_2483

Alternate gene names: 119775616

Gene position: 2984015-2985154 (Clockwise)

Preceding gene: 119775615

Following gene: 119775617

Centisome position: 69.3

GC content: 54.21

Gene sequence:

>1140_bases
GTGAAGCTTGAACTGCCTCCTCTGAGCCTTTATGTCCACATCCCCTGGTGTGTGCAAAAATGCCCCTATTGCGACTTTAA
CTCCCACGGAAAACAAGGCGATTTACCCCAGGAAGCCTACGTCGATGCGCTGCTGGCAGACCTTGATGCCGATTTGAATT
ATGTCCAGGGACGTACGCTTTACAGCATTTTCATCGGCGGCGGCACCCCGTCGCTGTTTGATGCCAGCGCCATCGGCCGC
CTCCTCGACGGTATTAAGGCCCGCATCCCCTTTTGTGATGACATAGAAATCACCATGGAAGCCAATCCGGGCACTCTGGA
GCACGATGATTTCAGCGCTTACCGCGGGGCAGGCGTCACCCGCCTCTCAGTGGGCGTACAGAGCTTCAGCAAGGACAAGC
TTAACCTCCTTGGCCGCATTCACGGGCGCGATGAGGCAACCCGGGCGGCAGAGCTTGCCACTGCCGCTGGCTATCAGAGC
TTTAACCTGGATTTGATGCATGGTCTGCCCAATCAATCATTTGATGAGGCCATGGCCGATATAGACACGGCGGCCAGCCT
AAATCCTCCCCATCTGTCCTGGTATCAGCTCACCATCGAGCCAAATACTCTGTTTCACTCGCGGCCTCCGCAGTTGCCGG
ACGACGAAGCGCTTTGGCATATCTACGAACAAGGCCAGAAAAAGCTCGCGGCCCTGGGATATGAGCAGTATGAGATTTCA
GCCTACGCCAAACCGGGCTTTCAATGCCGTCATAATCTCAATTACTGGCAGTTTGGTGACTACCTCGGTATTGGCTGCGG
AGCCCACGGCAAGGTGACGATCCCCACCGAAAACTGCATTATTCGAACGGTAAAAATAAAACATCCCAAGGGATACCTGG
CAGCCAGCGATTATCTGTCTGAACTGACACAAGTGCAGGAAGAAGACCGCCCACTTGAATTTTTGATGAACCGCTTGAGG
CTGATGACCCCCATCGCCAAACGTGAATTTGAATCCCGCACCGGCCTGAATGCCAGCCTGCTTGATGAAGGGATGGCACA
GGCGAGCGAAAAAGGCCTTATCGTACTTGGCGACGAGAGTTGGACCCTGACCCCAAAGGGCCACATGTTCGTTAACGACT
TACTGTCCCATTTTCTCTGA

Upstream 100 bases:

>100_bases
GATGTCATCGGATGCGAAAAATGCTGTGAGCCACCGCGGCAAGGCCCTTGAAGCGCTGCTGGCTGAGTTCAGAAACAAAG
GCATCATCTGAGGAAAGACC

Downstream 100 bases:

>100_bases
CCCACACAATCATCTGGATTGCCCCAGAGGCAGGCCTATAAATGCCTGCCTCTGGGAACCGGGAAACATTTACTAACACT
AAACTCTGAAATTTACCCAT

Product: oxygen-independent coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKLELPPLSLYVHIPWCVQKCPYCDFNSHGKQGDLPQEAYVDALLADLDADLNYVQGRTLYSIFIGGGTPSLFDASAIGR
LLDGIKARIPFCDDIEITMEANPGTLEHDDFSAYRGAGVTRLSVGVQSFSKDKLNLLGRIHGRDEATRAAELATAAGYQS
FNLDLMHGLPNQSFDEAMADIDTAASLNPPHLSWYQLTIEPNTLFHSRPPQLPDDEALWHIYEQGQKKLAALGYEQYEIS
AYAKPGFQCRHNLNYWQFGDYLGIGCGAHGKVTIPTENCIIRTVKIKHPKGYLAASDYLSELTQVQEEDRPLEFLMNRLR
LMTPIAKREFESRTGLNASLLDEGMAQASEKGLIVLGDESWTLTPKGHMFVNDLLSHFL

Sequences:

>Translated_379_residues
MKLELPPLSLYVHIPWCVQKCPYCDFNSHGKQGDLPQEAYVDALLADLDADLNYVQGRTLYSIFIGGGTPSLFDASAIGR
LLDGIKARIPFCDDIEITMEANPGTLEHDDFSAYRGAGVTRLSVGVQSFSKDKLNLLGRIHGRDEATRAAELATAAGYQS
FNLDLMHGLPNQSFDEAMADIDTAASLNPPHLSWYQLTIEPNTLFHSRPPQLPDDEALWHIYEQGQKKLAALGYEQYEIS
AYAKPGFQCRHNLNYWQFGDYLGIGCGAHGKVTIPTENCIIRTVKIKHPKGYLAASDYLSELTQVQEEDRPLEFLMNRLR
LMTPIAKREFESRTGLNASLLDEGMAQASEKGLIVLGDESWTLTPKGHMFVNDLLSHFL
>Mature_379_residues
MKLELPPLSLYVHIPWCVQKCPYCDFNSHGKQGDLPQEAYVDALLADLDADLNYVQGRTLYSIFIGGGTPSLFDASAIGR
LLDGIKARIPFCDDIEITMEANPGTLEHDDFSAYRGAGVTRLSVGVQSFSKDKLNLLGRIHGRDEATRAAELATAAGYQS
FNLDLMHGLPNQSFDEAMADIDTAASLNPPHLSWYQLTIEPNTLFHSRPPQLPDDEALWHIYEQGQKKLAALGYEQYEIS
AYAKPGFQCRHNLNYWQFGDYLGIGCGAHGKVTIPTENCIIRTVKIKHPKGYLAASDYLSELTQVQEEDRPLEFLMNRLR
LMTPIAKREFESRTGLNASLLDEGMAQASEKGLIVLGDESWTLTPKGHMFVNDLLSHFL

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=283, Percent_Identity=33.2155477031802, Blast_Score=163, Evalue=3e-40,
Organism=Escherichia coli, GI1789325, Length=377, Percent_Identity=58.8859416445623, Blast_Score=471, Evalue=1e-134,
Organism=Escherichia coli, GI87082341, Length=242, Percent_Identity=30.1652892561983, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 42255; Mature: 42255

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLELPPLSLYVHIPWCVQKCPYCDFNSHGKQGDLPQEAYVDALLADLDADLNYVQGRTL
CCCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCEE
YSIFIGGGTPSLFDASAIGRLLDGIKARIPFCDDIEITMEANPGTLEHDDFSAYRGAGVT
EEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHCCCEE
RLSVGVQSFSKDKLNLLGRIHGRDEATRAAELATAAGYQSFNLDLMHGLPNQSFDEAMAD
EEEHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEHCCCCCCCCHHHHHHH
IDTAASLNPPHLSWYQLTIEPNTLFHSRPPQLPDDEALWHIYEQGQKKLAALGYEQYEIS
HHHHCCCCCCCCEEEEEEECCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEE
AYAKPGFQCRHNLNYWQFGDYLGIGCGAHGKVTIPTENCIIRTVKIKHPKGYLAASDYLS
EECCCCCCCCCCCCCEECCCEEEECCCCCCEEEECCCCEEEEEEEEECCCCCCHHHHHHH
ELTQVQEEDRPLEFLMNRLRLMTPIAKREFESRTGLNASLLDEGMAQASEKGLIVLGDES
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCC
WTLTPKGHMFVNDLLSHFL
EEECCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKLELPPLSLYVHIPWCVQKCPYCDFNSHGKQGDLPQEAYVDALLADLDADLNYVQGRTL
CCCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCEE
YSIFIGGGTPSLFDASAIGRLLDGIKARIPFCDDIEITMEANPGTLEHDDFSAYRGAGVT
EEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHCCCEE
RLSVGVQSFSKDKLNLLGRIHGRDEATRAAELATAAGYQSFNLDLMHGLPNQSFDEAMAD
EEEHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEHCCCCCCCCHHHHHHH
IDTAASLNPPHLSWYQLTIEPNTLFHSRPPQLPDDEALWHIYEQGQKKLAALGYEQYEIS
HHHHCCCCCCCCEEEEEEECCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEE
AYAKPGFQCRHNLNYWQFGDYLGIGCGAHGKVTIPTENCIIRTVKIKHPKGYLAASDYLS
EECCCCCCCCCCCCCEECCCEEEECCCCCCEEEECCCCEEEEEEEEECCCCCCHHHHHHH
ELTQVQEEDRPLEFLMNRLRLMTPIAKREFESRTGLNASLLDEGMAQASEKGLIVLGDES
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCC
WTLTPKGHMFVNDLLSHFL
EEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]