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The map label for this gene is yggV [C]

Identifier: 119775615

GI number: 119775615

Start: 2983409

End: 2984005

Strand: Direct

Name: yggV [C]

Synonym: Sama_2482

Alternate gene names: 119775615

Gene position: 2983409-2984005 (Clockwise)

Preceding gene: 119775614

Following gene: 119775616

Centisome position: 69.28

GC content: 54.77

Gene sequence:

>597_bases
ATGAAGAAAGTGGTTCTCGCCAGTGGTAACAAGGGTAAACTGAAAGAATTCAATGAGATGTTTTCTGAGTATTCACTCTC
GGTAGTAGCCCAGAGCGAGTTTCAGGTGCCAGACGTTGAAGAAACCGGCACTACCTTCGTCGAAAACGCCATCATTAAAG
CCCGCCATGCTGCAGCTATTACCGGCTTACCCGCCATTGCCGACGACTCGGGGTTGGAAGTAGACGCCCTCGAAGGTGCC
CCTGGTATTTACTCTGCCCGCTACGCAGGCGTTGGCGCTAAAGATACAGACAATTGGCAAAAGCTGCTGGGTGCCCTCGA
AGGCAAAACCGAGCGCAGTGCCCGCTTCCAGTGTGTACTCGTGTATATGCGCCATGCCAAAGACCCAACCCCCATTATCT
GCCAGGCTGCCTGGGAAGGACGTATCGGTCTCGAAGCCAGGGGCGATAATGGCCATGGTTACGACCCTGTGTTTATCGCC
GAAGGCGGCGAGCTGACCGCAGCCCAGATGTCATCGGATGCGAAAAATGCTGTGAGCCACCGCGGCAAGGCCCTTGAAGC
GCTGCTGGCTGAGTTCAGAAACAAAGGCATCATCTGA

Upstream 100 bases:

>100_bases
GGGCTTTGTTTTTTCTGTCTTTCCAAGGCTTCCTTGGGTATCATGACGCCGATTTTGAAAGGGCGCAGTGCGCCAACAGC
ACAGTGGTCAGGGGGTAATG

Downstream 100 bases:

>100_bases
GGAAAGACCGTGAAGCTTGAACTGCCTCCTCTGAGCCTTTATGTCCACATCCCCTGGTGTGTGCAAAAATGCCCCTATTG
CGACTTTAACTCCCACGGAA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MKKVVLASGNKGKLKEFNEMFSEYSLSVVAQSEFQVPDVEETGTTFVENAIIKARHAAAITGLPAIADDSGLEVDALEGA
PGIYSARYAGVGAKDTDNWQKLLGALEGKTERSARFQCVLVYMRHAKDPTPIICQAAWEGRIGLEARGDNGHGYDPVFIA
EGGELTAAQMSSDAKNAVSHRGKALEALLAEFRNKGII

Sequences:

>Translated_198_residues
MKKVVLASGNKGKLKEFNEMFSEYSLSVVAQSEFQVPDVEETGTTFVENAIIKARHAAAITGLPAIADDSGLEVDALEGA
PGIYSARYAGVGAKDTDNWQKLLGALEGKTERSARFQCVLVYMRHAKDPTPIICQAAWEGRIGLEARGDNGHGYDPVFIA
EGGELTAAQMSSDAKNAVSHRGKALEALLAEFRNKGII
>Mature_198_residues
MKKVVLASGNKGKLKEFNEMFSEYSLSVVAQSEFQVPDVEETGTTFVENAIIKARHAAAITGLPAIADDSGLEVDALEGA
PGIYSARYAGVGAKDTDNWQKLLGALEGKTERSARFQCVLVYMRHAKDPTPIICQAAWEGRIGLEARGDNGHGYDPVFIA
EGGELTAAQMSSDAKNAVSHRGKALEALLAEFRNKGII

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=196, Percent_Identity=55.1020408163265, Blast_Score=226, Evalue=7e-61,
Organism=Caenorhabditis elegans, GI17556833, Length=196, Percent_Identity=29.0816326530612, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI19920712, Length=194, Percent_Identity=29.3814432989691, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21213; Mature: 21213

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVVLASGNKGKLKEFNEMFSEYSLSVVAQSEFQVPDVEETGTTFVENAIIKARHAAAI
CCEEEEECCCCCCHHHHHHHHHHHCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
TGLPAIADDSGLEVDALEGAPGIYSARYAGVGAKDTDNWQKLLGALEGKTERSARFQCVL
CCCCCCCCCCCCEEEECCCCCCCCCHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHE
VYMRHAKDPTPIICQAAWEGRIGLEARGDNGHGYDPVFIAEGGELTAAQMSSDAKNAVSH
EEHHHCCCCCCEEEEECCCCCCCEEEECCCCCCCCCEEEECCCCEEHHHHCCHHHHHHHH
RGKALEALLAEFRNKGII
CHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKVVLASGNKGKLKEFNEMFSEYSLSVVAQSEFQVPDVEETGTTFVENAIIKARHAAAI
CCEEEEECCCCCCHHHHHHHHHHHCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
TGLPAIADDSGLEVDALEGAPGIYSARYAGVGAKDTDNWQKLLGALEGKTERSARFQCVL
CCCCCCCCCCCCEEEECCCCCCCCCHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHE
VYMRHAKDPTPIICQAAWEGRIGLEARGDNGHGYDPVFIAEGGELTAAQMSSDAKNAVSH
EEHHHCCCCCCEEEEECCCCCCCEEEECCCCCCCCCEEEECCCCEEHHHHCCHHHHHHHH
RGKALEALLAEFRNKGII
CHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]