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The map label for this gene is rlmM

Identifier: 119775560

GI number: 119775560

Start: 2920901

End: 2921986

Strand: Reverse

Name: rlmM

Synonym: Sama_2426

Alternate gene names: 119775560

Gene position: 2921986-2920901 (Counterclockwise)

Preceding gene: 119775561

Following gene: 119775556

Centisome position: 67.86

GC content: 51.84

Gene sequence:

>1086_bases
ATGAAAAACCTGTTCTTATATTGCCGTGCCGGTTATGAAAAAGACTGTGCGGCTGAAATTCAGCAGCGGGCCGCCGAGCT
CGGCATTGGTGGTTTCGTCAAAGCCAACCGCGACGATGCTTATGTGGTATTTCAGGGATTCAGCCCTGATGATGGTGATC
GCCTCGCCAAAGAATTGCCTCTGGACTCGCTGATTTTTGCCCGGCAGATGTTCGCCTGTGGCGATTTGCTTGATGACTTT
TCACCTGAAGACAGGGTTACCCCTATTGCTGAGAGCCTGACGGAAGTTGAACGGGCAGGGGAACTGCGGGTAGAAACCCC
AGATACCAATGAAGCCAAAGAGCTTTCTGCCTTCTGCCGTAAATTCACAGTGCCCCTGCGTCAGGCATTGAAAAAGCGTG
GTGTGCTGCTGGACAAAGAAAGCAGCCGTCGTCCCATAGTGCATGTGTGCTTTGTGGCGCCCAACAAGGCTTTTACCGGT
TATTCGTTGTCAAACAACAGCTCTCCACACTTTATGGGGATCCCGCGGCTAAAATTTCCGGCGGACGCTCCGAGTCGTTC
GACCCTTAAATTGGACGAAGCCTTTATCCATTTTATTCCCCGTGAAGAGCACGAAACCCGTCTTCGCAGTGGACTCAATG
CGGTGGATTTGGGCGCTTGTCCCGGTGGCTGGACTTATCAATTGGTGCGCCGTGGCATGATGGTGCACGCCATCGATAAT
GGCCCCATGAACCATGATCTGATGGAAACCGGACAGGTGACGCACCACCGCGCTGACGGTTTCAAATTTGAGCCAGCCCG
CCGTAATATCTACTGGCTGGTATGTGACATGGTGGAAAAGCCTGCCCGTGTGGCTGAATTGATGGAATACTGGGCGATTC
AGGGCTGGTTTAAAGAGGCGATTTTTAACCTCAAACTACCGATGAAAAGCCGCTACAAAGAGGTGTCGCAGATCCTCGCC
AATATGCATGCCATCCTTAAGGAAAATGGCATTCACGAGTTTCATCTGGCCTGTAAGCACCTTTATCACGATCGTGACGA
AGTGACTGTACACCTGTGGCTCCGCCCAAGTTCACCTTGGATTTGA

Upstream 100 bases:

>100_bases
GCAAATAGCCAAGAGATGGCCGCGCTGTGATATACTCGGCGCCAATTTCTGATTTTGCGGCCTTTGGGCCGCTTTATGTT
AGCGCCAACGAAGAATCGCA

Downstream 100 bases:

>100_bases
TAGTCGGATCAAGGCTTGCTCGAGCACAAATAAAGGCGCCCAATGGCGCCTTTATTTTATCTGGGTACTCCATTTGAACA
CTATGCAAAAGTCGGTAACG

Product: putative RNA 2'-O-ribose methyltransferase

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MKNLFLYCRAGYEKDCAAEIQQRAAELGIGGFVKANRDDAYVVFQGFSPDDGDRLAKELPLDSLIFARQMFACGDLLDDF
SPEDRVTPIAESLTEVERAGELRVETPDTNEAKELSAFCRKFTVPLRQALKKRGVLLDKESSRRPIVHVCFVAPNKAFTG
YSLSNNSSPHFMGIPRLKFPADAPSRSTLKLDEAFIHFIPREEHETRLRSGLNAVDLGACPGGWTYQLVRRGMMVHAIDN
GPMNHDLMETGQVTHHRADGFKFEPARRNIYWLVCDMVEKPARVAELMEYWAIQGWFKEAIFNLKLPMKSRYKEVSQILA
NMHAILKENGIHEFHLACKHLYHDRDEVTVHLWLRPSSPWI

Sequences:

>Translated_361_residues
MKNLFLYCRAGYEKDCAAEIQQRAAELGIGGFVKANRDDAYVVFQGFSPDDGDRLAKELPLDSLIFARQMFACGDLLDDF
SPEDRVTPIAESLTEVERAGELRVETPDTNEAKELSAFCRKFTVPLRQALKKRGVLLDKESSRRPIVHVCFVAPNKAFTG
YSLSNNSSPHFMGIPRLKFPADAPSRSTLKLDEAFIHFIPREEHETRLRSGLNAVDLGACPGGWTYQLVRRGMMVHAIDN
GPMNHDLMETGQVTHHRADGFKFEPARRNIYWLVCDMVEKPARVAELMEYWAIQGWFKEAIFNLKLPMKSRYKEVSQILA
NMHAILKENGIHEFHLACKHLYHDRDEVTVHLWLRPSSPWI
>Mature_361_residues
MKNLFLYCRAGYEKDCAAEIQQRAAELGIGGFVKANRDDAYVVFQGFSPDDGDRLAKELPLDSLIFARQMFACGDLLDDF
SPEDRVTPIAESLTEVERAGELRVETPDTNEAKELSAFCRKFTVPLRQALKKRGVLLDKESSRRPIVHVCFVAPNKAFTG
YSLSNNSSPHFMGIPRLKFPADAPSRSTLKLDEAFIHFIPREEHETRLRSGLNAVDLGACPGGWTYQLVRRGMMVHAIDN
GPMNHDLMETGQVTHHRADGFKFEPARRNIYWLVCDMVEKPARVAELMEYWAIQGWFKEAIFNLKLPMKSRYKEVSQILA
NMHAILKENGIHEFHLACKHLYHDRDEVTVHLWLRPSSPWI

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily

Homologues:

Organism=Escherichia coli, GI1789171, Length=353, Percent_Identity=60.6232294617564, Blast_Score=446, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMM_SHEAM (A1S8C4)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_928300.1
- ProteinModelPortal:   A1S8C4
- SMR:   A1S8C4
- STRING:   A1S8C4
- GeneID:   4604675
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_2426
- NMPDR:   fig|326297.7.peg.2271
- eggNOG:   COG2933
- HOGENOM:   HBG681972
- OMA:   LYCRPGF
- PhylomeDB:   A1S8C4
- ProtClustDB:   PRK11760
- GO:   GO:0005737
- HAMAP:   MF_01551
- InterPro:   IPR011224
- InterPro:   IPR002877
- PIRSF:   PIRSF028774

Pfam domain/function: PF01728 FtsJ

EC number: NA

Molecular weight: Translated: 41220; Mature: 41220

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLFLYCRAGYEKDCAAEIQQRAAELGIGGFVKANRDDAYVVFQGFSPDDGDRLAKELP
CCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCCCHHHHHHHCC
LDSLIFARQMFACGDLLDDFSPEDRVTPIAESLTEVERAGELRVETPDTNEAKELSAFCR
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHH
KFTVPLRQALKKRGVLLDKESSRRPIVHVCFVAPNKAFTGYSLSNNSSPHFMGIPRLKFP
HHHHHHHHHHHHCCCEECCCCCCCCEEEEEEECCCCCCCCEECCCCCCCCEECCCCEECC
ADAPSRSTLKLDEAFIHFIPREEHETRLRSGLNAVDLGACPGGWTYQLVRRGMMVHAIDN
CCCCCCCEEEHHHHHHHHCCCCHHHHHHHCCCCEEECCCCCCCHHHHHHHCCCEEEEECC
GPMNHDLMETGQVTHHRADGFKFEPARRNIYWLVCDMVEKPARVAELMEYWAIQGWFKEA
CCCCCHHHHCCCCCEECCCCCEECCCCCCEEEEEEHHHHCHHHHHHHHHHHHHHHHHHHH
IFNLKLPMKSRYKEVSQILANMHAILKENGIHEFHLACKHLYHDRDEVTVHLWLRPSSPW
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCC
I
C
>Mature Secondary Structure
MKNLFLYCRAGYEKDCAAEIQQRAAELGIGGFVKANRDDAYVVFQGFSPDDGDRLAKELP
CCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCCCHHHHHHHCC
LDSLIFARQMFACGDLLDDFSPEDRVTPIAESLTEVERAGELRVETPDTNEAKELSAFCR
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHH
KFTVPLRQALKKRGVLLDKESSRRPIVHVCFVAPNKAFTGYSLSNNSSPHFMGIPRLKFP
HHHHHHHHHHHHCCCEECCCCCCCCEEEEEEECCCCCCCCEECCCCCCCCEECCCCEECC
ADAPSRSTLKLDEAFIHFIPREEHETRLRSGLNAVDLGACPGGWTYQLVRRGMMVHAIDN
CCCCCCCEEEHHHHHHHHCCCCHHHHHHHCCCCEEECCCCCCCHHHHHHHCCCEEEEECC
GPMNHDLMETGQVTHHRADGFKFEPARRNIYWLVCDMVEKPARVAELMEYWAIQGWFKEA
CCCCCHHHHCCCCCEECCCCCEECCCCCCEEEEEEHHHHCHHHHHHHHHHHHHHHHHHHH
IFNLKLPMKSRYKEVSQILANMHAILKENGIHEFHLACKHLYHDRDEVTVHLWLRPSSPW
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA