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The map label for this gene is engA

Identifier: 119775495

GI number: 119775495

Start: 2837253

End: 2838719

Strand: Reverse

Name: engA

Synonym: Sama_2361

Alternate gene names: 119775495

Gene position: 2838719-2837253 (Counterclockwise)

Preceding gene: 119775496

Following gene: 119775493

Centisome position: 65.92

GC content: 56.85

Gene sequence:

>1467_bases
ATGATCCCTGTAGTGGCCCTGGTGGGTCGCCCCAACGTGGGCAAATCGACCCTGTTTAACCGACTCACGAGAACCCGGGA
TGCCTTGGTGGCGGATTATCCGGGGCTGACCCGTGACCGCAAATACGGCCGGGCTCATCTGTCTGGCTATGAATTTATCG
TGGTGGATACCGGCGGTATCGACGGCACCGAAGAAGGCATCGAGACCAAGATGGCCGAGCAGTCATTGGCGGCCATCGAA
GAAGCCGATGTGGTGCTGTTTATGACCGACGCCCGCGCCGGTCTGACTGCCGCTGACCTGGCCATTGCCCAGCACCTGCG
CAGCCGCGATAAAATCACTTTCGTAGTGGCCAACAAGGTGGATGGCATCGATGCCGACTCTGCCTGTGGCGAATTTTGGC
AGCTGGGTCTGGGCGAGGTGTACCAGATGGCCGCCGCACAGGGCCGTGGTGTAACTGGCTTGGTGGAATATGCTCTGGCG
CCTTTTGCCGAAGCCATGGGACTGGTCCGTGACGACGACGGCGAAGTGGTGACAGATGAGCGCAACTACACCGAAGAAGA
AGCCGAAGCCGAACAGCAACGTCTGGCGGAGCAGCCCATTAAGTTGGCCATTATCGGTAAGCCCAATGTGGGCAAGTCCA
CCCTGACCAACCGTATTTTGGGTGAAGAGCGGGTTGTGGTATACGACCAGCCCGGCACGACCCGTGACTCGGTATACATC
CCCATGGAGCGTGACGGCCGTAACTATGTGCTTATCGATACTGCCGGTGTGCGTCGTCGTGCCCGCGTGCATGAAGTGAT
TGAAAAGTTCTCTGTTATCAAGACACTCAAGGCCGTGGAAGACTCCAACGTCGTGCTGCTGGTTATCGATGCCCATGAAG
GCATTGCCGAGCAGGATCTGGGACTCCTGGGCTTTGTGCTCAACTCAGGCCGCGCTCTGGTACTTGCAGTCAACAAGTGG
GATGGTTTGGATCAAGACGTCAAAGACAGGGTGAAAACCGAGCTCGACCGTCGTCTGGGCTTTATCGACTTTGCCCGTAT
CCACTTTATTTCTGCGCTCCATGGTACAGGCGTTGGTCACTTGTTTGAGTCTATCGAAGAGGCCTACGACAGTGCGACCC
GCCGTGTGAGCACTTCCATGCTGACCCGTATCATGCAGATGGCGCAGGACGATCACCAACCGCCGATGGTGAATGGTCGC
CGCGTGAAGCTCAAATACGCCCACGTGGGAGGCTACAATCCGCCTATCGTGGTAGTACACGGCAACCAGGTAAGCCGACT
GCCGGATTCTTACAAGCGTTACATGATGAACTACTATCGTCGCGCGCTTAAGGTTGTGGGTACCCCAATCCAGCTGCGCT
TCCATGAGGGTGATAACCCGTTCGAAGGCCGTAAGGAAAAACTGACTCTGAGCCAGGAGCGTCGCCGTAAGCGGATGATG
AGCCATATCAAGAGCAAGAAAGCCTGA

Upstream 100 bases:

>100_bases
CCCGCATCGCACTTCCTTAAGTCAAGGTTTAACCTTGCCAAGCCCCTGGAAGTGTGTTCCGGGGGCTTTTTATTGAAAAG
ATTGTTATAGAGGCAAAAGC

Downstream 100 bases:

>100_bases
TGTTGCCTGTTGGCAACCAGTCGGACTGAAGCGTCAATAAAAAAGCCGGGCATATGCCTGGCTTTTTTATGCTCTTCGCG
GGCATGAAAATCTTTACTCC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADYPGLTRDRKYGRAHLSGYEFIVVDTGGIDGTEEGIETKMAEQSLAAIE
EADVVLFMTDARAGLTAADLAIAQHLRSRDKITFVVANKVDGIDADSACGEFWQLGLGEVYQMAAAQGRGVTGLVEYALA
PFAEAMGLVRDDDGEVVTDERNYTEEEAEAEQQRLAEQPIKLAIIGKPNVGKSTLTNRILGEERVVVYDQPGTTRDSVYI
PMERDGRNYVLIDTAGVRRRARVHEVIEKFSVIKTLKAVEDSNVVLLVIDAHEGIAEQDLGLLGFVLNSGRALVLAVNKW
DGLDQDVKDRVKTELDRRLGFIDFARIHFISALHGTGVGHLFESIEEAYDSATRRVSTSMLTRIMQMAQDDHQPPMVNGR
RVKLKYAHVGGYNPPIVVVHGNQVSRLPDSYKRYMMNYYRRALKVVGTPIQLRFHEGDNPFEGRKEKLTLSQERRRKRMM
SHIKSKKA

Sequences:

>Translated_488_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADYPGLTRDRKYGRAHLSGYEFIVVDTGGIDGTEEGIETKMAEQSLAAIE
EADVVLFMTDARAGLTAADLAIAQHLRSRDKITFVVANKVDGIDADSACGEFWQLGLGEVYQMAAAQGRGVTGLVEYALA
PFAEAMGLVRDDDGEVVTDERNYTEEEAEAEQQRLAEQPIKLAIIGKPNVGKSTLTNRILGEERVVVYDQPGTTRDSVYI
PMERDGRNYVLIDTAGVRRRARVHEVIEKFSVIKTLKAVEDSNVVLLVIDAHEGIAEQDLGLLGFVLNSGRALVLAVNKW
DGLDQDVKDRVKTELDRRLGFIDFARIHFISALHGTGVGHLFESIEEAYDSATRRVSTSMLTRIMQMAQDDHQPPMVNGR
RVKLKYAHVGGYNPPIVVVHGNQVSRLPDSYKRYMMNYYRRALKVVGTPIQLRFHEGDNPFEGRKEKLTLSQERRRKRMM
SHIKSKKA
>Mature_488_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADYPGLTRDRKYGRAHLSGYEFIVVDTGGIDGTEEGIETKMAEQSLAAIE
EADVVLFMTDARAGLTAADLAIAQHLRSRDKITFVVANKVDGIDADSACGEFWQLGLGEVYQMAAAQGRGVTGLVEYALA
PFAEAMGLVRDDDGEVVTDERNYTEEEAEAEQQRLAEQPIKLAIIGKPNVGKSTLTNRILGEERVVVYDQPGTTRDSVYI
PMERDGRNYVLIDTAGVRRRARVHEVIEKFSVIKTLKAVEDSNVVLLVIDAHEGIAEQDLGLLGFVLNSGRALVLAVNKW
DGLDQDVKDRVKTELDRRLGFIDFARIHFISALHGTGVGHLFESIEEAYDSATRRVSTSMLTRIMQMAQDDHQPPMVNGR
RVKLKYAHVGGYNPPIVVVHGNQVSRLPDSYKRYMMNYYRRALKVVGTPIQLRFHEGDNPFEGRKEKLTLSQERRRKRMM
SHIKSKKA

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=493, Percent_Identity=69.9797160243408, Blast_Score=707, Evalue=0.0,
Organism=Escherichia coli, GI2367268, Length=103, Percent_Identity=35.9223300970874, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=189, Percent_Identity=27.5132275132275, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_SHEAM (A1S859)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_928235.1
- ProteinModelPortal:   A1S859
- SMR:   A1S859
- STRING:   A1S859
- GeneID:   4604610
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_2361
- NMPDR:   fig|326297.7.peg.2211
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- PhylomeDB:   A1S859
- ProtClustDB:   PRK00093
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 54438; Mature: 54438

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADYPGLTRDRKYGRAHLSGYEFIVVDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCEEEEEEECCCC
DGTEEGIETKMAEQSLAAIEEADVVLFMTDARAGLTAADLAIAQHLRSRDKITFVVANKV
CCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCC
DGIDADSACGEFWQLGLGEVYQMAAAQGRGVTGLVEYALAPFAEAMGLVRDDDGEVVTDE
CCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEECCCCCEEECC
RNYTEEEAEAEQQRLAEQPIKLAIIGKPNVGKSTLTNRILGEERVVVYDQPGTTRDSVYI
CCCCHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCCCEEE
PMERDGRNYVLIDTAGVRRRARVHEVIEKFSVIKTLKAVEDSNVVLLVIDAHEGIAEQDL
EEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHCC
GLLGFVLNSGRALVLAVNKWDGLDQDVKDRVKTELDRRLGFIDFARIHFISALHGTGVGH
HHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHH
LFESIEEAYDSATRRVSTSMLTRIMQMAQDDHQPPMVNGRRVKLKYAHVGGYNPPIVVVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCEEEEE
GNQVSRLPDSYKRYMMNYYRRALKVVGTPIQLRFHEGDNPFEGRKEKLTLSQERRRKRMM
CCCHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHCCHHHHHHHHHHH
SHIKSKKA
HHHHHCCC
>Mature Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADYPGLTRDRKYGRAHLSGYEFIVVDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCEEEEEEECCCC
DGTEEGIETKMAEQSLAAIEEADVVLFMTDARAGLTAADLAIAQHLRSRDKITFVVANKV
CCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCC
DGIDADSACGEFWQLGLGEVYQMAAAQGRGVTGLVEYALAPFAEAMGLVRDDDGEVVTDE
CCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEECCCCCEEECC
RNYTEEEAEAEQQRLAEQPIKLAIIGKPNVGKSTLTNRILGEERVVVYDQPGTTRDSVYI
CCCCHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCCCEEE
PMERDGRNYVLIDTAGVRRRARVHEVIEKFSVIKTLKAVEDSNVVLLVIDAHEGIAEQDL
EEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHCC
GLLGFVLNSGRALVLAVNKWDGLDQDVKDRVKTELDRRLGFIDFARIHFISALHGTGVGH
HHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHH
LFESIEEAYDSATRRVSTSMLTRIMQMAQDDHQPPMVNGRRVKLKYAHVGGYNPPIVVVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCEEEEE
GNQVSRLPDSYKRYMMNYYRRALKVVGTPIQLRFHEGDNPFEGRKEKLTLSQERRRKRMM
CCCHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHCCHHHHHHHHHHH
SHIKSKKA
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA