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The map label for this gene is udg [H]

Identifier: 119775371

GI number: 119775371

Start: 2700084

End: 2701442

Strand: Reverse

Name: udg [H]

Synonym: Sama_2236

Alternate gene names: 119775371

Gene position: 2701442-2700084 (Counterclockwise)

Preceding gene: 119775372

Following gene: 119775370

Centisome position: 62.73

GC content: 54.01

Gene sequence:

>1359_bases
ATGAAAGTCACAGTGTTTGGTGTAGGTTACGTTGGTTTGGTACAGGGCGCAGTGCTTGCGGAAGTGGGACACGATGTCTT
GTGTATAGACATAGACGCCGCTAAGATTGAGCGCCTCGATAAAGGTCAGATCCCGATTTATGAGCCAGGTCTCGAAGCCC
TGGTAAAGGAACAAACTGCCCATAAACGTTTGTCATTTTCTACGGATCCCATTGCCGGCGTTGCCCATGGTGAGGTGCTT
TTTATCGCCGTGGGGACGCCCCCTGATGAAGACGGCAGCGCTGACCTGGCCCACGTGCTGGCGGTGGCAAGAGACATTGG
GCTGCACATGTTTGACCCCAAAATTGTGGTCAATAAAAGCACTGTGCCCGTGGGCACGGCCGATAAGGTGAGGGACACCA
TAGCGGCTGAATTGGCCTCACGGGATTTGAATATCTGTGTTGATGTGGTGTCTAACCCTGAGTTTCTCAAAGAAGGGGCT
GCCCTTGATGACTGCCGCCGCCCTGATCGCATTATTGTTGGTAGCGATTCGCAGGACGCCCAGGACGTGATGCGGGAGCT
TTACGCGCCCTTTAACCGCAATCACGACCGCATGATCTTTATGGATGTGCGCAGCGCCGAACTGACCAAGTATGCGGCCA
ACTGCATGCTGGCCACCAAAATTTCTTTCATGAATGAGATGGCGAATATCGCCGAACACCTTGGCGCCGATATTGAAATG
GTGCGTAAGGGGATTGGCTCCGATCCGCGCATCGGTTATCAGTTTATCTACCCCGGCTGTGGTTATGGGGGCTCCTGTTT
CCCGAAAGACGTTAAAGCTCTGGTGAAAACCTCTGAAAAAATTGGTGTTGACGCTCGGGTGCTCAAGTCAGTGGAAGCGG
TTAATCTCAAGCAAAAGCAGCGCTTACCTGAGCTGGTGAAACAACACTTTGGCGATGATTTGTCCGGGCTGGTGTTTGCG
CTCTGGGGCCTGTCGTTTAAACCCCAAACCGATGATATGCGTGAGGCGCCAAGCCGGGTGGTCATCGAAGCGATTATCGC
TGCAGGCGGCACAGTGCAGGCATTTGACCCCGAGGCCATGGCCGAAGCACAGCGCATTTACGGTGTGCGCGACGAGCTTA
AGCTGCTTGGTACCAAGGAAGCGGCGCTAAGTGGCGCCGATGGTCTTATCGTGTGCACCGAGTGGTCGAGTTTCAGGGCG
CCGGACTTTAATGAAATCAAGCGCCTTTTGAAGCAGCCGGTGATTTTTGATGGCCGAAACCTGTACGACCCGGCAAGGCT
TGAGGCCAAAGGCATTGCCTATTACGGTATTGGCCGTGGTCGCTCGGTAAAGCATCCTGATGTGCGCAAGGTACTCTGA

Upstream 100 bases:

>100_bases
GCTGTGCAATACCCGCTGCGCATTTTTTATGCGTTCTGTCATATGCTTGCGACAAAACGTATGGCATGCTTAAACATAAT
GTGGAGAAACGGGGACACCG

Downstream 100 bases:

>100_bases
TGACTTATGGCAGTGTAAGGAGAATTAAGTGAGCCAATCCATGAAAATATTGGTCACAGGCGCCGCCGGATTTATTGGCG
CTGCCGCATGCAAAAGGCTG

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKVTVFGVGYVGLVQGAVLAEVGHDVLCIDIDAAKIERLDKGQIPIYEPGLEALVKEQTAHKRLSFSTDPIAGVAHGEVL
FIAVGTPPDEDGSADLAHVLAVARDIGLHMFDPKIVVNKSTVPVGTADKVRDTIAAELASRDLNICVDVVSNPEFLKEGA
ALDDCRRPDRIIVGSDSQDAQDVMRELYAPFNRNHDRMIFMDVRSAELTKYAANCMLATKISFMNEMANIAEHLGADIEM
VRKGIGSDPRIGYQFIYPGCGYGGSCFPKDVKALVKTSEKIGVDARVLKSVEAVNLKQKQRLPELVKQHFGDDLSGLVFA
LWGLSFKPQTDDMREAPSRVVIEAIIAAGGTVQAFDPEAMAEAQRIYGVRDELKLLGTKEAALSGADGLIVCTEWSSFRA
PDFNEIKRLLKQPVIFDGRNLYDPARLEAKGIAYYGIGRGRSVKHPDVRKVL

Sequences:

>Translated_452_residues
MKVTVFGVGYVGLVQGAVLAEVGHDVLCIDIDAAKIERLDKGQIPIYEPGLEALVKEQTAHKRLSFSTDPIAGVAHGEVL
FIAVGTPPDEDGSADLAHVLAVARDIGLHMFDPKIVVNKSTVPVGTADKVRDTIAAELASRDLNICVDVVSNPEFLKEGA
ALDDCRRPDRIIVGSDSQDAQDVMRELYAPFNRNHDRMIFMDVRSAELTKYAANCMLATKISFMNEMANIAEHLGADIEM
VRKGIGSDPRIGYQFIYPGCGYGGSCFPKDVKALVKTSEKIGVDARVLKSVEAVNLKQKQRLPELVKQHFGDDLSGLVFA
LWGLSFKPQTDDMREAPSRVVIEAIIAAGGTVQAFDPEAMAEAQRIYGVRDELKLLGTKEAALSGADGLIVCTEWSSFRA
PDFNEIKRLLKQPVIFDGRNLYDPARLEAKGIAYYGIGRGRSVKHPDVRKVL
>Mature_452_residues
MKVTVFGVGYVGLVQGAVLAEVGHDVLCIDIDAAKIERLDKGQIPIYEPGLEALVKEQTAHKRLSFSTDPIAGVAHGEVL
FIAVGTPPDEDGSADLAHVLAVARDIGLHMFDPKIVVNKSTVPVGTADKVRDTIAAELASRDLNICVDVVSNPEFLKEGA
ALDDCRRPDRIIVGSDSQDAQDVMRELYAPFNRNHDRMIFMDVRSAELTKYAANCMLATKISFMNEMANIAEHLGADIEM
VRKGIGSDPRIGYQFIYPGCGYGGSCFPKDVKALVKTSEKIGVDARVLKSVEAVNLKQKQRLPELVKQHFGDDLSGLVFA
LWGLSFKPQTDDMREAPSRVVIEAIIAAGGTVQAFDPEAMAEAQRIYGVRDELKLLGTKEAALSGADGLIVCTEWSSFRA
PDFNEIKRLLKQPVIFDGRNLYDPARLEAKGIAYYGIGRGRSVKHPDVRKVL

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=456, Percent_Identity=33.3333333333333, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI296040438, Length=358, Percent_Identity=33.7988826815642, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI296040443, Length=318, Percent_Identity=33.0188679245283, Blast_Score=160, Evalue=3e-39,
Organism=Escherichia coli, GI1788340, Length=360, Percent_Identity=27.5, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI48994968, Length=446, Percent_Identity=26.2331838565022, Blast_Score=130, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17560350, Length=465, Percent_Identity=32.6881720430108, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI17136908, Length=464, Percent_Identity=31.4655172413793, Blast_Score=224, Evalue=6e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49308; Mature: 49308

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTVFGVGYVGLVQGAVLAEVGHDVLCIDIDAAKIERLDKGQIPIYEPGLEALVKEQTA
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCCCCCCCHHHHHHHHHH
HKRLSFSTDPIAGVAHGEVLFIAVGTPPDEDGSADLAHVLAVARDIGLHMFDPKIVVNKS
HHHCCCCCCCCCEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEECCEEEEECC
TVPVGTADKVRDTIAAELASRDLNICVDVVSNPEFLKEGAALDDCRRPDRIIVGSDSQDA
CCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHCCCCHHHCCCCCEEEECCCCCHH
QDVMRELYAPFNRNHDRMIFMDVRSAELTKYAANCMLATKISFMNEMANIAEHLGADIEM
HHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRKGIGSDPRIGYQFIYPGCGYGGSCFPKDVKALVKTSEKIGVDARVLKSVEAVNLKQKQ
HHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHH
RLPELVKQHFGDDLSGLVFALWGLSFKPQTDDMREAPSRVVIEAIIAAGGTVQAFDPEAM
HHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHCHHHHHHHHHHHCCCEEEECCHHHH
AEAQRIYGVRDELKLLGTKEAALSGADGLIVCTEWSSFRAPDFNEIKRLLKQPVIFDGRN
HHHHHHHCCHHHHHHHCCHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCEECCCC
LYDPARLEAKGIAYYGIGRGRSVKHPDVRKVL
CCCCHHCCCCCEEEEECCCCCCCCCCHHHHCC
>Mature Secondary Structure
MKVTVFGVGYVGLVQGAVLAEVGHDVLCIDIDAAKIERLDKGQIPIYEPGLEALVKEQTA
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCCCCCCCHHHHHHHHHH
HKRLSFSTDPIAGVAHGEVLFIAVGTPPDEDGSADLAHVLAVARDIGLHMFDPKIVVNKS
HHHCCCCCCCCCEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEECCEEEEECC
TVPVGTADKVRDTIAAELASRDLNICVDVVSNPEFLKEGAALDDCRRPDRIIVGSDSQDA
CCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHCCCCHHHCCCCCEEEECCCCCHH
QDVMRELYAPFNRNHDRMIFMDVRSAELTKYAANCMLATKISFMNEMANIAEHLGADIEM
HHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRKGIGSDPRIGYQFIYPGCGYGGSCFPKDVKALVKTSEKIGVDARVLKSVEAVNLKQKQ
HHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHH
RLPELVKQHFGDDLSGLVFALWGLSFKPQTDDMREAPSRVVIEAIIAAGGTVQAFDPEAM
HHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHCHHHHHHHHHHHCCCEEEECCHHHH
AEAQRIYGVRDELKLLGTKEAALSGADGLIVCTEWSSFRAPDFNEIKRLLKQPVIFDGRN
HHHHHHHCCHHHHHHHCCHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCEECCCC
LYDPARLEAKGIAYYGIGRGRSVKHPDVRKVL
CCCCHHCCCCCEEEEECCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]