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The map label for this gene is asd [H]

Identifier: 119775287

GI number: 119775287

Start: 2600610

End: 2601626

Strand: Reverse

Name: asd [H]

Synonym: Sama_2152

Alternate gene names: 119775287

Gene position: 2601626-2600610 (Counterclockwise)

Preceding gene: 119775288

Following gene: 119775286

Centisome position: 60.42

GC content: 53.1

Gene sequence:

>1017_bases
ATGTCGCAGGAATTTAATGTCGTAGTTTTGGGTGCATCGGGCGCCGTGGGTCAGACCATGATCGAGATCCTCGAAGAGCG
CAATTTCCCGGTTGCCAAGCTGTTCCCTCTGGCCAGTGCCCGCAGCGCCGGTGATACCGTAAGCTTCCACGGTAAACAGG
TGGAAATTCTTGACGTTGAAACCTTTGATTGGTCACAGGCTCAAATCGGTTTCTTCTCCGCGGGCGGTGATGTGTCTGCT
AAGTGGGCCCCCATCGCGGCAGAGCACGGCTGCGTAGTTATCGACAACACGTCACACTTCCGCTATGACCTGGATATCCC
GCTGGTGGTGCCAGAAGTGAACCCTGAGGCCATTGCCGATTTCCGTAACCGTAATATCATTGCCAACCCCAACTGCTCCA
CCATTCAGATGTTGGTGGCACTGAAGCCCATTTACGATGCCTACGGAATCGATCGCATCAACGTGTGCACCTATCAGTCG
GTGTCCGGTACCGGTAAAAAGGCTATCGAAGAGCTGGCGGGCCAGTGTGCCAAGCTGCTCCAGGGACTGCCAATCGAGCC
AAGCGTTTATCCAAAGCAGATAGCTTTTAACGTGCTGCCACATATCGATAAATTCCAGGATAATGGCTACACCAAAGAAG
AGATGAAAATGGTGTGGGAGACCCGCAAAATTTTCGGTGACGACTCTATTCTGGTGAACCCTACGGCGGTGCGTGTACCT
GTGTTTTACGGTCACTCCGAAGCCGTGCATATCGAAACCCGTGACCCGGTGGATGCCGACACTGTGAAAGCATTGCTGCG
CGATGCCCCCGGTGTCGTGCTTTTTGAAGACGATGATGATTACCCAACCGCCGTTACCGACGGTGCTGGCCAGGATCCTG
TGTTCGTTGGCCGTGTGCGTAACGACATCTCTCATCCCAACGGGATCAACCTTTGGGTGGTGTCAGATAACATTCGCAAA
GGTGCTGCCCTAAACAGCGTACAAATTGGTGAAATTCTCATCCGCGATTATCTGTAA

Upstream 100 bases:

>100_bases
GTCACAGACGCGAATTCAGCGCCCTTAAGCTGGAAAATGCTAAGGGATCTGAGGTAAATTGGTTGTCCTTTTTGGGTTTT
TCTAACGTCGGTTGAGTATT

Downstream 100 bases:

>100_bases
AAATACACCGAAGTCGCTGACTTTGTTGAAAAAGCCCGCAATAAGCGGGCTTTTTTTGTTTTACATTTGTGAACAGTAGC
AGGGCTTGGAATTCTGGTTT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSQEFNVVVLGASGAVGQTMIEILEERNFPVAKLFPLASARSAGDTVSFHGKQVEILDVETFDWSQAQIGFFSAGGDVSA
KWAPIAAEHGCVVIDNTSHFRYDLDIPLVVPEVNPEAIADFRNRNIIANPNCSTIQMLVALKPIYDAYGIDRINVCTYQS
VSGTGKKAIEELAGQCAKLLQGLPIEPSVYPKQIAFNVLPHIDKFQDNGYTKEEMKMVWETRKIFGDDSILVNPTAVRVP
VFYGHSEAVHIETRDPVDADTVKALLRDAPGVVLFEDDDDYPTAVTDGAGQDPVFVGRVRNDISHPNGINLWVVSDNIRK
GAALNSVQIGEILIRDYL

Sequences:

>Translated_338_residues
MSQEFNVVVLGASGAVGQTMIEILEERNFPVAKLFPLASARSAGDTVSFHGKQVEILDVETFDWSQAQIGFFSAGGDVSA
KWAPIAAEHGCVVIDNTSHFRYDLDIPLVVPEVNPEAIADFRNRNIIANPNCSTIQMLVALKPIYDAYGIDRINVCTYQS
VSGTGKKAIEELAGQCAKLLQGLPIEPSVYPKQIAFNVLPHIDKFQDNGYTKEEMKMVWETRKIFGDDSILVNPTAVRVP
VFYGHSEAVHIETRDPVDADTVKALLRDAPGVVLFEDDDDYPTAVTDGAGQDPVFVGRVRNDISHPNGINLWVVSDNIRK
GAALNSVQIGEILIRDYL
>Mature_337_residues
SQEFNVVVLGASGAVGQTMIEILEERNFPVAKLFPLASARSAGDTVSFHGKQVEILDVETFDWSQAQIGFFSAGGDVSAK
WAPIAAEHGCVVIDNTSHFRYDLDIPLVVPEVNPEAIADFRNRNIIANPNCSTIQMLVALKPIYDAYGIDRINVCTYQSV
SGTGKKAIEELAGQCAKLLQGLPIEPSVYPKQIAFNVLPHIDKFQDNGYTKEEMKMVWETRKIFGDDSILVNPTAVRVPV
FYGHSEAVHIETRDPVDADTVKALLRDAPGVVLFEDDDDYPTAVTDGAGQDPVFVGRVRNDISHPNGINLWVVSDNIRKG
AALNSVQIGEILIRDYL

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=339, Percent_Identity=43.952802359882, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1789841, Length=357, Percent_Identity=28.0112044817927, Blast_Score=92, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6320362, Length=385, Percent_Identity=28.8311688311688, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37058; Mature: 36927

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQEFNVVVLGASGAVGQTMIEILEERNFPVAKLFPLASARSAGDTVSFHGKQVEILDVE
CCCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHEEECCCCCCCCCEEEECCCEEEEEEEE
TFDWSQAQIGFFSAGGDVSAKWAPIAAEHGCVVIDNTSHFRYDLDIPLVVPEVNPEAIAD
CCCCCCCEEEEEECCCCCCCEECCEECCCCEEEEECCCCEEEECCCEEEEECCCHHHHHH
FRNRNIIANPNCSTIQMLVALKPIYDAYGIDRINVCTYQSVSGTGKKAIEELAGQCAKLL
HHCCCEEECCCCHHHEEEEHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHH
QGLPIEPSVYPKQIAFNVLPHIDKFQDNGYTKEEMKMVWETRKIFGDDSILVNPTAVRVP
CCCCCCCCCCHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCEEECCCEEEEE
VFYGHSEAVHIETRDPVDADTVKALLRDAPGVVLFEDDDDYPTAVTDGAGQDPVFVGRVR
EEECCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEECCCCCCCCEEEEEHH
NDISHPNGINLWVVSDNIRKGAALNSVQIGEILIRDYL
HCCCCCCCCEEEEEECCCCCCCCCCCEEHHHHHHHHCC
>Mature Secondary Structure 
SQEFNVVVLGASGAVGQTMIEILEERNFPVAKLFPLASARSAGDTVSFHGKQVEILDVE
CCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHEEECCCCCCCCCEEEECCCEEEEEEEE
TFDWSQAQIGFFSAGGDVSAKWAPIAAEHGCVVIDNTSHFRYDLDIPLVVPEVNPEAIAD
CCCCCCCEEEEEECCCCCCCEECCEECCCCEEEEECCCCEEEECCCEEEEECCCHHHHHH
FRNRNIIANPNCSTIQMLVALKPIYDAYGIDRINVCTYQSVSGTGKKAIEELAGQCAKLL
HHCCCEEECCCCHHHEEEEHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHH
QGLPIEPSVYPKQIAFNVLPHIDKFQDNGYTKEEMKMVWETRKIFGDDSILVNPTAVRVP
CCCCCCCCCCHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCEEECCCEEEEE
VFYGHSEAVHIETRDPVDADTVKALLRDAPGVVLFEDDDDYPTAVTDGAGQDPVFVGRVR
EEECCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEECCCCCCCCEEEEEHH
NDISHPNGINLWVVSDNIRKGAALNSVQIGEILIRDYL
HCCCCCCCCEEEEEECCCCCCCCCCCEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163523 [H]