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The map label for this gene is pip [H]

Identifier: 119775278

GI number: 119775278

Start: 2588046

End: 2589365

Strand: Direct

Name: pip [H]

Synonym: Sama_2143

Alternate gene names: 119775278

Gene position: 2588046-2589365 (Clockwise)

Preceding gene: 119775274

Following gene: 119775279

Centisome position: 60.1

GC content: 54.17

Gene sequence:

>1320_bases
ATGTCTGTTTCAAGCAAACACCCCAATGCCACAGGGTCAAAATCCACCCTTCCACAAATGATTGCGGAAAAGCTGACCTT
TACCCTGCCCCTGGATTATCAGGACGCAGCAAAAGGAGAGATTAACGTCTTCGCCCGTACTTTGGTACACAAGGACAAGC
AACATTTGGAATTGCCCTGGCTGGTGTATTTCCAGGGAGGCCCCGGCTTTGCCGCCCAGCGCCCGGTCAGTCACAGTGGC
TGGATAAAGCGGGCGCTGACAGAGTATCGGGTACTGCTGCTTGATCAGCGCGGCACAGGGCTTTCAACCCCAGTAAACGC
CACAAGCCTTGCACACCTGGATGATGCAGGGAAAGCCGACTATCTCAGTCACTTCCGCGCCGATAACATTATCAGAGACG
CCGAAGCCATTCGCGCCATTTTAAGCCCCGACACCCCCTGGACCATTCTGGGCCAAAGTTTTGGCGGCTTTTGTGTACTC
AGGTACTTGAGTGTTGCCGCCCATGGCTTGAAAGAAGCCTTTATCACGGGCGGTATCCCTCCCCTTGGGCGCAGTGCAGA
CGAAGTTTACCGGGCAACCTATAAACGGGTATTGCAGAAGAATCGTGACTTCCATCAACGCTTCACGGATGCGGCCCCAC
TGCTTGCTGATTTGCACCGCTACCTGCTTGAGCACCCTGTGTTATTACCACCTGGACAGCAATTAACACCGCAGATGTTG
CAGCTGCTGGGAATACATCTGGGGATGGAAGATGGCCCAGAGAGCGTCTATTACCTGCTTGAGCAGGCATTGCAGTTCAC
GCCCTCCGGGAACCGCATCAACCCACTTTTCGTAGAGCGCTTCGCTCAAATGCTGGATTACAACACCAATCCACTCTTTG
CCGTGCTCCATGAGGCCATTTACTGCGAGCAGCAGGCGTCCAATTGGGCGGCGCACCGTATTCGCGCTGAATATCCGCAG
TTTGACGCCGCGCCCCCTGCACCTTTGCTGCTCACGGGCGAGATGATTTTCCCCTGGATGTTTGACTGCTTTGAACACCT
CAAACCACTGAAAGGATGCGCGGAGTTACTCGCGGCGAAAACAGATTGGCCACCGCTCTATGACCCAGCGGCGCTCGCCA
ACAATACCGTGCCGGTTGCTGCCGCTATTTACAGTGAAGATATGTTTGTGGAAATGGACTTCAGCCTGGAAACAGCCAAG
CAGGTGGCCAATCTCAAGTATTGGCTGACGTCCGAGTATGAACATAATGGCATTCGTATGGATGGTGAACGCATATTCGA
TCGCCTCATCGCCATCAATCGCGGCGCCTGTTTACGCTAG

Upstream 100 bases:

>100_bases
AGAAATTGATCTTGATAGGGCTTTGGCAAGATTGATGACTTGCCAGATAGAGGCATTTGTATACAATCCGCAACAAGATG
CCAGCCAAAGAGTCCTGCCC

Downstream 100 bases:

>100_bases
TCAATAGGCGCTCAGGTGATTTTAAGAAAGGCTTAAGCCCGAGTTGGCACACTCATATAGGTTCCTCCTCTATGAGCGTT
TGTGTTAACCGCTTTTGGTT

Product: alpha/beta hydrolase fold domain-containing protein

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MSVSSKHPNATGSKSTLPQMIAEKLTFTLPLDYQDAAKGEINVFARTLVHKDKQHLELPWLVYFQGGPGFAAQRPVSHSG
WIKRALTEYRVLLLDQRGTGLSTPVNATSLAHLDDAGKADYLSHFRADNIIRDAEAIRAILSPDTPWTILGQSFGGFCVL
RYLSVAAHGLKEAFITGGIPPLGRSADEVYRATYKRVLQKNRDFHQRFTDAAPLLADLHRYLLEHPVLLPPGQQLTPQML
QLLGIHLGMEDGPESVYYLLEQALQFTPSGNRINPLFVERFAQMLDYNTNPLFAVLHEAIYCEQQASNWAAHRIRAEYPQ
FDAAPPAPLLLTGEMIFPWMFDCFEHLKPLKGCAELLAAKTDWPPLYDPAALANNTVPVAAAIYSEDMFVEMDFSLETAK
QVANLKYWLTSEYEHNGIRMDGERIFDRLIAINRGACLR

Sequences:

>Translated_439_residues
MSVSSKHPNATGSKSTLPQMIAEKLTFTLPLDYQDAAKGEINVFARTLVHKDKQHLELPWLVYFQGGPGFAAQRPVSHSG
WIKRALTEYRVLLLDQRGTGLSTPVNATSLAHLDDAGKADYLSHFRADNIIRDAEAIRAILSPDTPWTILGQSFGGFCVL
RYLSVAAHGLKEAFITGGIPPLGRSADEVYRATYKRVLQKNRDFHQRFTDAAPLLADLHRYLLEHPVLLPPGQQLTPQML
QLLGIHLGMEDGPESVYYLLEQALQFTPSGNRINPLFVERFAQMLDYNTNPLFAVLHEAIYCEQQASNWAAHRIRAEYPQ
FDAAPPAPLLLTGEMIFPWMFDCFEHLKPLKGCAELLAAKTDWPPLYDPAALANNTVPVAAAIYSEDMFVEMDFSLETAK
QVANLKYWLTSEYEHNGIRMDGERIFDRLIAINRGACLR
>Mature_438_residues
SVSSKHPNATGSKSTLPQMIAEKLTFTLPLDYQDAAKGEINVFARTLVHKDKQHLELPWLVYFQGGPGFAAQRPVSHSGW
IKRALTEYRVLLLDQRGTGLSTPVNATSLAHLDDAGKADYLSHFRADNIIRDAEAIRAILSPDTPWTILGQSFGGFCVLR
YLSVAAHGLKEAFITGGIPPLGRSADEVYRATYKRVLQKNRDFHQRFTDAAPLLADLHRYLLEHPVLLPPGQQLTPQMLQ
LLGIHLGMEDGPESVYYLLEQALQFTPSGNRINPLFVERFAQMLDYNTNPLFAVLHEAIYCEQQASNWAAHRIRAEYPQF
DAAPPAPLLLTGEMIFPWMFDCFEHLKPLKGCAELLAAKTDWPPLYDPAALANNTVPVAAAIYSEDMFVEMDFSLETAKQ
VANLKYWLTSEYEHNGIRMDGERIFDRLIAINRGACLR

Specific function: Higher activity toward long peptides. Acts on hydroxyproline beta-naphthylamide with almost as high an activity as on proline beta-naphthylamide [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 49264; Mature: 49133

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSSKHPNATGSKSTLPQMIAEKLTFTLPLDYQDAAKGEINVFARTLVHKDKQHLELPW
CCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHCCHHHCCCCE
LVYFQGGPGFAAQRPVSHSGWIKRALTEYRVLLLDQRGTGLSTPVNATSLAHLDDAGKAD
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHCCCCCCHH
YLSHFRADNIIRDAEAIRAILSPDTPWTILGQSFGGFCVLRYLSVAAHGLKEAFITGGIP
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
PLGRSADEVYRATYKRVLQKNRDFHQRFTDAAPLLADLHRYLLEHPVLLPPGQQLTPQML
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
QLLGIHLGMEDGPESVYYLLEQALQFTPSGNRINPLFVERFAQMLDYNTNPLFAVLHEAI
HHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
YCEQQASNWAAHRIRAEYPQFDAAPPAPLLLTGEMIFPWMFDCFEHLKPLKGCAELLAAK
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCC
TDWPPLYDPAALANNTVPVAAAIYSEDMFVEMDFSLETAKQVANLKYWLTSEYEHNGIRM
CCCCCCCCCHHHCCCCCCEEHEEECCCEEEEECCCHHHHHHHHHHHHEEECCCCCCCEEE
DGERIFDRLIAINRGACLR
CHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SVSSKHPNATGSKSTLPQMIAEKLTFTLPLDYQDAAKGEINVFARTLVHKDKQHLELPW
CCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHCCHHHCCCCE
LVYFQGGPGFAAQRPVSHSGWIKRALTEYRVLLLDQRGTGLSTPVNATSLAHLDDAGKAD
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHCCCCCCHH
YLSHFRADNIIRDAEAIRAILSPDTPWTILGQSFGGFCVLRYLSVAAHGLKEAFITGGIP
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
PLGRSADEVYRATYKRVLQKNRDFHQRFTDAAPLLADLHRYLLEHPVLLPPGQQLTPQML
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
QLLGIHLGMEDGPESVYYLLEQALQFTPSGNRINPLFVERFAQMLDYNTNPLFAVLHEAI
HHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
YCEQQASNWAAHRIRAEYPQFDAAPPAPLLLTGEMIFPWMFDCFEHLKPLKGCAELLAAK
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCC
TDWPPLYDPAALANNTVPVAAAIYSEDMFVEMDFSLETAKQVANLKYWLTSEYEHNGIRM
CCCCCCCCCHHHCCCCCCEEHEEECCCEEEEECCCHHHHHHHHHHHHEEECCCCCCCEEE
DGERIFDRLIAINRGACLR
CHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883756 [H]