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The map label for this gene is pabC [H]

Identifier: 119775180

GI number: 119775180

Start: 2481493

End: 2482383

Strand: Reverse

Name: pabC [H]

Synonym: Sama_2045

Alternate gene names: 119775180

Gene position: 2482383-2481493 (Counterclockwise)

Preceding gene: 119775181

Following gene: 119775179

Centisome position: 57.65

GC content: 54.99

Gene sequence:

>891_bases
ATGGCCATCTTGACCATGGAAAGCGGTAAGGGCAAGGCGACTGCCAGGCTCAACTGGCTCGATTTAACCCTGGAGTCTAC
TGAGTCCGCACATGCTCAGAGCATTTCCCCAATGGACAGAGGCCTCGCCTATGGCGATGGCCTTTTTGCCACCATGGCGC
TGACACCCACAGGGGACGTCGCTTTTCTCGATACCCACTTATCTCGCTTACACCAGGGCGCGTGCCGTCTGGGCTTTGTG
CTGGATCTCAAGGATATAAAGAGTAGGCTCGTGCTGGCCGCGAAGGCCCAAGCTAACCAGCAAACCCCGAGAGGCCTGAA
GCTCCTTATCAGCCGCGGACCCGGTGGCCGCGGCTATCAGGCACCCGATGACGCGAGCCCCATAGCCGTACTGAGCGCCT
TTGATGTTCCGGCCCATTACCGCGAGTGGCAACGTAAAGGCATTTGCCTCTTCTCCAGTGAACTGCAGCTGGCCAAACAG
CCAAAGCTTGCGGGAATGAAACATCTTAATCGTCTTGAGCAGGTGCTTATTCGCACTCAGCAGATGCCGGACTGGGCACA
GGATTTTCTGGTGTCAGACACGGATGGCGCCCTGATAGAAGCGTCCATGGCCAACCTGATTTTTATCACAGGTGGTACCG
CATACACGCCTTATCATGCCTTTGCCGGTGTCTCGGGCGTGATGCGCGAGCAGATAATTCACGCCTTGCTGGAACGAGGC
TACAGGGTGGTGGCCGATAAGCTTGACCCAGATATGTTGGTAAAGGCGCAGGCTGTCATCATGTGCAACAGTTTGCTTGG
GCTGGTGGATGTGGTGCGTATCGATAACTTTCATTATCAGGTTTTTACTGAAAGCCAGAGCATTCGCGATGCGCTGGAAT
TGAATTTATGA

Upstream 100 bases:

>100_bases
GCCCCGTGTCCCGCCCCTATAACAAGCGTAAAAACGCCAAGTACAAGGATCAGCAGGAAGCGGTGGCCAGCCGCATCAGC
CAGGACTCCTGAGTCTGCCC

Downstream 100 bases:

>100_bases
AGAGAATTCTCATTGGGATAGTTGGGGCGATTATGTCCCTGACTTTGCTCGGCGCCGCTACGGCGTTATGGGGTATGAAA
GAGCTTGAAACCTTTGCCAA

Product: aminodeoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MAILTMESGKGKATARLNWLDLTLESTESAHAQSISPMDRGLAYGDGLFATMALTPTGDVAFLDTHLSRLHQGACRLGFV
LDLKDIKSRLVLAAKAQANQQTPRGLKLLISRGPGGRGYQAPDDASPIAVLSAFDVPAHYREWQRKGICLFSSELQLAKQ
PKLAGMKHLNRLEQVLIRTQQMPDWAQDFLVSDTDGALIEASMANLIFITGGTAYTPYHAFAGVSGVMREQIIHALLERG
YRVVADKLDPDMLVKAQAVIMCNSLLGLVDVVRIDNFHYQVFTESQSIRDALELNL

Sequences:

>Translated_296_residues
MAILTMESGKGKATARLNWLDLTLESTESAHAQSISPMDRGLAYGDGLFATMALTPTGDVAFLDTHLSRLHQGACRLGFV
LDLKDIKSRLVLAAKAQANQQTPRGLKLLISRGPGGRGYQAPDDASPIAVLSAFDVPAHYREWQRKGICLFSSELQLAKQ
PKLAGMKHLNRLEQVLIRTQQMPDWAQDFLVSDTDGALIEASMANLIFITGGTAYTPYHAFAGVSGVMREQIIHALLERG
YRVVADKLDPDMLVKAQAVIMCNSLLGLVDVVRIDNFHYQVFTESQSIRDALELNL
>Mature_295_residues
AILTMESGKGKATARLNWLDLTLESTESAHAQSISPMDRGLAYGDGLFATMALTPTGDVAFLDTHLSRLHQGACRLGFVL
DLKDIKSRLVLAAKAQANQQTPRGLKLLISRGPGGRGYQAPDDASPIAVLSAFDVPAHYREWQRKGICLFSSELQLAKQP
KLAGMKHLNRLEQVLIRTQQMPDWAQDFLVSDTDGALIEASMANLIFITGGTAYTPYHAFAGVSGVMREQIIHALLERGY
RVVADKLDPDMLVKAQAVIMCNSLLGLVDVVRIDNFHYQVFTESQSIRDALELNL

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=251, Percent_Identity=35.4581673306773, Blast_Score=145, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 32464; Mature: 32333

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILTMESGKGKATARLNWLDLTLESTESAHAQSISPMDRGLAYGDGLFATMALTPTGDV
CEEEEEECCCCCEEEEEEEEEEEEECCCCHHHHCCCHHHHCCCCCCCEEEEEEECCCCCC
AFLDTHLSRLHQGACRLGFVLDLKDIKSRLVLAAKAQANQQTPRGLKLLISRGPGGRGYQ
HHHHHHHHHHHHCHHHEEEEEEHHHHHHHHEEEEHHHCCCCCCCCEEEEEECCCCCCCCC
APDDASPIAVLSAFDVPAHYREWQRKGICLFSSELQLAKQPKLAGMKHLNRLEQVLIRTQ
CCCCCCCEEEEEECCCCHHHHHHHHCCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHH
QMPDWAQDFLVSDTDGALIEASMANLIFITGGTAYTPYHAFAGVSGVMREQIIHALLERG
CCCCHHHHHEECCCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
YRVVADKLDPDMLVKAQAVIMCNSLLGLVDVVRIDNFHYQVFTESQSIRDALELNL
CEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCC
>Mature Secondary Structure 
AILTMESGKGKATARLNWLDLTLESTESAHAQSISPMDRGLAYGDGLFATMALTPTGDV
EEEEEECCCCCEEEEEEEEEEEEECCCCHHHHCCCHHHHCCCCCCCEEEEEEECCCCCC
AFLDTHLSRLHQGACRLGFVLDLKDIKSRLVLAAKAQANQQTPRGLKLLISRGPGGRGYQ
HHHHHHHHHHHHCHHHEEEEEEHHHHHHHHEEEEHHHCCCCCCCCEEEEEECCCCCCCCC
APDDASPIAVLSAFDVPAHYREWQRKGICLFSSELQLAKQPKLAGMKHLNRLEQVLIRTQ
CCCCCCCEEEEEECCCCHHHHHHHHCCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHH
QMPDWAQDFLVSDTDGALIEASMANLIFITGGTAYTPYHAFAGVSGVMREQIIHALLERG
CCCCHHHHHEECCCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
YRVVADKLDPDMLVKAQAVIMCNSLLGLVDVVRIDNFHYQVFTESQSIRDALELNL
CEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]