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The map label for this gene is dcd

Identifier: 119775181

GI number: 119775181

Start: 2482392

End: 2482976

Strand: Reverse

Name: dcd

Synonym: Sama_2046

Alternate gene names: 119775181

Gene position: 2482976-2482392 (Counterclockwise)

Preceding gene: 119775182

Following gene: 119775180

Centisome position: 57.66

GC content: 56.92

Gene sequence:

>585_bases
ATGCGATTGACAGACTTTGAAATTGAGCAGGCCCTCGACGCCGGAACCATCCTTATTGAGCCTCGGCCAAGCAATGATGC
TATCAGCGGCGTCAGTGTGGATGTGCGCCTGGGGAACCAATTTCGGGTATTTCAGGATCACACGGCACCCTTTATCGATC
TGAGCGGACCCAGTGCCGAGGTGCAGGCGGCGCTGGACCGGGTCATGAGCGACAAGATTGATATCAAAGACGGCAATGCT
TTTTTCCTACACCCGGGGGAACTGGCGCTTGCCGTGACCCTGGAAAGTGTGACTCTGCCGGCGGATATCGTGGGTTGGCT
CGATGGCCGTTCATCCCTGGCTCGCTTAGGTTTGATGGTCCACGTAACTGCCCACCGTATCGACCCGGGCTGGCAGGGTA
AAATCGTGCTCGAATTCTACAACAGTGGTAAGTTGCCGCTGGCGCTGCGACCTGGCATGACCATAGGTGCGCTTAACTTT
GAACGTTTGAGCGGCCCCGTGTCCCGCCCCTATAACAAGCGTAAAAACGCCAAGTACAAGGATCAGCAGGAAGCGGTGGC
CAGCCGCATCAGCCAGGACTCCTGA

Upstream 100 bases:

>100_bases
CCGTGGTGGTAAAAACCGTATTGCCACTGATATCCTCAAGGCACGTATTCAGCACCTGTTGGCAAAATAAAAACATAAAA
CTCAGGGAGATAAAGGCAAG

Downstream 100 bases:

>100_bases
GTCTGCCCATGGCCATCTTGACCATGGAAAGCGGTAAGGGCAAGGCGACTGCCAGGCTCAACTGGCTCGATTTAACCCTG
GAGTCTACTGAGTCCGCACA

Product: deoxycytidine triphosphate deaminase

Products: NA

Alternate protein names: dCTP deaminase

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MRLTDFEIEQALDAGTILIEPRPSNDAISGVSVDVRLGNQFRVFQDHTAPFIDLSGPSAEVQAALDRVMSDKIDIKDGNA
FFLHPGELALAVTLESVTLPADIVGWLDGRSSLARLGLMVHVTAHRIDPGWQGKIVLEFYNSGKLPLALRPGMTIGALNF
ERLSGPVSRPYNKRKNAKYKDQQEAVASRISQDS

Sequences:

>Translated_194_residues
MRLTDFEIEQALDAGTILIEPRPSNDAISGVSVDVRLGNQFRVFQDHTAPFIDLSGPSAEVQAALDRVMSDKIDIKDGNA
FFLHPGELALAVTLESVTLPADIVGWLDGRSSLARLGLMVHVTAHRIDPGWQGKIVLEFYNSGKLPLALRPGMTIGALNF
ERLSGPVSRPYNKRKNAKYKDQQEAVASRISQDS
>Mature_194_residues
MRLTDFEIEQALDAGTILIEPRPSNDAISGVSVDVRLGNQFRVFQDHTAPFIDLSGPSAEVQAALDRVMSDKIDIKDGNA
FFLHPGELALAVTLESVTLPADIVGWLDGRSSLARLGLMVHVTAHRIDPGWQGKIVLEFYNSGKLPLALRPGMTIGALNF
ERLSGPVSRPYNKRKNAKYKDQQEAVASRISQDS

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family

Homologues:

Organism=Escherichia coli, GI1788379, Length=193, Percent_Identity=75.1295336787565, Blast_Score=297, Evalue=3e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCD_SHEAM (A1S795)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927921.1
- ProteinModelPortal:   A1S795
- SMR:   A1S795
- STRING:   A1S795
- GeneID:   4604296
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_2046
- NMPDR:   fig|326297.7.peg.1921
- eggNOG:   COG0717
- HOGENOM:   HBG553199
- OMA:   FSGHVTL
- PhylomeDB:   A1S795
- ProtClustDB:   PRK00416
- HAMAP:   MF_00146
- InterPro:   IPR011962
- InterPro:   IPR010550
- TIGRFAMs:   TIGR02274

Pfam domain/function: PF06559 DCD

EC number: =3.5.4.13

Molecular weight: Translated: 21238; Mature: 21238

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTDFEIEQALDAGTILIEPRPSNDAISGVSVDVRLGNQFRVFQDHTAPFIDLSGPSAE
CCCCCHHHHHHCCCCEEEECCCCCCCCCCCEEEEEEECCEEEEEECCCCCEEEECCCCHH
VQAALDRVMSDKIDIKDGNAFFLHPGELALAVTLESVTLPADIVGWLDGRSSLARLGLMV
HHHHHHHHHHCCEEECCCCEEEEECCCEEEEEEEECEECCHHHHHHCCCHHHHHHHCEEE
HVTAHRIDPGWQGKIVLEFYNSGKLPLALRPGMTIGALNFERLSGPVSRPYNKRKNAKYK
EEEEEECCCCCCCEEEEEEECCCCEEEEECCCCEEECCCHHHHCCCCCCCCCCCCCCCCC
DQQEAVASRISQDS
HHHHHHHHHHCCCC
>Mature Secondary Structure
MRLTDFEIEQALDAGTILIEPRPSNDAISGVSVDVRLGNQFRVFQDHTAPFIDLSGPSAE
CCCCCHHHHHHCCCCEEEECCCCCCCCCCCEEEEEEECCEEEEEECCCCCEEEECCCCHH
VQAALDRVMSDKIDIKDGNAFFLHPGELALAVTLESVTLPADIVGWLDGRSSLARLGLMV
HHHHHHHHHHCCEEECCCCEEEEECCCEEEEEEEECEECCHHHHHHCCCHHHHHHHCEEE
HVTAHRIDPGWQGKIVLEFYNSGKLPLALRPGMTIGALNFERLSGPVSRPYNKRKNAKYK
EEEEEECCCCCCCEEEEEEECCCCEEEEECCCCEEECCCHHHHCCCCCCCCCCCCCCCCC
DQQEAVASRISQDS
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA