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The map label for this gene is cdd

Identifier: 119775109

GI number: 119775109

Start: 2402667

End: 2403557

Strand: Direct

Name: cdd

Synonym: Sama_1974

Alternate gene names: 119775109

Gene position: 2402667-2403557 (Clockwise)

Preceding gene: 119775108

Following gene: 119775121

Centisome position: 55.8

GC content: 54.43

Gene sequence:

>891_bases
ATGCAAGACAGATTTGTCCGCCGGATAAACGAGCTGCCAAAAGCATTGGCAGATGAACTGCTTCCCATGCTGGGTGAGCA
ATTTTGTGGTCATTTGGATGCGCAGCAGGTAAAGCAGCTCTGCGCAGTGTCAGCAATGGATAGCCACGAGCTGGGATTGG
CACTGCTGCCCATCGCAGCTGCACTGGCTAAGCCTCCAGTAAGTAACTTTTATGTGGGTGCCATTGCCGTGGGAAGCGGC
GGCGACTTTTACATGGGAGCCAATCTGGAGCTGCAGGGTGAAGCCTTGTTTCACTCGGTCCATGCCGAGCAAAGTGCCAT
CAGCCACGCCTGGCTAAGTGGTGAAACACAAATCAGCGATATCATAGTCAACGCCAGCCCCTGCGGTCATTGCCGCCAGT
TTATGAACGAGCTGGTGCAGGGTCAGGCTATTCGTATTCACCTGCCGGGGCAAGACACTGCGCCACTGAGCCACTATCTG
CCCTATGCCTTCGGTCCTGCCGATTTAAATGTTACAGCGCCTCTGCTATCAAAACAGCAAACGGAACTGGTACTGGAAAG
TGATGATCCCTTGCTGATTGAAGCACTCGATCACGCCGGTTTGTCCTACGCCCCATACAGCCAGTGTCACGCCGCGGTGG
TGCTGGAAACTGAAGACGGCGCTAGTTTCTGCGGCCGCTATGCCGAAAACGCCGCCTTTAATCCATCGATGTTGCCCATG
CAGATGGCATTGTCGGCTCTTGTCAGACACAACCGCAGCTTCAGTGACATCAAACGTGCAGTGTTGCTTGAGTCATCACA
GGGTAAAATTTCCCTGGTTGGTGCCACCATGGACGCCCTCCATGCCGTTGCCGTGGTTGAGCTCGAGCATCTGGTCGTTG
ACCCTGTGTAA

Upstream 100 bases:

>100_bases
TAGCAGAAAACCCACATAAAATGGGATTAGACTCCCATTATCTGTGTAACAGAATAACTAAACTGCAAGTCAGTAAAATT
AACAGCGAAGGAAAACGGCT

Downstream 100 bases:

>100_bases
ACCCAAAGCTAATGCAGTAAAAAGCCCGCTTCATGCGGGCTTTTTGTTTTATCGGGAACGGCTCTACCACCGAACTAGCT
GACGATTGATTTAACCAGGA

Product: cytidine deaminase

Products: NA

Alternate protein names: Cytidine aminohydrolase; CDA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MQDRFVRRINELPKALADELLPMLGEQFCGHLDAQQVKQLCAVSAMDSHELGLALLPIAAALAKPPVSNFYVGAIAVGSG
GDFYMGANLELQGEALFHSVHAEQSAISHAWLSGETQISDIIVNASPCGHCRQFMNELVQGQAIRIHLPGQDTAPLSHYL
PYAFGPADLNVTAPLLSKQQTELVLESDDPLLIEALDHAGLSYAPYSQCHAAVVLETEDGASFCGRYAENAAFNPSMLPM
QMALSALVRHNRSFSDIKRAVLLESSQGKISLVGATMDALHAVAVVELEHLVVDPV

Sequences:

>Translated_296_residues
MQDRFVRRINELPKALADELLPMLGEQFCGHLDAQQVKQLCAVSAMDSHELGLALLPIAAALAKPPVSNFYVGAIAVGSG
GDFYMGANLELQGEALFHSVHAEQSAISHAWLSGETQISDIIVNASPCGHCRQFMNELVQGQAIRIHLPGQDTAPLSHYL
PYAFGPADLNVTAPLLSKQQTELVLESDDPLLIEALDHAGLSYAPYSQCHAAVVLETEDGASFCGRYAENAAFNPSMLPM
QMALSALVRHNRSFSDIKRAVLLESSQGKISLVGATMDALHAVAVVELEHLVVDPV
>Mature_296_residues
MQDRFVRRINELPKALADELLPMLGEQFCGHLDAQQVKQLCAVSAMDSHELGLALLPIAAALAKPPVSNFYVGAIAVGSG
GDFYMGANLELQGEALFHSVHAEQSAISHAWLSGETQISDIIVNASPCGHCRQFMNELVQGQAIRIHLPGQDTAPLSHYL
PYAFGPADLNVTAPLLSKQQTELVLESDDPLLIEALDHAGLSYAPYSQCHAAVVLETEDGASFCGRYAENAAFNPSMLPM
QMALSALVRHNRSFSDIKRAVLLESSQGKISLVGATMDALHAVAVVELEHLVVDPV

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family

Homologues:

Organism=Escherichia coli, GI1788465, Length=294, Percent_Identity=44.5578231292517, Blast_Score=211, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDD_SHEAM (A1S723)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927849.1
- ProteinModelPortal:   A1S723
- SMR:   A1S723
- STRING:   A1S723
- GeneID:   4604224
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1974
- NMPDR:   fig|326297.7.peg.1855
- eggNOG:   COG0295
- HOGENOM:   HBG591160
- OMA:   NRSHAPY
- PhylomeDB:   A1S723
- ProtClustDB:   PRK09027
- HAMAP:   MF_01558
- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013171
- InterPro:   IPR006263
- InterPro:   IPR016193
- InterPro:   IPR020797
- PIRSF:   PIRSF006334

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF08211 dCMP_cyt_deam_2; SSF53927 Cytidine_deaminase-like

EC number: =3.5.4.5

Molecular weight: Translated: 31803; Mature: 31803

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: ACT_SITE 103-103

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDRFVRRINELPKALADELLPMLGEQFCGHLDAQQVKQLCAVSAMDSHELGLALLPIAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHH
ALAKPPVSNFYVGAIAVGSGGDFYMGANLELQGEALFHSVHAEQSAISHAWLSGETQISD
HHHCCCCCCEEEEEEEECCCCCEEEECCEEECHHHHHHHHHHHHHHHHHHHCCCCCEEEE
IIVNASPCGHCRQFMNELVQGQAIRIHLPGQDTAPLSHYLPYAFGPADLNVTAPLLSKQQ
EEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCCEECCCCCCEECHHHCCCC
TELVLESDDPLLIEALDHAGLSYAPYSQCHAAVVLETEDGASFCGRYAENAAFNPSMLPM
CEEEEECCCCEEEEEHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCHH
QMALSALVRHNRSFSDIKRAVLLESSQGKISLVGATMDALHAVAVVELEHLVVDPV
HHHHHHHHHCCCCHHHHHHHHHEECCCCEEEEEECHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQDRFVRRINELPKALADELLPMLGEQFCGHLDAQQVKQLCAVSAMDSHELGLALLPIAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHH
ALAKPPVSNFYVGAIAVGSGGDFYMGANLELQGEALFHSVHAEQSAISHAWLSGETQISD
HHHCCCCCCEEEEEEEECCCCCEEEECCEEECHHHHHHHHHHHHHHHHHHHCCCCCEEEE
IIVNASPCGHCRQFMNELVQGQAIRIHLPGQDTAPLSHYLPYAFGPADLNVTAPLLSKQQ
EEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCCEECCCCCCEECHHHCCCC
TELVLESDDPLLIEALDHAGLSYAPYSQCHAAVVLETEDGASFCGRYAENAAFNPSMLPM
CEEEEECCCCEEEEEHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCHH
QMALSALVRHNRSFSDIKRAVLLESSQGKISLVGATMDALHAVAVVELEHLVVDPV
HHHHHHHHHCCCCHHHHHHHHHEECCCCEEEEEECHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA