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The map label for this gene is fadR

Identifier: 119775059

GI number: 119775059

Start: 2352404

End: 2353126

Strand: Reverse

Name: fadR

Synonym: Sama_1924

Alternate gene names: 119775059

Gene position: 2353126-2352404 (Counterclockwise)

Preceding gene: 119775062

Following gene: 119775054

Centisome position: 54.65

GC content: 48.96

Gene sequence:

>723_bases
ATGATAATCAATGCCAAAGGTCCTGCGAGTTTCGCAGAGAAATACATAGTGCGTTCCATTTGGGAAAATAAATTTCCCCC
TGGCTCCATTCTTCCTGCCGAGCGTGAGCTTTCAGAGCTTATCGGTGTAACCCGTACCACATTGAGGGAAGTGTTGCAGC
GTTTGGCCCGCGATGGCTGGCTCACTATCCAGCACGGTAAGCCAACCCGGGTAAATAATTTCTGGGAAACGTCAGGCCTG
AATATTTTGGAAACCATTGCGGACTTGAATCCTGAGGGGTTTCCGGTGTTGGTTGACCAGTTGTTATCGGCCCGAACGAA
TGTCAGCGCTATCTATTTCCGTGGCGCACTGCGTCACAATCCAGAAACCGCAGTAGAAATCCTTGCCCGTATCCATGGTA
TGGAAGATTCGGCTGAAGCATATGCTGAGTTCGATTACGATTTGCATCACACGCTAGCCTTTTCATCGGGTAACCCGCTT
TATGTGTTAATCCTGAACGGTTTTAAAGGACTTTACAGTCGGGTAGGCCGCTATTACTTCTCCAGCGCTGAAGCACGAAA
GTTGGCGATGGATTTTTATATTGAGCTGGAAAAGCTGGCAAAGCGTCATGCGTACGGGGAAGTACCGGCGCTGATGCGAA
GCTATGGCATTAACAGCGGCAAAATGTGGCAAAAGCTGAAAGACGCCATGCCCGCTGATATTAATCAGGATCCACACGGT
TAA

Upstream 100 bases:

>100_bases
CAATTCAAATTGTTCAATAGCACGCTTTAGGTTTTCATTTTTTACCGCTCTGGTATGATCAGTGCCCAACACGAGGTTAA
ACCACTGGAAATTGGGGCTG

Downstream 100 bases:

>100_bases
TGCTTTCAGCGGCATAAAAAACGCAGCCATCAGGCTGCGTTTTTTTATATTTTCACCGAGTGTCCCTCTTCATCTCGTGG
GGGGCAGCGTGCCAGCTCCT

Product: fatty acid metabolism regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTRVNNFWETSGL
NILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRHNPETAVEILARIHGMEDSAEAYAEFDYDLHHTLAFSSGNPL
YVLILNGFKGLYSRVGRYYFSSAEARKLAMDFYIELEKLAKRHAYGEVPALMRSYGINSGKMWQKLKDAMPADINQDPHG

Sequences:

>Translated_240_residues
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTRVNNFWETSGL
NILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRHNPETAVEILARIHGMEDSAEAYAEFDYDLHHTLAFSSGNPL
YVLILNGFKGLYSRVGRYYFSSAEARKLAMDFYIELEKLAKRHAYGEVPALMRSYGINSGKMWQKLKDAMPADINQDPHG
>Mature_240_residues
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTRVNNFWETSGL
NILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRHNPETAVEILARIHGMEDSAEAYAEFDYDLHHTLAFSSGNPL
YVLILNGFKGLYSRVGRYYFSSAEARKLAMDFYIELEKLAKRHAYGEVPALMRSYGINSGKMWQKLKDAMPADINQDPHG

Specific function: Multifunctional regulator of fatty acid metabolism

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1787436, Length=234, Percent_Identity=61.1111111111111, Blast_Score=308, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FADR_SHEAM (A1S6X3)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927799.1
- ProteinModelPortal:   A1S6X3
- SMR:   A1S6X3
- STRING:   A1S6X3
- GeneID:   4604174
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1924
- NMPDR:   fig|326297.7.peg.1809
- eggNOG:   COG2186
- HOGENOM:   HBG296777
- OMA:   IVRSIWE
- PhylomeDB:   A1S6X3
- ProtClustDB:   PRK04984
- GO:   GO:0005737
- HAMAP:   MF_00696
- InterPro:   IPR014178
- InterPro:   IPR008920
- InterPro:   IPR000524
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00035
- SMART:   SM00345
- TIGRFAMs:   TIGR02812

Pfam domain/function: PF07840 FadR_C; PF00392 GntR; SSF48008 FadR_C

EC number: NA

Molecular weight: Translated: 27101; Mature: 27101

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGW
CEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LTIQHGKPTRVNNFWETSGLNILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRHN
EEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHEEEHHHHCC
PETAVEILARIHGMEDSAEAYAEFDYDLHHTLAFSSGNPLYVLILNGFKGLYSRVGRYYF
HHHHHHHHHHHHCCCHHHHHHHHCCCCHHHEEEECCCCCEEEEEECCHHHHHHHHHHHHH
SSAEARKLAMDFYIELEKLAKRHAYGEVPALMRSYGINSGKMWQKLKDAMPADINQDPHG
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGW
CEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LTIQHGKPTRVNNFWETSGLNILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRHN
EEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHEEEHHHHCC
PETAVEILARIHGMEDSAEAYAEFDYDLHHTLAFSSGNPLYVLILNGFKGLYSRVGRYYF
HHHHHHHHHHHHCCCHHHHHHHHCCCCHHHEEEECCCCCEEEEEECCHHHHHHHHHHHHH
SSAEARKLAMDFYIELEKLAKRHAYGEVPALMRSYGINSGKMWQKLKDAMPADINQDPHG
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA; DNA [C]

Specific reaction: Activates transcription of at least two genes required for unsaturated fatty acid biosynthesis; activates the iclR gene encoding the transcription regulator of the aceBAKoperon which in turn encodes the glyoxylate shunt enzymes Protein + DNA = Protein-DN

General reaction: NA

Inhibitor: Fatty acyl CoA compounds [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA