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The map label for this gene is queC

Identifier: 119774961

GI number: 119774961

Start: 2222863

End: 2223555

Strand: Direct

Name: queC

Synonym: Sama_1826

Alternate gene names: 119774961

Gene position: 2222863-2223555 (Clockwise)

Preceding gene: 119774959

Following gene: 119774962

Centisome position: 51.62

GC content: 53.39

Gene sequence:

>693_bases
ATGTCCAAAGCAGTTGTCGTGTTCAGTGGTGGTCAGGATTCCACTACCTGTCTGGTGCAGGCTCTGTCTCAATTTGATGA
AGTGCATGCCATTACCTTCGATTATGGTCAGCGCCACAGTGAAGAAATTGAAGTCGCCAAAGCGCTGACAAGCGAGCTTG
GCTGTGCGTCCCACAAAATAATGGACGTGTCTTTGCTGGGCGAGCTTGCCATCAGTGCCCTCACCCGTGACGCCATCCCG
GTTTCCCACGAACTAATGGACAACGGCCTGCCCAATACCTTCGTACCTGGTCGCAATATCCTGTTTTTAACCCTGGCTGG
GATTTACGCCTATCAGCTCGGCGCCGATACAGTGATAACCGGCGTATGTGAGACCGACTTTTCAGGCTACCCCGATTGCC
GCAATGACTTCATCAAAGCCATGGAGCAAGCATTGAACCTGGGGATGGACAAGCAGCTTAACATCCACACGCCGCTGATG
TGGCTCAATAAAGCCGAAACCTGGGCGCTTGCCGACCGTTACGGCAAACTCGAACTGGTACGTAACCACACCCTGACCTG
TTACAACGGCATCCGTGGCGATGGTTGCGGAGACTGCCCTGCCTGTCACTTGCGTAAACGTGGCCTTGAGGACTACCTGA
GTAATCGCGATGCAGTAAACGCTGAGCTAACCAAGAAGACAGGCGCCAATTGA

Upstream 100 bases:

>100_bases
TCAAGGGAACTTTCACGCGCCGGAAACCAGCTACTTTGATGCAGAACAGTTGCTGGGATACACTATATCCCCAAAAGTTT
AACTCAGTATCGGTTTTTCC

Downstream 100 bases:

>100_bases
GTCCAACGCCACTCTCAAATCTATTGCCATCAATAGACAAGCAGCTGGTGATGGTTGGCGCGCTCTTGTCAGCGCTGTGC
GCCGCGCTCTATTTATTGCC

Product: ExsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSKAVVVFSGGQDSTTCLVQALSQFDEVHAITFDYGQRHSEEIEVAKALTSELGCASHKIMDVSLLGELAISALTRDAIP
VSHELMDNGLPNTFVPGRNILFLTLAGIYAYQLGADTVITGVCETDFSGYPDCRNDFIKAMEQALNLGMDKQLNIHTPLM
WLNKAETWALADRYGKLELVRNHTLTCYNGIRGDGCGDCPACHLRKRGLEDYLSNRDAVNAELTKKTGAN

Sequences:

>Translated_230_residues
MSKAVVVFSGGQDSTTCLVQALSQFDEVHAITFDYGQRHSEEIEVAKALTSELGCASHKIMDVSLLGELAISALTRDAIP
VSHELMDNGLPNTFVPGRNILFLTLAGIYAYQLGADTVITGVCETDFSGYPDCRNDFIKAMEQALNLGMDKQLNIHTPLM
WLNKAETWALADRYGKLELVRNHTLTCYNGIRGDGCGDCPACHLRKRGLEDYLSNRDAVNAELTKKTGAN
>Mature_229_residues
SKAVVVFSGGQDSTTCLVQALSQFDEVHAITFDYGQRHSEEIEVAKALTSELGCASHKIMDVSLLGELAISALTRDAIPV
SHELMDNGLPNTFVPGRNILFLTLAGIYAYQLGADTVITGVCETDFSGYPDCRNDFIKAMEQALNLGMDKQLNIHTPLMW
LNKAETWALADRYGKLELVRNHTLTCYNGIRGDGCGDCPACHLRKRGLEDYLSNRDAVNAELTKKTGAN

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=229, Percent_Identity=67.2489082969432, Blast_Score=334, Evalue=2e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_SHEAM (A1S6M5)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927701.1
- ProteinModelPortal:   A1S6M5
- SMR:   A1S6M5
- STRING:   A1S6M5
- GeneID:   4604076
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1826
- NMPDR:   fig|326297.7.peg.1719
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- PhylomeDB:   A1S6M5
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25176; Mature: 25045

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKAVVVFSGGQDSTTCLVQALSQFDEVHAITFDYGQRHSEEIEVAKALTSELGCASHKI
CCCEEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHH
MDVSLLGELAISALTRDAIPVSHELMDNGLPNTFVPGRNILFLTLAGIYAYQLGADTVIT
HHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHCCCCHHEE
GVCETDFSGYPDCRNDFIKAMEQALNLGMDKQLNIHTPLMWLNKAETWALADRYGKLELV
EEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHCCCEEEE
RNHTLTCYNGIRGDGCGDCPACHLRKRGLEDYLSNRDAVNAELTKKTGAN
ECCEEEEECCCCCCCCCCCCHHHHHHCCHHHHHCCCCCCCHHHHHCCCCC
>Mature Secondary Structure 
SKAVVVFSGGQDSTTCLVQALSQFDEVHAITFDYGQRHSEEIEVAKALTSELGCASHKI
CCEEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHH
MDVSLLGELAISALTRDAIPVSHELMDNGLPNTFVPGRNILFLTLAGIYAYQLGADTVIT
HHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHCCCCHHEE
GVCETDFSGYPDCRNDFIKAMEQALNLGMDKQLNIHTPLMWLNKAETWALADRYGKLELV
EEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHCCCEEEE
RNHTLTCYNGIRGDGCGDCPACHLRKRGLEDYLSNRDAVNAELTKKTGAN
ECCEEEEECCCCCCCCCCCCHHHHHHCCHHHHHCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA