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The map label for this gene is gra-orf6 [H]

Identifier: 119774899

GI number: 119774899

Start: 2158599

End: 2159357

Strand: Reverse

Name: gra-orf6 [H]

Synonym: Sama_1764

Alternate gene names: 119774899

Gene position: 2159357-2158599 (Counterclockwise)

Preceding gene: 119774904

Following gene: 119774898

Centisome position: 50.15

GC content: 55.99

Gene sequence:

>759_bases
ATGACAGAATCTTACACAGACACGCCCCCTCGCTGGGCACTTATCACAGGTGCAGCCAAACGTATTGGTGCCGCCATTGC
AACCAAACTCCATCAGGAGGGCTGGAATGTGTTTATCCACTGCCACCACTCTGTTGATGAAGCCCAGCGACTTGCTGATG
TGTTATGTCAAAAGCGCGCTGGCTCAGCCCAAGTCATTTGTGCAGACCTCGTACAAGCAGACAGCACCACGCATATAAGG
CATCAGATAGTGCGAAGCGGCGCGTCACTTGCACTGTTGGTGAATAATGCGTCACGGTTTGACAAAGACCCGGCAAACCC
AACCCTTGCGCACGCACAAACCCTGATGGGCGTAAACTGCCTGCAACCTTATCTACTTGCATTTGCCCTGGCGCCACTTT
TGGCGTCAGCGCAGGGCAGTGTGATTAATCTTTGCGATATCCACGGCCAGCGGCCTCTTCGCCAGCATGGATTATACTCA
ATATCAAAGGCTGCACTTGCCATGGCGACGTTGTCATTGGCACAGGAACTGGCGCCCGCGGTGCGGGTCAATGGCATTGC
CCCGGGAGCCATACTCTGGCCAGAAACCGCGGGGGCCAAGCCAAACAAGGTTCTTGCCGAAATCCCCCTCGCCCGTGCCG
GTGCGCCTTCGGATATCGCCAACCTGGTCAGCTATCTTGCCAACGCTGACTACATCAGCGGTCAAATCATTGCTGTTGAC
GGGGGGCGTAGTGCGACCGGCTATCTGGGAGCAGGCTGA

Upstream 100 bases:

>100_bases
TGTATTCCATTGAGGTTTTTGATACAAGAAATCGCCTTTTGCTTTGCCCCGTCAATTTGCCGGGCTACCCTAGTGCCAAA
TAGCCTGAAAGAGACAGGGA

Downstream 100 bases:

>100_bases
TGAAACTCAAGACACAAACCATTTGTTGCCCACATTGCGGACATCACCAACGCATTGAGCTTGATGCATCCGGCGGCGAT
CAGGAGTTCTATGATGATTG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: ORF6 [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MTESYTDTPPRWALITGAAKRIGAAIATKLHQEGWNVFIHCHHSVDEAQRLADVLCQKRAGSAQVICADLVQADSTTHIR
HQIVRSGASLALLVNNASRFDKDPANPTLAHAQTLMGVNCLQPYLLAFALAPLLASAQGSVINLCDIHGQRPLRQHGLYS
ISKAALAMATLSLAQELAPAVRVNGIAPGAILWPETAGAKPNKVLAEIPLARAGAPSDIANLVSYLANADYISGQIIAVD
GGRSATGYLGAG

Sequences:

>Translated_252_residues
MTESYTDTPPRWALITGAAKRIGAAIATKLHQEGWNVFIHCHHSVDEAQRLADVLCQKRAGSAQVICADLVQADSTTHIR
HQIVRSGASLALLVNNASRFDKDPANPTLAHAQTLMGVNCLQPYLLAFALAPLLASAQGSVINLCDIHGQRPLRQHGLYS
ISKAALAMATLSLAQELAPAVRVNGIAPGAILWPETAGAKPNKVLAEIPLARAGAPSDIANLVSYLANADYISGQIIAVD
GGRSATGYLGAG
>Mature_251_residues
TESYTDTPPRWALITGAAKRIGAAIATKLHQEGWNVFIHCHHSVDEAQRLADVLCQKRAGSAQVICADLVQADSTTHIRH
QIVRSGASLALLVNNASRFDKDPANPTLAHAQTLMGVNCLQPYLLAFALAPLLASAQGSVINLCDIHGQRPLRQHGLYSI
SKAALAMATLSLAQELAPAVRVNGIAPGAILWPETAGAKPNKVLAEIPLARAGAPSDIANLVSYLANADYISGQIIAVDG
GRSATGYLGAG

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=29.2181069958848, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=29.5546558704453, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI59889578, Length=212, Percent_Identity=31.1320754716981, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI40254992, Length=115, Percent_Identity=33.0434782608696, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787891, Length=245, Percent_Identity=31.8367346938775, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1788459, Length=240, Percent_Identity=29.1666666666667, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=27.2357723577236, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=28.2157676348548, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=29.2, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=27.1317829457364, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=27.7551020408163, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=29.3436293436293, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=28.1368821292776, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=274, Percent_Identity=29.1970802919708, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=259, Percent_Identity=29.3436293436293, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=30.1526717557252, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=268, Percent_Identity=31.3432835820896, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=30.2325581395349, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=31.3008130081301, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=273, Percent_Identity=26.7399267399267, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=26.7206477732794, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=263, Percent_Identity=28.1368821292776, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=28.0155642023346, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=27.0161290322581, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=29.6992481203008, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=256, Percent_Identity=27.34375, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=258, Percent_Identity=28.6821705426357, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=28.2786885245902, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=27.7777777777778, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=27.3092369477912, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=26.2745098039216, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=27.4193548387097, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26434; Mature: 26302

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESYTDTPPRWALITGAAKRIGAAIATKLHQEGWNVFIHCHHSVDEAQRLADVLCQKRA
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHCC
GSAQVICADLVQADSTTHIRHQIVRSGASLALLVNNASRFDKDPANPTLAHAQTLMGVNC
CCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCHHCCCCCCCCHHHHHHHHHHHHH
LQPYLLAFALAPLLASAQGSVINLCDIHGQRPLRQHGLYSISKAALAMATLSLAQELAPA
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VRVNGIAPGAILWPETAGAKPNKVLAEIPLARAGAPSDIANLVSYLANADYISGQIIAVD
HEECCCCCCCEECCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEE
GGRSATGYLGAG
CCCCCCCCCCCC
>Mature Secondary Structure 
TESYTDTPPRWALITGAAKRIGAAIATKLHQEGWNVFIHCHHSVDEAQRLADVLCQKRA
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHCC
GSAQVICADLVQADSTTHIRHQIVRSGASLALLVNNASRFDKDPANPTLAHAQTLMGVNC
CCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCHHCCCCCCCCHHHHHHHHHHHHH
LQPYLLAFALAPLLASAQGSVINLCDIHGQRPLRQHGLYSISKAALAMATLSLAQELAPA
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VRVNGIAPGAILWPETAGAKPNKVLAEIPLARAGAPSDIANLVSYLANADYISGQIIAVD
HEECCCCCCCEECCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEE
GGRSATGYLGAG
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2583128; 9831526 [H]