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The map label for this gene is trxB [H]

Identifier: 119774904

GI number: 119774904

Start: 2162836

End: 2163789

Strand: Reverse

Name: trxB [H]

Synonym: Sama_1769

Alternate gene names: 119774904

Gene position: 2163789-2162836 (Counterclockwise)

Preceding gene: 119774905

Following gene: 119774899

Centisome position: 50.25

GC content: 52.83

Gene sequence:

>954_bases
ATGAGCCAAGCCAAACACAGCCAACTGCTGATCCTCGGATCGGGCCCAGCTGGCTACACTGCCGCCGTCTACGCTGCACG
TGCAAACCTGAACCCAGTGATGATCACAGGTCTCCAACAAGGTGGTCAGCTGACTACCACGACCGAAGTTGAAAACTGGC
CAGGTGATGCCGAAGGTTTGACCGGACCAGGCCTGATGGCCCGTATGCAGGAGCATGCCGAAAAGTTCAACACCGAAATT
ATCTTCGACCATATTAACGAAGTGACCCTCACTGAACGTCCTTTCCGCTTGAAAGGTGATAATGGCGAGTACACCTGTGA
TGCGCTTATCATTGCCACCGGCGCATCGGCCAAGTACCTGGGGCTGCCTTCTGAAGATGCTTTTAAAGGTCGCGGCGTTT
CAGCCTGCGCTACCTGTGATGGTTTTTTCTATCGCAATCAAAAGGTCGCAGTAATCGGTGGTGGTAACACCGCGGTGGAA
GAGGCCCTGTATCTGTCCAACATCGCCTCTGAAGTTCACCTCATCCACCGTCGTGACAGCTTCCGCTCAGAGAAAATTCT
GATTGACCGTCTGATGGACAAGGTTGCAAACGGCAACATCATTCTGCATTTGGACAAGACGCTGGATGAAGTGGTGGGCG
ACAATATGGGTGTGACCGGTGTTAAGCTGAAATCCACCAAAGATGACTCTACTGAAGCATTTGATGTTGCGGGTGTTTTC
GTCGCTATTGGTCACAGCCCCAATACCGGCATCTTCGAGGGTCAGCTGGAGATGAACAATGGTTACATCAAGGTGCAAAG
CGGTCTGAACGGCAATGCAACCCAAACCAGCATCGAGGGCGTATTTGCTGCCGGTGATGTGATGGACCAACACTATCGTC
AGGCCATTACCTCAGCCGGTACCGGCTGTATGGCTGCACTGGATGCCGAGCGTTATTTGGACGCCAAGCACTGA

Upstream 100 bases:

>100_bases
AGATAGATTAGGATCATCTAAGACTTCACGCTCGATGGCCTTTACCCTTACACGTAAATTCCCTACAATCCCAGCAATTT
GCCAAGGCACGGAGAATAAA

Downstream 100 bases:

>100_bases
TAGGTTCCTTAAAAATAAAAAGCCGGCTACATGCCGGCTTTTTATTGCGGGTGTTATTAATGATTAAACAACATAAATCA
GACCCACAAAAAAAGGGACC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSQAKHSQLLILGSGPAGYTAAVYAARANLNPVMITGLQQGGQLTTTTEVENWPGDAEGLTGPGLMARMQEHAEKFNTEI
IFDHINEVTLTERPFRLKGDNGEYTCDALIIATGASAKYLGLPSEDAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
EALYLSNIASEVHLIHRRDSFRSEKILIDRLMDKVANGNIILHLDKTLDEVVGDNMGVTGVKLKSTKDDSTEAFDVAGVF
VAIGHSPNTGIFEGQLEMNNGYIKVQSGLNGNATQTSIEGVFAAGDVMDQHYRQAITSAGTGCMAALDAERYLDAKH

Sequences:

>Translated_317_residues
MSQAKHSQLLILGSGPAGYTAAVYAARANLNPVMITGLQQGGQLTTTTEVENWPGDAEGLTGPGLMARMQEHAEKFNTEI
IFDHINEVTLTERPFRLKGDNGEYTCDALIIATGASAKYLGLPSEDAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
EALYLSNIASEVHLIHRRDSFRSEKILIDRLMDKVANGNIILHLDKTLDEVVGDNMGVTGVKLKSTKDDSTEAFDVAGVF
VAIGHSPNTGIFEGQLEMNNGYIKVQSGLNGNATQTSIEGVFAAGDVMDQHYRQAITSAGTGCMAALDAERYLDAKH
>Mature_316_residues
SQAKHSQLLILGSGPAGYTAAVYAARANLNPVMITGLQQGGQLTTTTEVENWPGDAEGLTGPGLMARMQEHAEKFNTEII
FDHINEVTLTERPFRLKGDNGEYTCDALIIATGASAKYLGLPSEDAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEE
ALYLSNIASEVHLIHRRDSFRSEKILIDRLMDKVANGNIILHLDKTLDEVVGDNMGVTGVKLKSTKDDSTEAFDVAGVFV
AIGHSPNTGIFEGQLEMNNGYIKVQSGLNGNATQTSIEGVFAAGDVMDQHYRQAITSAGTGCMAALDAERYLDAKH

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=83.1746031746032, Blast_Score=544, Evalue=1e-156,
Organism=Escherichia coli, GI87081763, Length=314, Percent_Identity=33.1210191082803, Blast_Score=137, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6321898, Length=329, Percent_Identity=46.2006079027356, Blast_Score=283, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6320560, Length=320, Percent_Identity=46.25, Blast_Score=275, Evalue=5e-75,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33922; Mature: 33790

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQAKHSQLLILGSGPAGYTAAVYAARANLNPVMITGLQQGGQLTTTTEVENWPGDAEGL
CCCCCCCEEEEEECCCCCCEEEEEEEECCCCEEEEEEECCCCEEEEEEECCCCCCCCCCC
TGPGLMARMQEHAEKFNTEIIFDHINEVTLTERPFRLKGDNGEYTCDALIIATGASAKYL
CCCHHHHHHHHHHHHHCCEEEEECCCCEEECCCCEEEECCCCCEEEEEEEEEECCCEEEE
GLPSEDAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDS
CCCCCCCCCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHEEECCCC
FRSEKILIDRLMDKVANGNIILHLDKTLDEVVGDNMGVTGVKLKSTKDDSTEAFDVAGVF
CCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEEE
VAIGHSPNTGIFEGQLEMNNGYIKVQSGLNGNATQTSIEGVFAAGDVMDQHYRQAITSAG
EEECCCCCCCEEEEEEEECCCEEEEECCCCCCCCEEECCEEEEHHHHHHHHHHHHHHHCC
TGCMAALDAERYLDAKH
CCCEEECCHHHHCCCCC
>Mature Secondary Structure 
SQAKHSQLLILGSGPAGYTAAVYAARANLNPVMITGLQQGGQLTTTTEVENWPGDAEGL
CCCCCCEEEEEECCCCCCEEEEEEEECCCCEEEEEEECCCCEEEEEEECCCCCCCCCCC
TGPGLMARMQEHAEKFNTEIIFDHINEVTLTERPFRLKGDNGEYTCDALIIATGASAKYL
CCCHHHHHHHHHHHHHCCEEEEECCCCEEECCCCEEEECCCCCEEEEEEEEEECCCEEEE
GLPSEDAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDS
CCCCCCCCCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHEEECCCC
FRSEKILIDRLMDKVANGNIILHLDKTLDEVVGDNMGVTGVKLKSTKDDSTEAFDVAGVF
CCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEEE
VAIGHSPNTGIFEGQLEMNNGYIKVQSGLNGNATQTSIEGVFAAGDVMDQHYRQAITSAG
EEECCCCCCCEEEEEEEECCCEEEEECCCCCCCCEEECCEEEEHHHHHHHHHHHHHHHCC
TGCMAALDAERYLDAKH
CCCEEECCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]