BacMap

Definition	Shewanella amazonensis SB2B chromosome, complete genome.
Accession	NC_008700
Length	4,306,142

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The map label for this gene is fadH [H]

Identifier: 119774876

GI number: 119774876

Start: 2130596

End: 2131414

Strand: Direct

Name: fadH [H]

Synonym: Sama_1741

Alternate gene names: 119774876

Gene position: 2130596-2131414 (Clockwise)

Preceding gene: 119774875

Following gene: 119774877

Centisome position: 49.48

GC content: 55.07

Gene sequence:

>819_bases
ATGTTCGACTTTAACGGGAAAAACATTTTGGTGGTCGGCGGTACCAGTGGCATCAACCTGGGCATCGCGCGAGCCTTTGC
GAAGGCGGGCGGCCGGGTAGCGGTAGCGAGTCGCAGTCAGGACAAAGTCGATGCGGCGCTTACTCTCTTGAGTGGAGACA
ATCCTAAGGTAACGCCGCTGGGCGCCAGTTTCGACGTGCGTGATAATGACGCTGTGCTCTTCGGTATCGCCGCATTGCAT
CATCAGCTAGGCACCATAGATGTACTTATCAGCGGCGCTGCCGGTAATTTCCCGGCTCCTGCTGCCGGAATGAGTGCCAA
TGGTTTCAAGTCGGTTGTGGACATTGACCTCCTTGGCAGTTTTCAGGTGCTGAAAGCCTGTTACCCTTTGTTGTCACGCC
CAGGTGTCATTCTGCAGATTTCAGCTCCTCAGGCCTTTGTCCCCATGCCAATGCAGGCCCATGTGTGCGCTGCCAAGGCT
GGTGTTGATATGCTCACCCGAACACTTGCGATGGAATGGTCCCACGAAGGGATTCGGATTAACTCGATAGTTCCTGGTCC
AATTGAAGGCACAGAAGGGTTTGACAGACTTGCTCCCGGCGATGCCCTCAAGGCACGGGTTGCGCAAAGTGTGCCCCTTG
GACGAAACGGCAGTATCACAGATATCGCAAACTGCGCACTGTTTCTGGCTTCTGAGTTCGCCAGTTACATCAATGGCGTG
GTTTTACCCGTGGATGGCGGCTGGTCACTTGGTGGAGCCAGCATGGCCATGACAGAGCTTGGGCAACTCATATCAAAGTC
GGGCAAGGGCTCAGCTTAA

Upstream 100 bases:

>100_bases
CTGACGGAAATTCACCAGTCAATCCGCGGAATATAAACCACAGGGCCACAATAACCCGCACTCACGGCTGAAACGCAATT
AGCGCTGACAAGGAGTTAAG

Downstream 100 bases:

>100_bases
GCCGGGCTACTCAAATAGGCCCGCATCAGGTTTAAAAAAGTACAACGGAATAGATTCCAATTAAAGAGAGACCATCATGG
CTAACGCATTACAGGAGCAA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MFDFNGKNILVVGGTSGINLGIARAFAKAGGRVAVASRSQDKVDAALTLLSGDNPKVTPLGASFDVRDNDAVLFGIAALH
HQLGTIDVLISGAAGNFPAPAAGMSANGFKSVVDIDLLGSFQVLKACYPLLSRPGVILQISAPQAFVPMPMQAHVCAAKA
GVDMLTRTLAMEWSHEGIRINSIVPGPIEGTEGFDRLAPGDALKARVAQSVPLGRNGSITDIANCALFLASEFASYINGV
VLPVDGGWSLGGASMAMTELGQLISKSGKGSA

Sequences:

>Translated_272_residues
MFDFNGKNILVVGGTSGINLGIARAFAKAGGRVAVASRSQDKVDAALTLLSGDNPKVTPLGASFDVRDNDAVLFGIAALH
HQLGTIDVLISGAAGNFPAPAAGMSANGFKSVVDIDLLGSFQVLKACYPLLSRPGVILQISAPQAFVPMPMQAHVCAAKA
GVDMLTRTLAMEWSHEGIRINSIVPGPIEGTEGFDRLAPGDALKARVAQSVPLGRNGSITDIANCALFLASEFASYINGV
VLPVDGGWSLGGASMAMTELGQLISKSGKGSA
>Mature_272_residues
MFDFNGKNILVVGGTSGINLGIARAFAKAGGRVAVASRSQDKVDAALTLLSGDNPKVTPLGASFDVRDNDAVLFGIAALH
HQLGTIDVLISGAAGNFPAPAAGMSANGFKSVVDIDLLGSFQVLKACYPLLSRPGVILQISAPQAFVPMPMQAHVCAAKA
GVDMLTRTLAMEWSHEGIRINSIVPGPIEGTEGFDRLAPGDALKARVAQSVPLGRNGSITDIANCALFLASEFASYINGV
VLPVDGGWSLGGASMAMTELGQLISKSGKGSA

Specific function: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=43.7246963562753, Blast_Score=167, Evalue=7e-42,
Organism=Homo sapiens, GI4503301, Length=222, Percent_Identity=34.6846846846847, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=30.5882352941176, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=32.2448979591837, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=27.1255060728745, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI5031737, Length=240, Percent_Identity=29.5833333333333, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI59889578, Length=240, Percent_Identity=31.25, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=28.5123966942149, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI33667109, Length=182, Percent_Identity=29.6703296703297, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=26.5873015873016, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI15277342, Length=147, Percent_Identity=34.0136054421769, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=29.4573643410853, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=25.3012048192771, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=30.2788844621514, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789378, Length=259, Percent_Identity=27.4131274131274, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=27.0588235294118, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788459, Length=188, Percent_Identity=29.2553191489362, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=28.2868525896414, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=26.7441860465116, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=24.3137254901961, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789057, Length=250, Percent_Identity=25.6, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787545, Length=273, Percent_Identity=27.1062271062271, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=25.8064516129032, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17561272, Length=238, Percent_Identity=36.1344537815126, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17536025, Length=253, Percent_Identity=32.0158102766798, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=31.7647058823529, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=28.6852589641434, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=30.2788844621514, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=271, Percent_Identity=28.4132841328413, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=245, Percent_Identity=26.530612244898, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=268, Percent_Identity=28.7313432835821, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=244, Percent_Identity=25.4098360655738, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=29.8507462686567, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=27.0676691729323, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=28.0442804428044, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=29.9212598425197, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=288, Percent_Identity=27.4305555555556, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=27.0491803278689, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=27.5471698113208, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=252, Percent_Identity=29.3650793650794, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=27.8810408921933, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=26.1194029850746, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=26.4925373134328, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=27.7153558052434, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=26.865671641791, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=270, Percent_Identity=27.4074074074074, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=25.8555133079848, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=25.5555555555556, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17508651, Length=251, Percent_Identity=29.4820717131474, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=42.6877470355731, Blast_Score=171, Evalue=1e-43,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=30.9803921568627, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=28.4046692607004, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=27.843137254902, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=28.3464566929134, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=28.9156626506024, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=25.4032258064516, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=27.843137254902, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 27873; Mature: 27873

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDFNGKNILVVGGTSGINLGIARAFAKAGGRVAVASRSQDKVDAALTLLSGDNPKVTPL
CCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHEEEEEECCCCCEEEC
GASFDVRDNDAVLFGIAALHHQLGTIDVLISGAAGNFPAPAAGMSANGFKSVVDIDLLGS
CCEEECCCCCEEEEHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCH
FQVLKACYPLLSRPGVILQISAPQAFVPMPMQAHVCAAKAGVDMLTRTLAMEWSHEGIRI
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
NSIVPGPIEGTEGFDRLAPGDALKARVAQSVPLGRNGSITDIANCALFLASEFASYINGV
ECCCCCCCCCCCCCHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCE
VLPVDGGWSLGGASMAMTELGQLISKSGKGSA
EEEECCCCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFDFNGKNILVVGGTSGINLGIARAFAKAGGRVAVASRSQDKVDAALTLLSGDNPKVTPL
CCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHEEEEEECCCCCEEEC
GASFDVRDNDAVLFGIAALHHQLGTIDVLISGAAGNFPAPAAGMSANGFKSVVDIDLLGS
CCEEECCCCCEEEEHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCH
FQVLKACYPLLSRPGVILQISAPQAFVPMPMQAHVCAAKAGVDMLTRTLAMEWSHEGIRI
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
NSIVPGPIEGTEGFDRLAPGDALKARVAQSVPLGRNGSITDIANCALFLASEFASYINGV
ECCCCCCCCCCCCCHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCE
VLPVDGGWSLGGASMAMTELGQLISKSGKGSA
EEEECCCCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]