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The map label for this gene is apbE [H]

Identifier: 119774819

GI number: 119774819

Start: 2057082

End: 2057996

Strand: Direct

Name: apbE [H]

Synonym: Sama_1683

Alternate gene names: 119774819

Gene position: 2057082-2057996 (Clockwise)

Preceding gene: 119774818

Following gene: 119774821

Centisome position: 47.77

GC content: 56.72

Gene sequence:

>915_bases
ATGGCAGGCAGCAAAGCGATTACTAGGCGGATACACTTCAGCGCCATGGCGAGTGACTGTGAACTGCTGTTTATCGGCGC
CAGTGACGCACAGGCCAACACCTTTGCCGAACTTGCCATCGCCGAAGTGCGGCGCATCGAAGCCAAGTTCAGCCGCTATA
GACCCGAGAGCGAGCTTAGTCGCATCAACGGTCTCGCTGGCAGCCACATCCCCATTGATCCCGAGACTGATGGGCTGCTT
AAATTCGCTGCCGACTGCTTCAGGCTTTCAGGCGGGCTTTTTGATGTCACCACAGCACCACTGCAACAGCTGTGGCGGTT
TGGCTTTAAACATCATGGCCTTAACAATGAGTGTTTCCCGCAAGAGGCGCAGATAAAGGCGGCACTCGACCACATTGGCT
TTGAACGGTTGGGGATCGAAAACAATTCCCTCTGGCTTCCCGCTGGCATGAGCCTCGATTTTGGGGGGATTGCCAAAGAG
TATGCTGCCGACAGAGCGCTGCTTTTGATAGAACGCCAGGCCCGGGACCGCGGACTTGATGTTGCTGTGCTGGTAAACCT
TGGCGGTGATATAGCCGCAAGCCGATACCCCTGGCAGATTGGGGTTGAAGGGGTCCATGCCAAATGTGACTCTGATCTGC
TCAAGGCAGAAGCTTCGGGTCTTATCGCGTTCCCCGGTGGCGGCCTTGCAACCAGCGGTGATACCAAGCGCTTTGTGCTG
GTGGACGGTAAGCGTGTTGGCCATATCCTGTCACCCAAAACCGGTTATCCGGTGCCGGATTCGCCGCGTTCTGTCACGGT
ACTGGCGCCCAGTGCGTCGGCCGCGGGAATGTTGTCTACCATGGCCATGCTAAAGGGCGAGGGTGCTGAGGATTTTTTAA
GGGGCGAAGGCCTTGTTTATCTGGTGCAGCGCTGA

Upstream 100 bases:

>100_bases
GAAGGACTGCAGGGGCTTGATGTGTACCCTGAGCTTAATGCCGCCATGTTGCAGCTTAACTACTCGTGGCGTTAAGTATT
ATGTCGTGGAATTAAGTCTT

Downstream 100 bases:

>100_bases
GTGTGATTGTTGGGGAGCAGGAAACATAAATAGAAAAGCCGCCCATAAGGCGGCTTTATCATTTTTTCGCTAATTGCTTG
TACGCTATTAGAAGTTAGCG

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MAGSKAITRRIHFSAMASDCELLFIGASDAQANTFAELAIAEVRRIEAKFSRYRPESELSRINGLAGSHIPIDPETDGLL
KFAADCFRLSGGLFDVTTAPLQQLWRFGFKHHGLNNECFPQEAQIKAALDHIGFERLGIENNSLWLPAGMSLDFGGIAKE
YAADRALLLIERQARDRGLDVAVLVNLGGDIAASRYPWQIGVEGVHAKCDSDLLKAEASGLIAFPGGGLATSGDTKRFVL
VDGKRVGHILSPKTGYPVPDSPRSVTVLAPSASAAGMLSTMAMLKGEGAEDFLRGEGLVYLVQR

Sequences:

>Translated_304_residues
MAGSKAITRRIHFSAMASDCELLFIGASDAQANTFAELAIAEVRRIEAKFSRYRPESELSRINGLAGSHIPIDPETDGLL
KFAADCFRLSGGLFDVTTAPLQQLWRFGFKHHGLNNECFPQEAQIKAALDHIGFERLGIENNSLWLPAGMSLDFGGIAKE
YAADRALLLIERQARDRGLDVAVLVNLGGDIAASRYPWQIGVEGVHAKCDSDLLKAEASGLIAFPGGGLATSGDTKRFVL
VDGKRVGHILSPKTGYPVPDSPRSVTVLAPSASAAGMLSTMAMLKGEGAEDFLRGEGLVYLVQR
>Mature_303_residues
AGSKAITRRIHFSAMASDCELLFIGASDAQANTFAELAIAEVRRIEAKFSRYRPESELSRINGLAGSHIPIDPETDGLLK
FAADCFRLSGGLFDVTTAPLQQLWRFGFKHHGLNNECFPQEAQIKAALDHIGFERLGIENNSLWLPAGMSLDFGGIAKEY
AADRALLLIERQARDRGLDVAVLVNLGGDIAASRYPWQIGVEGVHAKCDSDLLKAEASGLIAFPGGGLATSGDTKRFVLV
DGKRVGHILSPKTGYPVPDSPRSVTVLAPSASAAGMLSTMAMLKGEGAEDFLRGEGLVYLVQR

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=271, Percent_Identity=28.4132841328413, Blast_Score=97, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 32642; Mature: 32510

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSKAITRRIHFSAMASDCELLFIGASDAQANTFAELAIAEVRRIEAKFSRYRPESELS
CCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RINGLAGSHIPIDPETDGLLKFAADCFRLSGGLFDVTTAPLQQLWRFGFKHHGLNNECFP
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCCCCCCC
QEAQIKAALDHIGFERLGIENNSLWLPAGMSLDFGGIAKEYAADRALLLIERQARDRGLD
CHHHHHHHHHHCCHHHCCCCCCCEEECCCCCCCCCCHHHHHHCCCEEEEEEEHHHCCCCE
VAVLVNLGGDIAASRYPWQIGVEGVHAKCDSDLLKAEASGLIAFPGGGLATSGDTKRFVL
EEEEEECCCCCCCCCCCEEECCCCEECCCCHHHHHHCCCCEEEECCCCEECCCCCEEEEE
VDGKRVGHILSPKTGYPVPDSPRSVTVLAPSASAAGMLSTMAMLKGEGAEDFLRGEGLVY
ECCCCCCEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCHHHHHCCCCEEE
LVQR
EEEC
>Mature Secondary Structure 
AGSKAITRRIHFSAMASDCELLFIGASDAQANTFAELAIAEVRRIEAKFSRYRPESELS
CCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RINGLAGSHIPIDPETDGLLKFAADCFRLSGGLFDVTTAPLQQLWRFGFKHHGLNNECFP
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCCCCCCC
QEAQIKAALDHIGFERLGIENNSLWLPAGMSLDFGGIAKEYAADRALLLIERQARDRGLD
CHHHHHHHHHHCCHHHCCCCCCCEEECCCCCCCCCCHHHHHHCCCEEEEEEEHHHCCCCE
VAVLVNLGGDIAASRYPWQIGVEGVHAKCDSDLLKAEASGLIAFPGGGLATSGDTKRFVL
EEEEEECCCCCCCCCCCEEECCCCEECCCCHHHHHHCCCCEEEECCCCEECCCCCEEEEE
VDGKRVGHILSPKTGYPVPDSPRSVTVLAPSASAAGMLSTMAMLKGEGAEDFLRGEGLVY
ECCCCCCEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCHHHHHCCCCEEE
LVQR
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]