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The map label for this gene is galR [H]

Identifier: 119774537

GI number: 119774537

Start: 1698830

End: 1699828

Strand: Reverse

Name: galR [H]

Synonym: Sama_1400

Alternate gene names: 119774537

Gene position: 1699828-1698830 (Counterclockwise)

Preceding gene: 119774538

Following gene: 119774536

Centisome position: 39.47

GC content: 55.96

Gene sequence:

>999_bases
ATGGCCACAATTTATGACGTTTCCTTTCTGGCAGGCGTGTCGCTGGCGACCGTCTCCAGGGTGGTGAACAACACCGGCAA
AGTCAGTGACAAGACCCGTCAAAAGGTCCACGATGCCATGGCAAAGCTGGACTACCGCCCCAATACCATCGCTCAGTCTT
TGGCCTCCAACCGCTCCAACAGTATTGGTGTGCTGGTGTCACAGCTGGATGGTCCCTTCTACGGCCCCATGATGCGGGAG
GTGGAGTCGGCACTGCGCGCTGCCAATAAGCACGTTATCATCGCAGCCGGCCACAGCGATGCGGCACAGGAAAAAGATGG
TGTTGAGTTTCTGCTGTCCCGGGGGTGTGATGCCCTGATTGTGGATGCCGAAATTCTCTCCAACGGCTATTTGGTTGAGC
TGTGTCAGGGGAAAACCCCGGTGGTGCTCATAAACCGGCATGTGGATGGTATCGATGAGCGCTGCGTACACCTGAATAAC
CTTCAGGGTGGTTTGCTCGCCAGCCGCCATGTTCTGGAAAAGGGCCACAAACAGATAGCCTATATCTCCGGGCCGCTGTT
TAAGCTCGATGCCAGAGAACGTCTCGAAGGCCATCGTCAGGCATTGGCAGAGCAAGGCATCGCCTTTGACGAAAACCTCT
TTTATGAAGGGGACTTTCGTGAAGAAGGCGGCTATGAGGCCATGGCTCAGTTGCTCTCACGGGGGCGGGACTTTACTGCC
GTGGTGTGTGCAAACGATCAGATGGCATCGGGTGCCATAGCCCAGTGTTTGGAGCGGGGTCTGCGGGTGCCCGAAGACAT
CTCCTTCGTGGGATTCGATAATATCCCCTTCCCCCGTTATATCTCGCCCAAACTGACCACTGTGTGTAACCCCATTCAGG
ACATGGGACGCATGGCGGCCCACTGGGTGCTGCGCGAAGTGTACGACCAAACCGACGTGACGTTTTGCCACCGCTTTGAG
CCGGAGTTGGTGGTTCGGGATTCTGTTATCACACGTTAA

Upstream 100 bases:

>100_bases
GACACTATACACTGGACAGCCAACGCGTTGCCGAGATCAGCGTATCTTTGCAACAAAAGCATTCAGGCACATAGATGTAG
TACAAGGAAAGCCCGCGCGT

Downstream 100 bases:

>100_bases
GCATTTTTATCATGACCGGGGTGAGCCAACGTGCTCACCTTTTTTTATTGCAGAAAAAATTCTTTTAAAAACAAAAGAAA
GAAACCAATTCAAACACTCA

Product: periplasmic binding protein/LacI transcriptional regulator

Products: NA

Alternate protein names: Galactose operon repressor [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MATIYDVSFLAGVSLATVSRVVNNTGKVSDKTRQKVHDAMAKLDYRPNTIAQSLASNRSNSIGVLVSQLDGPFYGPMMRE
VESALRAANKHVIIAAGHSDAAQEKDGVEFLLSRGCDALIVDAEILSNGYLVELCQGKTPVVLINRHVDGIDERCVHLNN
LQGGLLASRHVLEKGHKQIAYISGPLFKLDARERLEGHRQALAEQGIAFDENLFYEGDFREEGGYEAMAQLLSRGRDFTA
VVCANDQMASGAIAQCLERGLRVPEDISFVGFDNIPFPRYISPKLTTVCNPIQDMGRMAAHWVLREVYDQTDVTFCHRFE
PELVVRDSVITR

Sequences:

>Translated_332_residues
MATIYDVSFLAGVSLATVSRVVNNTGKVSDKTRQKVHDAMAKLDYRPNTIAQSLASNRSNSIGVLVSQLDGPFYGPMMRE
VESALRAANKHVIIAAGHSDAAQEKDGVEFLLSRGCDALIVDAEILSNGYLVELCQGKTPVVLINRHVDGIDERCVHLNN
LQGGLLASRHVLEKGHKQIAYISGPLFKLDARERLEGHRQALAEQGIAFDENLFYEGDFREEGGYEAMAQLLSRGRDFTA
VVCANDQMASGAIAQCLERGLRVPEDISFVGFDNIPFPRYISPKLTTVCNPIQDMGRMAAHWVLREVYDQTDVTFCHRFE
PELVVRDSVITR
>Mature_331_residues
ATIYDVSFLAGVSLATVSRVVNNTGKVSDKTRQKVHDAMAKLDYRPNTIAQSLASNRSNSIGVLVSQLDGPFYGPMMREV
ESALRAANKHVIIAAGHSDAAQEKDGVEFLLSRGCDALIVDAEILSNGYLVELCQGKTPVVLINRHVDGIDERCVHLNNL
QGGLLASRHVLEKGHKQIAYISGPLFKLDARERLEGHRQALAEQGIAFDENLFYEGDFREEGGYEAMAQLLSRGRDFTAV
VCANDQMASGAIAQCLERGLRVPEDISFVGFDNIPFPRYISPKLTTVCNPIQDMGRMAAHWVLREVYDQTDVTFCHRFEP
ELVVRDSVITR

Specific function: Repressor of the galactose operon. Binds galactose as an inducer [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789202, Length=331, Percent_Identity=40.785498489426, Blast_Score=249, Evalue=1e-67,
Organism=Escherichia coli, GI1788474, Length=332, Percent_Identity=40.6626506024096, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1790369, Length=331, Percent_Identity=34.1389728096677, Blast_Score=184, Evalue=9e-48,
Organism=Escherichia coli, GI1787948, Length=331, Percent_Identity=32.9305135951662, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1789068, Length=338, Percent_Identity=31.0650887573964, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1790194, Length=312, Percent_Identity=33.3333333333333, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1786540, Length=305, Percent_Identity=33.7704918032787, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787906, Length=317, Percent_Identity=27.4447949526814, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1787580, Length=315, Percent_Identity=25.0793650793651, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI48994940, Length=310, Percent_Identity=26.4516129032258, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790715, Length=310, Percent_Identity=29.0322580645161, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1789456, Length=324, Percent_Identity=26.5432098765432, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1786268, Length=281, Percent_Identity=24.9110320284698, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790689, Length=322, Percent_Identity=22.0496894409938, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790192, Length=225, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36694; Mature: 36563

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIYDVSFLAGVSLATVSRVVNNTGKVSDKTRQKVHDAMAKLDYRPNTIAQSLASNRSN
CCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
SIGVLVSQLDGPFYGPMMREVESALRAANKHVIIAAGHSDAAQEKDGVEFLLSRGCDALI
CCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEE
VDAEILSNGYLVELCQGKTPVVLINRHVDGIDERCVHLNNLQGGLLASRHVLEKGHKQIA
EEHHHHCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCEEE
YISGPLFKLDARERLEGHRQALAEQGIAFDENLFYEGDFREEGGYEAMAQLLSRGRDFTA
EECCCEEEECHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHCCCCEEE
VVCANDQMASGAIAQCLERGLRVPEDISFVGFDNIPFPRYISPKLTTVCNPIQDMGRMAA
EEECCCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
HWVLREVYDQTDVTFCHRFEPELVVRDSVITR
HHHHHHHHCCCCCEEEECCCCCEEECCHHCCC
>Mature Secondary Structure 
ATIYDVSFLAGVSLATVSRVVNNTGKVSDKTRQKVHDAMAKLDYRPNTIAQSLASNRSN
CEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
SIGVLVSQLDGPFYGPMMREVESALRAANKHVIIAAGHSDAAQEKDGVEFLLSRGCDALI
CCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEE
VDAEILSNGYLVELCQGKTPVVLINRHVDGIDERCVHLNNLQGGLLASRHVLEKGHKQIA
EEHHHHCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCEEE
YISGPLFKLDARERLEGHRQALAEQGIAFDENLFYEGDFREEGGYEAMAQLLSRGRDFTA
EECCCEEEECHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHCCCCEEE
VVCANDQMASGAIAQCLERGLRVPEDISFVGFDNIPFPRYISPKLTTVCNPIQDMGRMAA
EEECCCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
HWVLREVYDQTDVTFCHRFEPELVVRDSVITR
HHHHHHHHCCCCCEEEECCCCCEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6283521; 9278503; 6350601; 8188660; 8982002 [H]