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The map label for this gene is scoA [H]

Identifier: 119774494

GI number: 119774494

Start: 1645859

End: 1646560

Strand: Reverse

Name: scoA [H]

Synonym: Sama_1357

Alternate gene names: 119774494

Gene position: 1646560-1645859 (Counterclockwise)

Preceding gene: 119774495

Following gene: 119774493

Centisome position: 38.24

GC content: 56.27

Gene sequence:

>702_bases
ATGGCTGGACTCTACAAGGTCGTCGACAGTTACGACCAGGCCCTGGCGGGCCTAACTGACAATATGACCATTATGGTGGG
CGGATTTGGCCTGTGCGGTATTCCGGAAGGCCTGATTAACCAGATGGTAAAACTTGGCACCAAGGGGCTGACTGCCATTT
CCAACAACGCAGGGGTGGACGACTTTGGTCTGGGGCTGTTGCTGCAAAACAAGCAGATCAGCACCATGATAGCCTCCTAC
GTGGGTGAAAACGCCACCTTCGAGCGCCAGATGCTGAGCGGCGAGCTGAACGTTATCCTCACCCCACAGGGCACACTGGC
TGAAAAAATCCGTGCCGGCGGCGCCGGTATCCCGGCTTTCTTTACCGCCACTGGCTACGGCACTCCGGTTGCCGAGGGTA
AAGAAACCCGCGAAATCAAGGGTCGCCACTATGTGCTGGAAGAGTCCCTGACCGCCGATTTTGCCCTTATCCGCGCCTGG
AAGGCCGATACCATGGGTAACCTGGTGTTCCGTAAAACCGCCGCCAACTTCAACCCCATGATGGCCACCGCCGGTAAAAT
CACCGTGGTGGAAGTGGAAGAAATTGTTGAGCCGGGCGAGCTTGACCCGGACCATATCCACACCCCGGGCATTTATGTGG
ATCGCATCATCAAAGGCAGCTTTGAGAAGCGTATCGAACAGCGCACCGTGAAAAAGGCTTAA

Upstream 100 bases:

>100_bases
CAAGATAACAATAACTATCTCCTGCCCCACAGCGGGCAGGCGAATAAAGCACAGCACACCACCTGACATCACAGCAGGTT
AAGAACAAAAGGAAGACAAG

Downstream 100 bases:

>100_bases
GGAGACCGCCATGGCACTTTCAAGAGAACAACTGGCCCAGCGCGTCGCCAAAGAGCTTAAAGACGGCTACTACGTAAACT
TAGGCATCGGCATCCCTACC

Product: 3-oxoacid CoA-transferase

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MAGLYKVVDSYDQALAGLTDNMTIMVGGFGLCGIPEGLINQMVKLGTKGLTAISNNAGVDDFGLGLLLQNKQISTMIASY
VGENATFERQMLSGELNVILTPQGTLAEKIRAGGAGIPAFFTATGYGTPVAEGKETREIKGRHYVLEESLTADFALIRAW
KADTMGNLVFRKTAANFNPMMATAGKITVVEVEEIVEPGELDPDHIHTPGIYVDRIIKGSFEKRIEQRTVKKA

Sequences:

>Translated_233_residues
MAGLYKVVDSYDQALAGLTDNMTIMVGGFGLCGIPEGLINQMVKLGTKGLTAISNNAGVDDFGLGLLLQNKQISTMIASY
VGENATFERQMLSGELNVILTPQGTLAEKIRAGGAGIPAFFTATGYGTPVAEGKETREIKGRHYVLEESLTADFALIRAW
KADTMGNLVFRKTAANFNPMMATAGKITVVEVEEIVEPGELDPDHIHTPGIYVDRIIKGSFEKRIEQRTVKKA
>Mature_232_residues
AGLYKVVDSYDQALAGLTDNMTIMVGGFGLCGIPEGLINQMVKLGTKGLTAISNNAGVDDFGLGLLLQNKQISTMIASYV
GENATFERQMLSGELNVILTPQGTLAEKIRAGGAGIPAFFTATGYGTPVAEGKETREIKGRHYVLEESLTADFALIRAWK
ADTMGNLVFRKTAANFNPMMATAGKITVVEVEEIVEPGELDPDHIHTPGIYVDRIIKGSFEKRIEQRTVKKA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=239, Percent_Identity=59.4142259414226, Blast_Score=290, Evalue=6e-79,
Organism=Homo sapiens, GI11545841, Length=234, Percent_Identity=53.8461538461538, Blast_Score=241, Evalue=5e-64,
Organism=Escherichia coli, GI1788551, Length=198, Percent_Identity=50.5050505050505, Blast_Score=202, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17531517, Length=243, Percent_Identity=54.7325102880658, Blast_Score=271, Evalue=2e-73,
Organism=Drosophila melanogaster, GI21358325, Length=241, Percent_Identity=54.7717842323651, Blast_Score=257, Evalue=4e-69,
Organism=Drosophila melanogaster, GI24655794, Length=241, Percent_Identity=54.7717842323651, Blast_Score=257, Evalue=5e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25085; Mature: 24954

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLYKVVDSYDQALAGLTDNMTIMVGGFGLCGIPEGLINQMVKLGTKGLTAISNNAGVD
CCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCC
DFGLGLLLQNKQISTMIASYVGENATFERQMLSGELNVILTPQGTLAEKIRAGGAGIPAF
CCCCEEEEECCHHHHHHHHHHCCCCHHHHHHHCCCCEEEECCCCHHHHHHHCCCCCCCCE
FTATGYGTPVAEGKETREIKGRHYVLEESLTADFALIRAWKADTMGNLVFRKTAANFNPM
EEECCCCCCCCCCCCHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
MATAGKITVVEVEEIVEPGELDPDHIHTPGIYVDRIIKGSFEKRIEQRTVKKA
EECCCCEEEEEHHHHCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGLYKVVDSYDQALAGLTDNMTIMVGGFGLCGIPEGLINQMVKLGTKGLTAISNNAGVD
CHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCC
DFGLGLLLQNKQISTMIASYVGENATFERQMLSGELNVILTPQGTLAEKIRAGGAGIPAF
CCCCEEEEECCHHHHHHHHHHCCCCHHHHHHHCCCCEEEECCCCHHHHHHHCCCCCCCCE
FTATGYGTPVAEGKETREIKGRHYVLEESLTADFALIRAWKADTMGNLVFRKTAANFNPM
EEECCCCCCCCCCCCHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
MATAGKITVVEVEEIVEPGELDPDHIHTPGIYVDRIIKGSFEKRIEQRTVKKA
EECCCCEEEEEHHHHCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]