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The map label for this gene is ampC [H]

Identifier: 119774488

GI number: 119774488

Start: 1640228

End: 1641382

Strand: Reverse

Name: ampC [H]

Synonym: Sama_1351

Alternate gene names: 119774488

Gene position: 1641382-1640228 (Counterclockwise)

Preceding gene: 119774489

Following gene: 119774487

Centisome position: 38.12

GC content: 40.0

Gene sequence:

>1155_bases
GTGAAACTACTCAAATTAACCTTATTAATTATCTACTTTCTTTCTTGCACTGTGAATGCCGAAGAACGTTATGCGTTTTT
AGAAAACGAAATCACATTGTTTATGAAAAACAATGATATACCAGCTGTCACTGTAGGGGTAATAGAGAACGGTGATATAC
AGTTTGAAAAAGCTTACGGGACATACAGCAGAGAGAATATAAAGCCAGTTACAACTGATAGCTTATTTCAGATAGGTTCT
CAAACGAAGGTGATTACCAGTTTAATTACACTCGCCGCAGTGGAAGACGGAATACTAAAACTGGATGATAATCTGGATAC
TTTACTTCCTGATTTGTTCTCTTCTATAGACAAAAATACACTACAGAAAATAACCATTGATACCTTGCTAAGTCATCGCT
CAGGTCTTCCAAACTACCCAAAAAATGTCACACGTATAGATGGTGATCCTATGGAGGGAGGATACAGCGAAGCTCAACTG
CTGATCGCGCTTAAATCAACCATTTTAGATTTTGAACCCGGTAGCAAGTTTTCGTATTCGAATTTTAATTATGCACTTAT
TGGGTACATTCTTAGCAAGAAAACAGGGAAAACATATGAAACCCTTATTAATGAATATTTGCGTAAACGACTTGGTATCA
CCGAAGTCTACAGTCAGTTACAAGCTGATAGATCTTCCGTTGTTGTTACGCCCTACAGGAAAGATAACCGGTTAATAAAA
ACGAAGCCTTGGGAAATGGGCCTGCTTACGCCGCACGGTGGTTTGTATGCATCTAATCACGCTCTTTTGAAATTAATGGA
GCAGCAAATTTCAGCGTACCAAGTTTTCTTTAAAAACAGACAGGCTTCTCCTTTAGTTTCAACACAAACAAGTTATGCAA
CGGGACTTTATCCAGGGTTAAGCTATGGCTTTGGCATGTTCGAGGCAACGGCTGAGTTAGGTTTATATCCTGAAACCGTG
CTGTGGCACGGTGGAGATCTTGATGGCTTTGGCAGTGAGTATATTTTTTCACCAAGCTCAAAAGTTGGCATTGTGCTTTT
GACATCTAGTGGAGGCAGAGAATTTGTGCTCCTTGGAAGGAAATTGATGAATAGCCTTCTGACTGAGAAAGCTAACAAGT
CAATGCAGCCGACCGCTAACGCGTCGGCTGATTGA

Upstream 100 bases:

>100_bases
AATTACATGCAGGCTCCCGTCACTTCGTTCCGTATTTTAGCCTGCATGTACTTGCCCCTGCTTGGGGCGTTAGCTTTCAA
TTTAATTTCAAGGATGGAAC

Downstream 100 bases:

>100_bases
AGCGTTAGCTAAAAAAGGAGGCTATATGCCAAGAAAGAAGCAACTCAAAGTAAATGGAAGTGCAATCACGGGATTCAGTG
TGCAAGTTAAAACAGTTAAA

Product: beta-lactamase class C-like protein

Products: NA

Alternate protein names: Cephalosporinase [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MKLLKLTLLIIYFLSCTVNAEERYAFLENEITLFMKNNDIPAVTVGVIENGDIQFEKAYGTYSRENIKPVTTDSLFQIGS
QTKVITSLITLAAVEDGILKLDDNLDTLLPDLFSSIDKNTLQKITIDTLLSHRSGLPNYPKNVTRIDGDPMEGGYSEAQL
LIALKSTILDFEPGSKFSYSNFNYALIGYILSKKTGKTYETLINEYLRKRLGITEVYSQLQADRSSVVVTPYRKDNRLIK
TKPWEMGLLTPHGGLYASNHALLKLMEQQISAYQVFFKNRQASPLVSTQTSYATGLYPGLSYGFGMFEATAELGLYPETV
LWHGGDLDGFGSEYIFSPSSKVGIVLLTSSGGREFVLLGRKLMNSLLTEKANKSMQPTANASAD

Sequences:

>Translated_384_residues
MKLLKLTLLIIYFLSCTVNAEERYAFLENEITLFMKNNDIPAVTVGVIENGDIQFEKAYGTYSRENIKPVTTDSLFQIGS
QTKVITSLITLAAVEDGILKLDDNLDTLLPDLFSSIDKNTLQKITIDTLLSHRSGLPNYPKNVTRIDGDPMEGGYSEAQL
LIALKSTILDFEPGSKFSYSNFNYALIGYILSKKTGKTYETLINEYLRKRLGITEVYSQLQADRSSVVVTPYRKDNRLIK
TKPWEMGLLTPHGGLYASNHALLKLMEQQISAYQVFFKNRQASPLVSTQTSYATGLYPGLSYGFGMFEATAELGLYPETV
LWHGGDLDGFGSEYIFSPSSKVGIVLLTSSGGREFVLLGRKLMNSLLTEKANKSMQPTANASAD
>Mature_384_residues
MKLLKLTLLIIYFLSCTVNAEERYAFLENEITLFMKNNDIPAVTVGVIENGDIQFEKAYGTYSRENIKPVTTDSLFQIGS
QTKVITSLITLAAVEDGILKLDDNLDTLLPDLFSSIDKNTLQKITIDTLLSHRSGLPNYPKNVTRIDGDPMEGGYSEAQL
LIALKSTILDFEPGSKFSYSNFNYALIGYILSKKTGKTYETLINEYLRKRLGITEVYSQLQADRSSVVVTPYRKDNRLIK
TKPWEMGLLTPHGGLYASNHALLKLMEQQISAYQVFFKNRQASPLVSTQTSYATGLYPGLSYGFGMFEATAELGLYPETV
LWHGGDLDGFGSEYIFSPSSKVGIVLLTSSGGREFVLLGRKLMNSLLTEKANKSMQPTANASAD

Specific function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-C beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI87082101, Length=245, Percent_Identity=26.9387755102041, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533026, Length=180, Percent_Identity=31.6666666666667, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17550934, Length=254, Percent_Identity=25.9842519685039, Blast_Score=81, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001586
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 42644; Mature: 42644

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLKLTLLIIYFLSCTVNAEERYAFLENEITLFMKNNDIPAVTVGVIENGDIQFEKAYG
CHHHHHHHHHHHHHHCCCCCHHHHEEECCCEEEEEECCCCCEEEEEEEECCCEEEEECCC
TYSRENIKPVTTDSLFQIGSQTKVITSLITLAAVEDGILKLDDNLDTLLPDLFSSIDKNT
CCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHCHHH
LQKITIDTLLSHRSGLPNYPKNVTRIDGDPMEGGYSEAQLLIALKSTILDFEPGSKFSYS
HHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCHHHHHHHEEEHHHHEECCCCCCCCCC
NFNYALIGYILSKKTGKTYETLINEYLRKRLGITEVYSQLQADRSSVVVTPYRKDNRLIK
CCCCEEEEHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCEEEE
TKPWEMGLLTPHGGLYASNHALLKLMEQQISAYQVFFKNRQASPLVSTQTSYATGLYPGL
ECCCEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHCCCCCH
SYGFGMFEATAELGLYPETVLWHGGDLDGFGSEYIFSPSSKVGIVLLTSSGGREFVLLGR
HHCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEECCCCCEEEEEEECCCCCEEEEHHH
KLMNSLLTEKANKSMQPTANASAD
HHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKLLKLTLLIIYFLSCTVNAEERYAFLENEITLFMKNNDIPAVTVGVIENGDIQFEKAYG
CHHHHHHHHHHHHHHCCCCCHHHHEEECCCEEEEEECCCCCEEEEEEEECCCEEEEECCC
TYSRENIKPVTTDSLFQIGSQTKVITSLITLAAVEDGILKLDDNLDTLLPDLFSSIDKNT
CCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHCHHH
LQKITIDTLLSHRSGLPNYPKNVTRIDGDPMEGGYSEAQLLIALKSTILDFEPGSKFSYS
HHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCHHHHHHHEEEHHHHEECCCCCCCCCC
NFNYALIGYILSKKTGKTYETLINEYLRKRLGITEVYSQLQADRSSVVVTPYRKDNRLIK
CCCCEEEEHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCEEEE
TKPWEMGLLTPHGGLYASNHALLKLMEQQISAYQVFFKNRQASPLVSTQTSYATGLYPGL
ECCCEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHCCCCCH
SYGFGMFEATAELGLYPETVLWHGGDLDGFGSEYIFSPSSKVGIVLLTSSGGREFVLLGR
HHCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEECCCCCEEEEEEECCCCCEEEEHHH
KLMNSLLTEKANKSMQPTANASAD
HHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA