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The map label for this gene is sdaA [H]

Identifier: 119774462

GI number: 119774462

Start: 1613908

End: 1615284

Strand: Reverse

Name: sdaA [H]

Synonym: Sama_1325

Alternate gene names: 119774462

Gene position: 1615284-1613908 (Counterclockwise)

Preceding gene: 119774466

Following gene: 119774460

Centisome position: 37.51

GC content: 54.18

Gene sequence:

>1377_bases
ATGATCAGTGTATTTGACATATTTAAAATTGGAATAGGTCCTTCCAGTTCTCATACGGTCGGCCCCATGAAGGCTGGCAA
AGAATTCGTTGCCCGTGTGGAAAGCATGGGGTTGCTGGCACAGGTTGATGAACTGCGTGCCGAGCTGTTTGGCTCATTGG
GCCAAACAGGTAAAGGCCACGGTACCGGCAAAGCCGTGATCCTGGGCCTCATGGGGGAAGATCCTGAAACCGTTGATACC
GACGCTATCGATGGCATTCTGGCCCAGGTGTCGAGTCAGGAAACCCTGACGCTGGCACAGGGTAAAACCGTTAAGTTTAC
CCGTGAAGACGGCATCATCTACCACAGACGCAAGACGCTTCCCGCCCATGCCAACGCCATGACCCTCTATGCCTTTGCCG
GTGGTGAGTGCCTGTATCAGCGTACCTACTACTCGGTAGGCGGTGGCTTTGTGCTGGATGAAGATCAAATCGAGCGTAAA
AATCCGTCACCCGCCACGCCCATCAAGGCAGCACCTTATGATTTCAACAGTGCCCAACAGCTACTGGAAATGTGCACTGA
CAATGGCTTGTCGATTTCATCCCTGATGATGCAAAACGAGCTGACGCTGGCCAGCGAAGACGACGTCAAGGCGCGTTTGT
GGCATATCTGGCAGACCATGAAAACCTGCATTGAGAAAGGCTACAAGAAAGAAGGCATGCTCCCGGGAGGGCTTAAGCTG
CGCCGTCGTGCTCCTGGCCTTTATCGTCGCCTGCAAGCCGAAGGCCGCAACAACGTGGACCCGCTGAATGCCATGGACTG
GGTAGACCTGTTTGCATTATCGGTGAACGAGCAAAATGCGGCCGGCGACCGTGTGGTAACGGCCCCCACCAATGGTGCTG
CGGGTATTATCCCGGCGGTACTCTGCTATTTTGATACCTTTGTGCAGCAAGTCGATGTGGATATTTGCGCACGTTATCTC
CTGACTGCCGCTGCCATTGGCATTCTGTACAAGAAAAACGCCTCTATTTCTGGCGCTGAAGTGGGCTGTCAGGGCGAGGT
GGGCGTTGCCTGCTCCATGGCTGCTGCAGCACTCACCGAAATCATGGGTGGCACGGTTGAGCATGTTGAAAATGCCGCCG
AGATTGGTATGGAGCATAACCTGGGCCTCACCTGTGACCCGGTAGGTGGCTTGGTACAGGTTCCCTGCATTGAGCGTAAC
GCCATGGGGGCAGTCAAGGCCATCAATGCCTCGCGTCTGGCACTTCGTGGCGATGGCAACCATAAGGTGTCTCTGGACAA
GGTAATTAAAACCATGATGGACACCGGCCGGGATATGCGCAGTAAATACAAGGAAACCGCCAAGGGTGGTCTGGCTGTTA
ACATAGTTGAGTGTTAA

Upstream 100 bases:

>100_bases
CAGAGGAGACCAGCCGAGGTTACCGCAAAGCACTCCGGTGAGCGAGCAAGCATCGGACAGACGACTAAAATAACAACTAC
ATCCAAACAGGGCCCAAGCT

Downstream 100 bases:

>100_bases
TTCTCACTCCATAAAAAATCCCGCTTGGTGCGGGATTTTTTATGGGCGCAAGCCAACTCAGCGGATTGGTAACTCTCTGT
CGGCAAACATCTCTTCAATG

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MISVFDIFKIGIGPSSSHTVGPMKAGKEFVARVESMGLLAQVDELRAELFGSLGQTGKGHGTGKAVILGLMGEDPETVDT
DAIDGILAQVSSQETLTLAQGKTVKFTREDGIIYHRRKTLPAHANAMTLYAFAGGECLYQRTYYSVGGGFVLDEDQIERK
NPSPATPIKAAPYDFNSAQQLLEMCTDNGLSISSLMMQNELTLASEDDVKARLWHIWQTMKTCIEKGYKKEGMLPGGLKL
RRRAPGLYRRLQAEGRNNVDPLNAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAVLCYFDTFVQQVDVDICARYL
LTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAAALTEIMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERN
AMGAVKAINASRLALRGDGNHKVSLDKVIKTMMDTGRDMRSKYKETAKGGLAVNIVEC

Sequences:

>Translated_458_residues
MISVFDIFKIGIGPSSSHTVGPMKAGKEFVARVESMGLLAQVDELRAELFGSLGQTGKGHGTGKAVILGLMGEDPETVDT
DAIDGILAQVSSQETLTLAQGKTVKFTREDGIIYHRRKTLPAHANAMTLYAFAGGECLYQRTYYSVGGGFVLDEDQIERK
NPSPATPIKAAPYDFNSAQQLLEMCTDNGLSISSLMMQNELTLASEDDVKARLWHIWQTMKTCIEKGYKKEGMLPGGLKL
RRRAPGLYRRLQAEGRNNVDPLNAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAVLCYFDTFVQQVDVDICARYL
LTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAAALTEIMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERN
AMGAVKAINASRLALRGDGNHKVSLDKVIKTMMDTGRDMRSKYKETAKGGLAVNIVEC
>Mature_458_residues
MISVFDIFKIGIGPSSSHTVGPMKAGKEFVARVESMGLLAQVDELRAELFGSLGQTGKGHGTGKAVILGLMGEDPETVDT
DAIDGILAQVSSQETLTLAQGKTVKFTREDGIIYHRRKTLPAHANAMTLYAFAGGECLYQRTYYSVGGGFVLDEDQIERK
NPSPATPIKAAPYDFNSAQQLLEMCTDNGLSISSLMMQNELTLASEDDVKARLWHIWQTMKTCIEKGYKKEGMLPGGLKL
RRRAPGLYRRLQAEGRNNVDPLNAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAVLCYFDTFVQQVDVDICARYL
LTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAAALTEIMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERN
AMGAVKAINASRLALRGDGNHKVSLDKVIKTMMDTGRDMRSKYKETAKGGLAVNIVEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=459, Percent_Identity=56.4270152505447, Blast_Score=530, Evalue=1e-152,
Organism=Escherichia coli, GI1789161, Length=459, Percent_Identity=54.2483660130719, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI48994925, Length=457, Percent_Identity=55.7986870897155, Blast_Score=504, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49129; Mature: 49129

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVFDIFKIGIGPSSSHTVGPMKAGKEFVARVESMGLLAQVDELRAELFGSLGQTGKGH
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTGKAVILGLMGEDPETVDTDAIDGILAQVSSQETLTLAQGKTVKFTREDGIIYHRRKTL
CCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCEEEEECCCC
PAHANAMTLYAFAGGECLYQRTYYSVGGGFVLDEDQIERKNPSPATPIKAAPYDFNSAQQ
CCCCCEEEEEEEECCCEEEHHHHEECCCCEEECCHHHHCCCCCCCCCCCCCCCCCHHHHH
LLEMCTDNGLSISSLMMQNELTLASEDDVKARLWHIWQTMKTCIEKGYKKEGMLPGGLKL
HHHHHCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
RRRAPGLYRRLQAEGRNNVDPLNAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAV
HHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHEEECCCCCCCCCEEEECCCCCCHHHHHHH
LCYFDTFVQQVDVDICARYLLTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAAALTE
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERNAMGAVKAINASRLALRGDGN
HHCCHHHHHHHHHHHCCCCCCCEEECCCCCEEECCCCCCCCCCHHHCCCCCEEEEECCCC
HKVSLDKVIKTMMDTGRDMRSKYKETAKGGLAVNIVEC
CEEEHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECC
>Mature Secondary Structure
MISVFDIFKIGIGPSSSHTVGPMKAGKEFVARVESMGLLAQVDELRAELFGSLGQTGKGH
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTGKAVILGLMGEDPETVDTDAIDGILAQVSSQETLTLAQGKTVKFTREDGIIYHRRKTL
CCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCEEEEECCCC
PAHANAMTLYAFAGGECLYQRTYYSVGGGFVLDEDQIERKNPSPATPIKAAPYDFNSAQQ
CCCCCEEEEEEEECCCEEEHHHHEECCCCEEECCHHHHCCCCCCCCCCCCCCCCCHHHHH
LLEMCTDNGLSISSLMMQNELTLASEDDVKARLWHIWQTMKTCIEKGYKKEGMLPGGLKL
HHHHHCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
RRRAPGLYRRLQAEGRNNVDPLNAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAV
HHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHEEECCCCCCCCCEEEECCCCCCHHHHHHH
LCYFDTFVQQVDVDICARYLLTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAAALTE
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERNAMGAVKAINASRLALRGDGN
HHCCHHHHHHHHHHHCCCCCCCEEECCCCCEEECCCCCCCCCCHHHCCCCCEEEEECCCC
HKVSLDKVIKTMMDTGRDMRSKYKETAKGGLAVNIVEC
CEEEHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]